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The map label for this gene is cbbT [H]

Identifier: 150397848

GI number: 150397848

Start: 2753171

End: 2755126

Strand: Direct

Name: cbbT [H]

Synonym: Smed_2650

Alternate gene names: 150397848

Gene position: 2753171-2755126 (Clockwise)

Preceding gene: 150397845

Following gene: 150397849

Centisome position: 72.8

GC content: 63.24

Gene sequence:

>1956_bases
ATGGCGAATGCAATCCGTTTCCTCTCCATGGACGCCGTCGAGAAGGCAAATTCCGGCCACCCTGGCCTCCCAATGGGCGC
CGCCGATATCGCCACGGTGCTGTTTACCCGCTATCTGAGCTTCGATCCGAAAAACCCCGCCTGGCCGAACCGTGACCGTT
TCGTGCTTTCGGCCGGCCACGGATCCATGCTGCTCTATTCGCTGCTCTATCTCACGGGCTACGACGACATCACCATCGAC
GAGATCAAGAATTTCCGCCAGCTGGGTTCGCGCACGGCAGGCCACCCGGAATACGGACACGCCGCGGGCATCGAGACGAC
GACCGGTCCGCTCGGCCAGGGCATTGCCAACTCCGTCGGCATGGCGATCGCCGAGCGCAAGCTGCGCGAGGAGTTCGGCA
GCGAGCTGATGGAGCATTATACCTATGTGCTTGCCGGCGACGGCTGCCTGATGGAAGGCGTGAGCCAGGAAGCCATCGCG
CTTGCCGGTCATCTGAAGCTAAACAAGCTGATCGTCTTTTGGGACGACAACAATATTTCCATCGACGGCCCGATCTCGCT
TGCCGATTCGACCGACCAGCACGCGCGCTTCCGCGCCTGCAAGTGGCACACCATCGCCGTGAACGGCCATGACCCCGAAG
CGATCGCCGCCGCGATCGAGGAGGCCCAGAAGTCCGACAAGCCGACCATGATCGCCTGCAAAACCGTGATCGGCTTCGGC
GCGCCGAACAAGGCCGGTACCCACAAGGTCCACGGCTCACCGCTCGGCGCCGAGGAAATCGCAGCCACCCGCAAGGCGCT
CGGCTGGGAGGCCGAAGCTTTCACGGTCCCCTCGGACGTGCTTGATGCCTGGCGTATCGCGGGCCTGCGTTCGGCCAAGG
CACGCAAGGAATGGGAAGAGCGGCTCGAAGCCGCCGAGGCGGAGAAGAAAGCCCATTTCATCCGCCGCTTCTCCGGCGAA
CTCGAAGGCAGCCTCGCCTCGGCGATCAGCGCCTACAAGCAGAAGCTTGCCGAGACCAAGCCTTCGCCGGCGACCCGCAA
GGCCTCGGAGGATGCGCTGGAGGTGATCAACGGCGTGCTTGCAGAGACGATCGGCGGCTCGGCCGACCTGACCGGCTCCA
ACAACACCAAGACGAGCCAGACCCACTCCATCACCCCGGACGATTTCTCCGGACGCTACATTCACTACGGCGTGCGCGAG
CATGGCATGGCGGCCGCGATGAACGGTATGGCGCTGCATGGTGGTCTCATTCCCTATTCCGGCGGCTTCCTGATCTTCTC
GGATTACTGCCGCCCATCCATCCGCCTGGCCGCCCTCATGGGTATCCGCGTCATCCACGTGCTGACACACGATTCCATCG
GCCTCGGCGAAGACGGACCGACCCACCAGCCGGTCGAGCATATGGCTGCTCTTCGGGCCATCCCTAACCTCCTGATGTTC
CGCCCCGCGGATGCGACCGAGACCGCCGAATGCTGGCAGCTTGCGCTGGAGAACCGCAAACGTCCCTCGGGTCTTGCGCT
TACCCGCCAGAACCTCATGGCGGTGCGCACCGAATACGAGGAACAGAACCTCTGCGCCCGCGGCGCCTATGACCTGATTT
CGGCAAGCGACGCGCAGGTCACGATCTTCGCCACCGGCTCCGAAGTCGAGATCGCCGTGAAGGCCTGCCAGACGCTGACT
GCCAAGGGTATCGCGACACGCGTCGTCTCGGTTCCCTGCTTCGAGCTCTTTGCGGAGCAGAGCGAGGATTACCAGCAGGC
GATCATCGGCACGTCGCCGGTCAAGATCGCCGTCGAAGCCGGCATCCGCCAGGGCTGGGACCACTTCATCGGCAATGATG
GTATCTTCATCGGCATGTCGAGCTTCGGGGCTTCGGGCCCCTATAAGGACCTCTACAAACACTTCGGAATTACGCCGGAA
GTCGTGGTTGCGTCCGCCGAAGCCAAGCTGTCCTGA

Upstream 100 bases:

>100_bases
TGTCTGCCGCTTCTCATGCGGTCTTTGGAGGATAGAGACCGTCCCCTGACCACCGAACGCAAACGGAAAAGTCATGATCT
CTCGCGAAAAACACGACCGG

Downstream 100 bases:

>100_bases
TCAAGCCGGAGGGCGCCGCAAGAGCGTCCTCCTTCCCACCACACGCATTCTGACAGGGAGAGACCCGATATGAGAGTCAA
AGTCGCCATCAACGGTTTCG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MANAIRFLSMDAVEKANSGHPGLPMGAADIATVLFTRYLSFDPKNPAWPNRDRFVLSAGHGSMLLYSLLYLTGYDDITID
EIKNFRQLGSRTAGHPEYGHAAGIETTTGPLGQGIANSVGMAIAERKLREEFGSELMEHYTYVLAGDGCLMEGVSQEAIA
LAGHLKLNKLIVFWDDNNISIDGPISLADSTDQHARFRACKWHTIAVNGHDPEAIAAAIEEAQKSDKPTMIACKTVIGFG
APNKAGTHKVHGSPLGAEEIAATRKALGWEAEAFTVPSDVLDAWRIAGLRSAKARKEWEERLEAAEAEKKAHFIRRFSGE
LEGSLASAISAYKQKLAETKPSPATRKASEDALEVINGVLAETIGGSADLTGSNNTKTSQTHSITPDDFSGRYIHYGVRE
HGMAAAMNGMALHGGLIPYSGGFLIFSDYCRPSIRLAALMGIRVIHVLTHDSIGLGEDGPTHQPVEHMAALRAIPNLLMF
RPADATETAECWQLALENRKRPSGLALTRQNLMAVRTEYEEQNLCARGAYDLISASDAQVTIFATGSEVEIAVKACQTLT
AKGIATRVVSVPCFELFAEQSEDYQQAIIGTSPVKIAVEAGIRQGWDHFIGNDGIFIGMSSFGASGPYKDLYKHFGITPE
VVVASAEAKLS

Sequences:

>Translated_651_residues
MANAIRFLSMDAVEKANSGHPGLPMGAADIATVLFTRYLSFDPKNPAWPNRDRFVLSAGHGSMLLYSLLYLTGYDDITID
EIKNFRQLGSRTAGHPEYGHAAGIETTTGPLGQGIANSVGMAIAERKLREEFGSELMEHYTYVLAGDGCLMEGVSQEAIA
LAGHLKLNKLIVFWDDNNISIDGPISLADSTDQHARFRACKWHTIAVNGHDPEAIAAAIEEAQKSDKPTMIACKTVIGFG
APNKAGTHKVHGSPLGAEEIAATRKALGWEAEAFTVPSDVLDAWRIAGLRSAKARKEWEERLEAAEAEKKAHFIRRFSGE
LEGSLASAISAYKQKLAETKPSPATRKASEDALEVINGVLAETIGGSADLTGSNNTKTSQTHSITPDDFSGRYIHYGVRE
HGMAAAMNGMALHGGLIPYSGGFLIFSDYCRPSIRLAALMGIRVIHVLTHDSIGLGEDGPTHQPVEHMAALRAIPNLLMF
RPADATETAECWQLALENRKRPSGLALTRQNLMAVRTEYEEQNLCARGAYDLISASDAQVTIFATGSEVEIAVKACQTLT
AKGIATRVVSVPCFELFAEQSEDYQQAIIGTSPVKIAVEAGIRQGWDHFIGNDGIFIGMSSFGASGPYKDLYKHFGITPE
VVVASAEAKLS
>Mature_650_residues
ANAIRFLSMDAVEKANSGHPGLPMGAADIATVLFTRYLSFDPKNPAWPNRDRFVLSAGHGSMLLYSLLYLTGYDDITIDE
IKNFRQLGSRTAGHPEYGHAAGIETTTGPLGQGIANSVGMAIAERKLREEFGSELMEHYTYVLAGDGCLMEGVSQEAIAL
AGHLKLNKLIVFWDDNNISIDGPISLADSTDQHARFRACKWHTIAVNGHDPEAIAAAIEEAQKSDKPTMIACKTVIGFGA
PNKAGTHKVHGSPLGAEEIAATRKALGWEAEAFTVPSDVLDAWRIAGLRSAKARKEWEERLEAAEAEKKAHFIRRFSGEL
EGSLASAISAYKQKLAETKPSPATRKASEDALEVINGVLAETIGGSADLTGSNNTKTSQTHSITPDDFSGRYIHYGVREH
GMAAAMNGMALHGGLIPYSGGFLIFSDYCRPSIRLAALMGIRVIHVLTHDSIGLGEDGPTHQPVEHMAALRAIPNLLMFR
PADATETAECWQLALENRKRPSGLALTRQNLMAVRTEYEEQNLCARGAYDLISASDAQVTIFATGSEVEIAVKACQTLTA
KGIATRVVSVPCFELFAEQSEDYQQAIIGTSPVKIAVEAGIRQGWDHFIGNDGIFIGMSSFGASGPYKDLYKHFGITPEV
VVASAEAKLS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=576, Percent_Identity=27.4305555555556, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI4507521, Length=576, Percent_Identity=27.4305555555556, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI133778974, Length=573, Percent_Identity=26.7015706806283, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI225637459, Length=269, Percent_Identity=24.907063197026, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI225637461, Length=241, Percent_Identity=24.0663900414938, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI48994911, Length=661, Percent_Identity=50.3782148260212, Blast_Score=641, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=663, Percent_Identity=49.3212669683258, Blast_Score=620, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI17539652, Length=572, Percent_Identity=27.2727272727273, Blast_Score=156, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6325331, Length=668, Percent_Identity=43.7125748502994, Blast_Score=510, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6319593, Length=670, Percent_Identity=42.3880597014925, Blast_Score=479, Evalue=1e-136,
Organism=Drosophila melanogaster, GI45551847, Length=572, Percent_Identity=28.3216783216783, Blast_Score=169, Evalue=8e-42,
Organism=Drosophila melanogaster, GI45550715, Length=572, Percent_Identity=28.3216783216783, Blast_Score=169, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24645119, Length=541, Percent_Identity=28.0961182994455, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666278, Length=571, Percent_Identity=25.3940455341506, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 70157; Mature: 70026

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAIRFLSMDAVEKANSGHPGLPMGAADIATVLFTRYLSFDPKNPAWPNRDRFVLSAGH
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
GSMLLYSLLYLTGYDDITIDEIKNFRQLGSRTAGHPEYGHAAGIETTTGPLGQGIANSVG
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
MAIAERKLREEFGSELMEHYTYVLAGDGCLMEGVSQEAIALAGHLKLNKLIVFWDDNNIS
HHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCHHHHHHHCCEEEEEEEEEECCCCEE
IDGPISLADSTDQHARFRACKWHTIAVNGHDPEAIAAAIEEAQKSDKPTMIACKTVIGFG
ECCCEEECCCCCHHHHHEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEHHHCCC
APNKAGTHKVHGSPLGAEEIAATRKALGWEAEAFTVPSDVLDAWRIAGLRSAKARKEWEE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
RLEAAEAEKKAHFIRRFSGELEGSLASAISAYKQKLAETKPSPATRKASEDALEVINGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AETIGGSADLTGSNNTKTSQTHSITPDDFSGRYIHYGVREHGMAAAMNGMALHGGLIPYS
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHCCHHHHHCCEEEECCCCCCC
GGFLIFSDYCRPSIRLAALMGIRVIHVLTHDSIGLGEDGPTHQPVEHMAALRAIPNLLMF
CCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHEE
RPADATETAECWQLALENRKRPSGLALTRQNLMAVRTEYEEQNLCARGAYDLISASDAQV
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCHHHHCCCCCEE
TIFATGSEVEIAVKACQTLTAKGIATRVVSVPCFELFAEQSEDYQQAIIGTSPVKIAVEA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEH
GIRQGWDHFIGNDGIFIGMSSFGASGPYKDLYKHFGITPEVVVASAEAKLS
HHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCHHHEEECCCCCCC
>Mature Secondary Structure 
ANAIRFLSMDAVEKANSGHPGLPMGAADIATVLFTRYLSFDPKNPAWPNRDRFVLSAGH
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
GSMLLYSLLYLTGYDDITIDEIKNFRQLGSRTAGHPEYGHAAGIETTTGPLGQGIANSVG
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
MAIAERKLREEFGSELMEHYTYVLAGDGCLMEGVSQEAIALAGHLKLNKLIVFWDDNNIS
HHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCHHHHHHHCCEEEEEEEEEECCCCEE
IDGPISLADSTDQHARFRACKWHTIAVNGHDPEAIAAAIEEAQKSDKPTMIACKTVIGFG
ECCCEEECCCCCHHHHHEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEHHHCCC
APNKAGTHKVHGSPLGAEEIAATRKALGWEAEAFTVPSDVLDAWRIAGLRSAKARKEWEE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
RLEAAEAEKKAHFIRRFSGELEGSLASAISAYKQKLAETKPSPATRKASEDALEVINGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AETIGGSADLTGSNNTKTSQTHSITPDDFSGRYIHYGVREHGMAAAMNGMALHGGLIPYS
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHCCHHHHHCCEEEECCCCCCC
GGFLIFSDYCRPSIRLAALMGIRVIHVLTHDSIGLGEDGPTHQPVEHMAALRAIPNLLMF
CCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHEE
RPADATETAECWQLALENRKRPSGLALTRQNLMAVRTEYEEQNLCARGAYDLISASDAQV
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCHHHHCCCCCEE
TIFATGSEVEIAVKACQTLTAKGIATRVVSVPCFELFAEQSEDYQQAIIGTSPVKIAVEA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEH
GIRQGWDHFIGNDGIFIGMSSFGASGPYKDLYKHFGITPEVVVASAEAKLS
HHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]