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The map label for this gene is ybeM [H]

Identifier: 152969229

GI number: 152969229

Start: 746330

End: 747049

Strand: Direct

Name: ybeM [H]

Synonym: KPN_00658

Alternate gene names: 152969229

Gene position: 746330-747049 (Clockwise)

Preceding gene: 152969227

Following gene: 152969230

Centisome position: 14.04

GC content: 62.36

Gene sequence:

>720_bases
ATGATGCAGCAGGCGGAGCGAGAAGGGGCGGCACTGCTGGTGCTGCCGGAGGCGTTGCTGGCGCGGGATGACAACGACCC
GGATCTGTCAGTTAAATCGGCCCAGCCGCTGGATGGCGCATTTTTGCAGCCGCTGTTGGCCGAGAGCAGGCGTAACAGCC
TGACCACGGTCCTGACGCTCCATGTGCCGTCAGGGGAGGGGAGAGCGACCAACACGTTGGTGGTGTTACGGGAAGGCGCA
GTGATCGCCCATTATCACAAACTTCATCTATATGACGCCTTCGCGATGCAGGAGTCCCGGCGGGTGGATCCCGGTCAGCA
GATCCCGCCGGTGATTGAGGTGGCGGGATTACGCGTTGGCCTGATGACCTGCTACGATCTTCGCTTTCCGGAACTGGCGC
TTTCGTTGGCCCTGAATGGGGCACAGCTGCTGGTGCTGCCCGCTGCATGGGTGAAAGGGCCGCAGAAAGAGTATCACTGG
GCGACGCTGCTGGCGGCACGCGCTCTCGATACTACCTGCTATATCGTGGCGGCAGGCGAATGCGGAACGCGCAATATCGG
GCTGAGCCGCATCGTCGATCCGCTGGGGACCACTCTGGCGGGGGCCGGGAGCGAGCCGCAGCTGATCTTTGCCGATCTCT
CAGCGGATGACCTTGCGCGCGTTCGCGAGCGTTTGCCAGTGCTGCGGAACCGACGATTTGCGCCACCGCAATTATTATGA

Upstream 100 bases:

>100_bases
TTGGCTATCCATAACCTGACGGGAGAAGAACATGCGGGTAGCGGCAGGACAATTTGCCGTCACGCCAGTATGGCGGACGA
ATGCGCAAACCTGTGTGGCG

Downstream 100 bases:

>100_bases
CGTTTTTTTAAACAAGGCTTGATTCACCTTGTTACAGATTGCTATTGTGTCCGCGCGTCAAATACCCGTATTGTTTATCC
CAATAATTCGCTGTGCACGT

Product: NAD(P)-binding amidase-type enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPLDGAFLQPLLAESRRNSLTTVLTLHVPSGEGRATNTLVVLREGA
VIAHYHKLHLYDAFAMQESRRVDPGQQIPPVIEVAGLRVGLMTCYDLRFPELALSLALNGAQLLVLPAAWVKGPQKEYHW
ATLLAARALDTTCYIVAAGECGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADDLARVRERLPVLRNRRFAPPQLL

Sequences:

>Translated_239_residues
MMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPLDGAFLQPLLAESRRNSLTTVLTLHVPSGEGRATNTLVVLREGA
VIAHYHKLHLYDAFAMQESRRVDPGQQIPPVIEVAGLRVGLMTCYDLRFPELALSLALNGAQLLVLPAAWVKGPQKEYHW
ATLLAARALDTTCYIVAAGECGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADDLARVRERLPVLRNRRFAPPQLL
>Mature_239_residues
MMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPLDGAFLQPLLAESRRNSLTTVLTLHVPSGEGRATNTLVVLREGA
VIAHYHKLHLYDAFAMQESRRVDPGQQIPPVIEVAGLRVGLMTCYDLRFPELALSLALNGAQLLVLPAAWVKGPQKEYHW
ATLLAARALDTTCYIVAAGECGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADDLARVRERLPVLRNRRFAPPQLL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=252, Percent_Identity=36.1111111111111, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI297632350, Length=252, Percent_Identity=36.1111111111111, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI5031947, Length=252, Percent_Identity=36.1111111111111, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI9910460, Length=248, Percent_Identity=31.0483870967742, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI297632346, Length=175, Percent_Identity=34.2857142857143, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1786412, Length=171, Percent_Identity=29.2397660818713, Blast_Score=68, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=248, Percent_Identity=31.4516129032258, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322335, Length=227, Percent_Identity=32.15859030837, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323383, Length=179, Percent_Identity=31.2849162011173, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17933642, Length=244, Percent_Identity=30.7377049180328, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21355835, Length=209, Percent_Identity=27.7511961722488, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 25969; Mature: 25969

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPLDGAFLQPLLAESRRNSLTTVLTL
CCCCCCCCCCEEEEECHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEE
HVPSGEGRATNTLVVLREGAVIAHYHKLHLYDAFAMQESRRVDPGQQIPPVIEVAGLRVG
EECCCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEE
LMTCYDLRFPELALSLALNGAQLLVLPAAWVKGPQKEYHWATLLAARALDTTCYIVAAGE
EHHHCCCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCC
CGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADDLARVRERLPVLRNRRFAPPQLL
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHCHHHHCCCCCCCCCC
>Mature Secondary Structure
MMQQAEREGAALLVLPEALLARDDNDPDLSVKSAQPLDGAFLQPLLAESRRNSLTTVLTL
CCCCCCCCCCEEEEECHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEE
HVPSGEGRATNTLVVLREGAVIAHYHKLHLYDAFAMQESRRVDPGQQIPPVIEVAGLRVG
EECCCCCCCCEEEEEEECCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEE
LMTCYDLRFPELALSLALNGAQLLVLPAAWVKGPQKEYHWATLLAARALDTTCYIVAAGE
EHHHCCCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCC
CGTRNIGLSRIVDPLGTTLAGAGSEPQLIFADLSADDLARVRERLPVLRNRRFAPPQLL
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]