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The map label for this gene is ltaE [H]

Identifier: 150397910

GI number: 150397910

Start: 2826338

End: 2827384

Strand: Direct

Name: ltaE [H]

Synonym: Smed_2712

Alternate gene names: 150397910

Gene position: 2826338-2827384 (Clockwise)

Preceding gene: 150397907

Following gene: 150397912

Centisome position: 74.73

GC content: 64.37

Gene sequence:

>1047_bases
ATGATCTTCTCCTCCGACAACTGGGCCGGCGCCCATCCGGCGATTGCCGAGAGTCTGGTGACGCATGCGGCAGGCTATGC
GTCCGCCTATGGCACGAGCGAACTCGACCGGACGGTCGAGAAGAAATTTTCGGAGATTTTCGAAAAGGACGTTGCGGTAT
TTTTCGTCGGCACCGGAACTGCCGCGAACGCTCTTGCGCTTTCGAGCGCCAATCGGGCGGGCGGCATCGCTTTTTGCCAC
CGCGAGGCGCATGTAAACGTCGATGAGTGCGGCGCGCCGTCATTCTTCTCGCATGGTGCAAGACTCTGCCCGGTCGGGGG
CGAGCGCGGCAGAATGGATCCGGCGAAACTCGAGGCCGGGATCCGCCGGTTCCCGAAGGAGAACGTCCATGGCGGGCAGC
CGATGGCGGTGACTCTCACGCAGGCAACCGAGAGCGGCACCGTCTATCCGCTCGACCAGATCGAGTCGATCGGCTCCGTC
GCCACAGCCCACGAACTGCCGCTGCACATGGATGGCGCTCGCTTCGCCAACGCCCTGGTCAGCCTCGGAACGACACCCGC
CGAGATGACCTGGAAACGCGGCGTCGACCTCCTCTCCTTCGGAGGCACCAAAAACGGTTGCTGGTGCGCCGAAGCGCTGG
TCCTCTTCGATCGGTCCAGGGCGCAGCAGATGCATTTCCTGCGCAAGCGATCGGCCCAGCTTTTCTCCAAATCGCGCTTC
GTGGCCGCCCAGTTCGACGCATATCTCACCGGAGATCTCTGGCTCGATCTCGCCCGTCAAGCCAACGCAATGGCGCGGCG
CCTCGCCGACGGCATCACTGCCTCGGCGGAGAGCCGGCTTGCCTGGACGCCGGATGCCAACGAGGTCTTCGTCGTGCTGA
AACGAGAGGCGGCGAGCCGGCTGCGGGAGCAGGGCGCCCTTTTTTACGATTGGGACGTGCCGCACGATCTCGAGGGCAGC
CTGGCGGACAATGAAGGGCTCTATCGCCTCGTCACCAGCTTTGCGACGCGCGCCGAGGATGTCGACCGCTTCGTCGCCGC
CTGCTGA

Upstream 100 bases:

>100_bases
GACAGGGCGCAGCCGCTTGCTTGCCGTCGGGACTCGGCTATGGTCGCGCCGACGCACTTGTCGCGCCCGCGTGGCTGGAT
ACAAACAGGATAACTTCACG

Downstream 100 bases:

>100_bases
TCAGAGGTTATCCATATAAAGCAGGAAAGGCTCTAGAGCGCACGAACCTTCGAAAGGATCTCGCTGGAGAGTGCGGCGAT
CAGTTTGCGGTCGGCGCCCT

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MIFSSDNWAGAHPAIAESLVTHAAGYASAYGTSELDRTVEKKFSEIFEKDVAVFFVGTGTAANALALSSANRAGGIAFCH
REAHVNVDECGAPSFFSHGARLCPVGGERGRMDPAKLEAGIRRFPKENVHGGQPMAVTLTQATESGTVYPLDQIESIGSV
ATAHELPLHMDGARFANALVSLGTTPAEMTWKRGVDLLSFGGTKNGCWCAEALVLFDRSRAQQMHFLRKRSAQLFSKSRF
VAAQFDAYLTGDLWLDLARQANAMARRLADGITASAESRLAWTPDANEVFVVLKREAASRLREQGALFYDWDVPHDLEGS
LADNEGLYRLVTSFATRAEDVDRFVAAC

Sequences:

>Translated_348_residues
MIFSSDNWAGAHPAIAESLVTHAAGYASAYGTSELDRTVEKKFSEIFEKDVAVFFVGTGTAANALALSSANRAGGIAFCH
REAHVNVDECGAPSFFSHGARLCPVGGERGRMDPAKLEAGIRRFPKENVHGGQPMAVTLTQATESGTVYPLDQIESIGSV
ATAHELPLHMDGARFANALVSLGTTPAEMTWKRGVDLLSFGGTKNGCWCAEALVLFDRSRAQQMHFLRKRSAQLFSKSRF
VAAQFDAYLTGDLWLDLARQANAMARRLADGITASAESRLAWTPDANEVFVVLKREAASRLREQGALFYDWDVPHDLEGS
LADNEGLYRLVTSFATRAEDVDRFVAAC
>Mature_348_residues
MIFSSDNWAGAHPAIAESLVTHAAGYASAYGTSELDRTVEKKFSEIFEKDVAVFFVGTGTAANALALSSANRAGGIAFCH
REAHVNVDECGAPSFFSHGARLCPVGGERGRMDPAKLEAGIRRFPKENVHGGQPMAVTLTQATESGTVYPLDQIESIGSV
ATAHELPLHMDGARFANALVSLGTTPAEMTWKRGVDLLSFGGTKNGCWCAEALVLFDRSRAQQMHFLRKRSAQLFSKSRF
VAAQFDAYLTGDLWLDLARQANAMARRLADGITASAESRLAWTPDANEVFVVLKREAASRLREQGALFYDWDVPHDLEGS
LADNEGLYRLVTSFATRAEDVDRFVAAC

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37727; Mature: 37727

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSSDNWAGAHPAIAESLVTHAAGYASAYGTSELDRTVEKKFSEIFEKDVAVFFVGTGT
CEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEECCC
AANALALSSANRAGGIAFCHREAHVNVDECGAPSFFSHGARLCPVGGERGRMDPAKLEAG
CHHHHEECCCCCCCCEEEEECCCCCCHHHCCCCHHHHCCCEECCCCCCCCCCCHHHHHHH
IRRFPKENVHGGQPMAVTLTQATESGTVYPLDQIESIGSVATAHELPLHMDGARFANALV
HHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
SLGTTPAEMTWKRGVDLLSFGGTKNGCWCAEALVLFDRSRAQQMHFLRKRSAQLFSKSRF
HCCCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VAAQFDAYLTGDLWLDLARQANAMARRLADGITASAESRLAWTPDANEVFVVLKREAASR
EEEECCCEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEEEHHHHHH
LREQGALFYDWDVPHDLEGSLADNEGLYRLVTSFATRAEDVDRFVAAC
HHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFSSDNWAGAHPAIAESLVTHAAGYASAYGTSELDRTVEKKFSEIFEKDVAVFFVGTGT
CEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEECCC
AANALALSSANRAGGIAFCHREAHVNVDECGAPSFFSHGARLCPVGGERGRMDPAKLEAG
CHHHHEECCCCCCCCEEEEECCCCCCHHHCCCCHHHHCCCEECCCCCCCCCCCHHHHHHH
IRRFPKENVHGGQPMAVTLTQATESGTVYPLDQIESIGSVATAHELPLHMDGARFANALV
HHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
SLGTTPAEMTWKRGVDLLSFGGTKNGCWCAEALVLFDRSRAQQMHFLRKRSAQLFSKSRF
HCCCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VAAQFDAYLTGDLWLDLARQANAMARRLADGITASAESRLAWTPDANEVFVVLKREAASR
EEEECCCEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEEEHHHHHH
LREQGALFYDWDVPHDLEGSLADNEGLYRLVTSFATRAEDVDRFVAAC
HHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]