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The map label for this gene is murB [H]

Identifier: 150397281

GI number: 150397281

Start: 2136445

End: 2137419

Strand: Reverse

Name: murB [H]

Synonym: Smed_2080

Alternate gene names: 150397281

Gene position: 2137419-2136445 (Counterclockwise)

Preceding gene: 150397282

Following gene: 150397279

Centisome position: 56.52

GC content: 60.82

Gene sequence:

>975_bases
ATGAAACAGGTCAACGGGCAGAAACTCCTCGAATCGCTCGGAAACGGCGTCAGCGCGATACGCGGGCGTATCACGCCCGA
TGCCCCAATGGACCGCGTTACCTGGTTTCGGGCAGGCGGTCTCGCCGAACTGATGTTTCAGCCGCACGACACGGACGATC
TCACTACCTTCCTCAAGCTCGTGCCTGAGGAGGTGCCGGTGCTGGTCGTCGGTGTGGGCTCCAACCTGCTCGTGCGCGAC
GGAGGTATTCCCGGTGTCGTCATCCGGCTCTCGGCAAAGGGCTTCGGCGACCTCGAACTTGCCGGTGAACACCGCATCAA
GGCGGGCGCAATCTGCCCCGACAAGAACCTCGCCGCCATGGCGCTCGACCACGGCATAGGCGGCTTCTATTTCTATTACG
GCATTCCTGGTTCGATCGGCGGTGCACTGCGCATGAACGCCGGCGCCAATGCCGGTGAAACCAGCGCGCGCGTCCTCGAA
GTCCATGCCGTCGACCGGAAGGGCGACAGACATGTTCTGAGCAAATCGGAGATGGGCTATGGCTATCGCCATTCAGGGGC
AGCCAAGGACCTGATCTTCACGCATGCGATCTTCGAAGGCTATGCAGAGGACAAGGCCAAGATCCGCAACGACATGGACG
CGGTGCGCCAGCATCGGGAAACCGTACAGCCGATCCGCGAAAAGACCGGCGGCTCCACTTTCAAGAACCCGGAAGGCCAT
TCGGCCTGGAAGTTGATCGACGAGGCCGGCTGCCGCGGCATGATGATCGGCAACGCTCAGATGTCCCCGCTTCACTGCAA
TTTCATGATCAATACCGGTCAGGCGACCGGCTATGAACTGGAATATCTCGGCGAGACCGTCCGCCAGCGGGTGATGGACC
ATTCCGGTGTCAAGCTGGAATGGGAGATCAAGCGCGTCGGCAATTTCATGCCGGGCTACGAAATCAAGGAATTCCTCGGC
CGCGCTACGGCCTGA

Upstream 100 bases:

>100_bases
CGCAGCCGGGCGATTTTGTGGTTCTCTTGGGGGCTGGCAGCATTACCTATTGGGCCGCGGCGCTGCCGAAGCAGCTCGCG
GAAATCTCGGGAAATCGAGC

Downstream 100 bases:

>100_bases
AGCGAATCAGCGCCAAAGAGGGGCCCGCGACGGACATCCGCCGCGGCCCTGTTTTCAGGTTCATTCCTCCTCAGCCCGAG
ACCTCTTCCTCGTTCGAAAG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKQVNGQKLLESLGNGVSAIRGRITPDAPMDRVTWFRAGGLAELMFQPHDTDDLTTFLKLVPEEVPVLVVGVGSNLLVRD
GGIPGVVIRLSAKGFGDLELAGEHRIKAGAICPDKNLAAMALDHGIGGFYFYYGIPGSIGGALRMNAGANAGETSARVLE
VHAVDRKGDRHVLSKSEMGYGYRHSGAAKDLIFTHAIFEGYAEDKAKIRNDMDAVRQHRETVQPIREKTGGSTFKNPEGH
SAWKLIDEAGCRGMMIGNAQMSPLHCNFMINTGQATGYELEYLGETVRQRVMDHSGVKLEWEIKRVGNFMPGYEIKEFLG
RATA

Sequences:

>Translated_324_residues
MKQVNGQKLLESLGNGVSAIRGRITPDAPMDRVTWFRAGGLAELMFQPHDTDDLTTFLKLVPEEVPVLVVGVGSNLLVRD
GGIPGVVIRLSAKGFGDLELAGEHRIKAGAICPDKNLAAMALDHGIGGFYFYYGIPGSIGGALRMNAGANAGETSARVLE
VHAVDRKGDRHVLSKSEMGYGYRHSGAAKDLIFTHAIFEGYAEDKAKIRNDMDAVRQHRETVQPIREKTGGSTFKNPEGH
SAWKLIDEAGCRGMMIGNAQMSPLHCNFMINTGQATGYELEYLGETVRQRVMDHSGVKLEWEIKRVGNFMPGYEIKEFLG
RATA
>Mature_324_residues
MKQVNGQKLLESLGNGVSAIRGRITPDAPMDRVTWFRAGGLAELMFQPHDTDDLTTFLKLVPEEVPVLVVGVGSNLLVRD
GGIPGVVIRLSAKGFGDLELAGEHRIKAGAICPDKNLAAMALDHGIGGFYFYYGIPGSIGGALRMNAGANAGETSARVLE
VHAVDRKGDRHVLSKSEMGYGYRHSGAAKDLIFTHAIFEGYAEDKAKIRNDMDAVRQHRETVQPIREKTGGSTFKNPEGH
SAWKLIDEAGCRGMMIGNAQMSPLHCNFMINTGQATGYELEYLGETVRQRVMDHSGVKLEWEIKRVGNFMPGYEIKEFLG
RATA

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 35316; Mature: 35316

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVNGQKLLESLGNGVSAIRGRITPDAPMDRVTWFRAGGLAELMFQPHDTDDLTTFLKL
CCCCCHHHHHHHHCCCHHHHHCCCCCCCCCHHHHEEECCCCEEEEECCCCCHHHHHHHHH
VPEEVPVLVVGVGSNLLVRDGGIPGVVIRLSAKGFGDLELAGEHRIKAGAICPDKNLAAM
CCCCCCEEEEECCCCEEEECCCCCEEEEEEECCCCCCEEECCCCCEEECCCCCCCCCEEE
ALDHGIGGFYFYYGIPGSIGGALRMNAGANAGETSARVLEVHAVDRKGDRHVLSKSEMGY
EECCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCEEEEEEEEECCCCCCHHHCHHCCCC
GYRHSGAAKDLIFTHAIFEGYAEDKAKIRNDMDAVRQHRETVQPIREKTGGSTFKNPEGH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SAWKLIDEAGCRGMMIGNAQMSPLHCNFMINTGQATGYELEYLGETVRQRVMDHSGVKLE
HHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEE
WEIKRVGNFMPGYEIKEFLGRATA
EEHHHHCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MKQVNGQKLLESLGNGVSAIRGRITPDAPMDRVTWFRAGGLAELMFQPHDTDDLTTFLKL
CCCCCHHHHHHHHCCCHHHHHCCCCCCCCCHHHHEEECCCCEEEEECCCCCHHHHHHHHH
VPEEVPVLVVGVGSNLLVRDGGIPGVVIRLSAKGFGDLELAGEHRIKAGAICPDKNLAAM
CCCCCCEEEEECCCCEEEECCCCCEEEEEEECCCCCCEEECCCCCEEECCCCCCCCCEEE
ALDHGIGGFYFYYGIPGSIGGALRMNAGANAGETSARVLEVHAVDRKGDRHVLSKSEMGY
EECCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCEEEEEEEEECCCCCCHHHCHHCCCC
GYRHSGAAKDLIFTHAIFEGYAEDKAKIRNDMDAVRQHRETVQPIREKTGGSTFKNPEGH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SAWKLIDEAGCRGMMIGNAQMSPLHCNFMINTGQATGYELEYLGETVRQRVMDHSGVKLE
HHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEE
WEIKRVGNFMPGYEIKEFLGRATA
EEHHHHCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]