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The map label for this gene is dsdA

Identifier: 150397293

GI number: 150397293

Start: 2151601

End: 2152929

Strand: Reverse

Name: dsdA

Synonym: Smed_2092

Alternate gene names: 150397293

Gene position: 2152929-2151601 (Counterclockwise)

Preceding gene: 150397294

Following gene: 150397292

Centisome position: 56.93

GC content: 61.32

Gene sequence:

>1329_bases
ATGACACTTCAGCTCCCGAATGATCCGGCCCGTAGCGATGTGCTTTCAGCCCGCCCGACCCTTTGGATCAATTCTCTGTA
CCGCGACGATGCAATCGGCGATACCTGCCTGCCGCTCGTTCCCGATCAGGTCGATGTGGCACAGTCTGACTGGGAGCGCC
TGGCGCCGCTCCTCGAGACCTGTTTCCCCGAATTGAAGAAGACAGCGGGTGCAATACGCTCCGACCTGACAGAATTGCAC
GCGCTTCGTGAGGCGCTTGGTTATGGCGGCGGCGAGTTCGGCCGGGTCTTCGCTAAGGCAGACAGCGCGCTCCCGGTAGC
GGGTTCGATCAAGGCACGCGGCGGCGTCTACGAAGTCTTCGTTTTCGCCGAAGAACTGGCCAGGCGCGAGGGCCTTATCG
GGGACCGGGAGGATATTCGTCATCTGGCCAGCGCCGAAGCCCGGGCATTTTTCTCCAGCTATTCGATCGCCGTAGGCAGC
ACTGGCAATCTGGGGCTCAGCGTTGGAGTCGCCGCGCGTGCTCTTGGCTTCGAAGCAACGGTTCACATGTCATCGGATGC
GAAACCGTGGAAGGTGGAGCGATTGAGAAAGCTCGGCGTGAAGGTCGTACAGCACGAGGCCGACTACACCACGGCGGTGG
AGAACGCCCGCAGCGCGGCAGAGGACGACCCGGCGGTCTACTTCGTCGACGATGAGCAATCCCGACGCCTGTTTCTCGGT
TACAGCGTTGCCGCGTCGGAACTCGTGGATCAGCTTCAAACGTTTGGTGTTGCCGTCGACGCCGACCGTCCTCTGTTCCT
TTATCTGCCTTGCGGCATCGGCGGTGCCCCCGGCGGCGTGACCTATGGTGCCAAAAAGGTGTTCGGCGACAATGCGCATT
GCTTCTTTGTGGAGCCTGTCCAGTCGCCTTGCGCTCTCGTCCATATGATGAGTGGTTCCGAGGAACTCGTCTCGGTCTAT
GATGTCGGGCTGACGAACAGCACGGAGGCGGACGGCATGGCCGTCGCGCGGATGTCGGCCTTCGTTGCGACAGTCATGCG
GAACATGCTGGCAGGGGTCTTCACCGTTGACGATGCGTCTCTCTTTCGCTGGCTGCTCCTTGCCCACGAGGTCCAGGGTC
TTCGCCTGGAGCCTTCTGCGGCCGCGGGTTTTGCGGGGCCGGGCTTTATCGTGAAGCATCCGCAGGGGCGGGCATTCTGC
GAACGGCTGAAGCTGTCTGATCGCTTGCGGCAGGCAACGCATGTGGTCTGGACGACAGGAGGATCGTTTGTGCCGCAGGA
GCAGTTCGACCAATTCCTGGAAATTGCTCAGGCCTCCAGATCACGATGA

Upstream 100 bases:

>100_bases
GCAAGCTGGAGATCGATGCCACCGATCTCGCCATTGCCAGGTATGGCTAAGCGACTCCAGCGCGAGCAGCATTCGTAGCC
CCCCAAAACACGAGGACGAC

Downstream 100 bases:

>100_bases
TTTACAGCAGTACCGATTTCTCTGGCGCTAGCCGCCACGGTCGTTTAATGAGCCTCTGCCAGTTGGCCGGGCAGCCGCGC
CCCGCAAGTGCCGAAAGGCC

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTLQLPNDPARSDVLSARPTLWINSLYRDDAIGDTCLPLVPDQVDVAQSDWERLAPLLETCFPELKKTAGAIRSDLTELH
ALREALGYGGGEFGRVFAKADSALPVAGSIKARGGVYEVFVFAEELARREGLIGDREDIRHLASAEARAFFSSYSIAVGS
TGNLGLSVGVAARALGFEATVHMSSDAKPWKVERLRKLGVKVVQHEADYTTAVENARSAAEDDPAVYFVDDEQSRRLFLG
YSVAASELVDQLQTFGVAVDADRPLFLYLPCGIGGAPGGVTYGAKKVFGDNAHCFFVEPVQSPCALVHMMSGSEELVSVY
DVGLTNSTEADGMAVARMSAFVATVMRNMLAGVFTVDDASLFRWLLLAHEVQGLRLEPSAAAGFAGPGFIVKHPQGRAFC
ERLKLSDRLRQATHVVWTTGGSFVPQEQFDQFLEIAQASRSR

Sequences:

>Translated_442_residues
MTLQLPNDPARSDVLSARPTLWINSLYRDDAIGDTCLPLVPDQVDVAQSDWERLAPLLETCFPELKKTAGAIRSDLTELH
ALREALGYGGGEFGRVFAKADSALPVAGSIKARGGVYEVFVFAEELARREGLIGDREDIRHLASAEARAFFSSYSIAVGS
TGNLGLSVGVAARALGFEATVHMSSDAKPWKVERLRKLGVKVVQHEADYTTAVENARSAAEDDPAVYFVDDEQSRRLFLG
YSVAASELVDQLQTFGVAVDADRPLFLYLPCGIGGAPGGVTYGAKKVFGDNAHCFFVEPVQSPCALVHMMSGSEELVSVY
DVGLTNSTEADGMAVARMSAFVATVMRNMLAGVFTVDDASLFRWLLLAHEVQGLRLEPSAAAGFAGPGFIVKHPQGRAFC
ERLKLSDRLRQATHVVWTTGGSFVPQEQFDQFLEIAQASRSR
>Mature_441_residues
TLQLPNDPARSDVLSARPTLWINSLYRDDAIGDTCLPLVPDQVDVAQSDWERLAPLLETCFPELKKTAGAIRSDLTELHA
LREALGYGGGEFGRVFAKADSALPVAGSIKARGGVYEVFVFAEELARREGLIGDREDIRHLASAEARAFFSSYSIAVGST
GNLGLSVGVAARALGFEATVHMSSDAKPWKVERLRKLGVKVVQHEADYTTAVENARSAAEDDPAVYFVDDEQSRRLFLGY
SVAASELVDQLQTFGVAVDADRPLFLYLPCGIGGAPGGVTYGAKKVFGDNAHCFFVEPVQSPCALVHMMSGSEELVSVYD
VGLTNSTEADGMAVARMSAFVATVMRNMLAGVFTVDDASLFRWLLLAHEVQGLRLEPSAAAGFAGPGFIVKHPQGRAFCE
RLKLSDRLRQATHVVWTTGGSFVPQEQFDQFLEIAQASRSR

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=430, Percent_Identity=46.2790697674419, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_SINMW (A6UB95)

Other databases:

- EMBL:   CP000738
- RefSeq:   YP_001327760.1
- STRING:   A6UB95
- GeneID:   5322952
- GenomeReviews:   CP000738_GR
- KEGG:   smd:Smed_2092
- eggNOG:   COG3048
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- ProtClustDB:   PRK02991
- BioCyc:   SMED366394:SMED_2092-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 47800; Mature: 47668

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQLPNDPARSDVLSARPTLWINSLYRDDAIGDTCLPLVPDQVDVAQSDWERLAPLLET
CEECCCCCCCHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
CFPELKKTAGAIRSDLTELHALREALGYGGGEFGRVFAKADSALPVAGSIKARGGVYEVF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEHHH
VFAEELARREGLIGDREDIRHLASAEARAFFSSYSIAVGSTGNLGLSVGVAARALGFEAT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCCCCEEHHHHHHHHCCEEE
VHMSSDAKPWKVERLRKLGVKVVQHEADYTTAVENARSAAEDDPAVYFVDDEQSRRLFLG
EEECCCCCCHHHHHHHHHCHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEE
YSVAASELVDQLQTFGVAVDADRPLFLYLPCGIGGAPGGVTYGAKKVFGDNAHCFFVEPV
HHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCEEEEECCC
QSPCALVHMMSGSEELVSVYDVGLTNSTEADGMAVARMSAFVATVMRNMLAGVFTVDDAS
CCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECHHH
LFRWLLLAHEVQGLRLEPSAAAGFAGPGFIVKHPQGRAFCERLKLSDRLRQATHVVWTTG
HHHHHHHHHHHCCCEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHEEEEECC
GSFVPQEQFDQFLEIAQASRSR
CCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLQLPNDPARSDVLSARPTLWINSLYRDDAIGDTCLPLVPDQVDVAQSDWERLAPLLET
EECCCCCCCHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
CFPELKKTAGAIRSDLTELHALREALGYGGGEFGRVFAKADSALPVAGSIKARGGVYEVF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEHHH
VFAEELARREGLIGDREDIRHLASAEARAFFSSYSIAVGSTGNLGLSVGVAARALGFEAT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCCCCEEHHHHHHHHCCEEE
VHMSSDAKPWKVERLRKLGVKVVQHEADYTTAVENARSAAEDDPAVYFVDDEQSRRLFLG
EEECCCCCCHHHHHHHHHCHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEE
YSVAASELVDQLQTFGVAVDADRPLFLYLPCGIGGAPGGVTYGAKKVFGDNAHCFFVEPV
HHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCEEEEECCC
QSPCALVHMMSGSEELVSVYDVGLTNSTEADGMAVARMSAFVATVMRNMLAGVFTVDDAS
CCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECHHH
LFRWLLLAHEVQGLRLEPSAAAGFAGPGFIVKHPQGRAFCERLKLSDRLRQATHVVWTTG
HHHHHHHHHHHCCCEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHEEEEECC
GSFVPQEQFDQFLEIAQASRSR
CCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA