BacMap

Definition	Sinorhizobium medicae WSM419 chromosome, complete genome.
Accession	NC_009636
Length	3,781,904

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The map label for this gene is phbB [H]

Identifier: 150398310

GI number: 150398310

Start: 3265713

End: 3266438

Strand: Reverse

Name: phbB [H]

Synonym: Smed_3116

Alternate gene names: 150398310

Gene position: 3266438-3265713 (Counterclockwise)

Preceding gene: 150398311

Following gene: 150398309

Centisome position: 86.37

GC content: 60.33

Gene sequence:

>726_bases
ATGAGCAGGGTAGCATTGGTCACGGGCGGATCGCGCGGCATCGGCGCGGCAATCGCCATCGCGCTGAAGGCAGCGGGCTA
CAAGGTGGCTGCGAATTACGCGGGCAATGACGAAAAAGCCCAGGCTTTCAAACAGGAGACCGGCATCCCCGTTTATAAGT
GGGATGTCTCGAGTTACGAGGCCTGCGTCGACGGCATTGCCAGGGTCGAGGCGGACCTGGGGCCGGTAGATATCCTCGTC
AACAATGCCGGCATCACACGTGACGCGATGTTCCACAAGATGACGCCGCAACAATGGGGCGAAGTCATAGGCACGAATCT
CACCGGCGTTTTCAACATGACGCATCCGATCTGGTCGGGGATGCGCGACCGCGGGTTCGGCCGCATCGTCAACATCTCGT
CGATCAACGGTCAGAAGGGGCAGATGGGACAGGCGAACTATTCTGCCGCCAAGGCCGGCGATCTCGGCTTCACCAAGGCG
CTTGCTCAGGAAGGGGCAGCGAAGGGAATCACGGTAAATGCCATTTGCCCGGGTTATATCGGCACGGAAATGGTGCTCGC
CGTACCGGAGAAGGTGCTTAACGAGCGGATCATCCCGCAGATACCCGTCGGCCGCCTGGGCGAACCGGAAGAAGTCGCGC
GATGCGTCGTGTTCCTCGTGTCGGATGATGCCGGCTTCATTACCGGTTCCACGATCTCGGCCAATGGTGGCCAGTACTTC
GCCTGA

Upstream 100 bases:

>100_bases
GCCGGGCGACTTCCAGATCCGGATATGCACAGGCGGCCCGGGCTCCGGGCCGCGGAAGGACGATTTTCGCCAATTTGGCT
TAACAGAGCGGGAGGCACTA

Downstream 100 bases:

>100_bases
GACTTTTTTCTGACCGACTGTGTTCCCGCCGCCCTTTGCGGCGCCGGATTTTTTTCGACGGGCATTCGGCGGCTGGACCA
CGGTTTTTTGGGTTGGATCG

Product: acetoacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSRVALVTGGSRGIGAAIAIALKAAGYKVAANYAGNDEKAQAFKQETGIPVYKWDVSSYEACVDGIARVEADLGPVDILV
NNAGITRDAMFHKMTPQQWGEVIGTNLTGVFNMTHPIWSGMRDRGFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKA
LAQEGAAKGITVNAICPGYIGTEMVLAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLVSDDAGFITGSTISANGGQYF
A

Sequences:

>Translated_241_residues
MSRVALVTGGSRGIGAAIAIALKAAGYKVAANYAGNDEKAQAFKQETGIPVYKWDVSSYEACVDGIARVEADLGPVDILV
NNAGITRDAMFHKMTPQQWGEVIGTNLTGVFNMTHPIWSGMRDRGFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKA
LAQEGAAKGITVNAICPGYIGTEMVLAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLVSDDAGFITGSTISANGGQYF
A
>Mature_240_residues
SRVALVTGGSRGIGAAIAIALKAAGYKVAANYAGNDEKAQAFKQETGIPVYKWDVSSYEACVDGIARVEADLGPVDILVN
NAGITRDAMFHKMTPQQWGEVIGTNLTGVFNMTHPIWSGMRDRGFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKAL
AQEGAAKGITVNAICPGYIGTEMVLAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLVSDDAGFITGSTISANGGQYFA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=38.0952380952381, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=38.0753138075314, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI4504505, Length=235, Percent_Identity=33.1914893617021, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=31.9502074688797, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI4758504, Length=247, Percent_Identity=33.1983805668016, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=34.5528455284553, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=33.9920948616601, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=29.7071129707113, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=30.6451612903226, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI66933014, Length=242, Percent_Identity=29.3388429752066, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI83715985, Length=247, Percent_Identity=31.1740890688259, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542939, Length=242, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI59889578, Length=217, Percent_Identity=29.9539170506912, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=30.4878048780488, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.6, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503817, Length=222, Percent_Identity=29.2792792792793, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI226371731, Length=192, Percent_Identity=33.8541666666667, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=31.9371727748691, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=30, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4503301, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI142976729, Length=218, Percent_Identity=27.0642201834862, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40807363, Length=190, Percent_Identity=27.3684210526316, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=44.4897959183673, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=37.5510204081633, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=31.9502074688797, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=33.976833976834, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=32.2314049586777, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=31.9502074688797, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=29.9595141700405, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786812, Length=241, Percent_Identity=31.1203319502075, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=31.3559322033898, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=31.0077519379845, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=27.1966527196653, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=30, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=33.1491712707182, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787526, Length=246, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=42.0833333333333, Blast_Score=164, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=40.5857740585774, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17568967, Length=233, Percent_Identity=34.7639484978541, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=32.2314049586777, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=33.0677290836653, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=31.9838056680162, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=30.3643724696356, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=232, Percent_Identity=28.8793103448276, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=232, Percent_Identity=28.8793103448276, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=29.8039215686275, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=29.5546558704453, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=32.1428571428571, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=251, Percent_Identity=29.8804780876494, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=30.3149606299213, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=29.2307692307692, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=28.0769230769231, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=30.6201550387597, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=26.3358778625954, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=28.7937743190661, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=31.3953488372093, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=28.2945736434109, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=27.0408163265306, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=260, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=27.2373540856031, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=27.6264591439689, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=31.1538461538462, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=30.2083333333333, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=27.5193798449612, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=27.3076923076923, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=35.3448275862069, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=26.8292682926829, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320089, Length=205, Percent_Identity=31.219512195122, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=28.7179487179487, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=39.0041493775934, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=33.7349397590361, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=31.8367346938775, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=33.596837944664, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=33.8842975206612, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859837, Length=230, Percent_Identity=32.6086956521739, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=33.195020746888, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=32.4, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=32.9059829059829, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=31.7708333333333, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=29.9145299145299, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649181, Length=187, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364494, Length=209, Percent_Identity=33.4928229665072, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=31.5217391304348, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641232, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641388, Length=238, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=31.7365269461078, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221331218, Length=236, Percent_Identity=30.0847457627119, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665243, Length=236, Percent_Identity=30.0847457627119, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=167, Percent_Identity=29.3413173652695, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571387, Length=253, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221331216, Length=237, Percent_Identity=29.1139240506329, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665247, Length=237, Percent_Identity=29.1139240506329, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007238, Length=175, Percent_Identity=32.5714285714286, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007234, Length=200, Percent_Identity=30, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 25328; Mature: 25197

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVALVTGGSRGIGAAIAIALKAAGYKVAANYAGNDEKAQAFKQETGIPVYKWDVSSYE
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCHHHH
ACVDGIARVEADLGPVDILVNNAGITRDAMFHKMTPQQWGEVIGTNLTGVFNMTHPIWSG
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHCCCCEEEEECCCHHHCC
MRDRGFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKALAQEGAAKGITVNAICPGYI
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCC
GTEMVLAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLVSDDAGFITGSTISANGGQYF
CHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEEEECCCCEEECCEEECCCCCCC
A
C
>Mature Secondary Structure 
SRVALVTGGSRGIGAAIAIALKAAGYKVAANYAGNDEKAQAFKQETGIPVYKWDVSSYE
CEEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCHHHH
ACVDGIARVEADLGPVDILVNNAGITRDAMFHKMTPQQWGEVIGTNLTGVFNMTHPIWSG
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHCCCCEEEEECCCHHHCC
MRDRGFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKALAQEGAAKGITVNAICPGYI
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCC
GTEMVLAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLVSDDAGFITGSTISANGGQYF
CHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEEEECCCCEEECCEEECCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7582015; 11481430 [H]