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The map label for this gene is ribH2 [H]

Identifier: 150397339

GI number: 150397339

Start: 2205159

End: 2205686

Strand: Direct

Name: ribH2 [H]

Synonym: Smed_2138

Alternate gene names: 150397339

Gene position: 2205159-2205686 (Clockwise)

Preceding gene: 150397338

Following gene: 150397340

Centisome position: 58.31

GC content: 60.61

Gene sequence:

>528_bases
ATGTTCGCCCGACGGGATCCTTGGAAAAATGCCAACCCTGAAAGGCTTGAGACAATGACAGTAGTTTCCCACCCCTCCGC
TAAGATTGCGATCGTTCGCGCCCGCTGGCACGCCGATATCGTCGACCGTTGCGTCGATGCTTTCGTCGCGCAATGGACGA
AGCTTGGCGGCAACGCTATCGATGTCGAGGTCTTTGACGTGCCCGGCGCGCTCGAAATCCCGCTGCATGCGCAAAAGCTT
GCGAAGACTGGCCGCTATGCAGCGATCCTCGGCACCGCGTTTGTCGTCAATGGCGGCATCTATCGCCACGACTTCGTCGC
CGGCACGGTGCTCGACGGCATGATGCGCGTGCAGCTCGATACGGACGTGCCGGTGCTCTCGGCGGTGCTTACACCTCACA
ATTTCCAGGAAAGCGAGCCGCTGATCGCCTTCTTCCGCGACCACTTCGTCGTCAAGGGAGAGGAAGCCGCAAATGCCTGC
GCGCAGATTCTCGATGCACGGGCGAAGCTGGCGCTGGTGAACGCCTGA

Upstream 100 bases:

>100_bases
AAGGTCAGCAGATCCGGTCAAACTCCGGAGCCGACGGTTATAGTCCGGATGGAAGAGAGCAAGCAGAAGCGTCGCCCCTC
CCCGGGGTTTTCGCACATGC

Downstream 100 bases:

>100_bases
CGGAAACTGCCCCTCTCCTCGGATTTAACCCGAGGAGAGGGCCAACTCGAGGTCGCTGAACGGCGATTGAAACGCCGCGC
GATCGGCGATAGATAAACTT

Product: riboflavin synthase subunit beta

Products: NA

Alternate protein names: DMRL synthase 2; Lumazine synthase 2; Riboflavin synthase 2 beta chain [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MFARRDPWKNANPERLETMTVVSHPSAKIAIVRARWHADIVDRCVDAFVAQWTKLGGNAIDVEVFDVPGALEIPLHAQKL
AKTGRYAAILGTAFVVNGGIYRHDFVAGTVLDGMMRVQLDTDVPVLSAVLTPHNFQESEPLIAFFRDHFVVKGEEAANAC
AQILDARAKLALVNA

Sequences:

>Translated_175_residues
MFARRDPWKNANPERLETMTVVSHPSAKIAIVRARWHADIVDRCVDAFVAQWTKLGGNAIDVEVFDVPGALEIPLHAQKL
AKTGRYAAILGTAFVVNGGIYRHDFVAGTVLDGMMRVQLDTDVPVLSAVLTPHNFQESEPLIAFFRDHFVVKGEEAANAC
AQILDARAKLALVNA
>Mature_175_residues
MFARRDPWKNANPERLETMTVVSHPSAKIAIVRARWHADIVDRCVDAFVAQWTKLGGNAIDVEVFDVPGALEIPLHAQKL
AKTGRYAAILGTAFVVNGGIYRHDFVAGTVLDGMMRVQLDTDVPVLSAVLTPHNFQESEPLIAFFRDHFVVKGEEAANAC
AQILDARAKLALVNA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=118, Percent_Identity=33.8983050847458, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 19188; Mature: 19188

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFARRDPWKNANPERLETMTVVSHPSAKIAIVRARWHADIVDRCVDAFVAQWTKLGGNAI
CCCCCCCCCCCCHHHHEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEE
DVEVFDVPGALEIPLHAQKLAKTGRYAAILGTAFVVNGGIYRHDFVAGTVLDGMMRVQLD
EEEEEECCCCEECCCHHHHHHHCCCCHHHHHHHHEECCCEEEHHHHHHHHHHCEEEEEEC
TDVPVLSAVLTPHNFQESEPLIAFFRDHFVVKGEEAANACAQILDARAKLALVNA
CCCHHHHHHHCCCCCCCCCCCEEEEECCEEEECHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MFARRDPWKNANPERLETMTVVSHPSAKIAIVRARWHADIVDRCVDAFVAQWTKLGGNAI
CCCCCCCCCCCCHHHHEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEE
DVEVFDVPGALEIPLHAQKLAKTGRYAAILGTAFVVNGGIYRHDFVAGTVLDGMMRVQLD
EEEEEECCCCEECCCHHHHHHHCCCCHHHHHHHHEECCCEEEHHHHHHHHHHCEEEEEEC
TDVPVLSAVLTPHNFQESEPLIAFFRDHFVVKGEEAANACAQILDARAKLALVNA
CCCHHHHHHHCCCCCCCCCCCEEEEECCEEEECHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]