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The map label for this gene is tsr [C]

Identifier: 150397252

GI number: 150397252

Start: 2101655

End: 2103808

Strand: Reverse

Name: tsr [C]

Synonym: Smed_2051

Alternate gene names: 150397252

Gene position: 2103808-2101655 (Counterclockwise)

Preceding gene: 150397257

Following gene: 150397251

Centisome position: 55.63

GC content: 63.32

Gene sequence:

>2154_bases
TTGATCGAGCTCCGGTTTCCCGCATCGATCGCAACGGAAGACCTGCCGTCGGCGGGGTCCAGCCACGGACTGCCATATTC
AATGAACACGCTGCCATCCGCCAAGAGTAAACTCTCCGTGAGCCAACGTCTTGCCACGCTTGCGGGCGCCGCCTTTCTCG
GGTTCGGTTCCGTTCTCGCCCTTGGCCTGTATGAACAAGGCAGCTCAGGCGAAGCACTCGAAAAGGCGATCATCGCTCAG
CGCGGTGCAGGAACGCTCGAGGAAATGCGCCTCGCCCAGGTGGAACTCGTGCTTGCGGCAATGGACACGATTGTGGACCG
CGCCGAGCGCCGGATACATCCGGACCGCGCGCTCCAGATCAGGGCCTCTCTGGCAGTTATCGAGCGCAACCAAGCCGATA
TACAGACGCTTGCGCGTCTTCTGGGGCAGTCTGAGGTCCTTGCCGGCTTCGATGCGGATCTGGCCGAACTGCGTAGGACA
GTCGAGCAGGAGTTGAAGGCTCTCGTGGAAGCGGGAGCGCCAGCCGCCGAATTTGCTCGCATCGATGATGTGATCGACGG
CGCCGGCGAGCGCCTGGGCGCGTCGCTTGCGCGATTGGCCGATGCCGCAGCCAGCCTTGCCGAGGCACGGATTGCCGATG
TGCGTGCCAGCGGCAAACATGCGCTCATGTTCCAGGCCGTCGCCTGCCTGCTGGCTATGGCAAGCCTTATCGGCCTGATC
TGGTTCCACGGGAACGCATTGCGCCGGGGCATTCTCGGTCTGCGCGATAACATGCGGCGGATACAAGAGGGCGATCTTTC
AGCTGATGTGGCCGGGCTCGAACGCGGCGACGAAATCGGTGAGATGGCACGATCGGTGGAGCTTTTCCGGGCTTCGGCAA
TCGAGAAGCGGTCGCTGGAGGAACGGGCGAAGACGAGCCGGAACGAAACTGAAGCGGAACGTGGGCGGCAGGAGGCAGAG
CGTCAGCAGGCGGCCGGCTTGATCAAAACCGCAGTTGAGACCCTTGGCCGGGCACTGAACCAGCTTGCAGACGGCAATCT
GGCTGTCGCGATCCGCGAGCCTTTCGAGGGCGGGCTCGATGCCCTGCGCCGGGACTTCAATGATACGGTGGAGCGGTTGA
GCCACGTTCTGTCGAGCGTCAGGGAAAACACCGCCTCCATCGAATCGAACGGGCGGCAAATGCGCAGTGCTGCCGACGAC
CTGGCCTGGCGGACCGAAAAGCAGGCGGCGTCGCTGGAGCAGACTTCTGCCGCGCTGGAAGAGATCACCGTCACGGTGAA
GACCGCGACCGAGCGCGCCGAAGAGGCGAGCCATATAGTCGATGAAACGCGCATAAATGCCGAGGAGTCCGGACGTATCG
TCGGTGAAGCGATCGCTGCAATGGCCCGCATCGAGGGCGCCTCCAGCGAGATCGGAAAGATCATCAACGTGATCGACGAG
ATTGCGTTCCAGACCAATCTGCTGGCGCTCAATGCCGGGGTCGAGGCCGCGCGGGCCGGAGAAGCCGGCAAAGGCTTTGC
GGTCGTTGCCCAGGAAGTGAGGGAGCTCGCCCAGCGAGCCGCCGGGGCCGCCAAAGACATCAAGGCTCTGGTGAGCCGTT
CGGGCGACGAGGTAAAGGCCGGTGTCAGGCTGGTTCAGGAGACCGGGCATGCGCTTGGCCACATCGGTACCAAGGTCGCC
CGCATCAACGAACATATGAGCTCCATCGTCCTAGCGGCGCGCGAGCAATCGACTGGCCTGAATGAAATCAACACCGCCGT
GGCGCAGCTCGACCAGATGACGCAGCAGAATGCCGCCATGGTCGAACAGACGAATGCGACGAGTCGTACGCTTGCGCAGG
ATGCCGAGATGCTAAGCGAACTCGTCGGGCAATTTCGCCATGAGCGGGCGCGCGAGACGGCGACCGGCATGGCGGCGGTC
CAACCGTCGGGCAGGGGAGGCACGACCATGGCGAGCGTCCAGGCGAGCGCGACACCGGGGGCTGGCGCGACGACCCTCAC
GCTCCGCAAGTCAGGCACAGCCGCACAATCATCCACGCGCTCCGTTCCATCTCCCGCCAAGGCGTTGATGGGAAAATTGG
CGGGCGCATTTGGCAACAGCCCGGGTTCGCTGCCGTCGGCAAAGGCATCCGGTAAAAATTGGGAAGAGTTTTGA

Upstream 100 bases:

>100_bases
AGCATTGATCTCGTGTTTTAGCAATTGTTTAAGATGTATTTGCCAATGTCCAATGACGCGGAGAAGTGCACCACTTCGAT
ATGACATGAGGTCATCCGGT

Downstream 100 bases:

>100_bases
TCATGAGCAACGCAATCAAACAGTCAGGCGCCTACCTTGAAATCGTCTCCTTTCATCTGGGCGACCAGGAATTCTGCATA
GACATCATGGCGATCCGAGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 717; Mature: 717

Protein sequence:

>717_residues
MIELRFPASIATEDLPSAGSSHGLPYSMNTLPSAKSKLSVSQRLATLAGAAFLGFGSVLALGLYEQGSSGEALEKAIIAQ
RGAGTLEEMRLAQVELVLAAMDTIVDRAERRIHPDRALQIRASLAVIERNQADIQTLARLLGQSEVLAGFDADLAELRRT
VEQELKALVEAGAPAAEFARIDDVIDGAGERLGASLARLADAAASLAEARIADVRASGKHALMFQAVACLLAMASLIGLI
WFHGNALRRGILGLRDNMRRIQEGDLSADVAGLERGDEIGEMARSVELFRASAIEKRSLEERAKTSRNETEAERGRQEAE
RQQAAGLIKTAVETLGRALNQLADGNLAVAIREPFEGGLDALRRDFNDTVERLSHVLSSVRENTASIESNGRQMRSAADD
LAWRTEKQAASLEQTSAALEEITVTVKTATERAEEASHIVDETRINAEESGRIVGEAIAAMARIEGASSEIGKIINVIDE
IAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRAAGAAKDIKALVSRSGDEVKAGVRLVQETGHALGHIGTKVA
RINEHMSSIVLAAREQSTGLNEINTAVAQLDQMTQQNAAMVEQTNATSRTLAQDAEMLSELVGQFRHERARETATGMAAV
QPSGRGGTTMASVQASATPGAGATTLTLRKSGTAAQSSTRSVPSPAKALMGKLAGAFGNSPGSLPSAKASGKNWEEF

Sequences:

>Translated_717_residues
MIELRFPASIATEDLPSAGSSHGLPYSMNTLPSAKSKLSVSQRLATLAGAAFLGFGSVLALGLYEQGSSGEALEKAIIAQ
RGAGTLEEMRLAQVELVLAAMDTIVDRAERRIHPDRALQIRASLAVIERNQADIQTLARLLGQSEVLAGFDADLAELRRT
VEQELKALVEAGAPAAEFARIDDVIDGAGERLGASLARLADAAASLAEARIADVRASGKHALMFQAVACLLAMASLIGLI
WFHGNALRRGILGLRDNMRRIQEGDLSADVAGLERGDEIGEMARSVELFRASAIEKRSLEERAKTSRNETEAERGRQEAE
RQQAAGLIKTAVETLGRALNQLADGNLAVAIREPFEGGLDALRRDFNDTVERLSHVLSSVRENTASIESNGRQMRSAADD
LAWRTEKQAASLEQTSAALEEITVTVKTATERAEEASHIVDETRINAEESGRIVGEAIAAMARIEGASSEIGKIINVIDE
IAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRAAGAAKDIKALVSRSGDEVKAGVRLVQETGHALGHIGTKVA
RINEHMSSIVLAAREQSTGLNEINTAVAQLDQMTQQNAAMVEQTNATSRTLAQDAEMLSELVGQFRHERARETATGMAAV
QPSGRGGTTMASVQASATPGAGATTLTLRKSGTAAQSSTRSVPSPAKALMGKLAGAFGNSPGSLPSAKASGKNWEEF
>Mature_717_residues
MIELRFPASIATEDLPSAGSSHGLPYSMNTLPSAKSKLSVSQRLATLAGAAFLGFGSVLALGLYEQGSSGEALEKAIIAQ
RGAGTLEEMRLAQVELVLAAMDTIVDRAERRIHPDRALQIRASLAVIERNQADIQTLARLLGQSEVLAGFDADLAELRRT
VEQELKALVEAGAPAAEFARIDDVIDGAGERLGASLARLADAAASLAEARIADVRASGKHALMFQAVACLLAMASLIGLI
WFHGNALRRGILGLRDNMRRIQEGDLSADVAGLERGDEIGEMARSVELFRASAIEKRSLEERAKTSRNETEAERGRQEAE
RQQAAGLIKTAVETLGRALNQLADGNLAVAIREPFEGGLDALRRDFNDTVERLSHVLSSVRENTASIESNGRQMRSAADD
LAWRTEKQAASLEQTSAALEEITVTVKTATERAEEASHIVDETRINAEESGRIVGEAIAAMARIEGASSEIGKIINVIDE
IAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRAAGAAKDIKALVSRSGDEVKAGVRLVQETGHALGHIGTKVA
RINEHMSSIVLAAREQSTGLNEINTAVAQLDQMTQQNAAMVEQTNATSRTLAQDAEMLSELVGQFRHERARETATGMAAV
QPSGRGGTTMASVQASATPGAGATTLTLRKSGTAAQSSTRSVPSPAKALMGKLAGAFGNSPGSLPSAKASGKNWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=272, Percent_Identity=44.1176470588235, Blast_Score=189, Evalue=8e-49,
Organism=Escherichia coli, GI1788194, Length=309, Percent_Identity=39.8058252427184, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=40, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1787690, Length=304, Percent_Identity=37.5, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1789453, Length=247, Percent_Identity=34.8178137651822, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 75736; Mature: 75736

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELRFPASIATEDLPSAGSSHGLPYSMNTLPSAKSKLSVSQRLATLAGAAFLGFGSVLA
CEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYEQGSSGEALEKAIIAQRGAGTLEEMRLAQVELVLAAMDTIVDRAERRIHPDRALQI
HHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RASLAVIERNQADIQTLARLLGQSEVLAGFDADLAELRRTVEQELKALVEAGAPAAEFAR
HHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IDDVIDGAGERLGASLARLADAAASLAEARIADVRASGKHALMFQAVACLLAMASLIGLI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WFHGNALRRGILGLRDNMRRIQEGDLSADVAGLERGDEIGEMARSVELFRASAIEKRSLE
HHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ERAKTSRNETEAERGRQEAERQQAAGLIKTAVETLGRALNQLADGNLAVAIREPFEGGLD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHH
ALRRDFNDTVERLSHVLSSVRENTASIESNGRQMRSAADDLAWRTEKQAASLEQTSAALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EITVTVKTATERAEEASHIVDETRINAEESGRIVGEAIAAMARIEGASSEIGKIINVIDE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRAAGAAKDIKALVSRSGDEVKA
HHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHH
GVRLVQETGHALGHIGTKVARINEHMSSIVLAAREQSTGLNEINTAVAQLDQMTQQNAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VEQTNATSRTLAQDAEMLSELVGQFRHERARETATGMAAVQPSGRGGTTMASVQASATPG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCCC
AGATTLTLRKSGTAAQSSTRSVPSPAKALMGKLAGAFGNSPGSLPSAKASGKNWEEF
CCCEEEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIELRFPASIATEDLPSAGSSHGLPYSMNTLPSAKSKLSVSQRLATLAGAAFLGFGSVLA
CEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYEQGSSGEALEKAIIAQRGAGTLEEMRLAQVELVLAAMDTIVDRAERRIHPDRALQI
HHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RASLAVIERNQADIQTLARLLGQSEVLAGFDADLAELRRTVEQELKALVEAGAPAAEFAR
HHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IDDVIDGAGERLGASLARLADAAASLAEARIADVRASGKHALMFQAVACLLAMASLIGLI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WFHGNALRRGILGLRDNMRRIQEGDLSADVAGLERGDEIGEMARSVELFRASAIEKRSLE
HHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ERAKTSRNETEAERGRQEAERQQAAGLIKTAVETLGRALNQLADGNLAVAIREPFEGGLD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHH
ALRRDFNDTVERLSHVLSSVRENTASIESNGRQMRSAADDLAWRTEKQAASLEQTSAALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EITVTVKTATERAEEASHIVDETRINAEESGRIVGEAIAAMARIEGASSEIGKIINVIDE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRAAGAAKDIKALVSRSGDEVKA
HHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHH
GVRLVQETGHALGHIGTKVARINEHMSSIVLAAREQSTGLNEINTAVAQLDQMTQQNAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VEQTNATSRTLAQDAEMLSELVGQFRHERARETATGMAAVQPSGRGGTTMASVQASATPG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCCC
AGATTLTLRKSGTAAQSSTRSVPSPAKALMGKLAGAFGNSPGSLPSAKASGKNWEEF
CCCEEEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]