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The map label for this gene is alsR [H]

Identifier: 152969716

GI number: 152969716

Start: 1313952

End: 1314842

Strand: Direct

Name: alsR [H]

Synonym: KPN_01162

Alternate gene names: 152969716

Gene position: 1313952-1314842 (Clockwise)

Preceding gene: 152969713

Following gene: 152969719

Centisome position: 24.72

GC content: 62.4

Gene sequence:

>891_bases
ATGTCCTTGCGAGCGTTACGCCATTTTGTGGTCGTTGCCGAAGAGTTGCATATGCACCGGGCGGCGGAGCGGTTACATAT
CGCCCAGCCCGCCCTCAGTCAGCAGATTAAGCAGCTTGAGCAGCGCCTGGGCGTGGTGCTCTTTTCCCGCGCCAACCGCC
GTCTGACTCTGACCGCCGCGGGCGAGGCCTTTTTACACAAGACGCGGCTGGCGCTGGAAATGGCCGATCAGGCGGTGCTG
GACGCCCAGCGCACCGCGCGGGGCGAGCAGGGGAGGCTGCATTTGGGGTATGTCTCCAGCGCGATGTACGACAGTAAACT
GCCGGGGCTCCTGCGCCGGCTGCGCGCCGACTGGCCGGGGATTGAGCTGTCGCTGGTGCAGGGGGATGTGCAAATGCTCT
ACGAAGCGCTGTTGGATCTGCGTCTGGATATCGCCATCATCCGCGCGCCGCTGGCCTCGCCGCCGGACGCGCTGGTGGTC
AGGCCGTTTGTACGTGAAAAGCTCTGCCTGGCGCTCTATCAACAGCATCCGCTGGCCGGCGTGGGCGCGCTTAATCTGGC
CTCATTGCGCACTGACAACTGGATCTCGCTTGACGATCCGCAGGGCACCGGACTGGAGCAGGTTTTTATGGATGCCTGTC
GCGTCGCGGGCTTTACGCCGCAGGTGGCGCAGCGGATTAACGACGTTACCTCGATGATTAGCCTGGTCTCCGCCGGGGTG
GGAGTGGCGTTGGTTCCGCTCTCGGCGCGGGCCTTACGCCTTGATAACGTGGTGTATATCGATCTCCAGGATCGGCTGGC
GGAGAGTGAGCTGAGCATGGTTTACCACCGCCATATTCGTTCGGCGGTGGTAAGGAAAGTTATCTCGCTGCTTAATACCG
CTGAGCGATAG

Upstream 100 bases:

>100_bases
GATGCGCACAGTATGCTTCGCAGGCTAATGGTTATCAATTGCATCATTTATGCTTTATTGATAAGCTTTTTCTTATCAAT
TTGTAGGGAGGAGTCCGACC

Downstream 100 bases:

>100_bases
TCCCGGTTAGCTGGTCTTCAGGCGGCCAAAGCTGACAATCCTTGAGCGGCCCAGCTCTTTCGCCCGGTACAGCGCGGCAT
CCGCCGCGCGCAGCAGACTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSLRALRHFVVVAEELHMHRAAERLHIAQPALSQQIKQLEQRLGVVLFSRANRRLTLTAAGEAFLHKTRLALEMADQAVL
DAQRTARGEQGRLHLGYVSSAMYDSKLPGLLRRLRADWPGIELSLVQGDVQMLYEALLDLRLDIAIIRAPLASPPDALVV
RPFVREKLCLALYQQHPLAGVGALNLASLRTDNWISLDDPQGTGLEQVFMDACRVAGFTPQVAQRINDVTSMISLVSAGV
GVALVPLSARALRLDNVVYIDLQDRLAESELSMVYHRHIRSAVVRKVISLLNTAER

Sequences:

