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The map label for this gene is hutI [H]

Identifier: 152969349

GI number: 152969349

Start: 883418

End: 884635

Strand: Direct

Name: hutI [H]

Synonym: KPN_00792

Alternate gene names: 152969349

Gene position: 883418-884635 (Clockwise)

Preceding gene: 152969347

Following gene: 152969350

Centisome position: 16.62

GC content: 64.12

Gene sequence:

>1218_bases
ATGACTGAAGCCACTTCCGAACTCGTTATCTGGCGAAACGGGCGTCTCGCCACCCTGAACCCCGATCACGCTCAACCTTA
CGGCCTGCTGGAGCGCCACGCGCTGCTGGTGCGCGACGGCCGCATCGCGGCGATTGTCGCCGAAGATGACGTCCCCAGCG
GGCGCAGTATCGATCTTGAAGGCCGGTTGGTAACGCCGGGATTAATCGACTGCCACACCCATCTCGTCTTCGGCGGCAGC
CGGGCCCAGGAGTGGGAGCAGCGGCTGAACGGCGTGTCGTATCAAACCATCAGCGCCAGCGGCGGCGGCATTAACTCCAC
CGTGCGCGCCACGCGCGACAGCAGCGAAGCTGAACTACTGGCGCTGGCCCAGCCGCGTCTGGAACGCCTGCTGCGTGAAG
GGGTGACCACCCTGGAGATCAAATCCGGCTACGGCCTCGACCTGCCAAACGAACGCAAAATGCTGCGGGTCGCCCGACAA
CTGGCCGATCATAATGGCGTGGAACTGTCGGCGACGCTGCTCTCCGCCCACGCCACGCCGCCGGAATATCAAGGCGATGC
TGACGGCTATATTACGCTGGTCTGCGAGACCATTTTACCGACGCTGTGGCAGGAGGGACTGTTTGAAAGCGTTGACGTCT
TCTGCGAAAACGTCGGCTTCAGCCCGCAGCAAACTGAGCGCGTCTTTCAGGCGGCGCAGGCGCTGGGCATTCCGGTAAAA
GGCCACGTTGAGCAGCTCTCGTCGCTGGGCGGCGCGCAGCTGGTGAGCCGCTATCATGGGCTTTCCGCCGACCATATCGA
GTATCTGACGGAAGAGGGCGTGGCGGCGATGCGCGAAAGCGGCACCGTGGCAGCCCTGCTCCCCGGCGCATTCTACTTCC
TTAATGAAACCCGTAAACCGCCGGTCGAGCTGCTGCGCAAGTACCAGGTGCCGATGGCGGTGGCGACCGATTTCAACCCC
GGCACCAGCCCCTTCGCCAGCCTGCATCTGGCGATGAACATGGCCTGCGTTAAGTTTGGCCTGACGCCGGAGGAGGCGTG
GGCCGGGGTGACGCGCCATGCCGCGCGGGCGCTGGGGCGCCAGGCCAGCCACGGCCAGCTGGCGCCGGGCTTTGTCGCTA
ACTTCGCCATCTGGGATGCTGAGCATCCCGTCGAGATGGTGTATGAGCCGGGGCGCAGTCCGCTCTGGCATCGCGTTGTT
CAAGGAGAGTTGCAATGA

Upstream 100 bases:

>100_bases
GGTCTTTAGTCACAAAAAAATAACATTTCCCTGCGCTATTGTTGACTTTACCGGCGTTATGAAAATAAATGTCTATACAA
CCCATGACAAGTTAAGCGCT

Downstream 100 bases:

>100_bases
TGCTGTGGCAAGCTACGCCAGCCAGTCTCTGGCAGGGACGCGACGACAGCGCGGAAGCGCCCAATGCGCTGCGCCTGTTC
CAGACCATCGTCCGCGCGGA

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTEATSELVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGS
RAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQ
LADHNGVELSATLLSAHATPPEYQGDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVK
GHVEQLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNP
GTSPFASLHLAMNMACVKFGLTPEEAWAGVTRHAARALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVV
QGELQ

Sequences:

>Translated_405_residues
MTEATSELVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGS
RAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQ
LADHNGVELSATLLSAHATPPEYQGDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVK
GHVEQLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNP
GTSPFASLHLAMNMACVKFGLTPEEAWAGVTRHAARALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVV
QGELQ
>Mature_404_residues
TEATSELVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGSR
AQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQL
ADHNGVELSATLLSAHATPPEYQGDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKG
HVEQLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNPG
TSPFASLHLAMNMACVKFGLTPEEAWAGVTRHAARALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQ
GELQ

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=399, Percent_Identity=34.0852130325814, Blast_Score=188, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17555004, Length=369, Percent_Identity=33.0623306233062, Blast_Score=199, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 44156; Mature: 44025

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEATSELVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLE
CCCCCCCEEEEECCEEEECCCCCCCCCHHHHHCEEEEECCCEEEEEECCCCCCCCEEECC
GRLVTPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELL
CEEECCCCEECEEEEEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCEEECCCCCCHHHH
ALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATP
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
PEYQGDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVK
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCH
GHVEQLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKP
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHEECCCCCCC
PVELLRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPEEAWAGVTRHAARALGR
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
QASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ
CCCCCCCCCCHHHHEEEECCCCCHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
TEATSELVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLE
CCCCCCEEEEECCEEEECCCCCCCCCHHHHHCEEEEECCCEEEEEECCCCCCCCEEECC
GRLVTPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELL
CEEECCCCEECEEEEEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCEEECCCCCCHHHH
ALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATP
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
PEYQGDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVK
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCH
GHVEQLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKP
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHEECCCCCCC
PVELLRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPEEAWAGVTRHAARALGR
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
QASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ
CCCCCCCCCCHHHHEEEECCCCCHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA