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The map label for this gene is mtnA [H]

Identifier: 152969198

GI number: 152969198

Start: 710325

End: 711353

Strand: Direct

Name: mtnA [H]

Synonym: KPN_00627

Alternate gene names: 152969198

Gene position: 710325-711353 (Clockwise)

Preceding gene: 152969196

Following gene: 152969205

Centisome position: 13.36

GC content: 65.89

Gene sequence:

>1029_bases
ATGCAGACATTACAGACCACCAGCCTGCGGGTGAGTGAAAATCAGCTTTTTATTCTCGACCAGCAGGCCTTGCCGCAGGA
AACACGCTGGCTGGCGGCGGATAACGTTGCGCTGCTGGTGGACCATATTCATACCCTGCGGGTGCGCGGCGCGCCGCTGA
TTGGCCTGTCAGCCAGCCTGCTGCTGGCTCTGCTGGCCCAGCGCGGCCTGAACCGGGATGCACTCCAGCAGGCGCTGGAG
ACGCTGCGCGCGGCGCGGCCGACGGCGGTCAACCTGATGAATAATCTGGATCGCATGAAGCAGGCGCTGGCCCGGGAGGA
TTACCCGCAGGCGCTGGAAGCGGAAGCCTTGCGTCTGGTCGAAGAAGATAAACAGCTGTGCGCCCGCATCGCTGAGGCGG
GCAGTGCGCTGGTGAAGCCCGGCAGTCGACTGCTGACCCACTGCAACACCGGTGGCCTGGCGACCGCCGGGGTAGGGACC
GCCCTGGGCGTTATCGCGCTGGCGCACCGGCAGGGAAAAGTGACCAACGTATGGGTTGATGAAACCCGGCCACTGCTGCA
GGGCGGTCGTTTAACCGCCTGGGAGCTGGGCGAGCTGGGCGTGCCCTATCAGCTGATCGCCGATTCAATGGCCGCCAGCC
TGATGGCGCAGGGGCAGGTGGATGCGGTGTGGGTCGGCGCCGACCGTATCGCCGCCAACGGCGACGTGGCGAATAAAATC
GGCACCTATTCTCTGGCGGTTTTGGCCCATTATCACCAGATCCCGTTTTACGTCGCGGCCCCGCAGACCACCCTCGACCG
CTATTGCCCGAACGGGGCGGCCATTCCCATTGAGCAGCGCGCCGCGGCCGAAGTGACCGGAGTGGCGGGCAGCTTTGGCG
CGGTACAGTGGGCGCCGACGGGGGCTGCCGTTTACAATCCGGCGTTCGACGTCACGCCTGCTGGGCTGATAAGCGGCTGG
GTGCTGGACAGCGGGGTGGTCACCCCGGCGCAGGTCGCCGCCGGGGCGTTTGCGCCGGACAACGGATAA

Upstream 100 bases:

>100_bases
GCCTCGATCCTCGAATTCTGATTAAGCCGTTCAGACGTCTATACTTCTGGATTCCATCCTGACACAATGTGATACAACAA
CGCAACAGGGATTTAACGAC

Downstream 100 bases:

>100_bases
CGGACGTCGTGCCGGGCCTGGAAAAAAAGGTTTTCCCGGGCCCGGACAAACACCGCGCCGCTACGGCAGGACCATGGCTA
CCGCCGGGGCGGATGATCGG

Product: methyltransferase domain-containing protein

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MQTLQTTSLRVSENQLFILDQQALPQETRWLAADNVALLVDHIHTLRVRGAPLIGLSASLLLALLAQRGLNRDALQQALE
TLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCARIAEAGSALVKPGSRLLTHCNTGGLATAGVGT
ALGVIALAHRQGKVTNVWVDETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPTGAAVYNPAFDVTPAGLISGW
VLDSGVVTPAQVAAGAFAPDNG

Sequences:

>Translated_342_residues
MQTLQTTSLRVSENQLFILDQQALPQETRWLAADNVALLVDHIHTLRVRGAPLIGLSASLLLALLAQRGLNRDALQQALE
TLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCARIAEAGSALVKPGSRLLTHCNTGGLATAGVGT
ALGVIALAHRQGKVTNVWVDETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPTGAAVYNPAFDVTPAGLISGW
VLDSGVVTPAQVAAGAFAPDNG
>Mature_342_residues
MQTLQTTSLRVSENQLFILDQQALPQETRWLAADNVALLVDHIHTLRVRGAPLIGLSASLLLALLAQRGLNRDALQQALE
TLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCARIAEAGSALVKPGSRLLTHCNTGGLATAGVGT
ALGVIALAHRQGKVTNVWVDETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPTGAAVYNPAFDVTPAGLISGW
VLDSGVVTPAQVAAGAFAPDNG

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=362, Percent_Identity=41.1602209944751, Blast_Score=224, Evalue=6e-59,
Organism=Homo sapiens, GI23943880, Length=341, Percent_Identity=38.7096774193548, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4503503, Length=206, Percent_Identity=30.5825242718447, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17557462, Length=331, Percent_Identity=42.5981873111783, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17557123, Length=234, Percent_Identity=27.3504273504274, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325375, Length=388, Percent_Identity=33.7628865979381, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322878, Length=273, Percent_Identity=27.1062271062271, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357667, Length=355, Percent_Identity=41.6901408450704, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24651647, Length=355, Percent_Identity=41.6901408450704, Blast_Score=222, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 36087; Mature: 36087

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLQTTSLRVSENQLFILDQQALPQETRWLAADNVALLVDHIHTLRVRGAPLIGLSASL
CCCCCCCEEEECCCEEEEEECCCCCHHHHEEECCCHHHHHHHHHHHHCCCCCEECHHHHH
LLALLAQRGLNRDALQQALETLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLV
HHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EEDKQLCARIAEAGSALVKPGSRLLTHCNTGGLATAGVGTALGVIALAHRQGKVTNVWVD
HHHHHHHHHHHHCCCHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
ETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
CCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHH
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPT
HHHHHHHHHHHHHCCEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCC
GAAVYNPAFDVTPAGLISGWVLDSGVVTPAQVAAGAFAPDNG
CCEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MQTLQTTSLRVSENQLFILDQQALPQETRWLAADNVALLVDHIHTLRVRGAPLIGLSASL
CCCCCCCEEEECCCEEEEEECCCCCHHHHEEECCCHHHHHHHHHHHHCCCCCEECHHHHH
LLALLAQRGLNRDALQQALETLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLV
HHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EEDKQLCARIAEAGSALVKPGSRLLTHCNTGGLATAGVGTALGVIALAHRQGKVTNVWVD
HHHHHHHHHHHHCCCHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
ETRPLLQGGRLTAWELGELGVPYQLIADSMAASLMAQGQVDAVWVGADRIAANGDVANKI
CCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHH
GTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPT
HHHHHHHHHHHHHCCEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCC
GAAVYNPAFDVTPAGLISGWVLDSGVVTPAQVAAGAFAPDNG
CCEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA