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The map label for this gene is crl [H]

Identifier: 152968826

GI number: 152968826

Start: 284460

End: 284858

Strand: Direct

Name: crl [H]

Synonym: KPN_00252

Alternate gene names: 152968826

Gene position: 284460-284858 (Clockwise)

Preceding gene: 152968825

Following gene: 152968833

Centisome position: 5.35

GC content: 53.88

Gene sequence:

>399_bases
ATGACGTTACCGAGTGGACACCTGAAAAGTAAGTTGATCAAGAAATTCACGGCGCTGGGGCCTTACATTCGCGAAGAGCA
GTGCCATGACAACCGTTTCTTTTTCGATTGCCTGGCAGTTTGCGTCAATGTTAAGCCCGCACCGGAGAAGCGTGAATTCT
GGGGCTGGTGGATGGAAATGGAAGCACAAGAGTCACGTTTCACCTATAGCTACCAGTTTGGCCTGTTCAATAAGGAAGGA
TCATGGCAGGCGGTCGACATTGACGACCCGGAAGTGAGCGACAGGCTGGAAAAAACGCTGCGCGAGTTTCACGAGCGCGC
AGCAGCGCTGCTGACCACCTTTAATCTGAAGCTGGAACCGGCCGACGATTTCAGCGAGCCGGTTCGCCTGCGAGCCTGA

Upstream 100 bases:

>100_bases
ATTGCGACAGATCGCCCGCTGGATCAATCATAGATTTGGTTAATTTATTGCTAAATTCTATTGGTTTGGTAAAACAGTTG
CATCACTAAAGGAGATCGCA

Downstream 100 bases:

>100_bases
TTGATCTACGGATACGATTTCTCCACGCCCGTGCGGCGTGGAGATGCGTGCCGCCGTACCCGTAATTTCCACCCCTCCAT
CTGACTCACCCTGCCTGCGG

Product: DNA-binding transcriptional regulator Crl

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MTLPSGHLKSKLIKKFTALGPYIREEQCHDNRFFFDCLAVCVNVKPAPEKREFWGWWMEMEAQESRFTYSYQFGLFNKEG
SWQAVDIDDPEVSDRLEKTLREFHERAAALLTTFNLKLEPADDFSEPVRLRA

Sequences:

>Translated_132_residues
MTLPSGHLKSKLIKKFTALGPYIREEQCHDNRFFFDCLAVCVNVKPAPEKREFWGWWMEMEAQESRFTYSYQFGLFNKEG
SWQAVDIDDPEVSDRLEKTLREFHERAAALLTTFNLKLEPADDFSEPVRLRA
>Mature_131_residues
TLPSGHLKSKLIKKFTALGPYIREEQCHDNRFFFDCLAVCVNVKPAPEKREFWGWWMEMEAQESRFTYSYQFGLFNKEGS
WQAVDIDDPEVSDRLEKTLREFHERAAALLTTFNLKLEPADDFSEPVRLRA

Specific function: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the crl family [H]

Homologues:

Organism=Escherichia coli, GI1786435, Length=133, Percent_Identity=78.9473684210526, Blast_Score=219, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009986 [H]

Pfam domain/function: PF07417 Crl [H]

EC number: NA

Molecular weight: Translated: 15540; Mature: 15409

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPSGHLKSKLIKKFTALGPYIREEQCHDNRFFFDCLAVCVNVKPAPEKREFWGWWMEM
CCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHE
EAQESRFTYSYQFGLFNKEGSWQAVDIDDPEVSDRLEKTLREFHERAAALLTTFNLKLEP
ECCCCEEEEEEEECEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECC
ADDFSEPVRLRA
CCCCCCCEECCC
>Mature Secondary Structure 
TLPSGHLKSKLIKKFTALGPYIREEQCHDNRFFFDCLAVCVNVKPAPEKREFWGWWMEM
CCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHE
EAQESRFTYSYQFGLFNKEGSWQAVDIDDPEVSDRLEKTLREFHERAAALLTTFNLKLEP
ECCCCEEEEEEEECEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECC
ADDFSEPVRLRA
CCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA