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The map label for this gene is citC2

Identifier: 152968615

GI number: 152968615

Start: 36163

End: 37191

Strand: Direct

Name: citC2

Synonym: KPN_00034

Alternate gene names: 152968615

Gene position: 36163-37191 (Clockwise)

Preceding gene: 152968606

Following gene: 152968616

Centisome position: 0.68

GC content: 58.11

Gene sequence:

>1029_bases
ATGACACTGATATTAAAACGCGTTCAGCTATTAAAAGATAAACCGCGGCGAGAGGCGATCGATCGGTTTCTCCGCCAGCA
TCAACTGTCGTTAGAGGCCGACTGCGAAATGGCGATTATCGCCGAGTATCAGCAGCGGCTGGTCGGCTGCGGTGCTATCG
CCGGCAATGTGCTGAAATGCATCGCCATCGATCCCTCGCTGCAGGGGGAGGGGCTGAGCCTTAAATTACTGACCGAGCTC
CTGACGCTGGCCTATGAGCTGGGGCGCAGCGAACTGTTTTTGTTCACTAAACCTTGCAATGCCGCGTTATTTTCCGGCGC
CGGCTTCTGGCCGATAGCCCAGGCGGGCGACCGCGCCGTGCTAATGGAAAATAGCCGCGAACGGCTGACTCGTTACTGTC
GACAGCTGGCGATGTACCGTCAGCCGGGAAGAAAAATCGGCGCTATCGTGATGAATGCCAATCCCTTCACCCTCGGCCAC
CGCTGGTTGGTAGAACAGGCGGCCAGCCAGTGCGACTGGCTGCATCTGTTTGTGGTCAAAGAAGATGCGTCCTGCTTTTC
CTATCACGATCGCTTCAAGCTCATTGAACAGGGGATTACCGGCATCGATAAGGTGACGCTGCATCCCGGTTCGGCGTATC
TGATCTCGCGGGCGACGTTCCCCGGCTATTTCCTGAAAGAGCAGGGGGTGGTTGATGACTGCCACAGCCAGATTGACCTG
CAGCTCTTCCGCGAGCGCCTGGCCCCGGCGCTGCAGATTACCCATCGCTTTGTCGGCACCGAGCCGCTGTGTCCCCTGAC
CCGTAATTACAACCAGCGCATGAAGTCACTACTGGAAGCGCCAGGCGACGCGCCGCCCATTGAAGTAGTTGAGCTTGCGC
GAATCGAAAAAAATGGTGGACCCGTGTCGGCCTCCCGAGTGCGCGAACTCTATCGACAGCGCAACTGGCAGGCGGTCGCG
GCGCTGGTACCGCCGGGAACCCTCTCTTTTCTGATGCAACTGGCGGAAAGCGAACATCAAACCGCCTGA

Upstream 100 bases:

>100_bases
AGCCAATTAAGCCACGAGAAAAACTGTGACTTAAATACAAGAATCCATAGCCGAACGCTGGCGAAATACAGTTCGTTTTG
AAATGACGAAGCGCTAAAAA

Downstream 100 bases:

>100_bases
TTTATACGCCCTAACTAAGGATTTTCCCCTATGGAAATGAAGATTGACGCCCTGGCCGGCACGCTGGAGTCCAGCGATGT
GATGGTCAGGATTGGACCCG

Product: putative citrate lyase synthetase (citrate (pro-3S)-lyase ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTLILKRVQLLKDKPRREAIDRFLRQHQLSLEADCEMAIIAEYQQRLVGCGAIAGNVLKCIAIDPSLQGEGLSLKLLTEL
LTLAYELGRSELFLFTKPCNAALFSGAGFWPIAQAGDRAVLMENSRERLTRYCRQLAMYRQPGRKIGAIVMNANPFTLGH
RWLVEQAASQCDWLHLFVVKEDASCFSYHDRFKLIEQGITGIDKVTLHPGSAYLISRATFPGYFLKEQGVVDDCHSQIDL
QLFRERLAPALQITHRFVGTEPLCPLTRNYNQRMKSLLEAPGDAPPIEVVELARIEKNGGPVSASRVRELYRQRNWQAVA
ALVPPGTLSFLMQLAESEHQTA

