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The map label for this gene is glnA [H]

Identifier: 150397331

GI number: 150397331

Start: 2195785

End: 2197149

Strand: Reverse

Name: glnA [H]

Synonym: Smed_2130

Alternate gene names: 150397331

Gene position: 2197149-2195785 (Counterclockwise)

Preceding gene: 150397332

Following gene: 150397330

Centisome position: 58.1

GC content: 60.73

Gene sequence:

>1365_bases
ATGAGCTATTCGTTCGACGAACTGAAAGAGGATGTGGCCGAGGGCCGCATCGACACGGTGCTCGCCTGCCAGGTGGATAT
GCAGGGCCGTTTGATGGGAAAGCGTTTTCACGCGGAATACTTCGTGGAAAGTGCGTGGAAGGAAACGCATAGCTGCAATT
ACCTGCTCGCGACAGATATGGAAATGGAGACGGTGCCCGGTTACAAGGCGACGAGCTGGGACAAAGGTTACGGCGACTAC
ACCATGAAGCCGGACCTTTCGACGCTTCGGCGCATTCCGTGGCTCGACGGCACGGCGCTGGTTCTCTGCGACATGCTGGA
CCATCACACGCATGCGGAGGTGCCGCATTCGCCGCGCGCCATCTTGAAGGCGCAGGTATCGCGCCTCGAAGCCATGGGCT
TCAAAGCCTTCATGGCAAGCGAACTCGAATTCTTCCTCTTCGATCAGTCCTACGACGATGCGAGGCTCTCCGGATACCGC
GATCTGCAGCTCGCAAGCGGCTACAACGAGGATTACCACATCTTCCAGACGACCAAGGAAGAGGACGTGATGCGTGCGAT
CCGCAACGGTCTTCAGGGCGCCGGCATCCCGGTCGAGAATTCCAAGGGCGAGGCGTCCGCGGGCCAGGAAGAGATCAATG
TCCGCTACGCCGAGGCCGTGACCATGGCCGACCGGCACGCGATCATCAAAAACGGCTGCAAGGAAATTGCGTGGCAGCGC
GGCAAGGCGATCACCTTCCTTGCCAAGTGGAACTACTCGGCCGCCGGCTCCTCGTCCCATATCCACCAGTCGCTCTGGAG
CAAGGACGGCGAAAAGCCGCTGTTCTTCGACAAGGACGGGCAGTACGGCATGTCCGACCTCATGCGCCATTATGTGGCCG
GTCAACTCGCCCATGCGAGCGAGGTCACCTATTTCCTGGCGCCTTACATCAATTCCTACAAGCGCTTCATGGCGGGTACT
TTCGCTCCGACCAAGGCCATCTGGAGCAAGGACAACCGCACCGCCGGCTATCGTCTCTGCGGCGAAGGCAGCAAGGCGAT
CCGGATCGAATGCCGCGTCGGCGGCTCCGACCTCAATCCCTATCTCGCCTTCGCCGCTTTGATCGCGGCCGGCATATCGG
GCATCGAGAACAAGATGGAGCTGGAGGCTCCCTTCGTCGGCGATGCCTATCACGGCAAGGACGTGCGCGAGGTTCCGCAT
ACGCTGAGGGCCGCGACCGAGGCACTGAGCGGATCGAAATTGCTGCGCGCCGCCTTCGGCGAGGAGGTGATCGACCATTA
TGTGCATGCGGCAGAATGGGAGCAGCAGGAATATGATCGGCGGGTCACCGATTGGGAGGTCGCGCGCGGGTTCGAGCGGG
CATAG

Upstream 100 bases:

>100_bases
GGCGAAGCGTAAGCAGTAGAGGAGAGTGGGATCGCGCGCGGTCCCACTCCGCTTCGCGGTACGAGGGAACGACCGCACCT
AAACATGGGACGACACTTTC

Downstream 100 bases:

>100_bases
AAGTTTGCGGCTTTATCTCTCCGCAATCCCTCCTCACAGGGGGGAGGGATTCATTGTGAAATGAAAACAGGAAGACGATC
ATGACGATGATCAGATGCAT

Product: glutamine synthetase catalytic subunit

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSYSFDELKEDVAEGRIDTVLACQVDMQGRLMGKRFHAEYFVESAWKETHSCNYLLATDMEMETVPGYKATSWDKGYGDY
TMKPDLSTLRRIPWLDGTALVLCDMLDHHTHAEVPHSPRAILKAQVSRLEAMGFKAFMASELEFFLFDQSYDDARLSGYR
DLQLASGYNEDYHIFQTTKEEDVMRAIRNGLQGAGIPVENSKGEASAGQEEINVRYAEAVTMADRHAIIKNGCKEIAWQR
GKAITFLAKWNYSAAGSSSHIHQSLWSKDGEKPLFFDKDGQYGMSDLMRHYVAGQLAHASEVTYFLAPYINSYKRFMAGT
FAPTKAIWSKDNRTAGYRLCGEGSKAIRIECRVGGSDLNPYLAFAALIAAGISGIENKMELEAPFVGDAYHGKDVREVPH
TLRAATEALSGSKLLRAAFGEEVIDHYVHAAEWEQQEYDRRVTDWEVARGFERA

