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The map label for this gene is yvrH [H]

Identifier: 150398250

GI number: 150398250

Start: 3205841

End: 3206602

Strand: Reverse

Name: yvrH [H]

Synonym: Smed_3056

Alternate gene names: 150398250

Gene position: 3206602-3205841 (Counterclockwise)

Preceding gene: 150398252

Following gene: 150398249

Centisome position: 84.79

GC content: 58.4

Gene sequence:

>762_bases
ATGCGGCAGCGACCGCCGCGCTTGCCAAGCGTGGCATTTGAGATAGTTTTGGATCAGGAAGCAAACAGGAATTGTCCCAT
GGCGACTCGCACCATCCTCCTTGTCGACGACGACGATGATCTGCGTGAGACCTTGATAGAGCAGCTCTCCCTTTACGAAG
AGTTCGATCTTTTGCAGGAAGCGACCGCCGGTAAAGGCATTCAGACCGCTCGTGCCCGCCAGGTCGATCTCCTGATCATG
GATGTCGGTCTGCCGGACATGGATGGGCGCGAGGCGGTGAAGCTTTTGCGCAAAGGCGGCTTCAAGGCCCCGATCATCAT
GCTCACCGGCCATGACACGGACTCCGATACGATTCTCGGCCTCGAGGCCGGCGCCAACGACTATGTGACGAAGCCCTTCC
GCTTCGCGGTTCTGCTGGCCCGCATCCGCGCCCAGCTTCGCCAGCACGAGCAGAGCGAAGACGCGACCTTCAATGTCGGC
CCCTATACCTTCAAGCCGAGCCAGAAGCTGCTTACCATGGAGAACGGGCAGAAGATCAGGCTGACGGAAAAGGAAGCCGC
GATCATCCGCTATCTCTATCGTGCCGACCAGAAGGTGGTTACCCGCGACGTGCTCCTGGAAGAGGTCTGGGGTTACAATT
CCGGCGTCACCACCCATACTCTTGAGACGCATGTCTACCGGCTCCGCCAGAAAATCGAGCGCGACCCTTCCAATGCCGAG
ATTTTGGTGACAGAAAACGGCGGCTACAAGATCGTTCCGTAA

Upstream 100 bases:

>100_bases
TGGCTAACGCGCCTGCGTTTCACCGGAAGCGCGAAGGTCGCTTTAGCCAGTCTCAGTTACCACATGCTTCTATCCTACAT
CGGCCAGGATTTAGCGAAAC

Downstream 100 bases:

>100_bases
ATGGGAGATCGCTGCGTGACCGGGGGAGATTTGCCGCTTGGCGCTCAATGACGACATTGCGCTCCTGTCCAATGTTTCGC
TCTTCGCTGACATCGGCGAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRQRPPRLPSVAFEIVLDQEANRNCPMATRTILLVDDDDDLRETLIEQLSLYEEFDLLQEATAGKGIQTARARQVDLLIM
DVGLPDMDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQHEQSEDATFNVG
PYTFKPSQKLLTMENGQKIRLTEKEAAIIRYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAE
ILVTENGGYKIVP

Sequences:

>Translated_253_residues
MRQRPPRLPSVAFEIVLDQEANRNCPMATRTILLVDDDDDLRETLIEQLSLYEEFDLLQEATAGKGIQTARARQVDLLIM
DVGLPDMDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQHEQSEDATFNVG
PYTFKPSQKLLTMENGQKIRLTEKEAAIIRYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAE
ILVTENGGYKIVP
>Mature_253_residues
MRQRPPRLPSVAFEIVLDQEANRNCPMATRTILLVDDDDDLRETLIEQLSLYEEFDLLQEATAGKGIQTARARQVDLLIM
DVGLPDMDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQHEQSEDATFNVG
PYTFKPSQKLLTMENGQKIRLTEKEAAIIRYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAE
ILVTENGGYKIVP

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.0807174887892, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=33.4841628959276, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=32.8888888888889, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=32.8888888888889, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=31.304347826087, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789402, Length=205, Percent_Identity=29.2682926829268, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787375, Length=174, Percent_Identity=32.183908045977, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=28.3842794759825, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=26.1061946902655, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=34.4497607655502, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=27.6595744680851, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=27.3913043478261, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787229, Length=197, Percent_Identity=29.9492385786802, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=27.9661016949153, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28727; Mature: 28727

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQRPPRLPSVAFEIVLDQEANRNCPMATRTILLVDDDDDLRETLIEQLSLYEEFDLLQE
CCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
ATAGKGIQTARARQVDLLIMDVGLPDMDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILG
HHCCCCCCHHHHCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEE
LEAGANDYVTKPFRFAVLLARIRAQLRQHEQSEDATFNVGPYTFKPSQKLLTMENGQKIR
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEECCCCEEEEECCCCEEE
LTEKEAAIIRYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAE
EEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCE
ILVTENGGYKIVP
EEEECCCCEEECC
>Mature Secondary Structure
MRQRPPRLPSVAFEIVLDQEANRNCPMATRTILLVDDDDDLRETLIEQLSLYEEFDLLQE
CCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
ATAGKGIQTARARQVDLLIMDVGLPDMDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILG
HHCCCCCCHHHHCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEE
LEAGANDYVTKPFRFAVLLARIRAQLRQHEQSEDATFNVGPYTFKPSQKLLTMENGQKIR
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEECCCCEEEEECCCCEEE
LTEKEAAIIRYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAE
EEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCE
ILVTENGGYKIVP
EEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]