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The map label for this gene is pabB [H]

Identifier: 150397883

GI number: 150397883

Start: 2788831

End: 2789988

Strand: Direct

Name: pabB [H]

Synonym: Smed_2685

Alternate gene names: 150397883

Gene position: 2788831-2789988 (Clockwise)

Preceding gene: 150397882

Following gene: 150397884

Centisome position: 73.74

GC content: 64.34

Gene sequence:

>1158_bases
ATGATCGAACACGCGCCCTATGTCCTCTTCCGGGACGACAGCGAGAACCGCACCACGGTTTTCGCCGACCCTTTGCGCGT
CGTCACGGCCCGGACGAGGGCTGAGTTTCACCGCGGCCTTGGTGAAATCGAAGCGGCCCATCGTGCGGGAAAATGGATCG
CGGGCTTCATGGCCTATGAAGCGGGGCATCTTTTCGAGACGAAGCTGGCCCCCTTCGCGCCGGAGAACCGGGAAACGCCG
CTGATGTCATTCGGGGTCTTCGACGCGCCGGCGGAGGACCATGCGCTTGCCGTGGCGCGGCGGCGCAGCGAAAACGAACC
CTTCCTCCTGGAGCCTCGCGCCGGCTGGGATTTTCCTGCTTATCGCCAGCGCTTCGAAAGGCTGCACCGGCATCTGCGCC
AGGGCGATTGCTACCAGGCGAACCTGACCATGCCGATCCAAGCGCGCTGGTCCGGCGATCCGCTTGCCGCCTTCTGGTCG
CTCATCGAGCGTCAGCCGGTGAGATACGGCGCACTCGTCGCCCTCGACGGCCCAGTGCTGCTGTCGCGCTCACCCGAGCT
TTTCTTCCGGGTCGATGCCGAGGGCTGGATCGAAACGCACCCGATGAAGGGCACGGCGCGGCGCGGCGCGAGCCCTAAGG
AAGATGATGCGATCATCGCGGCGATGCGCGCCGACGAGAAGACGCAAGCCGAAAACCGCATGATCGTCGACCTTCTGCGC
AACGACATCTCCCGCGTCACCGAAGTCGGCACGCTCGACGTGCCTAAACTCTTCGATATCGAGACCTATCCGACGGTCCA
TCAGATGGTGAGCCATGTCAGGGCGAAGCTTCTGACGGACATCGGCATCGCCGACATCTTCGCCGCACTCTTTCCCTGCG
GCTCCGTTACCGGCGCGCCGAAGATGCGGGCCATGGAAATTCTTCACGACCTGGAGTCCGGCCCGCGCGACGCCTATTGT
GGCGCGATCGGCTACATCGCGCCGGACGGGGCGATGCGCTTCAGCGTCGCGATCCGCACCATTTCCCTTTTCCCCGGGGG
GGAGGCGGTGTTCAATGTCGGCGGTGGCATCGTCTTCGATTCGACGGCCGAGGCGGAATACGAAGAATGCCTGCTGAAGG
CCCGTTTCGCCGTCGGCGATGCGGAGATCGCTCGATGA

Upstream 100 bases:

>100_bases
ATGATTGAGGGGCTCATCGACGAACTGGAGGCGCTTGATAAGGCGTAACCCGCTCGGGCAATCAGCCCCGTCGGACCGAG
TTTGACAGCGACCGACCTCA

Downstream 100 bases:

>100_bases
TCGGTTTTTCCCTGATCGAGACGCTGCGCTACGAACCGGAGCATGGCTTTGCGCGGCTGCCGCTGCATCTGGCGCGGTTG
ACGCGCTCCGCCAGGCGCCT

Product: aminodeoxychorismate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MIEHAPYVLFRDDSENRTTVFADPLRVVTARTRAEFHRGLGEIEAAHRAGKWIAGFMAYEAGHLFETKLAPFAPENRETP
LMSFGVFDAPAEDHALAVARRRSENEPFLLEPRAGWDFPAYRQRFERLHRHLRQGDCYQANLTMPIQARWSGDPLAAFWS
LIERQPVRYGALVALDGPVLLSRSPELFFRVDAEGWIETHPMKGTARRGASPKEDDAIIAAMRADEKTQAENRMIVDLLR
NDISRVTEVGTLDVPKLFDIETYPTVHQMVSHVRAKLLTDIGIADIFAALFPCGSVTGAPKMRAMEILHDLESGPRDAYC
GAIGYIAPDGAMRFSVAIRTISLFPGGEAVFNVGGGIVFDSTAEAEYEECLLKARFAVGDAEIAR

Sequences:

>Translated_385_residues
MIEHAPYVLFRDDSENRTTVFADPLRVVTARTRAEFHRGLGEIEAAHRAGKWIAGFMAYEAGHLFETKLAPFAPENRETP
LMSFGVFDAPAEDHALAVARRRSENEPFLLEPRAGWDFPAYRQRFERLHRHLRQGDCYQANLTMPIQARWSGDPLAAFWS
LIERQPVRYGALVALDGPVLLSRSPELFFRVDAEGWIETHPMKGTARRGASPKEDDAIIAAMRADEKTQAENRMIVDLLR
NDISRVTEVGTLDVPKLFDIETYPTVHQMVSHVRAKLLTDIGIADIFAALFPCGSVTGAPKMRAMEILHDLESGPRDAYC
GAIGYIAPDGAMRFSVAIRTISLFPGGEAVFNVGGGIVFDSTAEAEYEECLLKARFAVGDAEIAR
>Mature_385_residues
MIEHAPYVLFRDDSENRTTVFADPLRVVTARTRAEFHRGLGEIEAAHRAGKWIAGFMAYEAGHLFETKLAPFAPENRETP
LMSFGVFDAPAEDHALAVARRRSENEPFLLEPRAGWDFPAYRQRFERLHRHLRQGDCYQANLTMPIQARWSGDPLAAFWS
LIERQPVRYGALVALDGPVLLSRSPELFFRVDAEGWIETHPMKGTARRGASPKEDDAIIAAMRADEKTQAENRMIVDLLR
NDISRVTEVGTLDVPKLFDIETYPTVHQMVSHVRAKLLTDIGIADIFAALFPCGSVTGAPKMRAMEILHDLESGPRDAYC
GAIGYIAPDGAMRFSVAIRTISLFPGGEAVFNVGGGIVFDSTAEAEYEECLLKARFAVGDAEIAR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=387, Percent_Identity=36.6925064599483, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787518, Length=259, Percent_Identity=31.6602316602317, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786809, Length=215, Percent_Identity=28.3720930232558, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=255, Percent_Identity=35.6862745098039, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324361, Length=279, Percent_Identity=31.1827956989247, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 42847; Mature: 42847

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEHAPYVLFRDDSENRTTVFADPLRVVTARTRAEFHRGLGEIEAAHRAGKWIAGFMAYE
CCCCCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AGHLFETKLAPFAPENRETPLMSFGVFDAPAEDHALAVARRRSENEPFLLEPRAGWDFPA
CCCCEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCHH
YRQRFERLHRHLRQGDCYQANLTMPIQARWSGDPLAAFWSLIERQPVRYGALVALDGPVL
HHHHHHHHHHHHHCCCCEEECEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCEE
LSRSPELFFRVDAEGWIETHPMKGTARRGASPKEDDAIIAAMRADEKTQAENRMIVDLLR
ECCCCCEEEEECCCCCEEECCCCCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
NDISRVTEVGTLDVPKLFDIETYPTVHQMVSHVRAKLLTDIGIADIFAALFPCGSVTGAP
HHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
KMRAMEILHDLESGPRDAYCGAIGYIAPDGAMRFSVAIRTISLFPGGEAVFNVGGGIVFD
HHHHHHHHHHHHCCCCCCCCCEECEECCCCCEEEEEEEEEEEECCCCCEEEECCCCEEEC
STAEAEYEECLLKARFAVGDAEIAR
CCCHHHHHHHHHHHHHHCCCHHHCC
>Mature Secondary Structure
MIEHAPYVLFRDDSENRTTVFADPLRVVTARTRAEFHRGLGEIEAAHRAGKWIAGFMAYE
CCCCCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AGHLFETKLAPFAPENRETPLMSFGVFDAPAEDHALAVARRRSENEPFLLEPRAGWDFPA
CCCCEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCHH
YRQRFERLHRHLRQGDCYQANLTMPIQARWSGDPLAAFWSLIERQPVRYGALVALDGPVL
HHHHHHHHHHHHHCCCCEEECEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCEE
LSRSPELFFRVDAEGWIETHPMKGTARRGASPKEDDAIIAAMRADEKTQAENRMIVDLLR
ECCCCCEEEEECCCCCEEECCCCCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
NDISRVTEVGTLDVPKLFDIETYPTVHQMVSHVRAKLLTDIGIADIFAALFPCGSVTGAP
HHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
KMRAMEILHDLESGPRDAYCGAIGYIAPDGAMRFSVAIRTISLFPGGEAVFNVGGGIVFD
HHHHHHHHHHHHCCCCCCCCCEECEECCCCCEEEEEEEEEEEECCCCCEEEECCCCEEEC
STAEAEYEECLLKARFAVGDAEIAR
CCCHHHHHHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]