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The map label for this gene is frlB [H]

Identifier: 150398042

GI number: 150398042

Start: 2970719

End: 2971732

Strand: Direct

Name: frlB [H]

Synonym: Smed_2844

Alternate gene names: 150398042

Gene position: 2970719-2971732 (Clockwise)

Preceding gene: 150398040

Following gene: 150398043

Centisome position: 78.55

GC content: 61.14

Gene sequence:

>1014_bases
ATGCTGAATTTTGACGAACAGAGATTCCTTCGCATCCAGTCGGGAGCCGTTGCCCTGCGCAAACGCCTGGACGACGTCAT
CATCTCCTGCCTTGAAAAAGGCGCGGAGAACATCTTCTTCCTCGGGACGGGCGGCGCCGCCATCCTCATGCAGCCTGCCG
CCCAATTGCTGCAACGCAGGTCGCGCTTCCCGGCCTTCATCGACATGCCTGCCGAACTCTTCCTTACCGGTTCGGCGAAC
CTGACGGAAAAGTCGATCGTCGTCATTCCCTCCCTCTCCGGCACGACCAAGGAAAGTGTGGCTCTGCTGGCAAAGGCCAA
GGAGGCCGGCGCGACAGTCCTGACGCTCGTCGGACACGCGGAAACGCCGCTCGGCAAAGGGGCCGATCATGCCTTCGTCA
ACTTCGCCGAAGACGACACGTCCTGCGAGTCCTTCTATCTGCAATCCCTGTTCATCGCCCTTTCGATCATGCGGCACCGC
GGCGAGATCGAAAACTACGAGCAGATCGCAGCTGAACTGGAAACCCTCCCGCAGCTCCTCCTGGAGGTAAAGCGCGCCTA
TGAGGATAAGGCTGAAGCCTTCGCCCGTGTTCTGGCCGGTTCGGACTACCACATCATCACGGGCGCCGGTAACGTCTGGC
CGGAGGCCTTCTACTATGGCATGTGCATCCTCGAAGAGATGCAGTGGATCCGCACGCGCCCTGTGCATGCCTCGGACTTT
TTCCATGGAACGCTGGAACTCGTGGAAAAGGGCGTCAGCGTCATCCTCTTCAAGGGCGAAGACGCGCTGCGGCCGCTCGG
CGATCGTGTGCAGAATTTCGCCCCCAACTACACGGACAGACTGACGGTACTCGACACTGCGGACTTCGCGCTCCCGGGCG
TTTCCGACGAGGTGCGCGGCCTCGTGTCGCCGATCGTGCTCGCAAGCGTGCTCGAACGCATCAGCGCGCATCTGGAAGTC
ATGCGCGATCACCCGCTGACGACGCGGCGCTACTACAAGCGCGTGGCCTATTGA

Upstream 100 bases:

>100_bases
GATATTGCCCTTGACATCGTTGAGCAATGTTGTCAGTTGTCTTACAACATTGCCGGAATATCGAGCGCCGGCAGTCGCCA
CCACCTGTCGAGAGAGAACC

Downstream 100 bases:

>100_bases
ACAGAGACCTCCAAAGCGGAATGCTCCGAGACGACCGCGAATGTCTCCACATTCGCGGTCGCCCGTGCAAGACAAGAGAA
CGCCATGACCAAATTTCGCT

Product: sugar isomerase (SIS)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLNFDEQRFLRIQSGAVALRKRLDDVIISCLEKGAENIFFLGTGGAAILMQPAAQLLQRRSRFPAFIDMPAELFLTGSAN
LTEKSIVVIPSLSGTTKESVALLAKAKEAGATVLTLVGHAETPLGKGADHAFVNFAEDDTSCESFYLQSLFIALSIMRHR
GEIENYEQIAAELETLPQLLLEVKRAYEDKAEAFARVLAGSDYHIITGAGNVWPEAFYYGMCILEEMQWIRTRPVHASDF
FHGTLELVEKGVSVILFKGEDALRPLGDRVQNFAPNYTDRLTVLDTADFALPGVSDEVRGLVSPIVLASVLERISAHLEV
MRDHPLTTRRYYKRVAY

Sequences:

>Translated_337_residues
MLNFDEQRFLRIQSGAVALRKRLDDVIISCLEKGAENIFFLGTGGAAILMQPAAQLLQRRSRFPAFIDMPAELFLTGSAN
LTEKSIVVIPSLSGTTKESVALLAKAKEAGATVLTLVGHAETPLGKGADHAFVNFAEDDTSCESFYLQSLFIALSIMRHR
GEIENYEQIAAELETLPQLLLEVKRAYEDKAEAFARVLAGSDYHIITGAGNVWPEAFYYGMCILEEMQWIRTRPVHASDF
FHGTLELVEKGVSVILFKGEDALRPLGDRVQNFAPNYTDRLTVLDTADFALPGVSDEVRGLVSPIVLASVLERISAHLEV
MRDHPLTTRRYYKRVAY
>Mature_337_residues
MLNFDEQRFLRIQSGAVALRKRLDDVIISCLEKGAENIFFLGTGGAAILMQPAAQLLQRRSRFPAFIDMPAELFLTGSAN
LTEKSIVVIPSLSGTTKESVALLAKAKEAGATVLTLVGHAETPLGKGADHAFVNFAEDDTSCESFYLQSLFIALSIMRHR
GEIENYEQIAAELETLPQLLLEVKRAYEDKAEAFARVLAGSDYHIITGAGNVWPEAFYYGMCILEEMQWIRTRPVHASDF
FHGTLELVEKGVSVILFKGEDALRPLGDRVQNFAPNYTDRLTVLDTADFALPGVSDEVRGLVSPIVLASVLERISAHLEV
MRDHPLTTRRYYKRVAY

Specific function: Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Escherichia coli, GI87082251, Length=302, Percent_Identity=23.1788079470199, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 37398; Mature: 37398

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFDEQRFLRIQSGAVALRKRLDDVIISCLEKGAENIFFLGTGGAAILMQPAAQLLQRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
SRFPAFIDMPAELFLTGSANLTEKSIVVIPSLSGTTKESVALLAKAKEAGATVLTLVGHA
HCCCEEECCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCC
ETPLGKGADHAFVNFAEDDTSCESFYLQSLFIALSIMRHRGEIENYEQIAAELETLPQLL
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LEVKRAYEDKAEAFARVLAGSDYHIITGAGNVWPEAFYYGMCILEEMQWIRTRPVHASDF
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
FHGTLELVEKGVSVILFKGEDALRPLGDRVQNFAPNYTDRLTVLDTADFALPGVSDEVRG
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHH
LVSPIVLASVLERISAHLEVMRDHPLTTRRYYKRVAY
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLNFDEQRFLRIQSGAVALRKRLDDVIISCLEKGAENIFFLGTGGAAILMQPAAQLLQRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
SRFPAFIDMPAELFLTGSANLTEKSIVVIPSLSGTTKESVALLAKAKEAGATVLTLVGHA
HCCCEEECCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCC
ETPLGKGADHAFVNFAEDDTSCESFYLQSLFIALSIMRHRGEIENYEQIAAELETLPQLL
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LEVKRAYEDKAEAFARVLAGSDYHIITGAGNVWPEAFYYGMCILEEMQWIRTRPVHASDF
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
FHGTLELVEKGVSVILFKGEDALRPLGDRVQNFAPNYTDRLTVLDTADFALPGVSDEVRG
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHH
LVSPIVLASVLERISAHLEVMRDHPLTTRRYYKRVAY
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]