>Translated_296_residues
MSLRALRHFVVVAEELHMHRAAERLHIAQPALSQQIKQLEQRLGVVLFSRANRRLTLTAAGEAFLHKTRLALEMADQAVL
DAQRTARGEQGRLHLGYVSSAMYDSKLPGLLRRLRADWPGIELSLVQGDVQMLYEALLDLRLDIAIIRAPLASPPDALVV
RPFVREKLCLALYQQHPLAGVGALNLASLRTDNWISLDDPQGTGLEQVFMDACRVAGFTPQVAQRINDVTSMISLVSAGV
GVALVPLSARALRLDNVVYIDLQDRLAESELSMVYHRHIRSAVVRKVISLLNTAER
>Mature_295_residues
SLRALRHFVVVAEELHMHRAAERLHIAQPALSQQIKQLEQRLGVVLFSRANRRLTLTAAGEAFLHKTRLALEMADQAVLD
AQRTARGEQGRLHLGYVSSAMYDSKLPGLLRRLRADWPGIELSLVQGDVQMLYEALLDLRLDIAIIRAPLASPPDALVVR
PFVREKLCLALYQQHPLAGVGALNLASLRTDNWISLDDPQGTGLEQVFMDACRVAGFTPQVAQRINDVTSMISLVSAGVG
VALVPLSARALRLDNVVYIDLQDRLAESELSMVYHRHIRSAVVRKVISLLNTAER

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=278, Percent_Identity=36.3309352517986, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI2367136, Length=290, Percent_Identity=31.3793103448276, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788887, Length=292, Percent_Identity=31.8493150684932, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1790399, Length=279, Percent_Identity=29.7491039426523, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI157672245, Length=269, Percent_Identity=33.0855018587361, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=30.6772908366534, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=26.0162601626016, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787530, Length=284, Percent_Identity=26.056338028169, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787806, Length=254, Percent_Identity=27.9527559055118, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788481, Length=203, Percent_Identity=30.0492610837438, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786713, Length=292, Percent_Identity=25.6849315068493, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=247, Percent_Identity=25.1012145748988, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789204, Length=256, Percent_Identity=27.34375, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786401, Length=141, Percent_Identity=31.2056737588652, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=234, Percent_Identity=26.4957264957265, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=263, Percent_Identity=26.2357414448669, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790262, Length=226, Percent_Identity=27.4336283185841, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32852; Mature: 32721

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRALRHFVVVAEELHMHRAAERLHIAQPALSQQIKQLEQRLGVVLFSRANRRLTLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCEEEEEEC
GEAFLHKTRLALEMADQAVLDAQRTARGEQGRLHLGYVSSAMYDSKLPGLLRRLRADWPG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCHHHHHHHHCCCCC
IELSLVQGDVQMLYEALLDLRLDIAIIRAPLASPPDALVVRPFVREKLCLALYQQHPLAG
CEEEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEECHHHHHHHHHHHHHCCCCCC
VGALNLASLRTDNWISLDDPQGTGLEQVFMDACRVAGFTPQVAQRINDVTSMISLVSAGV
CCHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
GVALVPLSARALRLDNVVYIDLQDRLAESELSMVYHRHIRSAVVRKVISLLNTAER
CEEEEECCHHEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLRALRHFVVVAEELHMHRAAERLHIAQPALSQQIKQLEQRLGVVLFSRANRRLTLTAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCEEEEEEC
GEAFLHKTRLALEMADQAVLDAQRTARGEQGRLHLGYVSSAMYDSKLPGLLRRLRADWPG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCHHHHHHHHCCCCC
IELSLVQGDVQMLYEALLDLRLDIAIIRAPLASPPDALVVRPFVREKLCLALYQQHPLAG
CEEEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEECHHHHHHHHHHHHHCCCCCC
VGALNLASLRTDNWISLDDPQGTGLEQVFMDACRVAGFTPQVAQRINDVTSMISLVSAGV
CCHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
GVALVPLSARALRLDNVVYIDLQDRLAESELSMVYHRHIRSAVVRKVISLLNTAER
CEEEEECCHHEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]