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The map label for this gene is plsC [C]

Identifier: 150397744

GI number: 150397744

Start: 2644593

End: 2645372

Strand: Direct

Name: plsC [C]

Synonym: Smed_2546

Alternate gene names: 150397744

Gene position: 2644593-2645372 (Clockwise)

Preceding gene: 150397743

Following gene: 150397746

Centisome position: 69.93

GC content: 61.92

Gene sequence:

>780_bases
ATGATCATCCTGCGTTCGATCCTCTTCAACCTGGCCTTCTACGCCAACCTGGTCGTGCAGATGATCGTGCTGACGCCGAT
CTATTTCCTCGTGCCGCGCAAAACGGCCTGGTTCGTGCCCAAGAACTGGGCGCGAAGCAACCATTGGCTCCTAGCGAAGA
TCGTCGGAACGACCTTCGAGGTCGAAGGCCTCGATAACATTCCCAAAGGCGCCTACATCTTCGCGCCGAAGCATCAGTCC
TTCTGGGATGTCTATGCGCTTCTGCCCTGGCTCGACGATCCCTTCTTCATTCTCAAGCGGGAGCTCACCTGGATACCGCT
GTTCGGCTGGTACGTTATGAAGCAGCGCATGGTTCCGGTGAACCGCGCCGCGCGCGGCAAGGCGATGGCCGCGGTCATGG
AGCGCACGAAGCACGAGATGGCAACGGGTCGTCAGCTGATCATCTATCCTGAAGGAACGCGACGTCCGCCCGGCGCGCCG
CCGGAATACAAATATGGCATAGCCCGGCTCTACCGCGACCTCCAGGTTCCGGTGGTTCCCGTTGCAATGCATCCGGGGCT
GTTCTGGCCCCGCCGCAAGTTCCTGCGTTTCCCCGGCCACTTCAAGGTGCGGGTCCTTCCGCCGATCGAGGCCGGTCTGG
ATCCGGACGCCTTTCTCGCGAAGCTGGTGGAAGTGACGGAGGCGGCGAGCGACGACCTGCTCGTCGAAACGGTGAACGCC
AATCCGCATCTGCCGCTGCCGCCCACTGCCGAACAGCGGCTGCGCGAACTTGCAGCGTGA

Upstream 100 bases:

>100_bases
AGGATCGCTCCTCCAGTAATGCGCCGATACGGCTGTTTTCCTCGCGCGCATATTCGTGTAGGCAGCGTGGCGTCCATATC
CGCTTCGAGAGTCTGCCCTG

Downstream 100 bases:

>100_bases
TCGCGGGAGCGAGGCGGGCATCACCCGCCCGCGTGCAGGCTTCGGTCGGGCGGTGCTTCGCTAGCCGCCAACCTCGCGGC
AACCTCCTCCAGCCAGTGGT

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase Domain Protein; Acyltransferase Family Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Scaffold Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; 2-Acylglycerophosphoethanolamine Acyltransferase; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MIILRSILFNLAFYANLVVQMIVLTPIYFLVPRKTAWFVPKNWARSNHWLLAKIVGTTFEVEGLDNIPKGAYIFAPKHQS
FWDVYALLPWLDDPFFILKRELTWIPLFGWYVMKQRMVPVNRAARGKAMAAVMERTKHEMATGRQLIIYPEGTRRPPGAP
PEYKYGIARLYRDLQVPVVPVAMHPGLFWPRRKFLRFPGHFKVRVLPPIEAGLDPDAFLAKLVEVTEAASDDLLVETVNA
NPHLPLPPTAEQRLRELAA

Sequences:

>Translated_259_residues
MIILRSILFNLAFYANLVVQMIVLTPIYFLVPRKTAWFVPKNWARSNHWLLAKIVGTTFEVEGLDNIPKGAYIFAPKHQS
FWDVYALLPWLDDPFFILKRELTWIPLFGWYVMKQRMVPVNRAARGKAMAAVMERTKHEMATGRQLIIYPEGTRRPPGAP
PEYKYGIARLYRDLQVPVVPVAMHPGLFWPRRKFLRFPGHFKVRVLPPIEAGLDPDAFLAKLVEVTEAASDDLLVETVNA
NPHLPLPPTAEQRLRELAA
>Mature_259_residues
MIILRSILFNLAFYANLVVQMIVLTPIYFLVPRKTAWFVPKNWARSNHWLLAKIVGTTFEVEGLDNIPKGAYIFAPKHQS
FWDVYALLPWLDDPFFILKRELTWIPLFGWYVMKQRMVPVNRAARGKAMAAVMERTKHEMATGRQLIIYPEGTRRPPGAP
PEYKYGIARLYRDLQVPVVPVAMHPGLFWPRRKFLRFPGHFKVRVLPPIEAGLDPDAFLAKLVEVTEAASDDLLVETVNA
NPHLPLPPTAEQRLRELAA

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5453718, Length=167, Percent_Identity=30.5389221556886, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI15100175, Length=167, Percent_Identity=30.5389221556886, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364648, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24582856, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24582854, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 29765; Mature: 29765

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILRSILFNLAFYANLVVQMIVLTPIYFLVPRKTAWFVPKNWARSNHWLLAKIVGTTFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCCCEEEEEEECCEEE
VEGLDNIPKGAYIFAPKHQSFWDVYALLPWLDDPFFILKRELTWIPLFGWYVMKQRMVPV
ECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCEEEHHHHHHHHHHCCCC
NRAARGKAMAAVMERTKHEMATGRQLIIYPEGTRRPPGAPPEYKYGIARLYRDLQVPVVP
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
VAMHPGLFWPRRKFLRFPGHFKVRVLPPIEAGLDPDAFLAKLVEVTEAASDDLLVETVNA
EEECCCCCCCCHHHHCCCCCEEEEEECCHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
NPHLPLPPTAEQRLRELAA
CCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MIILRSILFNLAFYANLVVQMIVLTPIYFLVPRKTAWFVPKNWARSNHWLLAKIVGTTFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCCCEEEEEEECCEEE
VEGLDNIPKGAYIFAPKHQSFWDVYALLPWLDDPFFILKRELTWIPLFGWYVMKQRMVPV
ECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCEEEHHHHHHHHHHCCCC
NRAARGKAMAAVMERTKHEMATGRQLIIYPEGTRRPPGAPPEYKYGIARLYRDLQVPVVP
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
VAMHPGLFWPRRKFLRFPGHFKVRVLPPIEAGLDPDAFLAKLVEVTEAASDDLLVETVNA
EEECCCCCCCCHHHHCCCCCEEEEEECCHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
NPHLPLPPTAEQRLRELAA
CCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA