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The map label for this gene is thiL [H]

Identifier: 152968942

GI number: 152968942

Start: 408981

End: 409952

Strand: Direct

Name: thiL [H]

Synonym: KPN_00369

Alternate gene names: 152968942

Gene position: 408981-409952 (Clockwise)

Preceding gene: 152968941

Following gene: 152968943

Centisome position: 7.69

GC content: 61.21

Gene sequence:

>972_bases
ATGGCATGCGGCGAATTCTCCCTGATTGCCCGTTATTTTGATCGCGTTAAAAGCGCCCGCCTTGATGTTGAAACCGGCAT
CGGCGATGACTGCGCGCTCCTGCATATTCCCGAGAAAAAAACGCTGGCAATCAGCACCGACACCCTGGTGGCGGGCAATC
ACTTCTTACCCGATATCGACCCTGCCGACCTCGCTTATAAAGCGCTGGCGGTGAACCTGAGCGACCTCGCGGCGATGGGC
GCGGAGCCGGCGTGGCTCACGCTGGCGCTGACCTTGCCGGAGGTGGATGAAGTCTGGCTGGAAGCCTTCAGCGACAGCCT
GTTTGTCCAGCTGGACTATTACGATATGCAACTGATTGGCGGCGACACTACCCGTGGCCCGCTCTCCATGACGCTGGGTA
TCCACGGCTTTGTGCCGCCGGGACGCGCCATGAAACGCGCTGGCGCGAAGCCGGGGGACTGGATCTATGTTACCGGCACT
CCGGGAGATAGCGCCGCCGGTCTGGCTGTACTGCAGAATCGTCTAACGGTGGATGAACCGTCTGACGCCGACTACCTGCT
GGCCCGTCATCTGCGGCCGATGCCGCGCGTGCTGCAGGGCCAGGCGCTGCGTGACCTGGCGACATCGGCTATCGATCTTT
CCGACGGACTGATCTCCGATCTGGGCCATATTCTTAAAGCCAGCGGCTGCGGCGCACGTATCGATCTCGATGCCATGCCG
TACTCCGATGCGATGCTGCGCCAGGTTGATTCTGAGCAGGCGCTGCGCTGGGCGCTCGCCGGCGGGGAAGATTACGAGCT
GTGCTTTACCGTACCGGAGCTGAACCGCGGGGCGCTGGACGTGGCTCTTGGCCATCTTGGCGCGCGTTTTACCTGTATCG
GACAGATTGCGCCGGAGAGCGAAGGGCTGCAGTTTATCCGCGACGGTAAGCCGGTCGCGCTTGATTTAAAGGGATACGAT
CACTTTGCGTAG

Upstream 100 bases:

>100_bases
CTCCGGTAATTCGTCCCCACAAGAAGTAAACTGCAGGCCGGGTTTTGCGAGGGTCGCCTCGCAGCCCGGCCTTATTTATT
ATTTTGCTGAGGCATAACGT

Downstream 100 bases:

>100_bases
TCGAGACGAGGCGCTTAGCCGCCTGAGTATGCGTAATCCGTGGCATCTGCTGGCGACCGGCTTTGGTAGCGGCTTAAGCC
CGGTGGTGCCGGGTACGATG

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MACGEFSLIARYFDRVKSARLDVETGIGDDCALLHIPEKKTLAISTDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMG
AEPAWLTLALTLPEVDEVWLEAFSDSLFVQLDYYDMQLIGGDTTRGPLSMTLGIHGFVPPGRAMKRAGAKPGDWIYVTGT
PGDSAAGLAVLQNRLTVDEPSDADYLLARHLRPMPRVLQGQALRDLATSAIDLSDGLISDLGHILKASGCGARIDLDAMP
YSDAMLRQVDSEQALRWALAGGEDYELCFTVPELNRGALDVALGHLGARFTCIGQIAPESEGLQFIRDGKPVALDLKGYD
HFA

Sequences:

>Translated_323_residues
MACGEFSLIARYFDRVKSARLDVETGIGDDCALLHIPEKKTLAISTDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMG
AEPAWLTLALTLPEVDEVWLEAFSDSLFVQLDYYDMQLIGGDTTRGPLSMTLGIHGFVPPGRAMKRAGAKPGDWIYVTGT
PGDSAAGLAVLQNRLTVDEPSDADYLLARHLRPMPRVLQGQALRDLATSAIDLSDGLISDLGHILKASGCGARIDLDAMP
YSDAMLRQVDSEQALRWALAGGEDYELCFTVPELNRGALDVALGHLGARFTCIGQIAPESEGLQFIRDGKPVALDLKGYD
HFA
>Mature_322_residues
ACGEFSLIARYFDRVKSARLDVETGIGDDCALLHIPEKKTLAISTDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGA
EPAWLTLALTLPEVDEVWLEAFSDSLFVQLDYYDMQLIGGDTTRGPLSMTLGIHGFVPPGRAMKRAGAKPGDWIYVTGTP
GDSAAGLAVLQNRLTVDEPSDADYLLARHLRPMPRVLQGQALRDLATSAIDLSDGLISDLGHILKASGCGARIDLDAMPY
SDAMLRQVDSEQALRWALAGGEDYELCFTVPELNRGALDVALGHLGARFTCIGQIAPESEGLQFIRDGKPVALDLKGYDH
FA

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=323, Percent_Identity=84.5201238390093, Blast_Score=556, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34742; Mature: 34611

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACGEFSLIARYFDRVKSARLDVETGIGDDCALLHIPEKKTLAISTDTLVAGNHFLPDID
CCCCHHHHHHHHHHHHHHHCEEEECCCCCCEEEEECCCCCEEEEECCEEEECCCCCCCCC
PADLAYKALAVNLSDLAAMGAEPAWLTLALTLPEVDEVWLEAFSDSLFVQLDYYDMQLIG
HHHHHHHHHEECHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCCEEEEEEEEEEEEEC
GDTTRGPLSMTLGIHGFVPPGRAMKRAGAKPGDWIYVTGTPGDSAAGLAVLQNRLTVDEP
CCCCCCCEEEEEEEECCCCCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCC
SDADYLLARHLRPMPRVLQGQALRDLATSAIDLSDGLISDLGHILKASGCGARIDLDAMP
CCHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCC
YSDAMLRQVDSEQALRWALAGGEDYELCFTVPELNRGALDVALGHLGARFTCIGQIAPES
CCHHHHHHHCHHHHHEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEEEECCCCC
EGLQFIRDGKPVALDLKGYDHFA
CCCCEEECCCCEEEEECCCCCCC
>Mature Secondary Structure 
ACGEFSLIARYFDRVKSARLDVETGIGDDCALLHIPEKKTLAISTDTLVAGNHFLPDID
CCCHHHHHHHHHHHHHHHCEEEECCCCCCEEEEECCCCCEEEEECCEEEECCCCCCCCC
PADLAYKALAVNLSDLAAMGAEPAWLTLALTLPEVDEVWLEAFSDSLFVQLDYYDMQLIG
HHHHHHHHHEECHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCCEEEEEEEEEEEEEC
GDTTRGPLSMTLGIHGFVPPGRAMKRAGAKPGDWIYVTGTPGDSAAGLAVLQNRLTVDEP
CCCCCCCEEEEEEEECCCCCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCC
SDADYLLARHLRPMPRVLQGQALRDLATSAIDLSDGLISDLGHILKASGCGARIDLDAMP
CCHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCC
YSDAMLRQVDSEQALRWALAGGEDYELCFTVPELNRGALDVALGHLGARFTCIGQIAPES
CCHHHHHHHCHHHHHEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEEEECCCCC
EGLQFIRDGKPVALDLKGYDHFA
CCCCEEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]