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The map label for this gene is comM [H]

Identifier: 150398731

GI number: 150398731

Start: 3752813

End: 3754411

Strand: Direct

Name: comM [H]

Synonym: Smed_3547

Alternate gene names: 150398731

Gene position: 3752813-3754411 (Clockwise)

Preceding gene: 150398730

Following gene: 150398732

Centisome position: 99.23

GC content: 67.79

Gene sequence:

>1599_bases
ATGCCGTATCGGGTTATGCGGAAGGGGCAATGGTCTTTCGCGCTCAGCTCGAATTCAGGGGGCGTCATGGTCGCGCGCGT
CAGCACGGTTGCGTTTCAGGGTATCGAGGGCCTTCCGGTCGACGTCCAGGTGATGGTAGCGCCCGGCAGGGTCGGCATGC
AGATCGTCGGGCTGCCGGATAAAGCGGTCGCTGAAAGCCGCGAGCGCGTTCAGGCGGCGCTGCATGCATCTGGACTGGCG
CTTCCCGCAAAGCGCGTCACGGTCAATCTGGCGCCGGCGGATTTGCCGAAGGAAGGAAGTCATTTCGATCTCGCCATCGC
GCTTGGCCTGATGGCGGCGCTCGGTGCTGTCCCGGCGGACGCGCTGTCCAATTATATCGTCATTGGCGAGCTCAATCTGG
ACGGCACGATCGCCGCCGTTGCCGGTGCCTTGCCGGCGGCGATCGGCGCGAATGCGCTCGGCAAGGGGCTGATCTGCCCC
GCCGATAGCGGACCGGAGGCGGCCTGGGCCGGCTCGGAGATCGACATTCTCGCCCCGCGCAGCCTGATCGCGATTGCCAA
TCACTTCCGCGGCACGCAGGTGCTCTCCCGTCCGGAGCCGGCGGTGCGGATGGCGGCCGCAGGCCTTCCCGATCTCTCCG
ATATCAAGGGTCAGGAAAGCGCCAAGCGGGCGCTGGAGGTGGCCGCCGCCGGCAATCATAATCTCCTGATGGTCGGCCCG
CCGGGTTCCGGCAAGTCGATGCTCGCGGCGCGGCTCCCGTCCATTCTGCCGCCGCTTTCGCCCGCCGAACTGCTCGAAGT
CTCCATGATCCATTCGATTGCCGGACAGCTTCCAGGCGGCAAGCTCTCCGACAGCCGGCCGTTTCGCGCGCCGCACCACT
CCGCCACCATGGCGGCGCTCATCGGTGGCGGCGCTCGCGCCAAACCGGGCGAGGCATCGCTCGCCCACCACGGCGTGCTC
TTCCTCGACGAGTTTCCGGAATTTGCGCCGCAGGTTCTCGATGCCTTGCGCCAGCCGCTCGAAACCGCCACATGCATAAT
CGCGCGCGCCAATCACCGCGTCACCTATCCGGCGGCGATCCAGCTCATCGCAGCCATGAACCCCTGCCGCTGCGGCATGG
CCGGCGAACCGGGGCGCAGCTGCGCCCGCGGTCCGCGCTGCATGGCCGACTACCAGGCGCGGATCTCCGGCCCGCTAATG
GATCGCATCGACATCCGTGTCGACGTCCCGGCGGTCAGCGCCGCCGACCTCATTCGCCCCGGCACGTCAGAGCCGAGCGC
TGCCGTCGCCCGCCGCGTCGCCCGCGCCCGCGAGCTGCAGAGAGACCGCTTCGCCGTCCTCGGGCATGCCGAGCTCACGA
GCAATGCCCGCTCGTCGACGACGGTGATCGAAAAAATCGCCGAGCCCGACGCGGCCGGCCTGCAGCTTCTGAGAGATGCT
GCGGAGAAGATGAAGTTCTCGGCGCGCGGCTATCACCGGGTGTTGAAGGTGGCTCGCACGCTTGCCGACCTGGACGAGGC
GCCGAGGGTTGGCCGCATTCATCTGGCCGAGGCGATTTCCTATCGAATGGCGGGGGAGCGGCTGCCGGTGGCGGCATAG

