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The map label for this gene is visC [C]

Identifier: 150398242

GI number: 150398242

Start: 3196379

End: 3197593

Strand: Reverse

Name: visC [C]

Synonym: Smed_3048

Alternate gene names: 150398242

Gene position: 3197593-3196379 (Counterclockwise)

Preceding gene: 150398249

Following gene: 150398236

Centisome position: 84.55

GC content: 65.1

Gene sequence:

>1215_bases
ATGATCGATGTATTGATTGCCGGGGGCGGTTATGTCGGCCTCTCGCTTGCGGTATCGCTGAAAAAGGCGGCACCCCATCT
CGATGTCATGGTTGTCGATGCCGCGCCGGAAGGCGCCTGGAAGAAGGACGAGCGGGCGTCGGCCATCGCGTCGGCCGCCG
AGCGGATGCTCGAGATCCTCGGCGTGTGGCAGGCGATCGCGCCGGAAGCGGAGCCGATCCTGAGGATGGTGATCACCGAT
TCGAAGACGGCGGATCCCGTGCGCCCGGTCTTCCTCACATTCGAGGGCGATGGCGGTGACGGCCGGCCCTTCGCCCACAT
GGTACCGAACACGGCCCTCGTCGGTGCGCTTCGCCGCGCCTGTGACGAACTCGGCGTTTCGGTCCGGCAGTCGACCCTGG
TGGAGAGTTTCAAGACCGGAGATCATTCCGTTGCCGTTACGCTCGCTGGAGGGGAGGCGGTCGAGTCGCGGCTGCTGGTC
GCCTGCGACGGCGTTCGCTCCAGGCTGCGCGAGGCGGCGGGCATCAAGGTCGTTGAATTCGATTACGGCCAGTCGGGCAT
CGTCACGACCGTCGAGCACGAGCGGCCGCACGGCGGAACGGCGGAGGAGCATTTCCTGCCGGCCGGCCCTTTCGCGACGC
TGCCGCTCAAGGATAATCGCTCCTCGCTCGTCTGGACGGAGAGCACCTATGATGCAGAGCGCCTGGTCAAGGAAGATGAT
TTCATCTTCGAGGAGGAGTTGGAGCGTCGCTTCGGCCATAAGCTTGGCCGCCTCAAGGTGGTGGGCGGACGGCGCGCCTT
CCCGCTCGGCCTCACGCTTGCGCGGGATTTCGTCGCGTCGCGTTTCGCGCTCGCCGGGGATGCCGCACATGGGATACACC
CGATTTCCGGACAGGGGCTCAACCTCGGCTTCAAGGACGTCGCGGCTCTTGCCGAAACGATCGTCGAAGCGGACCGCCTC
GGCCTCGATATCGGCTCACTCGCCGTTCTCGAGCGTTATCAGACGTGGAGGCGTTTCGATACCTTCCGGATGGGCGTTAC
GACGGACGTCCTCAACAGGCTCTTCTCCAACGACATCATGCCGGTGCGGGTCGCGCGCGATTTCGGACTCGGCGTCGTGG
ACCGCATGCCGTCGCTCAAGAAATTCTTCATCCGCCAGGCGGCGGGTGCGCCCGGCAGAAACGATCCGCGGTTGCTCGCC
GGCGAGCCGATTTGA

Upstream 100 bases:

>100_bases
CGGTGAGGCGCGACATCTTGGCGGTCTCCTATGGTAGGAACGGCGATGGCATTGATCTATATAGGCACGAGATGATGCTC
AAGTGCGGGAGACGAGGCGG

Downstream 100 bases:

>100_bases
GATAATTTGAATTCTTTCTCGGTCTGCGGCAGCGTCCGCTCCGAACATTATTCTTCGATCTTGCGTGCCTCCGAGATCAG
CATGATCGGCACGCCGTCGC

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MIDVLIAGGGYVGLSLAVSLKKAAPHLDVMVVDAAPEGAWKKDERASAIASAAERMLEILGVWQAIAPEAEPILRMVITD
SKTADPVRPVFLTFEGDGGDGRPFAHMVPNTALVGALRRACDELGVSVRQSTLVESFKTGDHSVAVTLAGGEAVESRLLV
ACDGVRSRLREAAGIKVVEFDYGQSGIVTTVEHERPHGGTAEEHFLPAGPFATLPLKDNRSSLVWTESTYDAERLVKEDD
FIFEEELERRFGHKLGRLKVVGGRRAFPLGLTLARDFVASRFALAGDAAHGIHPISGQGLNLGFKDVAALAETIVEADRL
GLDIGSLAVLERYQTWRRFDTFRMGVTTDVLNRLFSNDIMPVRVARDFGLGVVDRMPSLKKFFIRQAAGAPGRNDPRLLA
GEPI

Sequences:

>Translated_404_residues
MIDVLIAGGGYVGLSLAVSLKKAAPHLDVMVVDAAPEGAWKKDERASAIASAAERMLEILGVWQAIAPEAEPILRMVITD
SKTADPVRPVFLTFEGDGGDGRPFAHMVPNTALVGALRRACDELGVSVRQSTLVESFKTGDHSVAVTLAGGEAVESRLLV
ACDGVRSRLREAAGIKVVEFDYGQSGIVTTVEHERPHGGTAEEHFLPAGPFATLPLKDNRSSLVWTESTYDAERLVKEDD
FIFEEELERRFGHKLGRLKVVGGRRAFPLGLTLARDFVASRFALAGDAAHGIHPISGQGLNLGFKDVAALAETIVEADRL
GLDIGSLAVLERYQTWRRFDTFRMGVTTDVLNRLFSNDIMPVRVARDFGLGVVDRMPSLKKFFIRQAAGAPGRNDPRLLA
GEPI
>Mature_404_residues
MIDVLIAGGGYVGLSLAVSLKKAAPHLDVMVVDAAPEGAWKKDERASAIASAAERMLEILGVWQAIAPEAEPILRMVITD
SKTADPVRPVFLTFEGDGGDGRPFAHMVPNTALVGALRRACDELGVSVRQSTLVESFKTGDHSVAVTLAGGEAVESRLLV
ACDGVRSRLREAAGIKVVEFDYGQSGIVTTVEHERPHGGTAEEHFLPAGPFATLPLKDNRSSLVWTESTYDAERLVKEDD
FIFEEELERRFGHKLGRLKVVGGRRAFPLGLTLARDFVASRFALAGDAAHGIHPISGQGLNLGFKDVAALAETIVEADRL
GLDIGSLAVLERYQTWRRFDTFRMGVTTDVLNRLFSNDIMPVRVARDFGLGVVDRMPSLKKFFIRQAAGAPGRNDPRLLA
GEPI

Specific function: Not Yet Known. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=404, Percent_Identity=29.9504950495049, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI32967307, Length=343, Percent_Identity=32.0699708454811, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1786883, Length=393, Percent_Identity=34.0966921119593, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1789273, Length=399, Percent_Identity=32.8320802005013, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1789274, Length=400, Percent_Identity=33.75, Blast_Score=189, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI25146631, Length=434, Percent_Identity=29.7235023041475, Blast_Score=174, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6321694, Length=295, Percent_Identity=28.8135593220339, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI19920760, Length=427, Percent_Identity=27.1662763466042, Blast_Score=134, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43705; Mature: 43705

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDVLIAGGGYVGLSLAVSLKKAAPHLDVMVVDAAPEGAWKKDERASAIASAAERMLEIL
CEEEEEECCCEEEHHHEEEHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GVWQAIAPEAEPILRMVITDSKTADPVRPVFLTFEGDGGDGRPFAHMVPNTALVGALRRA
HHHHHHCCCHHHHEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHH
CDELGVSVRQSTLVESFKTGDHSVAVTLAGGEAVESRLLVACDGVRSRLREAAGIKVVEF
HHHHCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHCCEEEEEHHHHHHHHHHHCCEEEEE
DYGQSGIVTTVEHERPHGGTAEEHFLPAGPFATLPLKDNRSSLVWTESTYDAERLVKEDD
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHCCC
FIFEEELERRFGHKLGRLKVVGGRRAFPLGLTLARDFVASRFALAGDAAHGIHPISGQGL
CHHHHHHHHHHCHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
NLGFKDVAALAETIVEADRLGLDIGSLAVLERYQTWRRFDTFRMGVTTDVLNRLFSNDIM
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCE
PVRVARDFGLGVVDRMPSLKKFFIRQAAGAPGRNDPRLLAGEPI
EEEEECCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCCEECCCCC
>Mature Secondary Structure
MIDVLIAGGGYVGLSLAVSLKKAAPHLDVMVVDAAPEGAWKKDERASAIASAAERMLEIL
CEEEEEECCCEEEHHHEEEHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GVWQAIAPEAEPILRMVITDSKTADPVRPVFLTFEGDGGDGRPFAHMVPNTALVGALRRA
HHHHHHCCCHHHHEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHH
CDELGVSVRQSTLVESFKTGDHSVAVTLAGGEAVESRLLVACDGVRSRLREAAGIKVVEF
HHHHCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHCCEEEEEHHHHHHHHHHHCCEEEEE
DYGQSGIVTTVEHERPHGGTAEEHFLPAGPFATLPLKDNRSSLVWTESTYDAERLVKEDD
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHCCC
FIFEEELERRFGHKLGRLKVVGGRRAFPLGLTLARDFVASRFALAGDAAHGIHPISGQGL
CHHHHHHHHHHCHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
NLGFKDVAALAETIVEADRLGLDIGSLAVLERYQTWRRFDTFRMGVTTDVLNRLFSNDIM
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCE
PVRVARDFGLGVVDRMPSLKKFFIRQAAGAPGRNDPRLLAGEPI
EEEEECCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]