Sequences:

>Translated_454_residues
MSYSFDELKEDVAEGRIDTVLACQVDMQGRLMGKRFHAEYFVESAWKETHSCNYLLATDMEMETVPGYKATSWDKGYGDY
TMKPDLSTLRRIPWLDGTALVLCDMLDHHTHAEVPHSPRAILKAQVSRLEAMGFKAFMASELEFFLFDQSYDDARLSGYR
DLQLASGYNEDYHIFQTTKEEDVMRAIRNGLQGAGIPVENSKGEASAGQEEINVRYAEAVTMADRHAIIKNGCKEIAWQR
GKAITFLAKWNYSAAGSSSHIHQSLWSKDGEKPLFFDKDGQYGMSDLMRHYVAGQLAHASEVTYFLAPYINSYKRFMAGT
FAPTKAIWSKDNRTAGYRLCGEGSKAIRIECRVGGSDLNPYLAFAALIAAGISGIENKMELEAPFVGDAYHGKDVREVPH
TLRAATEALSGSKLLRAAFGEEVIDHYVHAAEWEQQEYDRRVTDWEVARGFERA
>Mature_453_residues
SYSFDELKEDVAEGRIDTVLACQVDMQGRLMGKRFHAEYFVESAWKETHSCNYLLATDMEMETVPGYKATSWDKGYGDYT
MKPDLSTLRRIPWLDGTALVLCDMLDHHTHAEVPHSPRAILKAQVSRLEAMGFKAFMASELEFFLFDQSYDDARLSGYRD
LQLASGYNEDYHIFQTTKEEDVMRAIRNGLQGAGIPVENSKGEASAGQEEINVRYAEAVTMADRHAIIKNGCKEIAWQRG
KAITFLAKWNYSAAGSSSHIHQSLWSKDGEKPLFFDKDGQYGMSDLMRHYVAGQLAHASEVTYFLAPYINSYKRFMAGTF
APTKAIWSKDNRTAGYRLCGEGSKAIRIECRVGGSDLNPYLAFAALIAAGISGIENKMELEAPFVGDAYHGKDVREVPHT
LRAATEALSGSKLLRAAFGEEVIDHYVHAAEWEQQEYDRRVTDWEVARGFERA

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=447, Percent_Identity=26.6219239373602, Blast_Score=151, Evalue=1e-36,
Organism=Escherichia coli, GI87081870, Length=448, Percent_Identity=28.3482142857143, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790301, Length=403, Percent_Identity=30.272952853598, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 51087; Mature: 50956

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSFDELKEDVAEGRIDTVLACQVDMQGRLMGKRFHAEYFVESAWKETHSCNYLLATDM
CCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
EMETVPGYKATSWDKGYGDYTMKPDLSTLRRIPWLDGTALVLCDMLDHHTHAEVPHSPRA
CHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHH
ILKAQVSRLEAMGFKAFMASELEFFLFDQSYDDARLSGYRDLQLASGYNEDYHIFQTTKE
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHCCCCCEEECCCCCCCEEEEECCCH
EDVMRAIRNGLQGAGIPVENSKGEASAGQEEINVRYAEAVTMADRHAIIKNGCKEIAWQR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHCC
GKAITFLAKWNYSAAGSSSHIHQSLWSKDGEKPLFFDKDGQYGMSDLMRHYVAGQLAHAS
CCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
EVTYFLAPYINSYKRFMAGTFAPTKAIWSKDNRTAGYRLCGEGSKAIRIECRVGGSDLNP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCCCEEEEEEEECCCCCCH
YLAFAALIAAGISGIENKMELEAPFVGDAYHGKDVREVPHTLRAATEALSGSKLLRAAFG
HHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
EEVIDHYVHAAEWEQQEYDRRVTDWEVARGFERA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
>Mature Secondary Structure 
SYSFDELKEDVAEGRIDTVLACQVDMQGRLMGKRFHAEYFVESAWKETHSCNYLLATDM
CCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
EMETVPGYKATSWDKGYGDYTMKPDLSTLRRIPWLDGTALVLCDMLDHHTHAEVPHSPRA
CHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHH
ILKAQVSRLEAMGFKAFMASELEFFLFDQSYDDARLSGYRDLQLASGYNEDYHIFQTTKE
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHCCCCCEEECCCCCCCEEEEECCCH
EDVMRAIRNGLQGAGIPVENSKGEASAGQEEINVRYAEAVTMADRHAIIKNGCKEIAWQR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHCC
GKAITFLAKWNYSAAGSSSHIHQSLWSKDGEKPLFFDKDGQYGMSDLMRHYVAGQLAHAS
CCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
EVTYFLAPYINSYKRFMAGTFAPTKAIWSKDNRTAGYRLCGEGSKAIRIECRVGGSDLNP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCCCEEEEEEEECCCCCCH
YLAFAALIAAGISGIENKMELEAPFVGDAYHGKDVREVPHTLRAATEALSGSKLLRAAFG
HHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
EEVIDHYVHAAEWEQQEYDRRVTDWEVARGFERA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1348781; 10360571 [H]