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The map label for this gene is lrp [C]

Identifier: 150398116

GI number: 150398116

Start: 3063580

End: 3064044

Strand: Reverse

Name: lrp [C]

Synonym: Smed_2919

Alternate gene names: 150398116

Gene position: 3064044-3063580 (Counterclockwise)

Preceding gene: 150398118

Following gene: 150398110

Centisome position: 81.02

GC content: 63.01

Gene sequence:

>465_bases
ATGTTCGGCAATTCGCCGACGAAAGCCGACGATATGCAGGTAACCGACAAAGACCGCGAACTCCTCGCCATCCTGAGCGA
GAACGCTCGCATGTCCACGGCGACGATCGCCCGGCGCCTCGGCCTGTCGCGCACGACCGTACAGGCCCGAATCGAACGGC
TGGAGCGTGAGGGGGTGATCGCGGGCTACGGCGTGCGGCTCTCGGAAAGCTACGAGAAGGGTCTCGTGCGAGCGCATGTC
CTGATCACCATCGCGCCCCGGGCGCTGAGCCGGGTCACGCCGGAACTTGCCGCCATTGGCGAAATCCGCATGCTGCATTC
GGTCAGCGGCAGTTTCGATCTGATCGCGGTCGTCGCGGCTTCCTCGATCAGCGAACTGGATCTGCTGATCGACCGCATCG
GCGAGATCGAGGGTGTCGAAAAGACCCTGTCGTCGATCATTCTTTCGACCCGCATCGACCGTTGA

Upstream 100 bases:

>100_bases
CTTTCATTCTAAAATTCCCCGGGGCATGAGCCTTTTCCACCGCCATTGTCGCGCTGCCACCTATTGATTTGAAGCTTCGA
TATGGCTAAATCGTCGGCTT

Downstream 100 bases:

>100_bases
ACGCCGGCTCCTCACTGTGCCGGAGTAGCGGGTTGCGGGCCCGGCCGTGGCCAGGCGCTGGGACCCTGGATGAAGGAAAC
GCTCGCACCCTCGCCCGGCG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MFGNSPTKADDMQVTDKDRELLAILSENARMSTATIARRLGLSRTTVQARIERLEREGVIAGYGVRLSESYEKGLVRAHV
LITIAPRALSRVTPELAAIGEIRMLHSVSGSFDLIAVVAASSISELDLLIDRIGEIEGVEKTLSSIILSTRIDR

Sequences:

>Translated_154_residues
MFGNSPTKADDMQVTDKDRELLAILSENARMSTATIARRLGLSRTTVQARIERLEREGVIAGYGVRLSESYEKGLVRAHV
LITIAPRALSRVTPELAAIGEIRMLHSVSGSFDLIAVVAASSISELDLLIDRIGEIEGVEKTLSSIILSTRIDR
>Mature_154_residues
MFGNSPTKADDMQVTDKDRELLAILSENARMSTATIARRLGLSRTTVQARIERLEREGVIAGYGVRLSESYEKGLVRAHV
LITIAPRALSRVTPELAAIGEIRMLHSVSGSFDLIAVVAASSISELDLLIDRIGEIEGVEKTLSSIILSTRIDR

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=135, Percent_Identity=30.3703703703704, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR013249
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 16804; Mature: 16804

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGNSPTKADDMQVTDKDRELLAILSENARMSTATIARRLGLSRTTVQARIERLEREGVI
CCCCCCCCCCCCEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCE
AGYGVRLSESYEKGLVRAHVLITIAPRALSRVTPELAAIGEIRMLHSVSGSFDLIAVVAA
EECCEEEHHHHHHHHHHHHHEEEECHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
SSISELDLLIDRIGEIEGVEKTLSSIILSTRIDR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFGNSPTKADDMQVTDKDRELLAILSENARMSTATIARRLGLSRTTVQARIERLEREGVI
CCCCCCCCCCCCEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCE
AGYGVRLSESYEKGLVRAHVLITIAPRALSRVTPELAAIGEIRMLHSVSGSFDLIAVVAA
EECCEEEHHHHHHHHHHHHHEEEECHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
SSISELDLLIDRIGEIEGVEKTLSSIILSTRIDR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]