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The map label for this gene is pyc [H]

Identifier: 150398333

GI number: 150398333

Start: 3288619

End: 3292173

Strand: Reverse

Name: pyc [H]

Synonym: Smed_3139

Alternate gene names: 150398333

Gene position: 3292173-3288619 (Counterclockwise)

Preceding gene: 150398334

Following gene: 150398329

Centisome position: 87.05

GC content: 63.23

Gene sequence:

>3555_bases
ATGTCGCGTCTGAAATTGCACTTCATTCCTCGACTCGCTAATAGTCTTTTCGCGGGTGCAGCATTCCCGCGTGTCCAAGA
CCATGAGGAGTCCGACTTGTCCATATCGAAGATCCTTGTCGCCAACCGTTCCGAAATTGCCATCCGCGTCTTCCGCGCGG
CCAATGAGCTGGGGCTTAAAACGGTCGCGATATGGGCTGAGGAGGACAAGCTGGCGCTGCACCGCTTCAAGGCGGACGAG
AGTTATCAGGTCGGACGAGGGCCGCACCTTCCCCGTGACCTCGGGCCGATCGAAAGCTATCTTTCGATCGACGAAGTGAT
CCGCGTCGCCAAGCTGTCCGGCGCGGACGCCATACATCCGGGCTACGGCCTGCTTTCCGAAAGCCCCGAGTTCGCCGAGG
CTTGCGCCGTAAACGGCATCACCTTCATCGGCCCGAAGCCGGAGACGATGCGTCAGCTCGGCAACAAGGTTGCGGCCCGC
AATCTCGCGATCTCCGTTGGCGTGCCGGTCGTGCCGGCGACCGAGCCGTTGCCGGACGATACGGACGAGATCAAGCGGCT
GGCCGAGGAGATCGGCTATCCGGTGATGCTGAAAGCTTCCTGGGGCGGCGGCGGCCGCGGCATGCGGGCGATTCGAGACC
CCAAGGACCTGATCCGCGAGGTGACCGAGGCCAAGCGTGAGGCGAAGGCTGCCTTCGGCAAGGACGAGGTCTATCTCGAG
AAGCTCGTCGAGCGTGCCCGCCACGTCGAAAGCCAGATCCTCGGCGACACGCATGGCAATGTCGTCCACCTGTTCGAGCG
CGACTGCTCGATTCAGCGGCGCAACCAGAAGGTCGTGGAGCGCGCGCCGGCACCCTATCTCACCGAGGCGCAGCGCCAGG
AACTCGCCGACTACTCGCTGAAGATCGCCAGGGCGACCAGCTATATCGGCGCCGGCACGGTCGAGTATCTGATGGATGCC
GACACCGGCAGATTCTACTTCATCGAGGTCAATCCGCGCATCCAGGTCGAGCATACGGTGACCGAGGTCGTCACCGGCAT
CGACATCGTGAAGGCGCAGATCCACATTCTCGACGGCTTTGCCATCGGGTCACCGGAATCGGGCGTGCCGCGTCAGGAGG
ATATCCGTCTTAACGGGCATGCACTGCAATGCCGCATCACGACGGAAGATCCGGAGCAGAATTTCATCCCGGATTACGGT
CGCATCACCGCCTATCGCGGCGCCACCGGCTTCGGCATCCGCCTCGATGGCGGCACCGCCTATTCCGGTGCCGTGATCAC
CCGCTTTTACGACCCGCTTCTCGAGAAGGTGACCGCCTGGGCGCCGAACCCGGACGAGGCGATAAAGCGGATGGTCCGTG
CGTTACGGGAGTTCCGCATCCGTGGCGTGGCCACCAATCTCACCTTCCTCGAGGCGATCATCAGCCACCCGAAATTCCAC
GACAACAGCTATACCACGCGATTCATCGACACGACGCCGGAGCTGTTCCAGCAGGTGAAGCGTCAGGACCGCGCCACCAA
GCTGCTCACCTATCTTGCCGACGTGACCGTCAACGGTCATCCGGAAGCCAAGGGCCGGCCGATGCCCTCAGAGGACATCG
CCTCCCCGCTCGTGCCGTTCATCGGCGACGAGGTGAAGCCGGGAACCAAGCAGCGCCTCGATCAGCTCGGTCCGAAGAAA
TTCGCCGAATGGGTAAAGGCACGCAAGGAAGTGCTGATCACCGACACGACGATGCGCGACGGCCACCAGTCGCTGCTCGC
CACCCGCATGCGCACCTATGACATCGCCCGCATCGCCGACACCTATGCGCGGGCGCTGCCGGGTCTCTTCTCGCTCGAAT
GCTGGGGCGGGGCGACCTTCGACGTCTCGATGCGCTTTCTGACCGAGGATCCGTGGGAGCGGCTGGCGATGGTGCGGGAG
GGCGCGCCGAACCTGCTGCTGCAGATGCTTCTGCGCGGTGCGAACGGTGTCGGCTACAAGAACTATCCCGACAACGTCGT
CAAATATTTCGTCCGCCAGGCCGCCAAGGGCGGCATCGATGTCTTCCGCGTCTTCGACTGCCTGAACTGGGTCGAGAACA
TGCGCGTCTCGATGGATGCGGTGGCGGAAGAGAACAGGATCTGCGAGGCGGCGATCTGCTATACCGGCGATATTCTGAAT
TCAGCCCGGCCGAAATACGACCTGAAATATTATACGGCGCTTGCGGCCGAGCTTGAAAAGGCCGGCGCCCACATGATCGC
CGTCAAGGACATGGCCGGGCTCCTGAAGCCCGCCGCGGCGCGCGTGCTCTTCAAGGCGCTGAAAGAGGCGACCGACCTGC
CGATCCACTTCCACACGCACGACACGTCGGGCATTGCCGCGGCGACGGTGCTCGCAGCCGTCGAATCCGGCGTCGATGTC
GTCGATGCGGCGATGGATGCGCTCTCGGGCAATACCTCGCAGCCCTGCCTCGGGTCGATCGTCGAGGCGCTGTCCGGTTC
GGAGCGCGACCCGGGCCTCGATCCGGAATGGATCCGCCGCATCTCCTTCTACTGGGAGGCCGTTCGCCACCAGTATGCGG
CCTTCGAGAGCGACCTCAAGGGGCCGGCCTCGGAAGTCTATCTGCATGAAATGCCCGGGGGCCAGTTTACCAATCTGAAG
GAACAGGCTCGCTCGCTCGGTCTCGAAACCCGCTGGCACGAGGTTGCACAGGCCTATGCCGACGCGAACCGGATGTTCGG
CGACATCGTCAAGGTGACGCCCTCCTCCAAGGTGGTCGGCGATATGGCGCTGATGATGGTGAGCCAGGACCTGACAGTTG
CCGATGTCGAGAATCCGGGCAAGGACATAGCCTTCCCCGAATCGGTCGTATCCATGCTCAAGGGCGATCTCGGTCAACCG
CCGGGCGGCTGGCCGGAGGCGCTGCAGAAGAAGGCGCTGAAAGGCGAGGTGGCCTATGACGCGCGTCCGGGCTCGCTGCT
CGAAGACGCCGATCTCGACGCCGAACGCAAGGACATAGAGGAGAAGCTCGGTCGCGAGGTGACCGATTTCGAGTTCGCCT
CCTATCTCATGTATCCCAAGGTCTTCACCGATTATGCGGTGGCCTGCGAAACCTACGGCCCCGTCAGCGTACTGCCGACG
CCCGCCTACTTCTACGGCATGGCGCCGGGTGAGGAACTCTTCGCCGAGATCGAGAAGGGCAAGACGCTGGTCATCCTCAA
TCAGGCGCAGGGCGAGATGGACGAGAAGGGCATGGTCAAGATGTTCTTCGAACTGAACGGCCAGCCGCGTTCGATCAAGG
TGCCCGACCGCAACCGCGGCGCTTCGACGGCCATCCGCCGGAAGGCGGAATCCGGCAATGCCGCACATCTCGGCGCGCCG
ATGCCGGGCGTCATCTCCACCGTCGCGGTCGCCAGCGGCCAGTCGGTCAAGGCCGGCGACGTGCTGCTCTCCATCGAGGC
GATGAAAATGGAGACAGCGCTGCATGCGGAGAAGGACGGCGTCGTCGCGGAGGTGCTGGTCAACGCCGGCGATCAGATCG
ATGCCAAGGATCTGCTGATCGTGTTCGGGGAGTAG

