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The map label for this gene is ydbM [H]

Identifier: 151222398

GI number: 151222398

Start: 2407441

End: 2408376

Strand: Reverse

Name: ydbM [H]

Synonym: NWMN_2186

Alternate gene names: 151222398

Gene position: 2408376-2407441 (Counterclockwise)

Preceding gene: 151222399

Following gene: 151222397

Centisome position: 83.66

GC content: 35.79

Gene sequence:

>936_bases
ATGGTTATTTTGCAATCATTTTTAGGCGAACTTGATGGTGCCACAGCATTATCTATTGGTTGGCATGTGAGTGTCGTAGG
ACAAATTTATGAACAGAAATTATGGTCTCAAGATATGTTGGAGCAATTTGCTGTTGAAATTAATAATGGTGCATTAGTTA
ATAGAGCAGTTAGTGAAGCTGAAATGGGTAGTCCAACAAGAGGGGGAAGACCAAGTACACATGCTGTTAAAGCTGATGAT
GGGTATATTTTAAATGGTGTGAAGACATATACATCAATGAGTAAAGCACTAACACATATTATTGTTGCTGCTTATATAGA
AGAATTAGAAAGTGTTGGTTTTTTCTTAGTAGACAGGAATTTGCCTGGTGTTGAAATTGCCGATAATTGGGACGTATTAG
GTATGCGAGCGACAGAAAGTCATGATTTAATATTAAATGATGTAAAAGTACCATTAAAACATTTAGTGGAAACAGAGAAA
AGTAAAGCGCCAAATGGTTGGATATTGCATATACCAAGCTGTTATTTAGGTATAGCACAAGCTGCTAGAAATTATGCTGT
AGACTTTGCAATCCAACATAGCCCTAATAGTATTGAAGGAACGATTGCAACATTGCCAACTGTGCAACAAAATTTAGGGA
AAATGGAAACGCTATTGTTATGTGCGAGACAATTTTTATGGAGTACAGCAAAAGGGTATCAACAATATAAAGATGACAGT
CAGATAAGAAATCCAACAAGTGCGAGTAAAGTGATGGTAATGAATCAAGGGCTTGAAGTGATTGATTTAGCGATGAGAAT
AGTTGGTGCTAAAAGCTTAGAAATGAATCGACCATTACAACGTTACTATCGTGACATGCGTGCAGGATTACACAATCCAC
CTATGGAAGATGCAGCATATACAAATATTGCTAAGAGTATTACAGATACATTTTAA

Upstream 100 bases:

>100_bases
CCAATTTCCATATAAAAATATTGAATGGTTAATTAAAGAAGGTTATGGAAAATTAACGTTACCAAAAGCATATGGTGGTG
AAGGTGCGACCATAGAAGAC

Downstream 100 bases:

>100_bases
ATTTTAAAAGGTAAATCGATCGTTGATTGGCATAAAGAGATGAAATTTGACGTTCGGATTTACCCTTTTTTTGTGGGGAT
TTATAGGGATGTTAAGATAT

Product: acyl-CoA dehydrogenase-related protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MVILQSFLGELDGATALSIGWHVSVVGQIYEQKLWSQDMLEQFAVEINNGALVNRAVSEAEMGSPTRGGRPSTHAVKADD
GYILNGVKTYTSMSKALTHIIVAAYIEELESVGFFLVDRNLPGVEIADNWDVLGMRATESHDLILNDVKVPLKHLVETEK
SKAPNGWILHIPSCYLGIAQAARNYAVDFAIQHSPNSIEGTIATLPTVQQNLGKMETLLLCARQFLWSTAKGYQQYKDDS
QIRNPTSASKVMVMNQGLEVIDLAMRIVGAKSLEMNRPLQRYYRDMRAGLHNPPMEDAAYTNIAKSITDTF

Sequences:

>Translated_311_residues
MVILQSFLGELDGATALSIGWHVSVVGQIYEQKLWSQDMLEQFAVEINNGALVNRAVSEAEMGSPTRGGRPSTHAVKADD
GYILNGVKTYTSMSKALTHIIVAAYIEELESVGFFLVDRNLPGVEIADNWDVLGMRATESHDLILNDVKVPLKHLVETEK
SKAPNGWILHIPSCYLGIAQAARNYAVDFAIQHSPNSIEGTIATLPTVQQNLGKMETLLLCARQFLWSTAKGYQQYKDDS
QIRNPTSASKVMVMNQGLEVIDLAMRIVGAKSLEMNRPLQRYYRDMRAGLHNPPMEDAAYTNIAKSITDTF
>Mature_311_residues
MVILQSFLGELDGATALSIGWHVSVVGQIYEQKLWSQDMLEQFAVEINNGALVNRAVSEAEMGSPTRGGRPSTHAVKADD
GYILNGVKTYTSMSKALTHIIVAAYIEELESVGFFLVDRNLPGVEIADNWDVLGMRATESHDLILNDVKVPLKHLVETEK
SKAPNGWILHIPSCYLGIAQAARNYAVDFAIQHSPNSIEGTIATLPTVQQNLGKMETLLLCARQFLWSTAKGYQQYKDDS
QIRNPTSASKVMVMNQGLEVIDLAMRIVGAKSLEMNRPLQRYYRDMRAGLHNPPMEDAAYTNIAKSITDTF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=239, Percent_Identity=26.3598326359833, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=301, Percent_Identity=25.2491694352159, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646207, Length=245, Percent_Identity=28.1632653061224, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21355753, Length=301, Percent_Identity=25.2491694352159, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356377, Length=238, Percent_Identity=25.6302521008403, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 34414; Mature: 34414

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILQSFLGELDGATALSIGWHVSVVGQIYEQKLWSQDMLEQFAVEINNGALVNRAVSEA
CEEHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EMGSPTRGGRPSTHAVKADDGYILNGVKTYTSMSKALTHIIVAAYIEELESVGFFLVDRN
HCCCCCCCCCCCCCEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
LPGVEIADNWDVLGMRATESHDLILNDVKVPLKHLVETEKSKAPNGWILHIPSCYLGIAQ
CCCCEECCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHH
AARNYAVDFAIQHSPNSIEGTIATLPTVQQNLGKMETLLLCARQFLWSTAKGYQQYKDDS
HHHHHEEEEEEECCCCCCCEEHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QIRNPTSASKVMVMNQGLEVIDLAMRIVGAKSLEMNRPLQRYYRDMRAGLHNPPMEDAAY
HHCCCCCHHEEEEECCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHCCCCCCCCCHHHH
TNIAKSITDTF
HHHHHHHHCCC
>Mature Secondary Structure
MVILQSFLGELDGATALSIGWHVSVVGQIYEQKLWSQDMLEQFAVEINNGALVNRAVSEA
CEEHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EMGSPTRGGRPSTHAVKADDGYILNGVKTYTSMSKALTHIIVAAYIEELESVGFFLVDRN
HCCCCCCCCCCCCCEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
LPGVEIADNWDVLGMRATESHDLILNDVKVPLKHLVETEKSKAPNGWILHIPSCYLGIAQ
CCCCEECCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHH
AARNYAVDFAIQHSPNSIEGTIATLPTVQQNLGKMETLLLCARQFLWSTAKGYQQYKDDS
HHHHHEEEEEEECCCCCCCEEHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QIRNPTSASKVMVMNQGLEVIDLAMRIVGAKSLEMNRPLQRYYRDMRAGLHNPPMEDAAY
HHCCCCCHHEEEEECCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHCCCCCCCCCHHHH
TNIAKSITDTF
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]