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The map label for this gene is gsiC [H]

Identifier: 150397380

GI number: 150397380

Start: 2252422

End: 2253531

Strand: Direct

Name: gsiC [H]

Synonym: Smed_2179

Alternate gene names: 150397380

Gene position: 2252422-2253531 (Clockwise)

Preceding gene: 150397379

Following gene: 150397381

Centisome position: 59.56

GC content: 62.16

Gene sequence:

>1110_bases
ATGATGGAAAGCGGACCGATCACGGGTCCGGTCGCGACGGATGCGACCGCAGGCGAGACAGCCCTGCGGTCCTCCGATCT
TGCCGGTATCCCAGCCAAACCCAACCCGGCCGCGGAAGAGCGCGGCGGGACGATCTGGCAGCGCTTCGCCTTTCGCCGCC
CACTCGCCGCGCTGATCCTCCAGCGCCTTGGCTTGAGCGTCGGCTTGCTCTTTGCCGTATCGCTGATGATCTTCGGCGGC
ATCGAAGCCCTGCCCGGCGATTTCGCCACCACTTATCTCGGCCAATCGGCGACACCCCAGGCCGTCGAGAACATCCGCCA
GGATCTCGGGCTCGACCGCCCCTGGAGCGAGCGCTATCTCAGTTGGCTCGGCGGTGCCGTTCAAGGCGATTTCGGCACCT
CATGGGCAAGCAGGAACTCCGTCAGCGAACAGATAGGCAATCGCCTCGGCAACTCGCTCTTCCTCGCCTTCTTCGCGGCG
CTCGTCTCCGTGCCGCTCGCGGTGGGACTTGGAATGCTCGCGGTGCAATTCCGAAATCGCCTGCCGGACAAGATCATCAA
TGTGATATCGCTCGCGGCGATTTCGCTGCCGGAGTTTTTCATCGGCTATCTGCTGATCATGTACTTCGCCGTCGAATGGG
GCGTAGCCACCTTTCCCGCGACCGTCTATAACGGCATGGGCTTTACCGATCGGCTTTCGGCGATCGCACTTCCGGTCGCA
ACCCTCGTGCTGGTGGTTCTCGCTCATATGATGCGCATGACGCGCGCGGCGATCCTCAACGTCATGTCCTCGGCCTATGT
GGAGACAGCCGAACTCAAGGGCCTCGGCACGTTCCGCATCATCGCGCGCCACGCCGCCCCCAACGCCGTGGCGCCTGTCA
TCAACGTCATCGCGTTGAACCTTGCCTATCTCGTCGTCGGCGTGGTCGTCGTCGAGGTCGTCTTCGTCTATCCCGGCATG
GGGCAATATATGGTGGATGCCGTAACGGTGCGCGATATGCCCGTCGTGCAGGCATGCGGGCTGATCTTTGCGGCCTTCTA
TATCTTCCTCAACATGGCGGCAGACATTCTCGCCATTCTCGCCAATCCGAGATTGAGGCATCCGCGATGA

Upstream 100 bases:

>100_bases
TCGTGAACGCGGCCGGCAAGACGGTGAAGGGCTATGTCCACGACATCGGCAACGACATGTCCAACGGCTATGTCGCGACC
AGGGTATGGCTGGACGCCTG

Downstream 100 bases:

>100_bases
ACTTGAGAACCATACCCTTCAGTGCCTGGATCGGCATCATCGGCATTGCTATCGCAATTTTCTGCGCCCTCTTTGCTCCC
CTTCTCGCCCCCTTTGGCGA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MMESGPITGPVATDATAGETALRSSDLAGIPAKPNPAAEERGGTIWQRFAFRRPLAALILQRLGLSVGLLFAVSLMIFGG
IEALPGDFATTYLGQSATPQAVENIRQDLGLDRPWSERYLSWLGGAVQGDFGTSWASRNSVSEQIGNRLGNSLFLAFFAA
LVSVPLAVGLGMLAVQFRNRLPDKIINVISLAAISLPEFFIGYLLIMYFAVEWGVATFPATVYNGMGFTDRLSAIALPVA
TLVLVVLAHMMRMTRAAILNVMSSAYVETAELKGLGTFRIIARHAAPNAVAPVINVIALNLAYLVVGVVVVEVVFVYPGM
GQYMVDAVTVRDMPVVQACGLIFAAFYIFLNMAADILAILANPRLRHPR

Sequences:

>Translated_369_residues
MMESGPITGPVATDATAGETALRSSDLAGIPAKPNPAAEERGGTIWQRFAFRRPLAALILQRLGLSVGLLFAVSLMIFGG
IEALPGDFATTYLGQSATPQAVENIRQDLGLDRPWSERYLSWLGGAVQGDFGTSWASRNSVSEQIGNRLGNSLFLAFFAA
LVSVPLAVGLGMLAVQFRNRLPDKIINVISLAAISLPEFFIGYLLIMYFAVEWGVATFPATVYNGMGFTDRLSAIALPVA
TLVLVVLAHMMRMTRAAILNVMSSAYVETAELKGLGTFRIIARHAAPNAVAPVINVIALNLAYLVVGVVVVEVVFVYPGM
GQYMVDAVTVRDMPVVQACGLIFAAFYIFLNMAADILAILANPRLRHPR
>Mature_369_residues
MMESGPITGPVATDATAGETALRSSDLAGIPAKPNPAAEERGGTIWQRFAFRRPLAALILQRLGLSVGLLFAVSLMIFGG
IEALPGDFATTYLGQSATPQAVENIRQDLGLDRPWSERYLSWLGGAVQGDFGTSWASRNSVSEQIGNRLGNSLFLAFFAA
LVSVPLAVGLGMLAVQFRNRLPDKIINVISLAAISLPEFFIGYLLIMYFAVEWGVATFPATVYNGMGFTDRLSAIALPVA
TLVLVVLAHMMRMTRAAILNVMSSAYVETAELKGLGTFRIIARHAAPNAVAPVINVIALNLAYLVVGVVVVEVVFVYPGM
GQYMVDAVTVRDMPVVQACGLIFAAFYIFLNMAADILAILANPRLRHPR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=310, Percent_Identity=36.7741935483871, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1789965, Length=335, Percent_Identity=31.3432835820896, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789888, Length=313, Percent_Identity=33.2268370607029, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787761, Length=274, Percent_Identity=33.2116788321168, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=28.0254777070064, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=26.4705882352941, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788504, Length=282, Percent_Identity=27.6595744680851, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 39592; Mature: 39592

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCC
>Mature Secondary Structure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CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]