Upstream 100 bases:

>100_bases
GGCACCATGTGGTGGCGCTCGCCTTCCGCCTGGGACTGATCTCGTGACTTGATGGTCAAACACCGTCTCCCGCCCCTCCT
GACCGAATGGGTCAGGATTC

Downstream 100 bases:

>100_bases
AGCACCCGCCGCGTCGACGAAAGACCTCCTGACGGTGTAGAGAAGGGCCGCGGGAAGCCGGCCCCTCGGCCGAATTTCAG
ATATCGTAGCTCATCGGCGC

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1184; Mature: 1183

Protein sequence:

>1184_residues
MSRLKLHFIPRLANSLFAGAAFPRVQDHEESDLSISKILVANRSEIAIRVFRAANELGLKTVAIWAEEDKLALHRFKADE
SYQVGRGPHLPRDLGPIESYLSIDEVIRVAKLSGADAIHPGYGLLSESPEFAEACAVNGITFIGPKPETMRQLGNKVAAR
NLAISVGVPVVPATEPLPDDTDEIKRLAEEIGYPVMLKASWGGGGRGMRAIRDPKDLIREVTEAKREAKAAFGKDEVYLE
KLVERARHVESQILGDTHGNVVHLFERDCSIQRRNQKVVERAPAPYLTEAQRQELADYSLKIARATSYIGAGTVEYLMDA
DTGRFYFIEVNPRIQVEHTVTEVVTGIDIVKAQIHILDGFAIGSPESGVPRQEDIRLNGHALQCRITTEDPEQNFIPDYG
RITAYRGATGFGIRLDGGTAYSGAVITRFYDPLLEKVTAWAPNPDEAIKRMVRALREFRIRGVATNLTFLEAIISHPKFH
DNSYTTRFIDTTPELFQQVKRQDRATKLLTYLADVTVNGHPEAKGRPMPSEDIASPLVPFIGDEVKPGTKQRLDQLGPKK
FAEWVKARKEVLITDTTMRDGHQSLLATRMRTYDIARIADTYARALPGLFSLECWGGATFDVSMRFLTEDPWERLAMVRE
GAPNLLLQMLLRGANGVGYKNYPDNVVKYFVRQAAKGGIDVFRVFDCLNWVENMRVSMDAVAEENRICEAAICYTGDILN
SARPKYDLKYYTALAAELEKAGAHMIAVKDMAGLLKPAAARVLFKALKEATDLPIHFHTHDTSGIAAATVLAAVESGVDV
VDAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPEWIRRISFYWEAVRHQYAAFESDLKGPASEVYLHEMPGGQFTNLK
EQARSLGLETRWHEVAQAYADANRMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVENPGKDIAFPESVVSMLKGDLGQP
PGGWPEALQKKALKGEVAYDARPGSLLEDADLDAERKDIEEKLGREVTDFEFASYLMYPKVFTDYAVACETYGPVSVLPT
PAYFYGMAPGEELFAEIEKGKTLVILNQAQGEMDEKGMVKMFFELNGQPRSIKVPDRNRGASTAIRRKAESGNAAHLGAP
MPGVISTVAVASGQSVKAGDVLLSIEAMKMETALHAEKDGVVAEVLVNAGDQIDAKDLLIVFGE

Sequences:

>Translated_1184_residues
MSRLKLHFIPRLANSLFAGAAFPRVQDHEESDLSISKILVANRSEIAIRVFRAANELGLKTVAIWAEEDKLALHRFKADE
SYQVGRGPHLPRDLGPIESYLSIDEVIRVAKLSGADAIHPGYGLLSESPEFAEACAVNGITFIGPKPETMRQLGNKVAAR
NLAISVGVPVVPATEPLPDDTDEIKRLAEEIGYPVMLKASWGGGGRGMRAIRDPKDLIREVTEAKREAKAAFGKDEVYLE
KLVERARHVESQILGDTHGNVVHLFERDCSIQRRNQKVVERAPAPYLTEAQRQELADYSLKIARATSYIGAGTVEYLMDA
DTGRFYFIEVNPRIQVEHTVTEVVTGIDIVKAQIHILDGFAIGSPESGVPRQEDIRLNGHALQCRITTEDPEQNFIPDYG
RITAYRGATGFGIRLDGGTAYSGAVITRFYDPLLEKVTAWAPNPDEAIKRMVRALREFRIRGVATNLTFLEAIISHPKFH
DNSYTTRFIDTTPELFQQVKRQDRATKLLTYLADVTVNGHPEAKGRPMPSEDIASPLVPFIGDEVKPGTKQRLDQLGPKK
FAEWVKARKEVLITDTTMRDGHQSLLATRMRTYDIARIADTYARALPGLFSLECWGGATFDVSMRFLTEDPWERLAMVRE
GAPNLLLQMLLRGANGVGYKNYPDNVVKYFVRQAAKGGIDVFRVFDCLNWVENMRVSMDAVAEENRICEAAICYTGDILN
SARPKYDLKYYTALAAELEKAGAHMIAVKDMAGLLKPAAARVLFKALKEATDLPIHFHTHDTSGIAAATVLAAVESGVDV
VDAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPEWIRRISFYWEAVRHQYAAFESDLKGPASEVYLHEMPGGQFTNLK
EQARSLGLETRWHEVAQAYADANRMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVENPGKDIAFPESVVSMLKGDLGQP
PGGWPEALQKKALKGEVAYDARPGSLLEDADLDAERKDIEEKLGREVTDFEFASYLMYPKVFTDYAVACETYGPVSVLPT
PAYFYGMAPGEELFAEIEKGKTLVILNQAQGEMDEKGMVKMFFELNGQPRSIKVPDRNRGASTAIRRKAESGNAAHLGAP
MPGVISTVAVASGQSVKAGDVLLSIEAMKMETALHAEKDGVVAEVLVNAGDQIDAKDLLIVFGE
>Mature_1183_residues
SRLKLHFIPRLANSLFAGAAFPRVQDHEESDLSISKILVANRSEIAIRVFRAANELGLKTVAIWAEEDKLALHRFKADES
YQVGRGPHLPRDLGPIESYLSIDEVIRVAKLSGADAIHPGYGLLSESPEFAEACAVNGITFIGPKPETMRQLGNKVAARN
LAISVGVPVVPATEPLPDDTDEIKRLAEEIGYPVMLKASWGGGGRGMRAIRDPKDLIREVTEAKREAKAAFGKDEVYLEK
LVERARHVESQILGDTHGNVVHLFERDCSIQRRNQKVVERAPAPYLTEAQRQELADYSLKIARATSYIGAGTVEYLMDAD
TGRFYFIEVNPRIQVEHTVTEVVTGIDIVKAQIHILDGFAIGSPESGVPRQEDIRLNGHALQCRITTEDPEQNFIPDYGR
ITAYRGATGFGIRLDGGTAYSGAVITRFYDPLLEKVTAWAPNPDEAIKRMVRALREFRIRGVATNLTFLEAIISHPKFHD
NSYTTRFIDTTPELFQQVKRQDRATKLLTYLADVTVNGHPEAKGRPMPSEDIASPLVPFIGDEVKPGTKQRLDQLGPKKF
AEWVKARKEVLITDTTMRDGHQSLLATRMRTYDIARIADTYARALPGLFSLECWGGATFDVSMRFLTEDPWERLAMVREG
APNLLLQMLLRGANGVGYKNYPDNVVKYFVRQAAKGGIDVFRVFDCLNWVENMRVSMDAVAEENRICEAAICYTGDILNS
ARPKYDLKYYTALAAELEKAGAHMIAVKDMAGLLKPAAARVLFKALKEATDLPIHFHTHDTSGIAAATVLAAVESGVDVV
DAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPEWIRRISFYWEAVRHQYAAFESDLKGPASEVYLHEMPGGQFTNLKE
QARSLGLETRWHEVAQAYADANRMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVENPGKDIAFPESVVSMLKGDLGQPP
GGWPEALQKKALKGEVAYDARPGSLLEDADLDAERKDIEEKLGREVTDFEFASYLMYPKVFTDYAVACETYGPVSVLPTP
AYFYGMAPGEELFAEIEKGKTLVILNQAQGEMDEKGMVKMFFELNGQPRSIKVPDRNRGASTAIRRKAESGNAAHLGAPM
PGVISTVAVASGQSVKAGDVLLSIEAMKMETALHAEKDGVVAEVLVNAGDQIDAKDLLIVFGE

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1170, Percent_Identity=47.3504273504273, Blast_Score=1026, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1170, Percent_Identity=47.3504273504273, Blast_Score=1026, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1170, Percent_Identity=47.3504273504273, Blast_Score=1026, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=457, Percent_Identity=43.1072210065646, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI65506442, Length=473, Percent_Identity=40.3805496828753, Blast_Score=352, Evalue=1e-96,
Organism=Homo sapiens, GI189095269, Length=467, Percent_Identity=40.8993576017131, Blast_Score=351, Evalue=2e-96,
Organism=Homo sapiens, GI295821183, Length=473, Percent_Identity=40.3805496828753, Blast_Score=351, Evalue=2e-96,
Organism=Homo sapiens, GI38679960, Length=582, Percent_Identity=29.8969072164948, Blast_Score=246, Evalue=9e-65,
Organism=Homo sapiens, GI38679977, Length=582, Percent_Identity=29.8969072164948, Blast_Score=246, Evalue=1e-64,
Organism=Homo sapiens, GI38679967, Length=582, Percent_Identity=29.8969072164948, Blast_Score=246, Evalue=1e-64,
Organism=Homo sapiens, GI38679971, Length=582, Percent_Identity=29.8969072164948, Blast_Score=246, Evalue=1e-64,
Organism=Homo sapiens, GI38679974, Length=582, Percent_Identity=29.8969072164948, Blast_Score=246, Evalue=1e-64,
Organism=Homo sapiens, GI134142062, Length=520, Percent_Identity=31.7307692307692, Blast_Score=242, Evalue=2e-63,
Organism=Escherichia coli, GI1789654, Length=457, Percent_Identity=44.4201312910284, Blast_Score=359, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17562816, Length=1159, Percent_Identity=49.611734253667, Blast_Score=1081, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=466, Percent_Identity=42.7038626609442, Blast_Score=355, Evalue=7e-98,
Organism=Caenorhabditis elegans, GI17567343, Length=465, Percent_Identity=39.3548387096774, Blast_Score=323, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI133931226, Length=502, Percent_Identity=31.2749003984064, Blast_Score=212, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71997168, Length=440, Percent_Identity=30, Blast_Score=201, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71997163, Length=440, Percent_Identity=30, Blast_Score=201, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1164, Percent_Identity=47.1649484536082, Blast_Score=1037, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1162, Percent_Identity=47.7624784853701, Blast_Score=1032, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=454, Percent_Identity=37.0044052863436, Blast_Score=303, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6324343, Length=526, Percent_Identity=31.1787072243346, Blast_Score=228, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6323863, Length=442, Percent_Identity=31.9004524886878, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24652212, Length=1154, Percent_Identity=47.1403812824957, Blast_Score=1026, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1154, Percent_Identity=47.1403812824957, Blast_Score=1026, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1154, Percent_Identity=47.1403812824957, Blast_Score=1026, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1154, Percent_Identity=47.1403812824957, Blast_Score=1026, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1154, Percent_Identity=47.1403812824957, Blast_Score=1026, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1170, Percent_Identity=46.4957264957265, Blast_Score=1021, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1170, Percent_Identity=46.4957264957265, Blast_Score=1021, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1170, Percent_Identity=46.4957264957265, Blast_Score=1021, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1170, Percent_Identity=46.4957264957265, Blast_Score=1021, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1170, Percent_Identity=46.4957264957265, Blast_Score=1021, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=477, Percent_Identity=41.0901467505241, Blast_Score=365, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24651759, Length=421, Percent_Identity=40.6175771971496, Blast_Score=322, Evalue=8e-88,
Organism=Drosophila melanogaster, GI24586458, Length=511, Percent_Identity=29.7455968688845, Blast_Score=220, Evalue=5e-57,
Organism=Drosophila melanogaster, GI161076409, Length=511, Percent_Identity=29.7455968688845, Blast_Score=220, Evalue=5e-57,
Organism=Drosophila melanogaster, GI161076407, Length=511, Percent_Identity=29.7455968688845, Blast_Score=220, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24586460, Length=511, Percent_Identity=29.7455968688845, Blast_Score=220, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 130289; Mature: 130158

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50975 ATP_GRASP ; PS00036 BZIP_BASIC ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLKLHFIPRLANSLFAGAAFPRVQDHEESDLSISKILVANRSEIAIRVFRAANELGLK
CCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCCHHHHHHHHHHHHCCCE
TVAIWAEEDKLALHRFKADESYQVGRGPHLPRDLGPIESYLSIDEVIRVAKLSGADAIHP
EEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GYGLLSESPEFAEACAVNGITFIGPKPETMRQLGNKVAARNLAISVGVPVVPATEPLPDD
CCCCCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCC
TDEIKRLAEEIGYPVMLKASWGGGGRGMRAIRDPKDLIREVTEAKREAKAAFGKDEVYLE
HHHHHHHHHHCCCCEEEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
KLVERARHVESQILGDTHGNVVHLFERDCSIQRRNQKVVERAPAPYLTEAQRQELADYSL
HHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KIARATSYIGAGTVEYLMDADTGRFYFIEVNPRIQVEHTVTEVVTGIDIVKAQIHILDGF
HHHHHHHHHCCCHHHHHEECCCCEEEEEEECCEEEEHHHHHHHHHHHHHHEEEEEEEECE
AIGSPESGVPRQEDIRLNGHALQCRITTEDPEQNFIPDYGRITAYRGATGFGIRLDGGTA
EECCCCCCCCCCCCEEECCEEEEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEECCCCC
YSGAVITRFYDPLLEKVTAWAPNPDEAIKRMVRALREFRIRGVATNLTFLEAIISHPKFH
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DNSYTTRFIDTTPELFQQVKRQDRATKLLTYLADVTVNGHPEAKGRPMPSEDIASPLVPF
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCHHHHHHCCHHH
IGDEVKPGTKQRLDQLGPKKFAEWVKARKEVLITDTTMRDGHQSLLATRMRTYDIARIAD
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
TYARALPGLFSLECWGGATFDVSMRFLTEDPWERLAMVREGAPNLLLQMLLRGANGVGYK
HHHHHCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
NYPDNVVKYFVRQAAKGGIDVFRVFDCLNWVENMRVSMDAVAEENRICEAAICYTGDILN
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHH
SARPKYDLKYYTALAAELEKAGAHMIAVKDMAGLLKPAAARVLFKALKEATDLPIHFHTH
CCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
DTSGIAAATVLAAVESGVDVVDAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPEWIRR
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHH
ISFYWEAVRHQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHEVAQAYA
HHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHH
DANRMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVENPGKDIAFPESVVSMLKGDLGQP
HHHHHHHHHEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCC
PGGWPEALQKKALKGEVAYDARPGSLLEDADLDAERKDIEEKLGREVTDFEFASYLMYPK
CCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
VFTDYAVACETYGPVSVLPTPAYFYGMAPGEELFAEIEKGKTLVILNQAQGEMDEKGMVK
HHHHHHHHHCCCCCCEECCCCHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCEE
MFFELNGQPRSIKVPDRNRGASTAIRRKAESGNAAHLGAPMPGVISTVAVASGQSVKAGD
EEEEECCCCCEEECCCCCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCC
VLLSIEAMKMETALHAEKDGVVAEVLVNAGDQIDAKDLLIVFGE
EEEEEHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
SRLKLHFIPRLANSLFAGAAFPRVQDHEESDLSISKILVANRSEIAIRVFRAANELGLK
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCCHHHHHHHHHHHHCCCE
TVAIWAEEDKLALHRFKADESYQVGRGPHLPRDLGPIESYLSIDEVIRVAKLSGADAIHP
EEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GYGLLSESPEFAEACAVNGITFIGPKPETMRQLGNKVAARNLAISVGVPVVPATEPLPDD
CCCCCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCC
TDEIKRLAEEIGYPVMLKASWGGGGRGMRAIRDPKDLIREVTEAKREAKAAFGKDEVYLE
HHHHHHHHHHCCCCEEEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
KLVERARHVESQILGDTHGNVVHLFERDCSIQRRNQKVVERAPAPYLTEAQRQELADYSL
HHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KIARATSYIGAGTVEYLMDADTGRFYFIEVNPRIQVEHTVTEVVTGIDIVKAQIHILDGF
HHHHHHHHHCCCHHHHHEECCCCEEEEEEECCEEEEHHHHHHHHHHHHHHEEEEEEEECE
AIGSPESGVPRQEDIRLNGHALQCRITTEDPEQNFIPDYGRITAYRGATGFGIRLDGGTA
EECCCCCCCCCCCCEEECCEEEEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEECCCCC
YSGAVITRFYDPLLEKVTAWAPNPDEAIKRMVRALREFRIRGVATNLTFLEAIISHPKFH
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DNSYTTRFIDTTPELFQQVKRQDRATKLLTYLADVTVNGHPEAKGRPMPSEDIASPLVPF
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCHHHHHHCCHHH
IGDEVKPGTKQRLDQLGPKKFAEWVKARKEVLITDTTMRDGHQSLLATRMRTYDIARIAD
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
TYARALPGLFSLECWGGATFDVSMRFLTEDPWERLAMVREGAPNLLLQMLLRGANGVGYK
HHHHHCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
NYPDNVVKYFVRQAAKGGIDVFRVFDCLNWVENMRVSMDAVAEENRICEAAICYTGDILN
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHH
SARPKYDLKYYTALAAELEKAGAHMIAVKDMAGLLKPAAARVLFKALKEATDLPIHFHTH
CCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
DTSGIAAATVLAAVESGVDVVDAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPEWIRR
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHH
ISFYWEAVRHQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHEVAQAYA
HHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHH
DANRMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVENPGKDIAFPESVVSMLKGDLGQP
HHHHHHHHHEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCC
PGGWPEALQKKALKGEVAYDARPGSLLEDADLDAERKDIEEKLGREVTDFEFASYLMYPK
CCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
VFTDYAVACETYGPVSVLPTPAYFYGMAPGEELFAEIEKGKTLVILNQAQGEMDEKGMVK
HHHHHHHHHCCCCCCEECCCCHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCEE
MFFELNGQPRSIKVPDRNRGASTAIRRKAESGNAAHLGAPMPGVISTVAVASGQSVKAGD
EEEEECCCCCEEECCCCCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCC
VLLSIEAMKMETALHAEKDGVVAEVLVNAGDQIDAKDLLIVFGE
EEEEEHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]