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The map label for this gene is dppB [H]

Identifier: 150397525

GI number: 150397525

Start: 2405939

End: 2406982

Strand: Reverse

Name: dppB [H]

Synonym: Smed_2325

Alternate gene names: 150397525

Gene position: 2406982-2405939 (Counterclockwise)

Preceding gene: 150397526

Following gene: 150397524

Centisome position: 63.64

GC content: 62.16

Gene sequence:

>1044_bases
ATGAGCGGGCGCCGGCGCGCCCGTTCCCGGAAGGCGTTTGTCGCCGCGCTGCAGTTTCTCGTCGTCGTGGCAACCACCTA
TCTCGGCCTTCTCGCCGTCACCTTTTTCATCGGCCGCGTCATCCCGATCGATCCGGTGCTTGCCGTGCTCGGCGACCGCG
CGCCGAATCATGTCGTCGAGCGCACACGTGAGGCGATGGGTCTCAACCTGCCTCTCTACCAGCAGTTCTTCATCTACTGC
CGGCAAGCATTCACCGGCGATTTCGGGACTTCGGTGCTGACCACGAACCCGGTCATGGCGGACATACGCCGCGTCTTTCC
GGCGACCATGGAACTCGCGACGCTTGGAACGCTGATCGGTGCATTCATCGGCGTGCCTCTCGGCGTTCTCGCCGCTGTCA
AACGCGGCAGTATCGTCGACCAGATCGTTCGCGTCATCGGCCTCGTCGGCTATTCCGTGCCGATCTTCTGGCTGGCACTC
CTGGCGCTGCTGGTCTTCTATGCCCGGCTTCAATGGGTCGCCTATCCCGGCCGCATCGACATCGTCTACGAATACAGCTT
CACGCCCGCCACCGGTTTCTACCTCCTCGACTCGGCCTGGCAGGGGCAATGGGACGTTTTCCGCGACGTCTTCCGCCACA
TCATCCTGCCGGCCTCGCTGCTCGGTTACTTTTCGCTCGCCTATATCAGCCGCATGACCCGCAGCTTTATGCTGAACGAG
CTGCAGCAGGAATATATCGTCGCGGCACGCGCCAAAGGCCTTTCGGAGGCGCGAATCATCTGGTCTCATGCGCTACGCAA
CGCAGCGGTGCCGCTGGTGACGGTGATCGCCTTGTCCTATGCCGGTCTCCTCGAAGGGTCGGTTCTGACCGAGACGGTGT
TCGCCTGGCCGGGGCTCGGCCTCTACATCACCAATTCGTTGCAGAATGCCGATATGAACGCCGTTCTCGGCGGCACGATC
ATCATCGGATCGGTCTTCATCGGCATCAACCTCCTGTCCGATCTTCTCTACCGGACGCTGGACCCGAGGACGCGCGCCCG
ATGA

Upstream 100 bases:

>100_bases
GCTTCAAGCTCGGGCCGAGCTTCGACACCAACTACGTCTGGAACGTCTCCAAGGAATAGTCGAAAGGACCGTTCCCTTGA
GCATCATCGGAACAGAACCA

Downstream 100 bases:

>100_bases
GTCTTGCCCCCGTAACACGCCCCCCCGAAACACCCCCCGAAACACGCCCGATGTCGCGGCGCGAATGGCTGCTTTCCGAC
CGCCCCCAGTCGCGGACCCA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSGRRRARSRKAFVAALQFLVVVATTYLGLLAVTFFIGRVIPIDPVLAVLGDRAPNHVVERTREAMGLNLPLYQQFFIYC
RQAFTGDFGTSVLTTNPVMADIRRVFPATMELATLGTLIGAFIGVPLGVLAAVKRGSIVDQIVRVIGLVGYSVPIFWLAL
LALLVFYARLQWVAYPGRIDIVYEYSFTPATGFYLLDSAWQGQWDVFRDVFRHIILPASLLGYFSLAYISRMTRSFMLNE
LQQEYIVAARAKGLSEARIIWSHALRNAAVPLVTVIALSYAGLLEGSVLTETVFAWPGLGLYITNSLQNADMNAVLGGTI
IIGSVFIGINLLSDLLYRTLDPRTRAR

