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The map label for this gene is hmuS [H]

Identifier: 150397538

GI number: 150397538

Start: 2415116

End: 2416183

Strand: Direct

Name: hmuS [H]

Synonym: Smed_2338

Alternate gene names: 150397538

Gene position: 2415116-2416183 (Clockwise)

Preceding gene: 150397537

Following gene: 150397539

Centisome position: 63.86

GC content: 62.17

Gene sequence:

>1068_bases
ATGACGATGACTGAGAGCATGCGCCCCACCCCTGCTGAAATCCGTGCCTATCGCGCTGAAAACCCCAAGCTTCGCGAGCG
CGACATTGCTGCGCAGCTCGGCATTTCGGAGGCAGCGCTGGTCGCTGCCGAATGCGGTCTCACCGCCATCCGAATCGAAT
CCAGCGCCAACCGCTTCCTTGAACGCGCCGAAGAACTGGGCGAGGTCCTTGCGCTGACCCGCAATGAAAGCGCCGTCCAC
GAAAAGGTCGGACTCTACGAGAACGTAAAGCAGGGGCACGCCGCGACGCTGGTACTTGGGTCCGAAATCGACCTGCGCGT
CTTCCCTGGCGCCTGGGAACACGGCTTCGCCGTTACAAAAACCGATGCCAAGGGGGAGGTTCGCCGCAGCCTGCAGTTTT
TCGACAAATGGGGCAACGCGGTGCACAAGGTCCACTTGCGCCCTGCATCGCATCTCGCGGCCTACGAGAAGCTTGTTGAA
GACCTTCGCCTTGACGACCAATCGCAAGACTTCATTGCCGATCCAGGCGCGCCTGCAAACGACGACGTGACCGATGACTC
GGTCGATACGGCAGAGCTGCGCGATCGCTGGTCGAAGCTCACCGACACGCATCAGTTCCCGGGCATGTTGAGAAAGCTCA
AGGTCGGTCGGCGCCGGGCGCTGCATTCGATCGGCGACGACTTCGCCTGGCGCCTCGACACCGCCAGCGTCGAAACGATG
ATGCGCAGTGCCGCAGAAACGGCGCTGCCGATCATGTGCTTCGTAGGCAATCGCGGGGTCATCCAGATCCACTCCGGTCC
GGTCGTGAAGATCGGGACGATGGGGCCGTGGCTGAACGTCATGGACGAAACTTTCCATCTGCATCTGCGCACCGACCACA
TCACCGAACTGTGGGCCGTGCGCAAGCCGACGGCGGACGGACATGTGACATCCGTCGAGGGGCTCGACGCCAAGGGCGAG
ATGATCATTCAGTTCTTCGGAAAGCGGAAGGAAGGGTCCTCGGAAAGGGCCGAATGGCGCAGCCTGGCCGAGGGACTGCC
GCGTCTGAAGACCGTCGTCGCGGCCTGA

Upstream 100 bases:

>100_bases
CTTTTCCGTGGCCAGAGCGAGATTCTTATTTCCCACGACGGAGCGATCTACCGGATGAAGATCACCCGCCAGGGCAAGCT
GATTCTGAACAAATAGCGAG

Downstream 100 bases:

>100_bases
TGGCTCCGCCCGTCGGTGGGCGGCTTCCCCATGACGATAGGTCCGCAATCGCGAGCGTGATTGGTTACAACGAGATAGGG
CGGGATGCGGGCGGAAACCG

Product: hemin-degrading family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTMTESMRPTPAEIRAYRAENPKLRERDIAAQLGISEAALVAAECGLTAIRIESSANRFLERAEELGEVLALTRNESAVH
EKVGLYENVKQGHAATLVLGSEIDLRVFPGAWEHGFAVTKTDAKGEVRRSLQFFDKWGNAVHKVHLRPASHLAAYEKLVE
DLRLDDQSQDFIADPGAPANDDVTDDSVDTAELRDRWSKLTDTHQFPGMLRKLKVGRRRALHSIGDDFAWRLDTASVETM
MRSAAETALPIMCFVGNRGVIQIHSGPVVKIGTMGPWLNVMDETFHLHLRTDHITELWAVRKPTADGHVTSVEGLDAKGE
MIIQFFGKRKEGSSERAEWRSLAEGLPRLKTVVAA

Sequences:

>Translated_355_residues
MTMTESMRPTPAEIRAYRAENPKLRERDIAAQLGISEAALVAAECGLTAIRIESSANRFLERAEELGEVLALTRNESAVH
EKVGLYENVKQGHAATLVLGSEIDLRVFPGAWEHGFAVTKTDAKGEVRRSLQFFDKWGNAVHKVHLRPASHLAAYEKLVE
DLRLDDQSQDFIADPGAPANDDVTDDSVDTAELRDRWSKLTDTHQFPGMLRKLKVGRRRALHSIGDDFAWRLDTASVETM
MRSAAETALPIMCFVGNRGVIQIHSGPVVKIGTMGPWLNVMDETFHLHLRTDHITELWAVRKPTADGHVTSVEGLDAKGE
MIIQFFGKRKEGSSERAEWRSLAEGLPRLKTVVAA
>Mature_354_residues
TMTESMRPTPAEIRAYRAENPKLRERDIAAQLGISEAALVAAECGLTAIRIESSANRFLERAEELGEVLALTRNESAVHE
KVGLYENVKQGHAATLVLGSEIDLRVFPGAWEHGFAVTKTDAKGEVRRSLQFFDKWGNAVHKVHLRPASHLAAYEKLVED
LRLDDQSQDFIADPGAPANDDVTDDSVDTAELRDRWSKLTDTHQFPGMLRKLKVGRRRALHSIGDDFAWRLDTASVETMM
RSAAETALPIMCFVGNRGVIQIHSGPVVKIGTMGPWLNVMDETFHLHLRTDHITELWAVRKPTADGHVTSVEGLDAKGEM
IIQFFGKRKEGSSERAEWRSLAEGLPRLKTVVAA

Specific function: Part of the binding-protein-dependent transport system for hemin [H]

COG id: COG3720

COG function: function code P; Putative heme degradation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To Y.enterocolitica hemS [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007845 [H]

Pfam domain/function: PF05171 HemS [H]

EC number: NA

Molecular weight: Translated: 39465; Mature: 39334

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTESMRPTPAEIRAYRAENPKLRERDIAAQLGISEAALVAAECGLTAIRIESSANRFL
CCCCCCCCCCHHHHHEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCEEEEEECHHHHHHH
ERAEELGEVLALTRNESAVHEKVGLYENVKQGHAATLVLGSEIDLRVFPGAWEHGFAVTK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCEEEEE
TDAKGEVRRSLQFFDKWGNAVHKVHLRPASHLAAYEKLVEDLRLDDQSQDFIADPGAPAN
CCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DDVTDDSVDTAELRDRWSKLTDTHQFPGMLRKLKVGRRRALHSIGDDFAWRLDTASVETM
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
MRSAAETALPIMCFVGNRGVIQIHSGPVVKIGTMGPWLNVMDETFHLHLRTDHITELWAV
HHHHHHHHCEEEEEECCCCEEEECCCCEEEECCCCCHHHHCCCEEEEEEEHHHHHHHHHH
RKPTADGHVTSVEGLDAKGEMIIQFFGKRKEGSSERAEWRSLAEGLPRLKTVVAA
CCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMTESMRPTPAEIRAYRAENPKLRERDIAAQLGISEAALVAAECGLTAIRIESSANRFL
CCCCCCCCCHHHHHEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCEEEEEECHHHHHHH
ERAEELGEVLALTRNESAVHEKVGLYENVKQGHAATLVLGSEIDLRVFPGAWEHGFAVTK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCEEEEE
TDAKGEVRRSLQFFDKWGNAVHKVHLRPASHLAAYEKLVEDLRLDDQSQDFIADPGAPAN
CCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DDVTDDSVDTAELRDRWSKLTDTHQFPGMLRKLKVGRRRALHSIGDDFAWRLDTASVETM
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
MRSAAETALPIMCFVGNRGVIQIHSGPVVKIGTMGPWLNVMDETFHLHLRTDHITELWAV
HHHHHHHHCEEEEEECCCCEEEECCCCEEEECCCCCHHHHCCCEEEEEEEHHHHHHHHHH
RKPTADGHVTSVEGLDAKGEMIIQFFGKRKEGSSERAEWRSLAEGLPRLKTVVAA
CCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]