BacMap

Definition	Sinorhizobium medicae WSM419 chromosome, complete genome.
Accession	NC_009636
Length	3,781,904

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The map label for this gene is fabG [H]

Identifier: 150398753

GI number: 150398753

Start: 3776678

End: 3777457

Strand: Reverse

Name: fabG [H]

Synonym: Smed_3570

Alternate gene names: 150398753

Gene position: 3777457-3776678 (Counterclockwise)

Preceding gene: 150398754

Following gene: 150398752

Centisome position: 99.88

GC content: 66.67

Gene sequence:

>780_bases
ATGGATCTCGGCATCGAAGGCAAAAAAGCGCTTGTTCTGGGCGGCAGCAAGGGGCTTGGGCGCGGTATCGCCGAAGCGCT
TGCGGCCGAAGGCGTTGCGGTCGCCTTGACCGGCCGGAACGAAGAGACCGCAGGCAGGGCCGCGGCGGAAATCAGTCCGG
ATGCCCTCGGCTTTGCGCTCGATCTGGCCGGGTCCGAGGCCATCGATCCGTTCCTTGACCGGCTCGCCTCCGCCTTCGGT
CCGATCGACATTCTGGTGCTGAACGGAGGCGGTCCCCCGCCCACCCATGCCAGCGACATTGATCCGGATTTCTGGCGGGC
TCAATTCGAGGCGATGGTGCTTTCCGCGATGCGTATCGCCCACCGGCTGCTTCCGCCGATGCGGGCGCGCGGCTTCGGCC
GCATCATCGCCGTCGCCTCCACCAGCATTCGCGAGCCGATCCCCGGACTGACGGCCTCCAACGCGCTGCGCAGCGCACTT
GCCGGCTGGATGAAGACGCTCGCCGGTGAGGTCGCAGCCGAAGGCGTGACCGTCAACATGCTGTTGCCGGGCCGGCTTGC
GACGGACCGGACGCTGAGTTTCGACCGAATGGATGCAGAGGCCGAGGGCGTCAGCGTCGAAACCATCGCCGCGCGCAGCC
AGGTGGAAATTCCGGTCGGGCGTTATGGGACGCCTGTCGAGTTCGGTGCTGCCGCCGCCTTTCTCGCAAGCCGCCAAGCC
GCCTATATCACCGGAATTGCGCTTCCCGTCGATGGCGGCCTCAGCCGGTCGATGCTGTGA

Upstream 100 bases:

>100_bases
CCTGGCAGCTTGCGTGACGGTTGATAGAATGCCGCTCGCCTGAGGCTCCGAACCATCCCCCGCTGGGGTGAGAAAGCTGT
CGAAGCAGGAGGAATGAACC

Downstream 100 bases:

>100_bases
CCGTGTCCGCGATCTGCATCAGAATGAACGGGACGAGGACTTGGTGGTGGCGGATCATCGCCTCCCTTTTCGTGATCATA
GCGCTGAACCGAGAGGGAGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDLGIEGKKALVLGGSKGLGRGIAEALAAEGVAVALTGRNEETAGRAAAEISPDALGFALDLAGSEAIDPFLDRLASAFG
PIDILVLNGGGPPPTHASDIDPDFWRAQFEAMVLSAMRIAHRLLPPMRARGFGRIIAVASTSIREPIPGLTASNALRSAL
AGWMKTLAGEVAAEGVTVNMLLPGRLATDRTLSFDRMDAEAEGVSVETIAARSQVEIPVGRYGTPVEFGAAAAFLASRQA
AYITGIALPVDGGLSRSML

Sequences:

>Translated_259_residues
MDLGIEGKKALVLGGSKGLGRGIAEALAAEGVAVALTGRNEETAGRAAAEISPDALGFALDLAGSEAIDPFLDRLASAFG
PIDILVLNGGGPPPTHASDIDPDFWRAQFEAMVLSAMRIAHRLLPPMRARGFGRIIAVASTSIREPIPGLTASNALRSAL
AGWMKTLAGEVAAEGVTVNMLLPGRLATDRTLSFDRMDAEAEGVSVETIAARSQVEIPVGRYGTPVEFGAAAAFLASRQA
AYITGIALPVDGGLSRSML
>Mature_259_residues
MDLGIEGKKALVLGGSKGLGRGIAEALAAEGVAVALTGRNEETAGRAAAEISPDALGFALDLAGSEAIDPFLDRLASAFG
PIDILVLNGGGPPPTHASDIDPDFWRAQFEAMVLSAMRIAHRLLPPMRARGFGRIIAVASTSIREPIPGLTASNALRSAL
AGWMKTLAGEVAAEGVTVNMLLPGRLATDRTLSFDRMDAEAEGVSVETIAARSQVEIPVGRYGTPVEFGAAAAFLASRQA
AYITGIALPVDGGLSRSML

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=31.1023622047244, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI40254992, Length=257, Percent_Identity=30.3501945525292, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=25.8687258687259, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=25.9842519685039, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=266, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=30.0518134715026, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=28.042328042328, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI59889578, Length=219, Percent_Identity=28.310502283105, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI20149619, Length=217, Percent_Identity=27.6497695852535, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=25.4826254826255, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=27.6243093922652, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=34.1269841269841, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082100, Length=264, Percent_Identity=31.4393939393939, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=26.8482490272374, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=29.1187739463602, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=31.6602316602317, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=28.8, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=28.0155642023346, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=23.1372549019608, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=29.0697674418605, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789057, Length=252, Percent_Identity=26.5873015873016, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787545, Length=274, Percent_Identity=26.2773722627737, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=30.7392996108949, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=29.8039215686275, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=31.8897637795276, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=30.7392996108949, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.1954887218045, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=28.3524904214559, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=28.2945736434109, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=29.6703296703297, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=27.9245283018868, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=27.9245283018868, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=279, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=28.1368821292776, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=25.7575757575758, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=26.615969581749, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=28.0442804428044, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=25.1908396946565, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=283, Percent_Identity=27.5618374558304, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=262, Percent_Identity=26.3358778625954, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=29.368029739777, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=25.6809338521401, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=29.6442687747036, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=30.9160305343511, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=29.7619047619048, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=31.2252964426877, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=30.7392996108949, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358495, Length=231, Percent_Identity=27.7056277056277, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=30.46875, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26688; Mature: 26688

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIEGKKALVLGGSKGLGRGIAEALAAEGVAVALTGRNEETAGRAAAEISPDALGFAL
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCHHCCCHHHCCCCCHHEEEE
DLAGSEAIDPFLDRLASAFGPIDILVLNGGGPPPTHASDIDPDFWRAQFEAMVLSAMRIA
ECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HRLLPPMRARGFGRIIAVASTSIREPIPGLTASNALRSALAGWMKTLAGEVAAEGVTVNM
HHHCCCHHHCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
LLPGRLATDRTLSFDRMDAEAEGVSVETIAARSQVEIPVGRYGTPVEFGAAAAFLASRQA
EECCCCCCCCCCCHHHCCCCCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHCCC
AYITGIALPVDGGLSRSML
EEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MDLGIEGKKALVLGGSKGLGRGIAEALAAEGVAVALTGRNEETAGRAAAEISPDALGFAL
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCHHCCCHHHCCCCCHHEEEE
DLAGSEAIDPFLDRLASAFGPIDILVLNGGGPPPTHASDIDPDFWRAQFEAMVLSAMRIA
ECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HRLLPPMRARGFGRIIAVASTSIREPIPGLTASNALRSALAGWMKTLAGEVAAEGVTVNM
HHHCCCHHHCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
LLPGRLATDRTLSFDRMDAEAEGVSVETIAARSQVEIPVGRYGTPVEFGAAAAFLASRQA
EECCCCCCCCCCCHHHCCCCCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHCCC
AYITGIALPVDGGLSRSML
EEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]