Click here to switch to the map view.

The map label for this gene is celD [H]

Identifier: 152969787

GI number: 152969787

Start: 1384069

End: 1384893

Strand: Direct

Name: celD [H]

Synonym: KPN_01233

Alternate gene names: 152969787

Gene position: 1384069-1384893 (Clockwise)

Preceding gene: 152969786

Following gene: 152969788

Centisome position: 26.04

GC content: 47.76

Gene sequence:

>825_bases
ATGATGACCACCGAGATCAGTACCGCCAGAGAACAACAGCTGTTCAACGGGAAGAACTTTCATGTGGTCATCTATAACAA
AACGGAAAGCGTGAGCGGGCTTCACCAGCATGATTACTACGAATTTACCGTGGTGTTAACCGGGCGCTATTACCAGGAGA
TCAATGGCAAACGGGTGCTGCTGGAGCGCGGGGATTTCGTCTTTATCCCGATGGGCTCGCACCACCAGAGCTTTTACGAG
TTCGGGGCGACGCGCATCCTTAACGTCGGCATCAGCAGACGCTTCTTTGAGAAACACTACCTGCCACTGCTGCCGTTTGG
TCTGGTGGCTTCGCAAGTCTACGCCGTGCAGAGCGCTTTTCTCGGCTACGTTGAGTCGGTCATCGCCTCACTCAATTTTC
GCGAAACGGAATTTGACGAATTTATCGAGCTGGTCTCCTTTTATGTCATTAACCGTTTACGCCACTATCGTGAAGAGCCG
GTTGCCGACGTGACGCCGCAATGGTTAAAAAATACCGTGGAAGCCATGCATGATAAGCTGAAATTCGGTGAAGGCGCTCT
CGAAAATATGGTTCGCTTATCCGGAAAAACGCAGGAATATTTAACCCGGGCGACCCAGCGCTATTATGGTAAAACACCGA
TGCAGATAATTAATGATATCCGTATCAACTTTGCCAAAAAACAGCTGGAAATTACCAATTATTCGGTGACGGATATTGCG
TATGAATCAGGTTACAGCAGCCCGAGCTTGTTTATTAAAACCTTTAAAAAACTGACGTCGTTTACGCCGAGCAGTTATCG
CAAACATTTGACCAGTATTAATTAA

Upstream 100 bases:

>100_bases
CCATCTGATGACCTCCATGCTGGCTCGTGAGCTGGTGGCCGAATTGATTGAGCTGCACGAGAAGGTACAATAGGCCATCG
CGACGATGAGGCAGCCCAGA

Downstream 100 bases:

>100_bases
ACCCGCGCGGCGTTCGCCGCCAGGTTTATACCGAAAATCATTCAAGTTAACTGTCCGCATTGTTGCGGAGAGCGGCCTGC
GTCCAGGCGCAGCGCCTAAG

Product: DNA-binding transcriptional regulator ChbR

Products: NA

Alternate protein names: Chb operon repressor [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEINGKRVLLERGDFVFIPMGSHHQSFYE
FGATRILNVGISRRFFEKHYLPLLPFGLVASQVYAVQSAFLGYVESVIASLNFRETEFDEFIELVSFYVINRLRHYREEP
VADVTPQWLKNTVEAMHDKLKFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYSVTDIA
YESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN

Sequences:

>Translated_274_residues
MMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEINGKRVLLERGDFVFIPMGSHHQSFYE
FGATRILNVGISRRFFEKHYLPLLPFGLVASQVYAVQSAFLGYVESVIASLNFRETEFDEFIELVSFYVINRLRHYREEP
VADVTPQWLKNTVEAMHDKLKFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYSVTDIA
YESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN
>Mature_274_residues
MMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEINGKRVLLERGDFVFIPMGSHHQSFYE
FGATRILNVGISRRFFEKHYLPLLPFGLVASQVYAVQSAFLGYVESVIASLNFRETEFDEFIELVSFYVINRLRHYREEP
VADVTPQWLKNTVEAMHDKLKFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYSVTDIA
YESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN

Specific function: Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presen

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788030, Length=270, Percent_Identity=83.3333333333333, Blast_Score=476, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013096
- InterPro:   IPR011051
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF07883 Cupin_2; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31912; Mature: 31912

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEINGKRVL
CCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHCCCEEEEEEEECHHHHHCCCCEEE
LERGDFVFIPMGSHHQSFYEFGATRILNVGISRRFFEKHYLPLLPFGLVASQVYAVQSAF
EECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LGYVESVIASLNFRETEFDEFIELVSFYVINRLRHYREEPVADVTPQWLKNTVEAMHDKL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
KFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYSVTDIA
HCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCHHHHH
YESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN
HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MMTTEISTAREQQLFNGKNFHVVIYNKTESVSGLHQHDYYEFTVVLTGRYYQEINGKRVL
CCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHCCCEEEEEEEECHHHHHCCCCEEE
LERGDFVFIPMGSHHQSFYEFGATRILNVGISRRFFEKHYLPLLPFGLVASQVYAVQSAF
EECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LGYVESVIASLNFRETEFDEFIELVSFYVINRLRHYREEPVADVTPQWLKNTVEAMHDKL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
KFGEGALENMVRLSGKTQEYLTRATQRYYGKTPMQIINDIRINFAKKQLEITNYSVTDIA
HCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCHHHHH
YESGYSSPSLFIKTFKKLTSFTPSSYRKHLTSIN
HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 9405618 [H]