Click here to switch to the map view.

The map label for this gene is nudG [H]

Identifier: 151222599

GI number: 151222599

Start: 2622622

End: 2623014

Strand: Reverse

Name: nudG [H]

Synonym: NWMN_2387

Alternate gene names: 151222599

Gene position: 2623014-2622622 (Counterclockwise)

Preceding gene: 151222603

Following gene: 151222598

Centisome position: 91.11

GC content: 31.55

Gene sequence:

>393_bases
ATGAAAAAAGTAATCAATGTAGTAGGAGCTATTATTTTTTCTGATAACAAAATTCTTTGTGCACAGAGAAGTGAAAAAAT
GAGTCTGCCTTTAATGTGGGAATTTCCTGGCGGTAAGGTTGAAAAGAATGAAACTGAAAAAGACGCTTTGATTAGAGAAA
TTAGAGAAGAAATGAAATGTGATTTAATTGTTGGAGACAAAGTTATAACTACAGAACATGAATATGATTTTGGAATTGTT
AGGTTAACAACATACAAATGTACTTTAAACAAAGAGTTACCAACTCTAACTGAACATAAGAGTATTGAATGGTTGTCAAT
AAACGAACTTGATAAATTAAATTGGGCCCCAGCGGATATACCAGCCGTTAATAAAATTATGACTGAGGGATAA

Upstream 100 bases:

>100_bases
GTGAATGTAAAATATTAATTTTTAATATTGATTTATATATAGTTTTGTAATTTTTGATAGAATAACAATTAAGATGATTT
TAAATTGAAGGGTGAGTCTT

Downstream 100 bases:

>100_bases
TATGAGTAGATTACTAAATGATTTCAATCAATCTTTACATAAAGGGTTTATAGACAAACATATTTCTCATAAAGGGAATT
ATACACCGAAGCTTTTAGTA

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MKKVINVVGAIIFSDNKILCAQRSEKMSLPLMWEFPGGKVEKNETEKDALIREIREEMKCDLIVGDKVITTEHEYDFGIV
RLTTYKCTLNKELPTLTEHKSIEWLSINELDKLNWAPADIPAVNKIMTEG

Sequences:

>Translated_130_residues
MKKVINVVGAIIFSDNKILCAQRSEKMSLPLMWEFPGGKVEKNETEKDALIREIREEMKCDLIVGDKVITTEHEYDFGIV
RLTTYKCTLNKELPTLTEHKSIEWLSINELDKLNWAPADIPAVNKIMTEG
>Mature_130_residues
MKKVINVVGAIIFSDNKILCAQRSEKMSLPLMWEFPGGKVEKNETEKDALIREIREEMKCDLIVGDKVITTEHEYDFGIV
RLTTYKCTLNKELPTLTEHKSIEWLSINELDKLNWAPADIPAVNKIMTEG

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=126, Percent_Identity=38.0952380952381, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14895; Mature: 14895

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVINVVGAIIFSDNKILCAQRSEKMSLPLMWEFPGGKVEKNETEKDALIREIREEMKC
CHHHHHHHEEEEECCCEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCC
DLIVGDKVITTEHEYDFGIVRLTTYKCTLNKELPTLTEHKSIEWLSINELDKLNWAPADI
EEEECCEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
PAVNKIMTEG
CHHHHHHCCC
>Mature Secondary Structure
MKKVINVVGAIIFSDNKILCAQRSEKMSLPLMWEFPGGKVEKNETEKDALIREIREEMKC
CHHHHHHHEEEEECCCEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCC
DLIVGDKVITTEHEYDFGIVRLTTYKCTLNKELPTLTEHKSIEWLSINELDKLNWAPADI
EEEECCEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
PAVNKIMTEG
CHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]