Sequences:

>Translated_347_residues
MSGRRRARSRKAFVAALQFLVVVATTYLGLLAVTFFIGRVIPIDPVLAVLGDRAPNHVVERTREAMGLNLPLYQQFFIYC
RQAFTGDFGTSVLTTNPVMADIRRVFPATMELATLGTLIGAFIGVPLGVLAAVKRGSIVDQIVRVIGLVGYSVPIFWLAL
LALLVFYARLQWVAYPGRIDIVYEYSFTPATGFYLLDSAWQGQWDVFRDVFRHIILPASLLGYFSLAYISRMTRSFMLNE
LQQEYIVAARAKGLSEARIIWSHALRNAAVPLVTVIALSYAGLLEGSVLTETVFAWPGLGLYITNSLQNADMNAVLGGTI
IIGSVFIGINLLSDLLYRTLDPRTRAR
>Mature_346_residues
SGRRRARSRKAFVAALQFLVVVATTYLGLLAVTFFIGRVIPIDPVLAVLGDRAPNHVVERTREAMGLNLPLYQQFFIYCR
QAFTGDFGTSVLTTNPVMADIRRVFPATMELATLGTLIGAFIGVPLGVLAAVKRGSIVDQIVRVIGLVGYSVPIFWLALL
ALLVFYARLQWVAYPGRIDIVYEYSFTPATGFYLLDSAWQGQWDVFRDVFRHIILPASLLGYFSLAYISRMTRSFMLNEL
QQEYIVAARAKGLSEARIIWSHALRNAAVPLVTVIALSYAGLLEGSVLTETVFAWPGLGLYITNSLQNADMNAVLGGTII
IGSVFIGINLLSDLLYRTLDPRTRAR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=41.4201183431953, Blast_Score=247, Evalue=8e-67,
Organism=Escherichia coli, GI1787761, Length=315, Percent_Identity=43.4920634920635, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1787550, Length=276, Percent_Identity=33.3333333333333, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=33.8607594936709, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787053, Length=315, Percent_Identity=32.3809523809524, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787497, Length=318, Percent_Identity=30.5031446540881, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788504, Length=290, Percent_Identity=27.5862068965517, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38393; Mature: 38262

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRRRARSRKAFVAALQFLVVVATTYLGLLAVTFFIGRVIPIDPVLAVLGDRAPNHVVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHH
RTREAMGLNLPLYQQFFIYCRQAFTGDFGTSVLTTNPVMADIRRVFPATMELATLGTLIG
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AFIGVPLGVLAAVKRGSIVDQIVRVIGLVGYSVPIFWLALLALLVFYARLQWVAYPGRID
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IVYEYSFTPATGFYLLDSAWQGQWDVFRDVFRHIILPASLLGYFSLAYISRMTRSFMLNE
EEEEECCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQQEYIVAARAKGLSEARIIWSHALRNAAVPLVTVIALSYAGLLEGSVLTETVFAWPGLG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
LYITNSLQNADMNAVLGGTIIIGSVFIGINLLSDLLYRTLDPRTRAR
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
SGRRRARSRKAFVAALQFLVVVATTYLGLLAVTFFIGRVIPIDPVLAVLGDRAPNHVVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHH
RTREAMGLNLPLYQQFFIYCRQAFTGDFGTSVLTTNPVMADIRRVFPATMELATLGTLIG
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AFIGVPLGVLAAVKRGSIVDQIVRVIGLVGYSVPIFWLALLALLVFYARLQWVAYPGRID
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IVYEYSFTPATGFYLLDSAWQGQWDVFRDVFRHIILPASLLGYFSLAYISRMTRSFMLNE
EEEEECCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQQEYIVAARAKGLSEARIIWSHALRNAAVPLVTVIALSYAGLLEGSVLTETVFAWPGLG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
LYITNSLQNADMNAVLGGTIIIGSVFIGINLLSDLLYRTLDPRTRAR
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]