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The map label for this gene is secD [H]

Identifier: 152968932

GI number: 152968932

Start: 400414

End: 402228

Strand: Direct

Name: secD [H]

Synonym: KPN_00359

Alternate gene names: 152968932

Gene position: 400414-402228 (Clockwise)

Preceding gene: 152968931

Following gene: 152968933

Centisome position: 7.53

GC content: 58.02

Gene sequence:

>1815_bases
ATGCTGGTCGTCGTCATTGTCGTCGGCCTGATCTATGCGCTTCCCAACCTGTATGGTGAGGATCCGGCTGTTCAAATCAC
TGGCGCGCGCGGCGTCGCCGCCAGTGAGCAAACGCTGATCCAGGTCCAGAAAACTTTACAAGAAGAAAAAATAACCGCGA
AGTCTGTGGCACTGGAAGAGGGCGCTATTCTTGCGCGCTTCGACACCACTGATACCCAGCTGCGCGCGCGCGAAGCGCTG
CTTAACGTGCTGGGTGACAAATACGTCGTGGCGCTGAACCTTGCTCCGGCAACCCCACGCTGGCTGGCGGCGCTCTATGC
CGAGCCGATGAAGCTGGGTCTTGATCTGCGCGGCGGCGTGCACTTCCTGATGGAAGTCGACATGGACACCGCGTTAGGCA
AACTGCAGGAACAGAACATCGATAGCCTGCGCAGCGAGCTGCGCGACAAAGGCATTCCTTACGCGACCGTGCGTAAAGAA
GACAACTACGGTCTGAGCATCGTCTTCCGCGACAGCGCGGCGCGCGACCAGGCTATCTCTTATCTCAGCCCTCGCCATCG
CGATCTGGTTATTTCCTCTCAGGGTGACAACAGCCTGAAAGCGGTGATGACCGATGAGCGCCTGAAAGAAGCCCGTGAGT
ACGCGGTTCAGCAGAACATTAATATCCTGCGTAACCGTGTGAACCAGCTGGGCGTCGCCGAGCCGCTGGTTCAGCGTCAG
GGCGCTGACCGCATCGTGGTTGAGCTGCCGGGTATCCAGGATACCGCGCGTGCGAAGGAAATCCTTGGCGCGACCGCGAC
CCTCGAGTTCCGTCTGGTCAATACTAACGTGGACCAGTCCGCCGCCGCCTCTGGCCGCGTGCCGGGCGACTCGGAAGTGA
AGCAGACGCGTGAAGGCCAGCCGGTAGTGCTGTACAAGCGGGTGATCCTGACCGGGGACCATATCACCGACTCGACCTCC
AGCATGGATGAGTACAACCAGCCGCAGGTCAACATCTCGCTGGACAGCGCGGGCGGTAACATCATGTCTAACTTCACTAA
GGACAACATCGGCAAGCCGATGGCGACCCTGTTCGTGGAGTATAAAGACAGCGGTAAGAAAGACGCTAACGGTCGCGCTA
TCCTGGCGAAAGAGGAAGAGGTGATTAACATCGCCAACATCCAGTCGCGTCTGGGTAACAGCTTCCGTATCACCGGTATC
AGCAATCCGAACGAAGCGCGTCAGCTGTCGCTGCTGCTGCGTGCCGGCGCGCTGATTGCGCCGATTCAGATCGTCGAAGA
GCGGACTATCGGCCCAACCCTGGGAATGCAGAACATCAAGCAGGGTTTGGAAGCCTGTCTGGCCGGTCTGGTGGTCTCTA
TCCTGTTCATGATCCTCTTCTATAAGAAGTTCGGCCTGATTGCGACCTCGGCGCTGATTGCCAACCTGATACTGATTGTC
GGCATTATGTCCCTGATCCCGGGGGCGACGCTGACCATGCCGGGCATCGCGGGTATCGTGTTAACCCTTGCGGTGGCGGT
CGATGCTAACGTTCTGATCAACGAGCGTATCAAAGAAGAGCTGAGCAACGGGCGTACCGTTCAGCAGGCGATTGACGAAG
GTTATCGCGGCGCGTTCAGCTCGATCTTCGACGCCAACGTGACGACGCTTATCAAAGTGATCATCCTGTACGCGGTCGGT
ACCGGTGCCATTAAAGGGTTTGCGATTACCACCGGTATCGGTATCGCGACCTCAATGTTTACCGCTATCGTCGGCACCCG
TGCCATCGTGAACCTGCTGTACGGCGGCAAGCGCGTTAAAAAGCTGTCTATCTGA

Upstream 100 bases:

>100_bases
TTGCTGCCGTTCTGCCGAAAGGCACCATGAAGGCGCTGTAATCTAACTTTTCCCAAAGGGAACTGCCGTGTTAAACCGTT
ATCCTTTGTGGAAGTACGTC

Downstream 100 bases:

>100_bases
GGAGTGCGTTGTGGCACAGGAATATACTGTTGAACAATTGAACCACGGCCGTAAAGTCTGGGACTTTATGCGCTGGGACT
ACTGGGCCTTCGGCATTTCA

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDTTDTQLRAREAL
LNVLGDKYVVALNLAPATPRWLAALYAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSELRDKGIPYATVRKE
DNYGLSIVFRDSAARDQAISYLSPRHRDLVISSQGDNSLKAVMTDERLKEAREYAVQQNINILRNRVNQLGVAEPLVQRQ
GADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTS
SMDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAILAKEEEVINIANIQSRLGNSFRITGI
SNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIATSALIANLILIV
GIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANVTTLIKVIILYAVG
TGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKRVKKLSI

Sequences:

>Translated_604_residues
MLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDTTDTQLRAREAL
LNVLGDKYVVALNLAPATPRWLAALYAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSELRDKGIPYATVRKE
DNYGLSIVFRDSAARDQAISYLSPRHRDLVISSQGDNSLKAVMTDERLKEAREYAVQQNINILRNRVNQLGVAEPLVQRQ
GADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTS
SMDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAILAKEEEVINIANIQSRLGNSFRITGI
SNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIATSALIANLILIV
GIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANVTTLIKVIILYAVG
TGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKRVKKLSI
>Mature_604_residues
MLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDTTDTQLRAREAL
LNVLGDKYVVALNLAPATPRWLAALYAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSELRDKGIPYATVRKE
DNYGLSIVFRDSAARDQAISYLSPRHRDLVISSQGDNSLKAVMTDERLKEAREYAVQQNINILRNRVNQLGVAEPLVQRQ
GADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTS
SMDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAILAKEEEVINIANIQSRLGNSFRITGI
SNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIATSALIANLILIV
GIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANVTTLIKVIILYAVG
TGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKRVKKLSI

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=604, Percent_Identity=93.2119205298013, Blast_Score=1146, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 65252; Mature: 65252

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEE
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GAILARFDTTDTQLRAREALLNVLGDKYVVALNLAPATPRWLAALYAEPMKLGLDLRGGV
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCE
HFLMEVDMDTALGKLQEQNIDSLRSELRDKGIPYATVRKEDNYGLSIVFRDSAARDQAIS
EEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHHH
YLSPRHRDLVISSQGDNSLKAVMTDERLKEAREYAVQQNINILRNRVNQLGVAEPLVQRQ
HCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
GADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPGDSEVKQTREGQ
CCCEEEEECCCCCHHHHHHHHHCCEEEEEEEEEECCCCCHHHCCCCCCCCHHHHHHCCCC
PVVLYKRVILTGDHITDSTSSMDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVE
CEEEEEEEEEECCCCCCCCCCHHHCCCCEEEEEEECCCCHHHHCCCHHCCCCCHHHEEEE
YKDSGKKDANGRAILAKEEEVINIANIQSRLGNSFRITGISNPNEARQLSLLLRAGALIA
ECCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCHHH
PIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIATSALIANLILIV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFS
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SIFDANVTTLIKVIILYAVGTGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKRVK
HHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
KLSI
ECCC
>Mature Secondary Structure
MLVVVIVVGLIYALPNLYGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEE
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GAILARFDTTDTQLRAREALLNVLGDKYVVALNLAPATPRWLAALYAEPMKLGLDLRGGV
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCE
HFLMEVDMDTALGKLQEQNIDSLRSELRDKGIPYATVRKEDNYGLSIVFRDSAARDQAIS
EEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHHH
YLSPRHRDLVISSQGDNSLKAVMTDERLKEAREYAVQQNINILRNRVNQLGVAEPLVQRQ
HCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
GADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQSAAASGRVPGDSEVKQTREGQ
CCCEEEEECCCCCHHHHHHHHHCCEEEEEEEEEECCCCCHHHCCCCCCCCHHHHHHCCCC
PVVLYKRVILTGDHITDSTSSMDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVE
CEEEEEEEEEECCCCCCCCCCHHHCCCCEEEEEEECCCCHHHHCCCHHCCCCCHHHEEEE
YKDSGKKDANGRAILAKEEEVINIANIQSRLGNSFRITGISNPNEARQLSLLLRAGALIA
ECCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCHHH
PIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMILFYKKFGLIATSALIANLILIV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFS
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SIFDANVTTLIKVIILYAVGTGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKRVK
HHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
KLSI
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]