| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is secA [H]
Identifier: 152968683
GI number: 152968683
Start: 120125
End: 122830
Strand: Direct
Name: secA [H]
Synonym: KPN_00102
Alternate gene names: 152968683
Gene position: 120125-122830 (Clockwise)
Preceding gene: 152968682
Following gene: 152968684
Centisome position: 2.26
GC content: 56.47
Gene sequence:
>2706_bases ATGCTTATCAAAATGTTAACCAAGGTTTTCGGCAGCCGTAACGACCGTACGCTGCGTCGTATGCGCAAAGTCGTCAATAT CATCAACGGCATGGAACCGGCGATGGAAAAACTCTCTGATGACGAGCTGAAAGCGAAAACCGCTGAATTCCGCGCGCGCC TGGAAAAAGGCGAAACGCTGGAAAGCCTGATCCCTGAAGCTTTCGCCGTCGTTCGCGAAGCCAGTAAGCGCGTATTCGGC ATGCGCCACTTCGACGTCCAGCTGCTGGGCGGTATGGTGCTTAACGATCGCTGCATCGCCGAGATGCGTACCGGTGAAGG TAAAACCCTGACCGCGACCCTGCCGGCGTACCTCAACGCGCTAACCGGCAAAGGCGTTCACGTAGTGACCGTCAACGACT ATCTGGCCCAGCGTGACGCCGAAAATAACCGCCCGCTGTTTGAATTCCTGGGCATGACAGTTGGCATCAACATGTCCGGC CTGCCGGCGCCGGCGAAGCGTGAAGCTTACGCTGCCGATATCACCTATGGCACCAACAACGAATACGGCTTCGACTACCT GCGCGACAACATGGCCTTCAGCCCGGAAGAGCGCGTTCAGCGTAAATTGCACTATGCGCTGGTGGATGAGGTGGATTCCA TCCTGATCGATGAGGCGCGTACGCCGCTGATCATTTCCGGCCCGGCGGAAGACAGCTCTGAAATGTACCGCAAGGTAAAC AAAATCATCCCGCATCTGATCCGCCAGGAAAAAGAGGATTCGGATACTTTCACTGGCGAAGGCCACTTCTCGGTGGATGA AAAAGCGCGTCAGGTTAACCTGACCGAACGTGGTCTGGTGCTGATTGAAGAGCTGCTGGTACAGGAAGGCATTATGGATG AAGGTGAGTCCCTGTACTCTCCAACCAACATTATGCTGATGCACCACGTTACCGCCGCGCTGCGCGCCCATGCGCTGTTC ACCCGCGACGTTGACTACATTGTCAAAGATGGCGAAGTTATCATCGTCGATGAGCACACTGGCCGTACGATGCAGGGCCG CCGCTGGTCCGATGGTCTGCACCAGGCCGTTGAGGCCAAAGAGGGCGTGGAGATCCAAAACGAGAACCAGACTCTGGCCT CTATCACCTTCCAGAACTACTTCCGTCTGTACGAGAAGCTGGCGGGGATGACCGGTACAGCCGATACCGAAGCCTTTGAA TTCAGCTCTATCTATAAGCTGGATACCGTGGTTGTACCGACCAACCGTCCGATGATCCGTAAAGACATGGCGGATCTGGT CTATATGACCGAAGCGGAAAAAATTCAGGCAATTATCGAAGATATCAAAACTCGTACCGCTGCCGGTCAGCCGGTGCTGG TGGGGACTATCTCGATCGAAAAATCTGAAGTGGTTTCCCGCGAACTGACTAAAGCCGGCATCAAGCACAACGTCCTGAAC GCCAAATTCCACGCCAGCGAGGCGGATATCGTCGCCCAGGCGGGCTACCCTTCCGCGGTGACCATCGCCACCAACATGGC GGGTCGTGGTACCGATATTATGCTCGGCGGTAGCTGGCAGGCGGAAGTCGCTGCGCTGGAAAACCCAACGCCAGAGCAGA TTGAGAAAATCAAAGCCGACTGGCAGGTACGCCACGATGCGGTACTGGCCGCAGGCGGTCTGCACATCATCGGTACCGAG CGTCATGAATCTCGCCGTATCGATAACCAGCTGCGCGGCCGTGCTGGTCGTCAAGGGGATGCAGGTTCTTCCCGCTTCTA CCTGTCAATGGAAGATGCCCTGATGCGTATCTTCGCCTCCGATCGCGTGTCTGGCATGATGCGTAAACTGGGAATGAAAC CTGGTGAGGCGATTGAGCACCCGTGGGTCACCAAGGCGATCGCCAACGCCCAGCGTAAAGTGGAAAGCCGTAACTTCGAT ATCCGTAAGCAGCTGCTGGAATATGATGATGTGGCCAACGACCAGCGCCGGGCGATCTACACCCAGCGTAACGAGCTGCT GGACGTGTCTGACGTCAGCGAAACCATCAACAGCATCCGCGAAGACGTCTTTAAGGCGACGATCGATGCCCATATTCCGC CGCAGTCGCTGGAGGAGATGTGGGATATCGAAGGTCTGCAGGAGCGTCTGAAAAACGACTTCGACCTCGACCTACCAATC AAAGAGTGGCTGGATAAAGAGCCGGAGCTGCATGAAGAGACCCTGCGCGAACGTATTCTGCAGAGCGCGGTAGAAACCTA CCAGCGTAAAGAAGAAGTGGTCGGCGCCGAGATGATGCGCCACTTCGAGAAAGGCGTGATGCTGCAGACTCTGGATTCGC TGTGGAAAGAGCACCTGGCGGCGATGGATTACCTGCGCCAGGGTATCCACCTGCGCGGCTATGCGCAGAAAGATCCGAAG CAGGAGTACAAGCGCGAATCGTTCTCAATGTTTGCCGCGATGCTGGAGTCACTGAAGTATGAAGTGATCAGCACCCTGAG CAAAGTCCAGGTGCGGATGCCGGAAGAAGTCGAGGCGATGGAACAGCAGCGTCGTGAAGAGGCCGAGCGCCTGGCGCAGA TGCAGCAGCTCAGCCATCAGAGCGATGATGAAGCCGCAGCCCAGGATCTGGCGGCGCAAACCGGCGAACGTAAAGTGGGC CGTAACGATCCGTGCCCGTGCGGCTCCGGCAAAAAGTACAAACAGTGCCACGGCCGTCTGAGCTAA
Upstream 100 bases:
>100_bases TGGCGGGGATCCGCGCAGGGCCTCAACGTCTCAGCTGAAAATAACCACGGACCATCCTATTTTTTGTGACTCCGCACCGC GGGGCGTTTGAGATTTTATT
Downstream 100 bases:
>100_bases GGTCTGATAAAACAAACAAAGGCGCAGAGTTCTGCGCCTTTTTTATGGAGCGCATTCAATGAAAAAACTGCAAATCGCCG TCGGGATAATTCGCAATCCG
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 901; Mature: 901
Protein sequence:
>901_residues MLIKMLTKVFGSRNDRTLRRMRKVVNIINGMEPAMEKLSDDELKAKTAEFRARLEKGETLESLIPEAFAVVREASKRVFG MRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGMTVGINMSG LPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYRKVN KIIPHLIRQEKEDSDTFTGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPTNIMLMHHVTAALRAHALF TRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFE FSSIYKLDTVVVPTNRPMIRKDMADLVYMTEAEKIQAIIEDIKTRTAAGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN AKFHASEADIVAQAGYPSAVTIATNMAGRGTDIMLGGSWQAEVAALENPTPEQIEKIKADWQVRHDAVLAAGGLHIIGTE RHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFD IRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSETINSIREDVFKATIDAHIPPQSLEEMWDIEGLQERLKNDFDLDLPI KEWLDKEPELHEETLRERILQSAVETYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPK QEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEQQRREEAERLAQMQQLSHQSDDEAAAQDLAAQTGERKVG RNDPCPCGSGKKYKQCHGRLS
Sequences:
>Translated_901_residues MLIKMLTKVFGSRNDRTLRRMRKVVNIINGMEPAMEKLSDDELKAKTAEFRARLEKGETLESLIPEAFAVVREASKRVFG MRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGMTVGINMSG LPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYRKVN KIIPHLIRQEKEDSDTFTGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPTNIMLMHHVTAALRAHALF TRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFE FSSIYKLDTVVVPTNRPMIRKDMADLVYMTEAEKIQAIIEDIKTRTAAGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN AKFHASEADIVAQAGYPSAVTIATNMAGRGTDIMLGGSWQAEVAALENPTPEQIEKIKADWQVRHDAVLAAGGLHIIGTE RHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFD IRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSETINSIREDVFKATIDAHIPPQSLEEMWDIEGLQERLKNDFDLDLPI KEWLDKEPELHEETLRERILQSAVETYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPK QEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEQQRREEAERLAQMQQLSHQSDDEAAAQDLAAQTGERKVG RNDPCPCGSGKKYKQCHGRLS >Mature_901_residues MLIKMLTKVFGSRNDRTLRRMRKVVNIINGMEPAMEKLSDDELKAKTAEFRARLEKGETLESLIPEAFAVVREASKRVFG MRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGMTVGINMSG LPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYRKVN KIIPHLIRQEKEDSDTFTGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPTNIMLMHHVTAALRAHALF TRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFE FSSIYKLDTVVVPTNRPMIRKDMADLVYMTEAEKIQAIIEDIKTRTAAGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN AKFHASEADIVAQAGYPSAVTIATNMAGRGTDIMLGGSWQAEVAALENPTPEQIEKIKADWQVRHDAVLAAGGLHIIGTE RHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFD IRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSETINSIREDVFKATIDAHIPPQSLEEMWDIEGLQERLKNDFDLDLPI KEWLDKEPELHEETLRERILQSAVETYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPK QEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEQQRREEAERLAQMQQLSHQSDDEAAAQDLAAQTGERKVG RNDPCPCGSGKKYKQCHGRLS
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=900, Percent_Identity=94.5555555555556, Blast_Score=1763, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 101962; Mature: 101962
Theoretical pI: Translated: 5.31; Mature: 5.31
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLIKMLTKVFGSRNDRTLRRMRKVVNIINGMEPAMEKLSDDELKAKTAEFRARLEKGETL CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCHH ESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNA HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHH LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGMTVGINMSGLPAPAKREAYAADITYGTNN HCCCCEEEEEECHHHHHCCCCCCCCHHHHHCHHHCCCCCCCCCCCCCCCEEEEEEECCCC EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYRKVN CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH KIIPHLIRQEKEDSDTFTGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYS HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCC PTNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK CHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHH EGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR CCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEEEECCCCCHHH KDMADLVYMTEAEKIQAIIEDIKTRTAAGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCC AKFHASEADIVAQAGYPSAVTIATNMAGRGTDIMLGGSWQAEVAALENPTPEQIEKIKAD CEECCCCCCEEEECCCCCEEEEEECCCCCCCEEEECCCCCHHHHCCCCCCHHHHHHHHHH WQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFAS HHHHHHHEEEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHH DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHH TQRNELLDVSDVSETINSIREDVFKATIDAHIPPQSLEEMWDIEGLQERLKNDFDLDLPI HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH KEWLDKEPELHEETLRERILQSAVETYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEAM HHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH EQQRREEAERLAQMQQLSHQSDDEAAAQDLAAQTGERKVGRNDPCPCGSGKKYKQCHGRL HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCC S C >Mature Secondary Structure MLIKMLTKVFGSRNDRTLRRMRKVVNIINGMEPAMEKLSDDELKAKTAEFRARLEKGETL CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCHH ESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNA HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHH LTGKGVHVVTVNDYLAQRDAENNRPLFEFLGMTVGINMSGLPAPAKREAYAADITYGTNN HCCCCEEEEEECHHHHHCCCCCCCCHHHHHCHHHCCCCCCCCCCCCCCCEEEEEEECCCC EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYRKVN CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH KIIPHLIRQEKEDSDTFTGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYS HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCC PTNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK CHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHH EGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR CCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEEEECCCCCHHH KDMADLVYMTEAEKIQAIIEDIKTRTAAGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCC AKFHASEADIVAQAGYPSAVTIATNMAGRGTDIMLGGSWQAEVAALENPTPEQIEKIKAD CEECCCCCCEEEECCCCCEEEEEECCCCCCCEEEECCCCCHHHHCCCCCCHHHHHHHHHH WQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDALMRIFAS HHHHHHHEEEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHH DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHH TQRNELLDVSDVSETINSIREDVFKATIDAHIPPQSLEEMWDIEGLQERLKNDFDLDLPI HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH KEWLDKEPELHEETLRERILQSAVETYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH AMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEAM HHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH EQQRREEAERLAQMQQLSHQSDDEAAAQDLAAQTGERKVGRNDPCPCGSGKKYKQCHGRL HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCC S C
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA