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The map label for this gene is 150397973

Identifier: 150397973

GI number: 150397973

Start: 2894719

End: 2895732

Strand: Direct

Name: 150397973

Synonym: Smed_2775

Alternate gene names: NA

Gene position: 2894719-2895732 (Clockwise)

Preceding gene: 150397972

Following gene: 150397978

Centisome position: 76.54

GC content: 64.1

Gene sequence:

>1014_bases
ATGCTGATTGCCCGCAGTGCCGGCCGCCTGCTAGCGACTGCGCTCCTGTTGACGGCCCTTTCCGCAACCTTCGCCGCCGC
CCAGTCGCCGCTCGGCATAGGCACTGCCGAGCCCTCAATCCGGACGACGGGCTTCCTCGGCGGTTTCTTTGCCTGGGTGA
ACATGGAGCAGCAGGGCTTCTACCGGATGCTGACCGACTCGCTCAAGGGCATGCGTGAGAACCCGTGGCAACTCTGGTCC
TTGATCGGCCTTTCCTTTGCCTATGGCGTCTTTCATGCGGCGGGACCCGGCCACGGTAAGGCCGTCATTTCGTCCTATAT
GATCGCCAATGAAACCGAGTTGAAGAGGGGCGTGCTCCTCTCGTTTCTCTCCTCGATCCTACAGGGCGTGGTCGCCATCC
TTCTGATCGGCGCCGTCTATCTCGTGCTGCGCGGTTCGTCCATCAGCATGACGAACGCCACGCGTGCGCTCGAAATCGCA
AGCTATGCGCTGATCGCAGCCTTTGGCGGCTGGCTGGTCTTCCGCAAGCTGCGGTCGATGCTGCGTCCGGCCCCCGCCCC
GGCCGCCGTTCATCCCCGTGATGATCATGATCATCATCATCATCACGACCACCACCACGCGCATGGTCCGGGCGAGGTCT
GCTCCTCCTGCGGCCACGCCCATGCGCCCGATCCGGCGCTTCTGAAGGGCGACCGTTTTGCGCTCACCGAAGCCTGGTCC
GCGATCGTCGCGGTCGGCATGCGCCCCTGCTCAGGGGCGCTGATCGTGCTTTCCTTCGCGCTCCTGAACGGGCTCTATCT
CGGCGGCGTCCTTTCGGTCTTCGCGATGTCGATCGGCACGGCGATCACCGTGTCGATCCTAGCGACCATGGCCGTCACCG
CGAAGGGCTTCGCCCTGCGCTACGCCTCGAACGATTCGGCTGCGGCACGGATTTCGAACGGAATCGAGATCGCCGGTGCC
TTGCTCGTCATGTTACTCGGGCTGGTGCTCCTGGCCGCGGCGCTGCAAAGCTGA

Upstream 100 bases:

>100_bases
AGGTGCTGGCGGAAAACAAGGATACGTTGACCGACGCCTTCTGGAGCGACCCGACCGGCACGGACATGTCGAAGCTCTTT
GCAACCAGGATCGAGATTAC

Downstream 100 bases:

>100_bases
AGCACCATCTCCCTGCCAGCAAACGGGAGAGGGCTGGTCCGGTCCTCGGCTTGCCACCCGAGGAGAGGGCAAATCGCGCG
CCAGCGCATGAGCGTGCGTC

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLIARSAGRLLATALLLTALSATFAAAQSPLGIGTAEPSIRTTGFLGGFFAWVNMEQQGFYRMLTDSLKGMRENPWQLWS
LIGLSFAYGVFHAAGPGHGKAVISSYMIANETELKRGVLLSFLSSILQGVVAILLIGAVYLVLRGSSISMTNATRALEIA
SYALIAAFGGWLVFRKLRSMLRPAPAPAAVHPRDDHDHHHHHDHHHAHGPGEVCSSCGHAHAPDPALLKGDRFALTEAWS
AIVAVGMRPCSGALIVLSFALLNGLYLGGVLSVFAMSIGTAITVSILATMAVTAKGFALRYASNDSAAARISNGIEIAGA
LLVMLLGLVLLAAALQS

Sequences:

>Translated_337_residues
MLIARSAGRLLATALLLTALSATFAAAQSPLGIGTAEPSIRTTGFLGGFFAWVNMEQQGFYRMLTDSLKGMRENPWQLWS
LIGLSFAYGVFHAAGPGHGKAVISSYMIANETELKRGVLLSFLSSILQGVVAILLIGAVYLVLRGSSISMTNATRALEIA
SYALIAAFGGWLVFRKLRSMLRPAPAPAAVHPRDDHDHHHHHDHHHAHGPGEVCSSCGHAHAPDPALLKGDRFALTEAWS
AIVAVGMRPCSGALIVLSFALLNGLYLGGVLSVFAMSIGTAITVSILATMAVTAKGFALRYASNDSAAARISNGIEIAGA
LLVMLLGLVLLAAALQS
>Mature_337_residues
MLIARSAGRLLATALLLTALSATFAAAQSPLGIGTAEPSIRTTGFLGGFFAWVNMEQQGFYRMLTDSLKGMRENPWQLWS
LIGLSFAYGVFHAAGPGHGKAVISSYMIANETELKRGVLLSFLSSILQGVVAILLIGAVYLVLRGSSISMTNATRALEIA
SYALIAAFGGWLVFRKLRSMLRPAPAPAAVHPRDDHDHHHHHDHHHAHGPGEVCSSCGHAHAPDPALLKGDRFALTEAWS
AIVAVGMRPCSGALIVLSFALLNGLYLGGVLSVFAMSIGTAITVSILATMAVTAKGFALRYASNDSAAARISNGIEIAGA
LLVMLLGLVLLAAALQS

Specific function: Efflux system for nickel and cobalt (Potential) [H]

COG id: COG2215

COG function: function code R; ABC-type uncharacterized transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 35415; Mature: 35415

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIARSAGRLLATALLLTALSATFAAAQSPLGIGTAEPSIRTTGFLGGFFAWVNMEQQGF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
YRMLTDSLKGMRENPWQLWSLIGLSFAYGVFHAAGPGHGKAVISSYMIANETELKRGVLL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHH
SFLSSILQGVVAILLIGAVYLVLRGSSISMTNATRALEIASYALIAAFGGWLVFRKLRSM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPAPAPAAVHPRDDHDHHHHHDHHHAHGPGEVCSSCGHAHAPDPALLKGDRFALTEAWS
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
AIVAVGMRPCSGALIVLSFALLNGLYLGGVLSVFAMSIGTAITVSILATMAVTAKGFALR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
YASNDSAAARISNGIEIAGALLVMLLGLVLLAAALQS
ECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIARSAGRLLATALLLTALSATFAAAQSPLGIGTAEPSIRTTGFLGGFFAWVNMEQQGF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
YRMLTDSLKGMRENPWQLWSLIGLSFAYGVFHAAGPGHGKAVISSYMIANETELKRGVLL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHH
SFLSSILQGVVAILLIGAVYLVLRGSSISMTNATRALEIASYALIAAFGGWLVFRKLRSM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPAPAPAAVHPRDDHDHHHHHDHHHAHGPGEVCSSCGHAHAPDPALLKGDRFALTEAWS
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
AIVAVGMRPCSGALIVLSFALLNGLYLGGVLSVFAMSIGTAITVSILATMAVTAKGFALR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
YASNDSAAARISNGIEIAGALLVMLLGLVLLAAALQS
ECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]