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The map label for this gene is serB [C]

Identifier: 150397213

GI number: 150397213

Start: 2063005

End: 2063892

Strand: Direct

Name: serB [C]

Synonym: Smed_2012

Alternate gene names: 150397213

Gene position: 2063005-2063892 (Clockwise)

Preceding gene: 150397211

Following gene: 150397214

Centisome position: 54.55

GC content: 62.5

Gene sequence:

>888_bases
ATGGCTCTCGTTGCCACGCTTATCGCCAATCCGTCAAATCCGGTTCTGACGCCAGCACGCGCGGAGGCGGCAGCGGAACG
CCTCGATGCATCAGGACTCTATTGGCTCGCGGACGGCATCGCCTGCGACATCGTGTTGAGGGATGGCACCGATGCCGGCG
AAGCACAAGCCGGGCTACGTGAGACGGTTGCCGGCGCCGCTATCGATGTCGCTGTGCAGGAGGCCGAAAGCCGTCGGAAG
CGATTTCTGATCGCCGACATGGATTCGACCATGATCGGGCAGGAATGCATCGATGAACTGGCCGCGGAGGTCGGCTTGAA
GGAGAAGGTCGCAGCAATCACGTCGCGGGCCATGAACGGTGAGATCGCGTTCGAACCGGCACTCGTCGAAAGAGTGGCAC
TTCTCAAGGGCCTGCCTGTTTCGGTCGTCGAGGAGGTCATTGCCAAGCGTATCACATTGACGCCCGGCGGCCGCGAACTC
ATTGCCACGATGAAGGCCAAGGGCCACTATACGGCGCTCGTCTCGGGTGGCTTCACCGTGTTCACCGGACCGATAGCGGA
AATGCTCGGCTTCGACGAAAGCCGCGCCAATATTCTCCGTGACGAGGATGGCAGGCTCACCGGCGATGTCGCTCGGCCGA
TTCTGGGCAAGCAGGCAAAGATCGACGCGCTTATCGATATTTCGGAACGGCTCGGCATCACGCCAGCGGACGCCATCGCC
GTCGGCGACGGCGCCAACGATCTCGGCATGCTGCAACTTGCCGGCACCGGAGTGGCGCTACACGCCAAGCCCGTGGTTGC
CGAGCAGGCGAGGATCCGCATCGATCACGGCGACCTCACCGCCCTGCTCTACCTTCAGGGTTACCGGAAGACGGACTTCG
TGGCGTGA

Upstream 100 bases:

>100_bases
CCCGTGTCTCTGCGCAAGCTTCACCCCCAGCGCAGACTTGCCGCTGGCGGTTGGTCCGGTTATCAGGATCGCGTCGATGT
CTCTCGCAAGGTTTTGCATC

Downstream 100 bases:

>100_bases
TCATCCACGAGACCGAGCGGCTCAGACTCCGTGCCTGGCTGGAGGCCGATCGCGATCTCTTTGCCGAGATCAACAGCGAT
CCAAAGGTGATGGAGTTTTT

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MALVATLIANPSNPVLTPARAEAAAERLDASGLYWLADGIACDIVLRDGTDAGEAQAGLRETVAGAAIDVAVQEAESRRK
RFLIADMDSTMIGQECIDELAAEVGLKEKVAAITSRAMNGEIAFEPALVERVALLKGLPVSVVEEVIAKRITLTPGGREL
IATMKAKGHYTALVSGGFTVFTGPIAEMLGFDESRANILRDEDGRLTGDVARPILGKQAKIDALIDISERLGITPADAIA
VGDGANDLGMLQLAGTGVALHAKPVVAEQARIRIDHGDLTALLYLQGYRKTDFVA

Sequences:

>Translated_295_residues
MALVATLIANPSNPVLTPARAEAAAERLDASGLYWLADGIACDIVLRDGTDAGEAQAGLRETVAGAAIDVAVQEAESRRK
RFLIADMDSTMIGQECIDELAAEVGLKEKVAAITSRAMNGEIAFEPALVERVALLKGLPVSVVEEVIAKRITLTPGGREL
IATMKAKGHYTALVSGGFTVFTGPIAEMLGFDESRANILRDEDGRLTGDVARPILGKQAKIDALIDISERLGITPADAIA
VGDGANDLGMLQLAGTGVALHAKPVVAEQARIRIDHGDLTALLYLQGYRKTDFVA
>Mature_294_residues
ALVATLIANPSNPVLTPARAEAAAERLDASGLYWLADGIACDIVLRDGTDAGEAQAGLRETVAGAAIDVAVQEAESRRKR
FLIADMDSTMIGQECIDELAAEVGLKEKVAAITSRAMNGEIAFEPALVERVALLKGLPVSVVEEVIAKRITLTPGGRELI
ATMKAKGHYTALVSGGFTVFTGPIAEMLGFDESRANILRDEDGRLTGDVARPILGKQAKIDALIDISERLGITPADAIAV
GDGANDLGMLQLAGTGVALHAKPVVAEQARIRIDHGDLTALLYLQGYRKTDFVA

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=179, Percent_Identity=32.9608938547486, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1790849, Length=206, Percent_Identity=40.7766990291262, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI115534456, Length=174, Percent_Identity=38.5057471264368, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115534454, Length=174, Percent_Identity=38.5057471264368, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115534458, Length=176, Percent_Identity=38.0681818181818, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321647, Length=220, Percent_Identity=39.0909090909091, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24661601, Length=246, Percent_Identity=29.2682926829268, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31024; Mature: 30893

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVATLIANPSNPVLTPARAEAAAERLDASGLYWLADGIACDIVLRDGTDAGEAQAGLR
CCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCEEEEEEEECCCCCCHHHHHHH
ETVAGAAIDVAVQEAESRRKRFLIADMDSTMIGQECIDELAAEVGLKEKVAAITSRAMNG
HHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
EIAFEPALVERVALLKGLPVSVVEEVIAKRITLTPGGRELIATMKAKGHYTALVSGGFTV
CEEECHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCCHHHHHHHHCCCCEEEEEECCEEE
FTGPIAEMLGFDESRANILRDEDGRLTGDVARPILGKQAKIDALIDISERLGITPADAIA
EECHHHHHHCCCCHHHHHCCCCCCCEEHHHHHHHCCCCCCHHHEEEHHHHCCCCCCCEEE
VGDGANDLGMLQLAGTGVALHAKPVVAEQARIRIDHGDLTALLYLQGYRKTDFVA
ECCCCCCCEEEEEECCCEEEECCCCEECCEEEEEECCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
ALVATLIANPSNPVLTPARAEAAAERLDASGLYWLADGIACDIVLRDGTDAGEAQAGLR
CEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCEEEEEEEECCCCCCHHHHHHH
ETVAGAAIDVAVQEAESRRKRFLIADMDSTMIGQECIDELAAEVGLKEKVAAITSRAMNG
HHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
EIAFEPALVERVALLKGLPVSVVEEVIAKRITLTPGGRELIATMKAKGHYTALVSGGFTV
CEEECHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCCHHHHHHHHCCCCEEEEEECCEEE
FTGPIAEMLGFDESRANILRDEDGRLTGDVARPILGKQAKIDALIDISERLGITPADAIA
EECHHHHHHCCCCHHHHHCCCCCCCEEHHHHHHHCCCCCCHHHEEEHHHHCCCCCCCEEE
VGDGANDLGMLQLAGTGVALHAKPVVAEQARIRIDHGDLTALLYLQGYRKTDFVA
ECCCCCCCEEEEEECCCEEEECCCCEECCEEEEEECCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]