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The map label for this gene is lytA [H]

Identifier: 151221981

GI number: 151221981

Start: 1980874

End: 1982328

Strand: Reverse

Name: lytA [H]

Synonym: NWMN_1769

Alternate gene names: 151221981

Gene position: 1982328-1980874 (Counterclockwise)

Preceding gene: 151221982

Following gene: 151221980

Centisome position: 68.86

GC content: 34.57

Gene sequence:

>1455_bases
ATGTTAATGACAAAAAATCAAGCAGAAAAATGGTTTGACAATTCATTAGGGAAACAATTCAACCCAGATGGTTGGTATGG
ATTTCAGTGTTATGATTACGCCAATATGTTCTTTATGTTAGCGACAGGCGAAAGGCTGCAAGGTTTATATGCTTATAATA
TCCCGTTTGATAATAAAGCAAAGATTGAAAAATATGGTCAAATAATTAAAAACTATGACAGCTTTTTACCGCAAAAGTTG
GATATTGTCGTTTTCCCGTCAAAGTATGGTGGCGGAGCTGGACACGTTGAAATTGTTGAGAGCGCAAATTTAAATACTTT
CACATCATTTGGTCAAAACTGGAACGGTAAAGGTTGGACTAATGGCGTTGCGCAACCTGGTTGGGGTCCTGAAACTGTGA
CAAGACATGTTCATTATTATGACAATCCAATGTATTTTATTAGGTTAAACTTCCCTAACAACTTAAGCGTTGGCAATAAA
GCTAAAGGTATTATTAAGCAAGCGACTACAAAAAAAGAGGCAGTAATTAAACCTAAAAAAATTATGCTTGTAGCCGGTCA
TGGTTATAACGATCCTGGAGCAGTAGGAAACGGAACAAACGAACGCGATTTTATACGTAAATATATAACGCCTAATATCG
CTAAGTATTTAAGACATGCAGGACATGAAGTTGCATTATACGGTGGCTCAAGTCAATCACAAGATATGTATCAAGATACT
GCATACGGTGTTAATGTAGGCAATAAAAAAGATTATGGCTTATATTGGGTTAAATCACAGGGGTATGACATTGTTCTAGA
AATACATTTAGACGCAGCAGGAGAAAGCGCAAGTGGTGGGCATGTTATTATCTCAAGTCAATTCAATGCAGATACTATTG
ATAAAAGTATACAAGATGTTATTAAAAATAACTTAGGACAAATAAGAGGTGTGACACCTCGTAATGATTTACTAAATGTT
AATGTATCAGCAGAAATAAATATAAATTATCGTTTATCTGAATTAGGTTTTATTACTAATAAAAATGATATGGATTGGAT
TAAGAAAAACTATGACTTGTATTCTAAATTAATAGCCGGTGCGATTCATGGTAAGCCTATAGGTGGTTTGGTAGCTGGTA
ATGTTAAAACATCAGCTAAAAACAAAAAAAATCCACCAGTGCCAGCAGGTTATACACTCGATAAGAATAATGTCCCTTAT
AAAAAAGAACAAGGCAATTACACAGTAGCTAATGTTAAAGGTAATAATGTAAGAGACGGTTATTCAACTAATTCAAGAAT
TACAGGGGTATTACCCAACAACACAACAATTACGTATGACGGTGCATATTGTATTAATGGTTATAGATGGATTACTTATA
TTGCTAATAGTGGACAACGTCGTTATATAGCGACAGGAGAGGTAGACAAGGCAGGTAATAGAATAAGTAGTTTTGGTAAG
TTTAGCACGATTTAG

Upstream 100 bases:

>100_bases
AAAGTAAATATAGAAAAGCAACAGGACAAGCACCTATTAAAGAAGTAATGACACCTACGAATATGAACGACACAAATGAT
TTAGGGTAGGTGGTTGATAT

Downstream 100 bases:

>100_bases
TATTTACTTAGAATAAAAATTTTGCTACATTAATTATAGGGAATCTTACAGTTATTAAATAACTATTTGGATGGATGTTA
ATATTCCTATACACTTTTTA

Product: phage amidase

Products: NA

Alternate protein names: N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MLMTKNQAEKWFDNSLGKQFNPDGWYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKAKIEKYGQIIKNYDSFLPQKL
DIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNK
AKGIIKQATTKKEAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNV
NVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVKTSAKNKKNPPVPAGYTLDKNNVPY
KKEQGNYTVANVKGNNVRDGYSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDKAGNRISSFGK
FSTI

Sequences:

>Translated_484_residues
MLMTKNQAEKWFDNSLGKQFNPDGWYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKAKIEKYGQIIKNYDSFLPQKL
DIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNK
AKGIIKQATTKKEAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNV
NVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVKTSAKNKKNPPVPAGYTLDKNNVPY
KKEQGNYTVANVKGNNVRDGYSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDKAGNRISSFGK
FSTI
>Mature_484_residues
MLMTKNQAEKWFDNSLGKQFNPDGWYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKAKIEKYGQIIKNYDSFLPQKL
DIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNK
AKGIIKQATTKKEAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNV
NVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVKTSAKNKKNPPVPAGYTLDKNNVPY
KKEQGNYTVANVKGNNVRDGYSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDKAGNRISSFGK
FSTI

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase C51 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR007921
- InterPro:   IPR003646
- InterPro:   IPR013667 [H]

Pfam domain/function: PF01510 Amidase_2; PF05257 CHAP; PF08460 SH3_5 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 53801; Mature: 53801

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMTKNQAEKWFDNSLGKQFNPDGWYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKA
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCHHCCEEEEECCCCCCH
KIEKYGQIIKNYDSFLPQKLDIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWT
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCC
NGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNKAKGIIKQATTKKEAVIKPKK
CCCCCCCCCHHHHEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHEECCEE
IMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
EEEEECCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDV
HCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHH
IKNNLGQIRGVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAG
HHCCHHHEECCCCCCCEEEEEEEEEEEEEEEEHHCCEEECCCCHHHHHHHHHHHHHHHHH
AIHGKPIGGLVAGNVKTSAKNKKNPPVPAGYTLDKNNVPYKKEQGNYTVANVKGNNVRDG
HHCCCCCCCEEECCEEECCCCCCCCCCCCCEEECCCCCCCEECCCCEEEEEECCCCCCCC
YSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDKAGNRISSFGK
CCCCCEEEEECCCCCEEEECCEEEECCEEEEEEEECCCCEEEEEECCCHHCCCHHHHCCC
FSTI
CCCC
>Mature Secondary Structure
MLMTKNQAEKWFDNSLGKQFNPDGWYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKA
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCHHCCEEEEECCCCCCH
KIEKYGQIIKNYDSFLPQKLDIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWT
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCC
NGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNKAKGIIKQATTKKEAVIKPKK
CCCCCCCCCHHHHEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHEECCEE
IMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
EEEEECCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDV
HCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHH
IKNNLGQIRGVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAG
HHCCHHHEECCCCCCCEEEEEEEEEEEEEEEEHHCCEEECCCCHHHHHHHHHHHHHHHHH
AIHGKPIGGLVAGNVKTSAKNKKNPPVPAGYTLDKNNVPYKKEQGNYTVANVKGNNVRDG
HHCCCCCCCEEECCEEECCCCCCCCCCCCCEEECCCCCCCEECCCCEEEEEECCCCCCCC
YSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDKAGNRISSFGK
CCCCCEEEEECCCCCEEEECCEEEECCEEEEEEEECCCCEEEEEECCCHHCCCHHHHCCC
FSTI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1677905 [H]