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The map label for this gene is lrp [H]

Identifier: 150398033

GI number: 150398033

Start: 2960158

End: 2960676

Strand: Reverse

Name: lrp [H]

Synonym: Smed_2835

Alternate gene names: 150398033

Gene position: 2960676-2960158 (Counterclockwise)

Preceding gene: 150398035

Following gene: 150398031

Centisome position: 78.29

GC content: 61.08

Gene sequence:

>519_bases
ATGGAGCAACTTGACGGATTCGACCTCAAGATTCTGAGCGAGCTTCAGCGCGATGGTCATCTGACCAACAACGAGTTGTC
CGAACGCGTCGCGCTCTCTCCTTCGCAGTGCTCGCGCCGCCGGACGCGTCTGGAGGCGGAAGGCATCATTACCGGCTATC
AGGCGCAGATCGACCGACAGAGACTGGGACTCGACCTGATGGTGGTGATTTCGGTCACGCTGGCCACGCACAACCGCGAC
AATGCCAAGCGCTTCGCCAATCTCGTCTCGGCCCTGCCGGAGGTGCTGGAGGCCTATGCGCTGACCGGTGAAATGGATTA
CCACCTGCGTGTCGTGACACCGGATCTTGCCGGACTCTCCCGCTTCGTCAACGAGGTGCTCCTTCCGCATGACAGCGTGC
AGCACGTCAAGACATCGATCGTGCTTGAGACGCTCAAGAGTTTCGAGGGGCTGCCGATACCGACGCAGATGAAGGGTGCC
GCCGCCATGCGCGTCGCTGCGAAACCTAGTCCGGCGTGA

Upstream 100 bases:

>100_bases
CTGGATTATGACGCAATTCCGATGCATGTTGCTTGTATTCTTGCGCGATTCAGCGGAATCTCTGCATGAAATGTGCGTAA
CGTCGTTTGCGGGTGCACGA

Downstream 100 bases:

>100_bases
CCGGCTTCTTCATCGCCTGCTCAATCGCCCGCAGACCCTTCAAGAGCGCCTCCATGTCCCGCGTGCCGATCATCGACAGC
AGTTCTGCCTGATAACCACG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MEQLDGFDLKILSELQRDGHLTNNELSERVALSPSQCSRRRTRLEAEGIITGYQAQIDRQRLGLDLMVVISVTLATHNRD
NAKRFANLVSALPEVLEAYALTGEMDYHLRVVTPDLAGLSRFVNEVLLPHDSVQHVKTSIVLETLKSFEGLPIPTQMKGA
AAMRVAAKPSPA

Sequences:

>Translated_172_residues
MEQLDGFDLKILSELQRDGHLTNNELSERVALSPSQCSRRRTRLEAEGIITGYQAQIDRQRLGLDLMVVISVTLATHNRD
NAKRFANLVSALPEVLEAYALTGEMDYHLRVVTPDLAGLSRFVNEVLLPHDSVQHVKTSIVLETLKSFEGLPIPTQMKGA
AAMRVAAKPSPA
>Mature_172_residues
MEQLDGFDLKILSELQRDGHLTNNELSERVALSPSQCSRRRTRLEAEGIITGYQAQIDRQRLGLDLMVVISVTLATHNRD
NAKRFANLVSALPEVLEAYALTGEMDYHLRVVTPDLAGLSRFVNEVLLPHDSVQHVKTSIVLETLKSFEGLPIPTQMKGA
AAMRVAAKPSPA

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=155, Percent_Identity=36.7741935483871, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=32.6666666666667, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 19015; Mature: 19015

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLDGFDLKILSELQRDGHLTNNELSERVALSPSQCSRRRTRLEAEGIITGYQAQIDRQ
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCEECHHHHHHHH
RLGLDLMVVISVTLATHNRDNAKRFANLVSALPEVLEAYALTGEMDYHLRVVTPDLAGLS
HHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
RFVNEVLLPHDSVQHVKTSIVLETLKSFEGLPIPTQMKGAAAMRVAAKPSPA
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCCCC
>Mature Secondary Structure
MEQLDGFDLKILSELQRDGHLTNNELSERVALSPSQCSRRRTRLEAEGIITGYQAQIDRQ
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCEECHHHHHHHH
RLGLDLMVVISVTLATHNRDNAKRFANLVSALPEVLEAYALTGEMDYHLRVVTPDLAGLS
HHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
RFVNEVLLPHDSVQHVKTSIVLETLKSFEGLPIPTQMKGAAAMRVAAKPSPA
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]