Sequences:

>Translated_342_residues
MTLILKRVQLLKDKPRREAIDRFLRQHQLSLEADCEMAIIAEYQQRLVGCGAIAGNVLKCIAIDPSLQGEGLSLKLLTEL
LTLAYELGRSELFLFTKPCNAALFSGAGFWPIAQAGDRAVLMENSRERLTRYCRQLAMYRQPGRKIGAIVMNANPFTLGH
RWLVEQAASQCDWLHLFVVKEDASCFSYHDRFKLIEQGITGIDKVTLHPGSAYLISRATFPGYFLKEQGVVDDCHSQIDL
QLFRERLAPALQITHRFVGTEPLCPLTRNYNQRMKSLLEAPGDAPPIEVVELARIEKNGGPVSASRVRELYRQRNWQAVA
ALVPPGTLSFLMQLAESEHQTA
>Mature_341_residues
TLILKRVQLLKDKPRREAIDRFLRQHQLSLEADCEMAIIAEYQQRLVGCGAIAGNVLKCIAIDPSLQGEGLSLKLLTELL
TLAYELGRSELFLFTKPCNAALFSGAGFWPIAQAGDRAVLMENSRERLTRYCRQLAMYRQPGRKIGAIVMNANPFTLGHR
WLVEQAASQCDWLHLFVVKEDASCFSYHDRFKLIEQGITGIDKVTLHPGSAYLISRATFPGYFLKEQGVVDDCHSQIDLQ
LFRERLAPALQITHRFVGTEPLCPLTRNYNQRMKSLLEAPGDAPPIEVVELARIEKNGGPVSASRVRELYRQRNWQAVAA
LVPPGTLSFLMQLAESEHQTA

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI87081765, Length=340, Percent_Identity=51.1764705882353, Blast_Score=353, Evalue=1e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CITC_KLEPN (P45410)

Other databases:

- EMBL:   X79817
- PIR:   S60773
- ProteinModelPortal:   P45410
- BRENDA:   6.2.1.22
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.630.30
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF005751
- SMART:   SM00764
- TIGRFAMs:   TIGR00124
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF08218 Citrate_ly_lig; SSF55729 Acyl_CoA_acyltransferase

EC number: =6.2.1.22

Molecular weight: Translated: 38477; Mature: 38346

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLILKRVQLLKDKPRREAIDRFLRQHQLSLEADCEMAIIAEYQQRLVGCGAIAGNVLKC
CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
IAIDPSLQGEGLSLKLLTELLTLAYELGRSELFLFTKPCNAALFSGAGFWPIAQAGDRAV
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCCCCCCCHHCCCCEEE
LMENSRERLTRYCRQLAMYRQPGRKIGAIVMNANPFTLGHRWLVEQAASQCDWLHLFVVK
EECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEE
EDASCFSYHDRFKLIEQGITGIDKVTLHPGSAYLISRATFPGYFLKEQGVVDDCHSQIDL
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCHHCCCCCHHHHHHHHHH
QLFRERLAPALQITHRFVGTEPLCPLTRNYNQRMKSLLEAPGDAPPIEVVELARIEKNGG
HHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
PVSASRVRELYRQRNWQAVAALVPPGTLSFLMQLAESEHQTA
CCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLILKRVQLLKDKPRREAIDRFLRQHQLSLEADCEMAIIAEYQQRLVGCGAIAGNVLKC
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
IAIDPSLQGEGLSLKLLTELLTLAYELGRSELFLFTKPCNAALFSGAGFWPIAQAGDRAV
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCCCCCCCHHCCCCEEE
LMENSRERLTRYCRQLAMYRQPGRKIGAIVMNANPFTLGHRWLVEQAASQCDWLHLFVVK
EECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEE
EDASCFSYHDRFKLIEQGITGIDKVTLHPGSAYLISRATFPGYFLKEQGVVDDCHSQIDL
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCHHCCCCCHHHHHHHHHH
QLFRERLAPALQITHRFVGTEPLCPLTRNYNQRMKSLLEAPGDAPPIEVVELARIEKNGG
HHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
PVSASRVRELYRQRNWQAVAALVPPGTLSFLMQLAESEHQTA
CCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7830578