Upstream 100 bases:

>100_bases
TCATCCTTCATTGTTCTGTAATTGTTCTTGTTTTTAAGCGCATTCCGTGCAAGGTTTGCCGATGCAACCGAATTCGGTTG
TGACGGCGGCGTGAGCCGCC

Downstream 100 bases:

>100_bases
GGATTGCGTGAGTTCAATGAAAAAAGCCGTCGTCGAGGATCATGAGGCGAGTTACCCAGATCCGATCGCGGTCGAGGCCG
GCCAGGTCATCAGGCCGACC

Product: Mg chelatase subunit ChlI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MPYRVMRKGQWSFALSSNSGGVMVARVSTVAFQGIEGLPVDVQVMVAPGRVGMQIVGLPDKAVAESRERVQAALHASGLA
LPAKRVTVNLAPADLPKEGSHFDLAIALGLMAALGAVPADALSNYIVIGELNLDGTIAAVAGALPAAIGANALGKGLICP
ADSGPEAAWAGSEIDILAPRSLIAIANHFRGTQVLSRPEPAVRMAAAGLPDLSDIKGQESAKRALEVAAAGNHNLLMVGP
PGSGKSMLAARLPSILPPLSPAELLEVSMIHSIAGQLPGGKLSDSRPFRAPHHSATMAALIGGGARAKPGEASLAHHGVL
FLDEFPEFAPQVLDALRQPLETATCIIARANHRVTYPAAIQLIAAMNPCRCGMAGEPGRSCARGPRCMADYQARISGPLM
DRIDIRVDVPAVSAADLIRPGTSEPSAAVARRVARARELQRDRFAVLGHAELTSNARSSTTVIEKIAEPDAAGLQLLRDA
AEKMKFSARGYHRVLKVARTLADLDEAPRVGRIHLAEAISYRMAGERLPVAA

Sequences:

>Translated_532_residues
MPYRVMRKGQWSFALSSNSGGVMVARVSTVAFQGIEGLPVDVQVMVAPGRVGMQIVGLPDKAVAESRERVQAALHASGLA
LPAKRVTVNLAPADLPKEGSHFDLAIALGLMAALGAVPADALSNYIVIGELNLDGTIAAVAGALPAAIGANALGKGLICP
ADSGPEAAWAGSEIDILAPRSLIAIANHFRGTQVLSRPEPAVRMAAAGLPDLSDIKGQESAKRALEVAAAGNHNLLMVGP
PGSGKSMLAARLPSILPPLSPAELLEVSMIHSIAGQLPGGKLSDSRPFRAPHHSATMAALIGGGARAKPGEASLAHHGVL
FLDEFPEFAPQVLDALRQPLETATCIIARANHRVTYPAAIQLIAAMNPCRCGMAGEPGRSCARGPRCMADYQARISGPLM
DRIDIRVDVPAVSAADLIRPGTSEPSAAVARRVARARELQRDRFAVLGHAELTSNARSSTTVIEKIAEPDAAGLQLLRDA
AEKMKFSARGYHRVLKVARTLADLDEAPRVGRIHLAEAISYRMAGERLPVAA
>Mature_531_residues
PYRVMRKGQWSFALSSNSGGVMVARVSTVAFQGIEGLPVDVQVMVAPGRVGMQIVGLPDKAVAESRERVQAALHASGLAL
PAKRVTVNLAPADLPKEGSHFDLAIALGLMAALGAVPADALSNYIVIGELNLDGTIAAVAGALPAAIGANALGKGLICPA
DSGPEAAWAGSEIDILAPRSLIAIANHFRGTQVLSRPEPAVRMAAAGLPDLSDIKGQESAKRALEVAAAGNHNLLMVGPP
GSGKSMLAARLPSILPPLSPAELLEVSMIHSIAGQLPGGKLSDSRPFRAPHHSATMAALIGGGARAKPGEASLAHHGVLF
LDEFPEFAPQVLDALRQPLETATCIIARANHRVTYPAAIQLIAAMNPCRCGMAGEPGRSCARGPRCMADYQARISGPLMD
RIDIRVDVPAVSAADLIRPGTSEPSAAVARRVARARELQRDRFAVLGHAELTSNARSSTTVIEKIAEPDAAGLQLLRDAA
EKMKFSARGYHRVLKVARTLADLDEAPRVGRIHLAEAISYRMAGERLPVAA

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=499, Percent_Identity=41.8837675350701, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55510; Mature: 55379

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYRVMRKGQWSFALSSNSGGVMVARVSTVAFQGIEGLPVDVQVMVAPGRVGMQIVGLPD
CCCCCCCCCCEEEEEECCCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCC
KAVAESRERVQAALHASGLALPAKRVTVNLAPADLPKEGSHFDLAIALGLMAALGAVPAD
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
ALSNYIVIGELNLDGTIAAVAGALPAAIGANALGKGLICPADSGPEAAWAGSEIDILAPR
HHCCEEEEEEECCCCHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCEEEECCH
SLIAIANHFRGTQVLSRPEPAVRMAAAGLPDLSDIKGQESAKRALEVAAAGNHNLLMVGP
HHHHHHHHCCCCHHHCCCCHHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCEEEECC
PGSGKSMLAARLPSILPPLSPAELLEVSMIHSIAGQLPGGKLSDSRPFRAPHHSATMAAL
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
IGGGARAKPGEASLAHHGVLFLDEFPEFAPQVLDALRQPLETATCIIARANHRVTYPAAI
HCCCCCCCCCCCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEHHHHH
QLIAAMNPCRCGMAGEPGRSCARGPRCMADYQARISGPLMDRIDIRVDVPAVSAADLIRP
HHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCC
GTSEPSAAVARRVARARELQRDRFAVLGHAELTSNARSSTTVIEKIAEPDAAGLQLLRDA
CCCCHHHHHHHHHHHHHHHHHHHEEEEECHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHH
AEKMKFSARGYHRVLKVARTLADLDEAPRVGRIHLAEAISYRMAGERLPVAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PYRVMRKGQWSFALSSNSGGVMVARVSTVAFQGIEGLPVDVQVMVAPGRVGMQIVGLPD
CCCCCCCCCEEEEEECCCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCC
KAVAESRERVQAALHASGLALPAKRVTVNLAPADLPKEGSHFDLAIALGLMAALGAVPAD
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
ALSNYIVIGELNLDGTIAAVAGALPAAIGANALGKGLICPADSGPEAAWAGSEIDILAPR
HHCCEEEEEEECCCCHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCEEEECCH
SLIAIANHFRGTQVLSRPEPAVRMAAAGLPDLSDIKGQESAKRALEVAAAGNHNLLMVGP
HHHHHHHHCCCCHHHCCCCHHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCEEEECC
PGSGKSMLAARLPSILPPLSPAELLEVSMIHSIAGQLPGGKLSDSRPFRAPHHSATMAAL
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
IGGGARAKPGEASLAHHGVLFLDEFPEFAPQVLDALRQPLETATCIIARANHRVTYPAAI
HCCCCCCCCCCCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEHHHHH
QLIAAMNPCRCGMAGEPGRSCARGPRCMADYQARISGPLMDRIDIRVDVPAVSAADLIRP
HHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCC
GTSEPSAAVARRVARARELQRDRFAVLGHAELTSNARSSTTVIEKIAEPDAAGLQLLRDA
CCCCHHHHHHHHHHHHHHHHHHHEEEEECHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHH
AEKMKFSARGYHRVLKVARTLADLDEAPRVGRIHLAEAISYRMAGERLPVAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]