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The map label for this gene is yhjE [H]

Identifier: 150397280

GI number: 150397280

Start: 2135064

End: 2136374

Strand: Direct

Name: yhjE [H]

Synonym: Smed_2079

Alternate gene names: 150397280

Gene position: 2135064-2136374 (Clockwise)

Preceding gene: 150397270

Following gene: 150397298

Centisome position: 56.45

GC content: 62.93

Gene sequence:

>1311_bases
ATGACAGACGCGACAACCTCGCTGTCGCCGCAGGATGGTGCGTTGCATCGACAGGCCGTGAACTCCCCGGCCCGGGTGCT
GTTCGCCAGCCTCGTCGGCACGACGATCGAATTCTTCGACTTCTATGTCTATGCGACAGCAGCGGTGATTATTTTCCCGC
ACCTTTTCTTCCCTGCAGCTGATCCGACCTCGGCAATGCTGCAGTCCTTGGCGACTTTCTCGATCGCCTTTTTCGCCCGT
CCCCTTGGCGCCGTGATCTTCGGCCACTTCGGCGACAGGATCGGCCGCAAGGCGACGCTCGTCGCCGCGCTGATGACTAT
GGGGATTTCGACGGTCGTGATCGGCCTGCTGCCCACCTACGCGACGATTGGCGTCGTGGCGCCGCTTCTCCTTGCGCTCT
GCCGCTTCGGCCAGGGCCTGGGCCTCGGCGGTGAATGGGGCGGCGCGGTGTTGCTAGCGACCGAGAATGCGCCGGAAGGC
AAGCGGAGCTGGTATGCAATGTTCCCCCAGCTCGGCGCGCCGATCGGCTTCATCCTGTCGGCCGGGACCTTCCTCGTGCT
CGGCGAGGTCATGAGCGACGAGGCCTTCCTCGCCTGGGGCTGGCGAATTCCCTTCGTCGCCAGCGTGCTGCTCGTGATCG
TCGGTCTCTATGTCCGCCTGAAGATTACCGAAACGCCGGAATTCCAGAAGGCAATCGATAAACGGGAGCGCGTCGAGGTA
CCGGTGGCGGCGATATTCCGCTCGCATAAGCGAAGCCTCGCGCTCGGCACCTTCGTGGCACTCGCGACCTTCGTCCTGTT
CTATCTGATGACCGTCTTCTCGCTCTCCTGGGGCACGACGAAGCTCGCCTATTCGCGCGAGCAGTTCCTGCTTGTACAGA
TGACCGGCGTCGTTTTTTTCGGCCTGATGATTCCCGTCTCCGGCATTCTTTCGGACCGCTTCGGACGCCGCCTGGTGCTG
GTGCTCACAACAATCGGCATCGGCATATTCGGCCTCGTCATGGCGCCGCTTCTGACATCCGGTCTCGGCGGCGCCTTCGT
CTTCTCGATCCTCGGACTCGGCCTGATGGGCCTTACCTACGGGCCGATCGGCGCGGCGCTGGCGGCTCCCTTTCCGACTG
CAGTGCGTTATACCGGCGCCTCGATGACCTTCAACCTCGCAGGCATCTTCGGCGCGTCGCTGGCACCCTACATCGCCACC
TGGCTCGCGACCAACTACAGCCTCGGCCATGTCGGCTATTATCTGATGGGCGCCGCATTGATCACGCTCGTCTGCCTGCT
GCTTTCGAACGAGGAAGAGGTCTCGGGCTGA

Upstream 100 bases:

>100_bases
TGCCCCTGTCCGGGTAAAGAATTGATCTAACCCTCTGAAACTAAGCGATTCCGCGGGGAGAATGGTTCTCTTCCCCGCGA
ATTGCTCCAGGAACGAACCA

Downstream 100 bases:

>100_bases
GGAGGAATGAACCTGAAAACAGGGCCGCGGCGGATGTCCGTCGCGGGCCCCTCTTTGGCGCTGATTCGCTTCAGGCCGTA
GCGCGGCCGAGGAATTCCTT

Product: major facilitator superfamily metabolite/H(+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTDATTSLSPQDGALHRQAVNSPARVLFASLVGTTIEFFDFYVYATAAVIIFPHLFFPAADPTSAMLQSLATFSIAFFAR
PLGAVIFGHFGDRIGRKATLVAALMTMGISTVVIGLLPTYATIGVVAPLLLALCRFGQGLGLGGEWGGAVLLATENAPEG
KRSWYAMFPQLGAPIGFILSAGTFLVLGEVMSDEAFLAWGWRIPFVASVLLVIVGLYVRLKITETPEFQKAIDKRERVEV
PVAAIFRSHKRSLALGTFVALATFVLFYLMTVFSLSWGTTKLAYSREQFLLVQMTGVVFFGLMIPVSGILSDRFGRRLVL
VLTTIGIGIFGLVMAPLLTSGLGGAFVFSILGLGLMGLTYGPIGAALAAPFPTAVRYTGASMTFNLAGIFGASLAPYIAT
WLATNYSLGHVGYYLMGAALITLVCLLLSNEEEVSG

Sequences:

>Translated_436_residues
MTDATTSLSPQDGALHRQAVNSPARVLFASLVGTTIEFFDFYVYATAAVIIFPHLFFPAADPTSAMLQSLATFSIAFFAR
PLGAVIFGHFGDRIGRKATLVAALMTMGISTVVIGLLPTYATIGVVAPLLLALCRFGQGLGLGGEWGGAVLLATENAPEG
KRSWYAMFPQLGAPIGFILSAGTFLVLGEVMSDEAFLAWGWRIPFVASVLLVIVGLYVRLKITETPEFQKAIDKRERVEV
PVAAIFRSHKRSLALGTFVALATFVLFYLMTVFSLSWGTTKLAYSREQFLLVQMTGVVFFGLMIPVSGILSDRFGRRLVL
VLTTIGIGIFGLVMAPLLTSGLGGAFVFSILGLGLMGLTYGPIGAALAAPFPTAVRYTGASMTFNLAGIFGASLAPYIAT
WLATNYSLGHVGYYLMGAALITLVCLLLSNEEEVSG
>Mature_435_residues
TDATTSLSPQDGALHRQAVNSPARVLFASLVGTTIEFFDFYVYATAAVIIFPHLFFPAADPTSAMLQSLATFSIAFFARP
LGAVIFGHFGDRIGRKATLVAALMTMGISTVVIGLLPTYATIGVVAPLLLALCRFGQGLGLGGEWGGAVLLATENAPEGK
RSWYAMFPQLGAPIGFILSAGTFLVLGEVMSDEAFLAWGWRIPFVASVLLVIVGLYVRLKITETPEFQKAIDKRERVEVP
VAAIFRSHKRSLALGTFVALATFVLFYLMTVFSLSWGTTKLAYSREQFLLVQMTGVVFFGLMIPVSGILSDRFGRRLVLV
LTTIGIGIFGLVMAPLLTSGLGGAFVFSILGLGLMGLTYGPIGAALAAPFPTAVRYTGASMTFNLAGIFGASLAPYIATW
LATNYSLGHVGYYLMGAALITLVCLLLSNEEEVSG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789941, Length=428, Percent_Identity=58.8785046728972, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1790550, Length=425, Percent_Identity=35.0588235294118, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1788292, Length=446, Percent_Identity=34.0807174887892, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1788942, Length=373, Percent_Identity=31.3672922252011, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87082404, Length=431, Percent_Identity=28.538283062645, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI87082231, Length=261, Percent_Identity=23.3716475095785, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1; PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 46437; Mature: 46306

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDATTSLSPQDGALHRQAVNSPARVLFASLVGTTIEFFDFYVYATAAVIIFPHLFFPAA
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPTSAMLQSLATFSIAFFARPLGAVIFGHFGDRIGRKATLVAALMTMGISTVVIGLLPTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
ATIGVVAPLLLALCRFGQGLGLGGEWGGAVLLATENAPEGKRSWYAMFPQLGAPIGFILS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHH
AGTFLVLGEVMSDEAFLAWGWRIPFVASVLLVIVGLYVRLKITETPEFQKAIDKRERVEV
CCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCC
PVAAIFRSHKRSLALGTFVALATFVLFYLMTVFSLSWGTTKLAYSREQFLLVQMTGVVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEHHHHHHHHHH
GLMIPVSGILSDRFGRRLVLVLTTIGIGIFGLVMAPLLTSGLGGAFVFSILGLGLMGLTY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
GPIGAALAAPFPTAVRYTGASMTFNLAGIFGASLAPYIATWLATNYSLGHVGYYLMGAAL
CCHHHHHHCCCCHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ITLVCLLLSNEEEVSG
HHHHHHHHCCCHHCCC
>Mature Secondary Structure 
TDATTSLSPQDGALHRQAVNSPARVLFASLVGTTIEFFDFYVYATAAVIIFPHLFFPAA
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPTSAMLQSLATFSIAFFARPLGAVIFGHFGDRIGRKATLVAALMTMGISTVVIGLLPTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
ATIGVVAPLLLALCRFGQGLGLGGEWGGAVLLATENAPEGKRSWYAMFPQLGAPIGFILS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHH
AGTFLVLGEVMSDEAFLAWGWRIPFVASVLLVIVGLYVRLKITETPEFQKAIDKRERVEV
CCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCC
PVAAIFRSHKRSLALGTFVALATFVLFYLMTVFSLSWGTTKLAYSREQFLLVQMTGVVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEHHHHHHHHHH
GLMIPVSGILSDRFGRRLVLVLTTIGIGIFGLVMAPLLTSGLGGAFVFSILGLGLMGLTY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
GPIGAALAAPFPTAVRYTGASMTFNLAGIFGASLAPYIATWLATNYSLGHVGYYLMGAAL
CCHHHHHHCCCCHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ITLVCLLLSNEEEVSG
HHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]