BacMap

Definition	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome.
Accession	NC_009648
Length	5,315,120

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The map label for this gene is astD

Identifier: 152969777

GI number: 152969777

Start: 1374431

End: 1375909

Strand: Direct

Name: astD

Synonym: KPN_01223

Alternate gene names: 152969777

Gene position: 1374431-1375909 (Clockwise)

Preceding gene: 152969776

Following gene: 152969778

Centisome position: 25.86

GC content: 66.73

Gene sequence:

>1479_bases
ATGAGTCTGTGGATTAACGGCGAGTGGCGGCCCGGCCGTGGGCCAGGTTTCAGTAAACAGGATCCGGTTAACCTGAAGGT
TGTCTGGCAGGGCGAGGCGGCGGATGCCGGGCAGGTTGCCGAGGCGGTGGCGGCTGCCCGCCAGGCGTTCCCGTCCTGGG
CGCGGCTGCCGTTTGCCGCCCGTCAGGCGATCGTTGAAAAGTTTGCCGCTCTGCTGGAAGCCAGTAAGGCGGAGCTGACG
GCGGTTATCGGCGCCGAGACCGGAAAGCCGCGCTGGGAGGCGGCCGGGGAAGTGACGGCGATGATCAACAAGGTGGCGAT
CTCGGTGAAGGCCTACCACGTCCGCACCGGCGAACAGCACAGCGACCTGCCCGACGGCGCCGCCACGCTGCGTCACCGGC
CGCACGGCGTACTGGCGGTGTTTGGCCCCTATAACTTTCCCGGCCATCTGCCGAACGGGCACATCGTGCCGGCGCTGTTG
GCGGGCAATACCGTGGTCTTTAAACCCAGCGAACTCACCCCGCGCAGCGGCGAAGCGGTGGTGAAACTATGGCAGCAGGC
CGGCCTGCCCGCCGGGGTGCTCAACCTGGTGCAGGGCGGTCGGGAAACCGGCGAGGCGCTCAGCGGTCAGGCGGATATCG
ACGGGCTGCTGTTTACCGGCAGCTCAACCACCGGTTTTCATCTGCATCGCCAGCTGGCCGGGCAACCGCAGAAGATCCTC
GCGCTGGAGATGGGCGGCAATAACCCGCTGATCGTCGACGATCCGCGGGACGTGGATGCCGTGGTGCATCTGACCATCCA
GTCCGCCTTTATTACCGCTGGCCAGCGCTGCACCTGCGCCCGGCGTCTGCTGGTCCGACGCGGAGAGGCGGGCGATGCCT
TCCTCTCCCGGCTGGTGACGGTGAGCCAACGGCTGATCCCGGCGGCGTGGGACGCCGAGCCGCAGCCGTTTCTCGGCGGG
CTTATCTCTGAACAAGCCGCGCAGAAAGTGCATCAGGCCTGGCTGCAGCGGGTCGCCGCTGGCGCGGTCACCCTGCTGGA
GCCGCGGTTATTGCAGGCCGGGACGTCGTTGCTAACCCCGGGGATTGTCGACATGAGCGACGTGGCCAATGTCGAGGATG
AAGAGGTGTTTGGCCCGCTGCTTGGGGTCTGGCGCTACGACACGTTCGAGGAGGCGATTGCCTTAGCCAACGCTACCCGC
TTCGGCCTCTCCTGTGGGTTAATCTCCCCGGAACGGGAGAAGTTCGATCGACTGCTGCTTGAGGCGCGGGCAGGGATAGT
TAACTGGAACAAACCGCTGACCGGGGCGGCGAGTACCGCGCCGTTCGGCGGCACCGGGGCGTCCGGTAACCATCGTCCGG
GGGCCTGGTATGCCGCCGATTATTGCGCCTGGCCGATGGCCAGCCTTGAATCGCCGACCCTGACGCTGCCCGCCAGCCTG
AGCCCGGGGCTCGACTTTCTGGCCGGGGAGGCGTCATGA

Upstream 100 bases:

>100_bases
GCGAGACCCTGACCCTCAGCGCCCGCGAACTGGATATGCTGAAGTGTCATGCCGGCGACCAGGTGCGCATGGTGCGCCTG
ATCCCTGAGGAGAAAACTGC

Downstream 100 bases:

>100_bases
CCGCCCGCGAAGTCAACTTTGACGGTCTGCTCGGGCTGACCCATCACTACGCCGGGCTCTCCTTTGGCAATGAGGCTTCC
ACCCGGCATCGCTATCGGGT

Product: aldehyde dehyrogenase

Products: NA

Alternate protein names: Succinylglutamic semialdehyde dehydrogenase; SGSD

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSLWINGEWRPGRGPGFSKQDPVNLKVVWQGEAADAGQVAEAVAAARQAFPSWARLPFAARQAIVEKFAALLEASKAELT
AVIGAETGKPRWEAAGEVTAMINKVAISVKAYHVRTGEQHSDLPDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
AGNTVVFKPSELTPRSGEAVVKLWQQAGLPAGVLNLVQGGRETGEALSGQADIDGLLFTGSSTTGFHLHRQLAGQPQKIL
ALEMGGNNPLIVDDPRDVDAVVHLTIQSAFITAGQRCTCARRLLVRRGEAGDAFLSRLVTVSQRLIPAAWDAEPQPFLGG
LISEQAAQKVHQAWLQRVAAGAVTLLEPRLLQAGTSLLTPGIVDMSDVANVEDEEVFGPLLGVWRYDTFEEAIALANATR
FGLSCGLISPEREKFDRLLLEARAGIVNWNKPLTGAASTAPFGGTGASGNHRPGAWYAADYCAWPMASLESPTLTLPASL
SPGLDFLAGEAS

Sequences:

>Translated_492_residues
MSLWINGEWRPGRGPGFSKQDPVNLKVVWQGEAADAGQVAEAVAAARQAFPSWARLPFAARQAIVEKFAALLEASKAELT
AVIGAETGKPRWEAAGEVTAMINKVAISVKAYHVRTGEQHSDLPDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
AGNTVVFKPSELTPRSGEAVVKLWQQAGLPAGVLNLVQGGRETGEALSGQADIDGLLFTGSSTTGFHLHRQLAGQPQKIL
ALEMGGNNPLIVDDPRDVDAVVHLTIQSAFITAGQRCTCARRLLVRRGEAGDAFLSRLVTVSQRLIPAAWDAEPQPFLGG
LISEQAAQKVHQAWLQRVAAGAVTLLEPRLLQAGTSLLTPGIVDMSDVANVEDEEVFGPLLGVWRYDTFEEAIALANATR
FGLSCGLISPEREKFDRLLLEARAGIVNWNKPLTGAASTAPFGGTGASGNHRPGAWYAADYCAWPMASLESPTLTLPASL
SPGLDFLAGEAS
>Mature_491_residues
SLWINGEWRPGRGPGFSKQDPVNLKVVWQGEAADAGQVAEAVAAARQAFPSWARLPFAARQAIVEKFAALLEASKAELTA
VIGAETGKPRWEAAGEVTAMINKVAISVKAYHVRTGEQHSDLPDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLA
GNTVVFKPSELTPRSGEAVVKLWQQAGLPAGVLNLVQGGRETGEALSGQADIDGLLFTGSSTTGFHLHRQLAGQPQKILA
LEMGGNNPLIVDDPRDVDAVVHLTIQSAFITAGQRCTCARRLLVRRGEAGDAFLSRLVTVSQRLIPAAWDAEPQPFLGGL
ISEQAAQKVHQAWLQRVAAGAVTLLEPRLLQAGTSLLTPGIVDMSDVANVEDEEVFGPLLGVWRYDTFEEAIALANATRF
GLSCGLISPEREKFDRLLLEARAGIVNWNKPLTGAASTAPFGGTGASGNHRPGAWYAADYCAWPMASLESPTLTLPASLS
PGLDFLAGEAS

Specific function: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. AstD subfamily

Homologues:

Organism=Homo sapiens, GI12007648, Length=474, Percent_Identity=31.0126582278481, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI4507229, Length=465, Percent_Identity=32.4731182795699, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI153266822, Length=476, Percent_Identity=29.6218487394958, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI25777721, Length=478, Percent_Identity=31.5899581589958, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI25777724, Length=463, Percent_Identity=30.4535637149028, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI115387104, Length=451, Percent_Identity=28.159645232816, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI21361176, Length=473, Percent_Identity=30.4439746300211, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI25777730, Length=465, Percent_Identity=29.247311827957, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI25777732, Length=461, Percent_Identity=28.1995661605206, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI25952152, Length=462, Percent_Identity=29.4372294372294, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI11095441, Length=409, Percent_Identity=27.6283618581907, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI25777728, Length=423, Percent_Identity=29.5508274231678, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI310128093, Length=456, Percent_Identity=27.8508771929825, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI188035924, Length=456, Percent_Identity=27.6315789473684, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310128103, Length=456, Percent_Identity=27.6315789473684, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI21614513, Length=476, Percent_Identity=28.781512605042, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI238814322, Length=417, Percent_Identity=27.5779376498801, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI25777726, Length=461, Percent_Identity=27.114967462039, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI25777736, Length=440, Percent_Identity=28.6363636363636, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI25777734, Length=440, Percent_Identity=28.6363636363636, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI238859541, Length=440, Percent_Identity=28.6363636363636, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI310128091, Length=456, Percent_Identity=26.3157894736842, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI4502043, Length=434, Percent_Identity=26.7281105990783, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI238814371, Length=434, Percent_Identity=26.7281105990783, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI206597441, Length=427, Percent_Identity=26.6978922716628, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI206597439, Length=427, Percent_Identity=26.6978922716628, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI22907049, Length=427, Percent_Identity=26.6978922716628, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI301500698, Length=280, Percent_Identity=31.0714285714286, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI71773324, Length=338, Percent_Identity=28.698224852071, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI310128087, Length=287, Percent_Identity=28.9198606271777, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI73695881, Length=346, Percent_Identity=27.4566473988439, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI73695879, Length=346, Percent_Identity=27.4566473988439, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI310128089, Length=277, Percent_Identity=29.2418772563177, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI4557303, Length=418, Percent_Identity=23.9234449760766, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI73466520, Length=427, Percent_Identity=24.3559718969555, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI310128095, Length=302, Percent_Identity=27.8145695364238, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI310128097, Length=244, Percent_Identity=29.9180327868852, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI310128101, Length=225, Percent_Identity=26.2222222222222, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI310128099, Length=225, Percent_Identity=26.2222222222222, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1788042, Length=486, Percent_Identity=77.9835390946502, Blast_Score=785, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=465, Percent_Identity=33.7634408602151, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787558, Length=465, Percent_Identity=33.1182795698925, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787684, Length=416, Percent_Identity=31.9711538461538, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1787250, Length=433, Percent_Identity=30.9468822170901, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786504, Length=462, Percent_Identity=28.7878787878788, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87081896, Length=473, Percent_Identity=31.9238900634249, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787715, Length=470, Percent_Identity=28.7234042553192, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87082295, Length=473, Percent_Identity=28.9640591966173, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI87081926, Length=420, Percent_Identity=24.047619047619, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25144435, Length=498, Percent_Identity=30.1204819277108, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17534119, Length=472, Percent_Identity=28.3898305084746, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17562198, Length=493, Percent_Identity=28.8032454361055, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI25143874, Length=424, Percent_Identity=30.8962264150943, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI25143876, Length=424, Percent_Identity=30.8962264150943, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17551164, Length=432, Percent_Identity=29.3981481481481, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=422, Percent_Identity=30.8056872037915, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71995606, Length=446, Percent_Identity=29.372197309417, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32564736, Length=436, Percent_Identity=29.5871559633028, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71995613, Length=403, Percent_Identity=29.5285359801489, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71986308, Length=447, Percent_Identity=27.0693512304251, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI133930964, Length=459, Percent_Identity=29.1938997821351, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17564084, Length=435, Percent_Identity=24.5977011494253, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32566756, Length=441, Percent_Identity=25.1700680272109, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25146394, Length=441, Percent_Identity=25.1700680272109, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=441, Percent_Identity=25.1700680272109, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17534447, Length=436, Percent_Identity=25.4587155963303, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564151, Length=400, Percent_Identity=25.25, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115532534, Length=335, Percent_Identity=26.2686567164179, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990744, Length=259, Percent_Identity=27.4131274131274, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320917, Length=468, Percent_Identity=30.982905982906, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6319478, Length=473, Percent_Identity=29.1754756871036, Blast_Score=169, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=458, Percent_Identity=27.7292576419214, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6323821, Length=469, Percent_Identity=26.6524520255864, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323822, Length=476, Percent_Identity=27.1008403361345, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325196, Length=461, Percent_Identity=27.114967462039, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321826, Length=489, Percent_Identity=28.0163599182004, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321828, Length=450, Percent_Identity=23.7777777777778, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323757, Length=442, Percent_Identity=22.6244343891403, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281362580, Length=457, Percent_Identity=31.7286652078775, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI62472918, Length=457, Percent_Identity=31.7286652078775, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI62472926, Length=457, Percent_Identity=31.7286652078775, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI62472936, Length=457, Percent_Identity=31.7286652078775, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI21356737, Length=457, Percent_Identity=31.7286652078775, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI20129399, Length=474, Percent_Identity=28.0590717299578, Blast_Score=165, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24650465, Length=467, Percent_Identity=29.3361884368308, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24666674, Length=469, Percent_Identity=26.865671641791, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24638876, Length=466, Percent_Identity=27.2532188841202, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24638878, Length=466, Percent_Identity=27.2532188841202, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24585660, Length=465, Percent_Identity=26.6666666666667, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24668425, Length=448, Percent_Identity=26.7857142857143, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668417, Length=448, Percent_Identity=26.7857142857143, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668413, Length=448, Percent_Identity=26.7857142857143, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281360301, Length=439, Percent_Identity=24.1457858769932, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281360299, Length=430, Percent_Identity=24.4186046511628, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281360297, Length=430, Percent_Identity=24.4186046511628, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281360295, Length=430, Percent_Identity=24.4186046511628, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24586250, Length=430, Percent_Identity=24.4186046511628, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281360303, Length=439, Percent_Identity=23.6902050113895, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45552499, Length=430, Percent_Identity=23.953488372093, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28574525, Length=454, Percent_Identity=25.7709251101322, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571806, Length=436, Percent_Identity=24.5412844036697, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571802, Length=436, Percent_Identity=24.5412844036697, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571800, Length=436, Percent_Identity=24.5412844036697, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571798, Length=436, Percent_Identity=24.5412844036697, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571796, Length=436, Percent_Identity=24.5412844036697, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571794, Length=436, Percent_Identity=24.5412844036697, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTD_KLEP7 (A6T7T5)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001334886.1
- ProteinModelPortal:   A6T7T5
- SMR:   A6T7T5
- STRING:   A6T7T5
- GeneID:   5338809
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_01223
- eggNOG:   COG1012
- HOGENOM:   HBG752218
- OMA:   KAYHART
- ProtClustDB:   CLSK2400673
- HAMAP:   MF_01174
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017649
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699
- TIGRFAMs:   TIGR03240

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.71

Molecular weight: Translated: 52197; Mature: 52066

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 243-243 ACT_SITE 277-277

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLWINGEWRPGRGPGFSKQDPVNLKVVWQGEAADAGQVAEAVAAARQAFPSWARLPFAA
CEEEECCEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHCCHHH
RQAIVEKFAALLEASKAELTAVIGAETGKPRWEAAGEVTAMINKVAISVKAYHVRTGEQH
HHHHHHHHHHHHHCCHHHEEEEEECCCCCCCHHHCHHHHHHHHHHEEEEEEEEEECCCCC
SDLPDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPRSGEAV
CCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCHHH
VKLWQQAGLPAGVLNLVQGGRETGEALSGQADIDGLLFTGSSTTGFHLHRQLAGQPQKIL
HHHHHHCCCCHHHHHHHHCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEE
ALEMGGNNPLIVDDPRDVDAVVHLTIQSAFITAGQRCTCARRLLVRRGEAGDAFLSRLVT
EEEECCCCCEEEECCCCCCEEEEEEEHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
VSQRLIPAAWDAEPQPFLGGLISEQAAQKVHQAWLQRVAAGAVTLLEPRLLQAGTSLLTP
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHCCHHHCCC
GIVDMSDVANVEDEEVFGPLLGVWRYDTFEEAIALANATRFGLSCGLISPEREKFDRLLL
CCCCHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHH
EARAGIVNWNKPLTGAASTAPFGGTGASGNHRPGAWYAADYCAWPMASLESPTLTLPASL
HHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHCCHHHCCCCCEEECCCC
SPGLDFLAGEAS
CCCCHHHCCCCC
>Mature Secondary Structure 
SLWINGEWRPGRGPGFSKQDPVNLKVVWQGEAADAGQVAEAVAAARQAFPSWARLPFAA
EEEECCEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHCCHHH
RQAIVEKFAALLEASKAELTAVIGAETGKPRWEAAGEVTAMINKVAISVKAYHVRTGEQH
HHHHHHHHHHHHHCCHHHEEEEEECCCCCCCHHHCHHHHHHHHHHEEEEEEEEEECCCCC
SDLPDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPRSGEAV
CCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCHHH
VKLWQQAGLPAGVLNLVQGGRETGEALSGQADIDGLLFTGSSTTGFHLHRQLAGQPQKIL
HHHHHHCCCCHHHHHHHHCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEE
ALEMGGNNPLIVDDPRDVDAVVHLTIQSAFITAGQRCTCARRLLVRRGEAGDAFLSRLVT
EEEECCCCCEEEECCCCCCEEEEEEEHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
VSQRLIPAAWDAEPQPFLGGLISEQAAQKVHQAWLQRVAAGAVTLLEPRLLQAGTSLLTP
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHCCHHHCCC
GIVDMSDVANVEDEEVFGPLLGVWRYDTFEEAIALANATRFGLSCGLISPEREKFDRLLL
CCCCHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHH
EARAGIVNWNKPLTGAASTAPFGGTGASGNHRPGAWYAADYCAWPMASLESPTLTLPASL
HHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHCCHHHCCCCCEEECCCC
SPGLDFLAGEAS
CCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA