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The map label for this gene is ftsZ1 [H]

Identifier: 150397275

GI number: 150397275

Start: 2128628

End: 2130400

Strand: Reverse

Name: ftsZ1 [H]

Synonym: Smed_2074

Alternate gene names: 150397275

Gene position: 2130400-2128628 (Counterclockwise)

Preceding gene: 150397276

Following gene: 150397274

Centisome position: 56.33

GC content: 65.43

Gene sequence:

>1773_bases
ATGGCCATCAACTTGCAGAAGCCGGACATTACCGAGCTGAAGCCGCGCATCACGGTCTTCGGCGTCGGCGGCGGCGGCGG
CAACGCCGTCAACAACATGATCACCGCCGGGCTCCAGGGCGTCGATTTCGTCGTTGCCAATACGGACGCCCAGGCCCTCA
CCATGACCAAGGCCGAACGGATCATCCAGATGGGTGTCGCCGTTACCGAAGGCCTGGGTGCAGGCTCGCAGCCGGAAGTC
GGCCGTGCGGCTGCTGAAGAGTGCATCGACGAGATCATCGATCACCTGCAGGGCACGCATATGTGCTTCGTTACCGCCGG
TATGGGTGGCGGCACCGGCACCGGCGCTGCTCCGATCGTGGCCCAGGCGGCCCGCAACAAGGGTATCCTTACCGTCGGCG
TCGTCACCAAGCCCTTCCATTTCGAAGGCGGACGCCGCATGCGCATCGCCGATCAGGGCATCTCCGATCTTCAGAAGTCG
GTCGACACGCTGATCGTGATTCCGAACCAGAACCTCTTCCGCATCGCCAATGACAAGACGACCTTCGCGGACGCCTTTGC
CATGGCTGACCAGGTTCTCTATTCGGGTGTCGCCTGCATCACCGACCTCATGGTCAAGGAAGGCCTCATCAACCTCGATT
TCGCCGACGTTCGTTCGGTGATGCGCGAGATGGGCCGCGCCATGATGGGTACCGGCGAAGCTTCGGGTGAAGGCCGCGCA
ATGGCGGCGGCGGAAGCTGCGATCGCCAACCCGCTGCTCGACGAGACGTCGATGAAGGGCGCTCAAGGCCTGCTTATCTC
GATCACCGGCGGCCGCGACCTTACGCTCTTCGAAGTGGACGAGGCTGCGACGCGTATCCGCGAGGAAGTCGATCCGGACG
CCAACATCATTCTCGGTGCGACCTTCGACGAAGAACTCGAGGGCCTTATCCGGGTCTCCGTCGTCGCCACCGGCATCGAC
CGTACTGCCGCGGAGGTGGCCGGCCGCTCTGCCGACTTTCGTCAGGTAACGCAGAAGCCGATCGTCCGTCCGTCCGCCGC
TGTTCCGGCCCAGCCGCAACAGAGCATCCCGCAGCCGACCGTTTCGCATCAGCCTGCGCCCCAGCCGCAGCCGGTGCAGC
AACCGGTTCAGCAGCAGAATGTCGACCACATCGCGCTTGCGATCCGCGAAGCCGAAATGGAGCGGGAGCTCGATATAGCT
GCCCACGCCCAGATCTCCGCAGCGGCCCCGCAGCCGCAGGAAGAGGCTTTCCGTCCGCAGAGCAAGCTTTTCGCCGGCGT
CGCTCCGGCTGAAGCGCCGGCAATGCGGCCGGCGCAGCCGGCACCGCGCCCCGTCGAGATGCAGGCGCCAGTCCAGCCGC
AGATGCAGGCCCAGCCCGTCAGGCAGGAGCCCGCTCCGGTCGTACGCCAGCAGGCCGAGCCGGTCCGCATGCCTAAGGTC
GAGGATTTTCCTCCGGTCGTGAAGGCTGAAATGAACCACCGGGCACAGCCGGCGCCCTTGCATCAGGAAGAGCGCGGGCC
GATGGGGCTCCTGAACAAGATCACAACTTCCCTGGGATTGCGGGAGCGGGAGGCGACGAATGTCTCGTCCGACATGACCG
CAGCCGCACCGAGCGCCGCCTCGCAGCAGCGTCGGCCGCTTTCTCCGGAAGCCAGCCTCTATGCGCCGCGTCGCGGCCAG
CTCGACGACCACGGTCGCGCTGCCCCGCAGATGCGGTCGCATGAAGACGATCAACTCGAAATCCCGGCGTTCCTGCGCCG
CCAATCGAGCTGA

Upstream 100 bases:

>100_bases
TTCTAGATCGATCGGCATTCAGCCGGACGAGACAGGTATTCGAGTTTGAAGGAATTGGCCGGCTCGGCAAGGCGGCCAGG
GAAAGAGAAGGAACAGGACT

Downstream 100 bases:

>100_bases
TACCTACAGCGTTGTGCGTCTGATCAGCCGCACAGCGTCGCTGTAGTACTTCAGCCACTGCATGTTTTTCTTGAGCCGAT
TTCGGTTCGAGGCAAGATGC

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MAINLQKPDITELKPRITVFGVGGGGGNAVNNMITAGLQGVDFVVANTDAQALTMTKAERIIQMGVAVTEGLGAGSQPEV
GRAAAEECIDEIIDHLQGTHMCFVTAGMGGGTGTGAAPIVAQAARNKGILTVGVVTKPFHFEGGRRMRIADQGISDLQKS
VDTLIVIPNQNLFRIANDKTTFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGRAMMGTGEASGEGRA
MAAAEAAIANPLLDETSMKGAQGLLISITGGRDLTLFEVDEAATRIREEVDPDANIILGATFDEELEGLIRVSVVATGID
RTAAEVAGRSADFRQVTQKPIVRPSAAVPAQPQQSIPQPTVSHQPAPQPQPVQQPVQQQNVDHIALAIREAEMERELDIA
AHAQISAAAPQPQEEAFRPQSKLFAGVAPAEAPAMRPAQPAPRPVEMQAPVQPQMQAQPVRQEPAPVVRQQAEPVRMPKV
EDFPPVVKAEMNHRAQPAPLHQEERGPMGLLNKITTSLGLREREATNVSSDMTAAAPSAASQQRRPLSPEASLYAPRRGQ
LDDHGRAAPQMRSHEDDQLEIPAFLRRQSS

Sequences:

>Translated_590_residues
MAINLQKPDITELKPRITVFGVGGGGGNAVNNMITAGLQGVDFVVANTDAQALTMTKAERIIQMGVAVTEGLGAGSQPEV
GRAAAEECIDEIIDHLQGTHMCFVTAGMGGGTGTGAAPIVAQAARNKGILTVGVVTKPFHFEGGRRMRIADQGISDLQKS
VDTLIVIPNQNLFRIANDKTTFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGRAMMGTGEASGEGRA
MAAAEAAIANPLLDETSMKGAQGLLISITGGRDLTLFEVDEAATRIREEVDPDANIILGATFDEELEGLIRVSVVATGID
RTAAEVAGRSADFRQVTQKPIVRPSAAVPAQPQQSIPQPTVSHQPAPQPQPVQQPVQQQNVDHIALAIREAEMERELDIA
AHAQISAAAPQPQEEAFRPQSKLFAGVAPAEAPAMRPAQPAPRPVEMQAPVQPQMQAQPVRQEPAPVVRQQAEPVRMPKV
EDFPPVVKAEMNHRAQPAPLHQEERGPMGLLNKITTSLGLREREATNVSSDMTAAAPSAASQQRRPLSPEASLYAPRRGQ
LDDHGRAAPQMRSHEDDQLEIPAFLRRQSS
>Mature_589_residues
AINLQKPDITELKPRITVFGVGGGGGNAVNNMITAGLQGVDFVVANTDAQALTMTKAERIIQMGVAVTEGLGAGSQPEVG
RAAAEECIDEIIDHLQGTHMCFVTAGMGGGTGTGAAPIVAQAARNKGILTVGVVTKPFHFEGGRRMRIADQGISDLQKSV
DTLIVIPNQNLFRIANDKTTFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGRAMMGTGEASGEGRAM
AAAEAAIANPLLDETSMKGAQGLLISITGGRDLTLFEVDEAATRIREEVDPDANIILGATFDEELEGLIRVSVVATGIDR
TAAEVAGRSADFRQVTQKPIVRPSAAVPAQPQQSIPQPTVSHQPAPQPQPVQQPVQQQNVDHIALAIREAEMERELDIAA
HAQISAAAPQPQEEAFRPQSKLFAGVAPAEAPAMRPAQPAPRPVEMQAPVQPQMQAQPVRQEPAPVVRQQAEPVRMPKVE
DFPPVVKAEMNHRAQPAPLHQEERGPMGLLNKITTSLGLREREATNVSSDMTAAAPSAASQQRRPLSPEASLYAPRRGQL
DDHGRAAPQMRSHEDDQLEIPAFLRRQSS

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=292, Percent_Identity=51.027397260274, Blast_Score=262, Evalue=4e-71,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017844
- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 62921; Mature: 62790

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINLQKPDITELKPRITVFGVGGGGGNAVNNMITAGLQGVDFVVANTDAQALTMTKAER
CEECCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
IIQMGVAVTEGLGAGSQPEVGRAAAEECIDEIIDHLQGTHMCFVTAGMGGGTGTGAAPIV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHH
AQAARNKGILTVGVVTKPFHFEGGRRMRIADQGISDLQKSVDTLIVIPNQNLFRIANDKT
HHHHCCCCEEEEEEEECCEEECCCCEEEEHHCCHHHHHHCCCEEEEECCCCEEEEECCCC
TFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGRAMMGTGEASGEGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
MAAAEAAIANPLLDETSMKGAQGLLISITGGRDLTLFEVDEAATRIREEVDPDANIILGA
HHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCEEEEEECHHHHHHHHHHCCCCCCEEEEC
TFDEELEGLIRVSVVATGIDRTAAEVAGRSADFRQVTQKPIVRPSAAVPAQPQQSIPQPT
CCCHHHHHHEEEEHEECCCCHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCHHCCCCCC
VSHQPAPQPQPVQQPVQQQNVDHIALAIREAEMERELDIAAHAQISAAAPQPQEEAFRPQ
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHCCCH
SKLFAGVAPAEAPAMRPAQPAPRPVEMQAPVQPQMQAQPVRQEPAPVVRQQAEPVRMPKV
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCCCCCC
EDFPPVVKAEMNHRAQPAPLHQEERGPMGLLNKITTSLGLREREATNVSSDMTAAAPSAA
CCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCHHHCCCCHH
SQQRRPLSPEASLYAPRRGQLDDHGRAAPQMRSHEDDQLEIPAFLRRQSS
HHHCCCCCCCCCEECCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
AINLQKPDITELKPRITVFGVGGGGGNAVNNMITAGLQGVDFVVANTDAQALTMTKAER
EECCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
IIQMGVAVTEGLGAGSQPEVGRAAAEECIDEIIDHLQGTHMCFVTAGMGGGTGTGAAPIV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHH
AQAARNKGILTVGVVTKPFHFEGGRRMRIADQGISDLQKSVDTLIVIPNQNLFRIANDKT
HHHHCCCCEEEEEEEECCEEECCCCEEEEHHCCHHHHHHCCCEEEEECCCCEEEEECCCC
TFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGRAMMGTGEASGEGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
MAAAEAAIANPLLDETSMKGAQGLLISITGGRDLTLFEVDEAATRIREEVDPDANIILGA
HHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCEEEEEECHHHHHHHHHHCCCCCCEEEEC
TFDEELEGLIRVSVVATGIDRTAAEVAGRSADFRQVTQKPIVRPSAAVPAQPQQSIPQPT
CCCHHHHHHEEEEHEECCCCHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCHHCCCCCC
VSHQPAPQPQPVQQPVQQQNVDHIALAIREAEMERELDIAAHAQISAAAPQPQEEAFRPQ
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHCCCH
SKLFAGVAPAEAPAMRPAQPAPRPVEMQAPVQPQMQAQPVRQEPAPVVRQQAEPVRMPKV
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCCCCCC
EDFPPVVKAEMNHRAQPAPLHQEERGPMGLLNKITTSLGLREREATNVSSDMTAAAPSAA
CCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCHHHCCCCHH
SQQRRPLSPEASLYAPRRGQLDDHGRAAPQMRSHEDDQLEIPAFLRRQSS
HHHCCCCCCCCCEECCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1653222; 9352931; 11481430 [H]