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The map label for this gene is iolC [H]

Identifier: 150398745

GI number: 150398745

Start: 3767908

End: 3769875

Strand: Reverse

Name: iolC [H]

Synonym: Smed_3562

Alternate gene names: 150398745

Gene position: 3769875-3767908 (Counterclockwise)

Preceding gene: 150398746

Following gene: 150398744

Centisome position: 99.68

GC content: 62.35

Gene sequence:

>1968_bases
GTGAGCCAGATTTCATCGGCTGAAGTTCCATCGGCTGACATTCCTGCAACAGAGGGAACCAGGCCTCTCGACATCATCAC
GATCGGCAGAGCCTCGGTCGATCTTTACGGGCAGCAGATCGGCACGCGGCTGGAAGACGTGGCGAGCTTTGCCAAGTCGG
TCGGCGGCTGCCCCTGCAACATCTCGGTCGGTACCGCGCGACTTGGCCTGAGATCCGCCTTGCTGACCCGCGTCGGCAAC
GAGCAGATGGGCCGCTTCATTCGCGAGCAGCTTCAGCGTGAAGGGGTCGAGACGCGCGGCATCGTCACCGATCCGGAGCG
GTTGACCGCGCTTGCGATTCTTTCCGTCGAAAACGAAAAATCCTTCCCGCTGCTCTTTTACCGCGACAATTGCGCCGATA
ACGCGCTCAGCGAGGATGATGTGGCGGAAGACTTCATTCGCTCCGCGCATGCGATCCTCGTTACCGGCACGCATTTCTCG
AAGCCCAATACGGACGCAGCCCAGCGCAAGGCGATCAGGATTGCCAAGGAAAACGGTTCCAGGATCGTCTTCGACATCGA
CTACCGCCCTAATCTCTGGGGCCTTGCGGGCCACGATGCGGGCGAGAGCCGTTATATAGCCTCCGACCGCGTCTCCGCAC
ATCTGCGAACCGTCCTTGGCGATTGCGACCTGATCGTCGGCACCGAGGAAGAAGTGCTGATCGCATCAGGCGAAAACGAT
CTGCTCGCGGCGCTCAAGTCCATCCGCTCGCTTTCCAAGGCCACGATCGTGCTCAAACGCGGACCGATGGGCTGCATCGT
CTATGACGGACCGATCTCGGACGACCTCGAAGACGGTATCGTCGGCAAGGGCTTCCCAATCGAGGTTTACAACGTCCTTG
GCGCCGGCGATGCTTTCATGTCCGGTTTCCTGCGCGGCTGGCTGAGGGGCGAGCCGCATGCGACCTGCGCGACCTGGGCG
AATGCCTGCGGCGCCTTCGCGGTTTCCCGCCTGCTCTGCGCGCCTGAAATCCCGACCTGGACCGAGCTGCAGTACTTCCT
CGAGCACGGCAGCAAGGTGAAGGCGCTTCGCAAGGACGAGGCGATCAACCACGTGCATTGGGCAACGACGCGCAGGCGCG
AGATACCGCTGCTGATGGCGCTTGCCGTCGATCACCGCAGCCAGCTCGAAGACATTGCCGAGGGAAATCCGGAACTGCTC
TCGCGCATACCGGCCTTCAAGGTCCTCGCCGTCAAGGCGGCGGCGGAGGTGGCCGCCGGCCGCTCCGGCTTCGGGATGCT
CATCGACGACAAATACGGACGCGATGCGCTTTATGCTGCCGGCGCCTATCGCGATTTCTGGATCGGAAAGCCCGTCGAGC
TGCCGGGCTCGCGGCCGTTGCAGTTCGAATTCAGCCAGGATCTCGGCAGCCGCCTTATCGAGTGGCCGGTCGACCATTGC
ATCAAAGTGCTTTCCTTCTACCACCCTGACGATCCGGCCGAACTCAAGACCGCCCAGATTGCCAAGCTTCGTTCGGCCTT
CGAGGCGGCGCGCAAGGTCGGACGCGAGATCCTGATCGAGATCATCGCCGGCAAGCATGGACCACTCGACGACCGGACTG
TACCGAGAGCGCTCGAGGAACTCTATGATGCAGGCTTGAAGCCGGACTGGTGGAAGCTCGAGCCCCAGGCAAGCCGCGCA
GCCTGGAGAGCCATCGATGCCGTGATCGAGCGGCGCGACCCGCTTTGCCGGGGCGTGGTGCTCCTCGGCCTGGAAGCACC
CTATGAAGTGCTGAAGAATGGGTTCGCGGCGGCCAGAACATCGAAGACGGTCAGGGGATTTGCCGTCGGAAGGACGATCT
TCGCCGATGCCGCCAGAGCCTGGCTCTCCGGCGGGATGACCGACGAACAGGCGATCACCGACATGGCGGCAAAGTTCAAG
GCACTCGTGGATCTTTGGCTGCAACTGGGCGAGACCAGGGATCTATAG

Upstream 100 bases:

>100_bases
TCCATATTGACGAGGCAACGGAATTTATGTTTCATATGCCCGTGACCCATGGCATGAGTATAATTGTCGGCGCCGACCCG
GCGTCCACGGGGAGGATGCA

Downstream 100 bases:

>100_bases
TGGTCAAATAGGAAGCGGCACGGATTCGGCCGCGAGGAGGAGACAATGACCCAGAAAACCGTGCGCCAGGGTACAGTGCG
CTTGACCATGTCGCAGGCCG

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 655; Mature: 654

Protein sequence:

>655_residues
MSQISSAEVPSADIPATEGTRPLDIITIGRASVDLYGQQIGTRLEDVASFAKSVGGCPCNISVGTARLGLRSALLTRVGN
EQMGRFIREQLQREGVETRGIVTDPERLTALAILSVENEKSFPLLFYRDNCADNALSEDDVAEDFIRSAHAILVTGTHFS
KPNTDAAQRKAIRIAKENGSRIVFDIDYRPNLWGLAGHDAGESRYIASDRVSAHLRTVLGDCDLIVGTEEEVLIASGEND
LLAALKSIRSLSKATIVLKRGPMGCIVYDGPISDDLEDGIVGKGFPIEVYNVLGAGDAFMSGFLRGWLRGEPHATCATWA
NACGAFAVSRLLCAPEIPTWTELQYFLEHGSKVKALRKDEAINHVHWATTRRREIPLLMALAVDHRSQLEDIAEGNPELL
SRIPAFKVLAVKAAAEVAAGRSGFGMLIDDKYGRDALYAAGAYRDFWIGKPVELPGSRPLQFEFSQDLGSRLIEWPVDHC
IKVLSFYHPDDPAELKTAQIAKLRSAFEAARKVGREILIEIIAGKHGPLDDRTVPRALEELYDAGLKPDWWKLEPQASRA
AWRAIDAVIERRDPLCRGVVLLGLEAPYEVLKNGFAAARTSKTVRGFAVGRTIFADAARAWLSGGMTDEQAITDMAAKFK
ALVDLWLQLGETRDL

Sequences:

>Translated_655_residues
MSQISSAEVPSADIPATEGTRPLDIITIGRASVDLYGQQIGTRLEDVASFAKSVGGCPCNISVGTARLGLRSALLTRVGN
EQMGRFIREQLQREGVETRGIVTDPERLTALAILSVENEKSFPLLFYRDNCADNALSEDDVAEDFIRSAHAILVTGTHFS
KPNTDAAQRKAIRIAKENGSRIVFDIDYRPNLWGLAGHDAGESRYIASDRVSAHLRTVLGDCDLIVGTEEEVLIASGEND
LLAALKSIRSLSKATIVLKRGPMGCIVYDGPISDDLEDGIVGKGFPIEVYNVLGAGDAFMSGFLRGWLRGEPHATCATWA
NACGAFAVSRLLCAPEIPTWTELQYFLEHGSKVKALRKDEAINHVHWATTRRREIPLLMALAVDHRSQLEDIAEGNPELL
SRIPAFKVLAVKAAAEVAAGRSGFGMLIDDKYGRDALYAAGAYRDFWIGKPVELPGSRPLQFEFSQDLGSRLIEWPVDHC
IKVLSFYHPDDPAELKTAQIAKLRSAFEAARKVGREILIEIIAGKHGPLDDRTVPRALEELYDAGLKPDWWKLEPQASRA
AWRAIDAVIERRDPLCRGVVLLGLEAPYEVLKNGFAAARTSKTVRGFAVGRTIFADAARAWLSGGMTDEQAITDMAAKFK
ALVDLWLQLGETRDL
>Mature_654_residues
SQISSAEVPSADIPATEGTRPLDIITIGRASVDLYGQQIGTRLEDVASFAKSVGGCPCNISVGTARLGLRSALLTRVGNE
QMGRFIREQLQREGVETRGIVTDPERLTALAILSVENEKSFPLLFYRDNCADNALSEDDVAEDFIRSAHAILVTGTHFSK
PNTDAAQRKAIRIAKENGSRIVFDIDYRPNLWGLAGHDAGESRYIASDRVSAHLRTVLGDCDLIVGTEEEVLIASGENDL
LAALKSIRSLSKATIVLKRGPMGCIVYDGPISDDLEDGIVGKGFPIEVYNVLGAGDAFMSGFLRGWLRGEPHATCATWAN
ACGAFAVSRLLCAPEIPTWTELQYFLEHGSKVKALRKDEAINHVHWATTRRREIPLLMALAVDHRSQLEDIAEGNPELLS
RIPAFKVLAVKAAAEVAAGRSGFGMLIDDKYGRDALYAAGAYRDFWIGKPVELPGSRPLQFEFSQDLGSRLIEWPVDHCI
KVLSFYHPDDPAELKTAQIAKLRSAFEAARKVGREILIEIIAGKHGPLDDRTVPRALEELYDAGLKPDWWKLEPQASRAA
WRAIDAVIERRDPLCRGVVLLGLEAPYEVLKNGFAAARTSKTVRGFAVGRTIFADAARAWLSGGMTDEQAITDMAAKFKA
LVDLWLQLGETRDL

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=314, Percent_Identity=26.4331210191083, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 71685; Mature: 71553

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQISSAEVPSADIPATEGTRPLDIITIGRASVDLYGQQIGTRLEDVASFAKSVGGCPCN
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ISVGTARLGLRSALLTRVGNEQMGRFIREQLQREGVETRGIVTDPERLTALAILSVENEK
EECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEEECCCC
SFPLLFYRDNCADNALSEDDVAEDFIRSAHAILVTGTHFSKPNTDAAQRKAIRIAKENGS
CCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHEEEECCCC
RIVFDIDYRPNLWGLAGHDAGESRYIASDRVSAHLRTVLGDCDLIVGTEEEVLIASGEND
EEEEEECCCCCCCEECCCCCCCCCEEHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCHH
LLAALKSIRSLSKATIVLKRGPMGCIVYDGPISDDLEDGIVGKGFPIEVYNVLGAGDAFM
HHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCHHCCCCCCCCCEEEHHHHCCCHHHH
SGFLRGWLRGEPHATCATWANACGAFAVSRLLCAPEIPTWTELQYFLEHGSKVKALRKDE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
AINHVHWATTRRREIPLLMALAVDHRSQLEDIAEGNPELLSRIPAFKVLAVKAAAEVAAG
HHCHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCC
RSGFGMLIDDKYGRDALYAAGAYRDFWIGKPVELPGSRPLQFEFSQDLGSRLIEWPVDHC
CCCCEEEEECCCCCCHHEECCCCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCHHHH
IKVLSFYHPDDPAELKTAQIAKLRSAFEAARKVGREILIEIIAGKHGPLDDRTVPRALEE
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LYDAGLKPDWWKLEPQASRAAWRAIDAVIERRDPLCRGVVLLGLEAPYEVLKNGFAAART
HHHCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHCEEEEECCCCHHHHHCCHHHHHH
SKTVRGFAVGRTIFADAARAWLSGGMTDEQAITDMAAKFKALVDLWLQLGETRDL
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQISSAEVPSADIPATEGTRPLDIITIGRASVDLYGQQIGTRLEDVASFAKSVGGCPCN
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ISVGTARLGLRSALLTRVGNEQMGRFIREQLQREGVETRGIVTDPERLTALAILSVENEK
EECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEEECCCC
SFPLLFYRDNCADNALSEDDVAEDFIRSAHAILVTGTHFSKPNTDAAQRKAIRIAKENGS
CCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHEEEECCCC
RIVFDIDYRPNLWGLAGHDAGESRYIASDRVSAHLRTVLGDCDLIVGTEEEVLIASGEND
EEEEEECCCCCCCEECCCCCCCCCEEHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCHH
LLAALKSIRSLSKATIVLKRGPMGCIVYDGPISDDLEDGIVGKGFPIEVYNVLGAGDAFM
HHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCHHCCCCCCCCCEEEHHHHCCCHHHH
SGFLRGWLRGEPHATCATWANACGAFAVSRLLCAPEIPTWTELQYFLEHGSKVKALRKDE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
AINHVHWATTRRREIPLLMALAVDHRSQLEDIAEGNPELLSRIPAFKVLAVKAAAEVAAG
HHCHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCC
RSGFGMLIDDKYGRDALYAAGAYRDFWIGKPVELPGSRPLQFEFSQDLGSRLIEWPVDHC
CCCCEEEEECCCCCCHHEECCCCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCHHHH
IKVLSFYHPDDPAELKTAQIAKLRSAFEAARKVGREILIEIIAGKHGPLDDRTVPRALEE
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LYDAGLKPDWWKLEPQASRAAWRAIDAVIERRDPLCRGVVLLGLEAPYEVLKNGFAAART
HHHCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHCEEEEECCCCHHHHHCCHHHHHH
SKTVRGFAVGRTIFADAARAWLSGGMTDEQAITDMAAKFKALVDLWLQLGETRDL
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA