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The map label for this gene is ydcR [C]

Identifier: 150397176

GI number: 150397176

Start: 2024258

End: 2025802

Strand: Reverse

Name: ydcR [C]

Synonym: Smed_1974

Alternate gene names: 150397176

Gene position: 2025802-2024258 (Counterclockwise)

Preceding gene: 150397178

Following gene: 150397175

Centisome position: 53.57

GC content: 66.28

Gene sequence:

>1545_bases
ATGCCCTTCCCCGCGGACCGGGCCGGCGCGCGTGCCTTTACGGGGCGAATACCGAGGCGACCGCTCTTGCGCCGGCTGCA
GCCTCCATGCAACATCCATACATTGAACAATCGCAAGGTTTCGATGAACGAGGATCGCGTTGAGGTTTCCTGGGTGCCGG
CGCTCGGCAGAGCGAAGGGGCCTCTTTATCTTGCCATTGCAGACGAGATCGCCGCCGACATCGCCGCAGGCCGGCTGGCA
AACGGCATGCGCCTGCCGCCGCAACGGGTTCTGGCGGCGGCGCTCGGTATCGACTTTACCACCGTCAGCCGCGCCTACAA
CGAAGCGCGTCGGCGCGGCTTGGTCGAGGGCCGCGTGGGGCAGGGTACCTATGTCAGGACCCGTGAGAGGAGTTCGGGCC
GTCCGTCAGCGGATCGCCTCGCGGCTGGTCTTGTCGACATGAGCATGAATCTGCCGCCGCTCTTCGACGACCCGGCTCTG
TCGGCGAAAATGTGGGCGGATGTCGGGGCACTCGGTCATGGCGGGCTTGACCAGCGGAGCCCTGAACTGTTGATGCGCTA
TCAGCCCGTCGGCGGCACGGAGCGGGACAGGTCTGCAGGGGCGGCCTGGCTCAAGCCGCGGCTCGGTGGACTTCAGGCCG
ATCGGATGGTCGTCTGCACGGGCGCGCAAGGAGCATTGCTTGCGAGCGTCGGCATGCTGGCGACGAAGGGTGACAGGGTC
TGCGCCGAAGCGCTGGCCTATCCGGGCCTCCGTTCGCTGGCCGCCTATCTGGGCATCGAACTCGTCAGTGTTGGGATCGA
CCGCAACGGGATCTTGCCCGAAGCCTTCGAGGAGGCGTGCGTCCTCCATAGGCCGAAGGCTCTCTATTGTAATCCCACGC
TTCACAATCCGACGACCGCCACGCTCCCGCTCGATCGCCGCGAAGCTATCGTGGAGATCGCACGCCGCCACGGCGTAGCC
ATTATCGAGGACGACGCCTACGGGGCCTTGCCCGCAAGTCCCGTTCCGCCATTGGCCGCGCTCGCGCCTGACCTCGTCTA
TCATGTCGCAGGTCTTGCCAAGTGCCTCTCGCCGGCGCTTCGCATCGCCTATCTGGTCGCGCCTGACCGATCGGCGGCCA
TCCGCCTGGAAGGCGCGGTTCGGGCGACGGCCGGGATGACGTCGCCTCTTTCGGTCGCCATCGCAACGCGTTGGCTGGAG
GAAGGAACGGCGCAGGCGGTCCTGGACGCAATCCGCACCGAGGCCGGCGCACGCCAGCAGATCGCGAGCAGGAGCCTCGA
GGGCGCGGACCTTTCGAGCGATCGCGAGGGCTTCCATCTCTGGCTGAAGCTTCCTTCCGGCTGGAATCGCGGTGAGTTTA
CCGCACAGTTGCGAGCGGCCGGGATCGGCGTCGTCGCAAGCGATGCCTTTGCGATATCGGATCCACCCGAAGCTGTGCGG
CTCGGTCTCGGCGCCGCCCGAACGCGCGATGACCTGCGGGAGAGTCTTGACGTCATCGCCGGCCTTCTTGCCCGCTCGCC
GGCTGCACACAATCTCATTGTCTGA

Upstream 100 bases:

>100_bases
GTTCGCCTTACAATTTAGCTGAATGCTTGATTTTCTGGGCTTCAAATACGGTGCAGAGATTATCGTCTTCACAACGCTTC
CACCATATGCCCTTGGATAT

Downstream 100 bases:

>100_bases
ATTCGTTGCAGTCGCGCCTGACGTGGTGCGTGAATGCCCTTGTTGCGCGAATTTGCCGCGGCGCAATATGCATACAATCC
GTTGTTTCTGTATGGTTTGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MPFPADRAGARAFTGRIPRRPLLRRLQPPCNIHTLNNRKVSMNEDRVEVSWVPALGRAKGPLYLAIADEIAADIAAGRLA
NGMRLPPQRVLAAALGIDFTTVSRAYNEARRRGLVEGRVGQGTYVRTRERSSGRPSADRLAAGLVDMSMNLPPLFDDPAL
SAKMWADVGALGHGGLDQRSPELLMRYQPVGGTERDRSAGAAWLKPRLGGLQADRMVVCTGAQGALLASVGMLATKGDRV
CAEALAYPGLRSLAAYLGIELVSVGIDRNGILPEAFEEACVLHRPKALYCNPTLHNPTTATLPLDRREAIVEIARRHGVA
IIEDDAYGALPASPVPPLAALAPDLVYHVAGLAKCLSPALRIAYLVAPDRSAAIRLEGAVRATAGMTSPLSVAIATRWLE
EGTAQAVLDAIRTEAGARQQIASRSLEGADLSSDREGFHLWLKLPSGWNRGEFTAQLRAAGIGVVASDAFAISDPPEAVR
LGLGAARTRDDLRESLDVIAGLLARSPAAHNLIV

Sequences:

>Translated_514_residues
MPFPADRAGARAFTGRIPRRPLLRRLQPPCNIHTLNNRKVSMNEDRVEVSWVPALGRAKGPLYLAIADEIAADIAAGRLA
NGMRLPPQRVLAAALGIDFTTVSRAYNEARRRGLVEGRVGQGTYVRTRERSSGRPSADRLAAGLVDMSMNLPPLFDDPAL
SAKMWADVGALGHGGLDQRSPELLMRYQPVGGTERDRSAGAAWLKPRLGGLQADRMVVCTGAQGALLASVGMLATKGDRV
CAEALAYPGLRSLAAYLGIELVSVGIDRNGILPEAFEEACVLHRPKALYCNPTLHNPTTATLPLDRREAIVEIARRHGVA
IIEDDAYGALPASPVPPLAALAPDLVYHVAGLAKCLSPALRIAYLVAPDRSAAIRLEGAVRATAGMTSPLSVAIATRWLE
EGTAQAVLDAIRTEAGARQQIASRSLEGADLSSDREGFHLWLKLPSGWNRGEFTAQLRAAGIGVVASDAFAISDPPEAVR
LGLGAARTRDDLRESLDVIAGLLARSPAAHNLIV
>Mature_513_residues
PFPADRAGARAFTGRIPRRPLLRRLQPPCNIHTLNNRKVSMNEDRVEVSWVPALGRAKGPLYLAIADEIAADIAAGRLAN
GMRLPPQRVLAAALGIDFTTVSRAYNEARRRGLVEGRVGQGTYVRTRERSSGRPSADRLAAGLVDMSMNLPPLFDDPALS
AKMWADVGALGHGGLDQRSPELLMRYQPVGGTERDRSAGAAWLKPRLGGLQADRMVVCTGAQGALLASVGMLATKGDRVC
AEALAYPGLRSLAAYLGIELVSVGIDRNGILPEAFEEACVLHRPKALYCNPTLHNPTTATLPLDRREAIVEIARRHGVAI
IEDDAYGALPASPVPPLAALAPDLVYHVAGLAKCLSPALRIAYLVAPDRSAAIRLEGAVRATAGMTSPLSVAIATRWLEE
GTAQAVLDAIRTEAGARQQIASRSLEGADLSSDREGFHLWLKLPSGWNRGEFTAQLRAAGIGVVASDAFAISDPPEAVRL
GLGAARTRDDLRESLDVIAGLLARSPAAHNLIV

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=319, Percent_Identity=26.6457680250784, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI33469970, Length=319, Percent_Identity=26.6457680250784, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1787710, Length=449, Percent_Identity=25.3897550111359, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790797, Length=448, Percent_Identity=23.4375, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321000, Length=206, Percent_Identity=26.2135922330097, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54692; Mature: 54560

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFPADRAGARAFTGRIPRRPLLRRLQPPCNIHTLNNRKVSMNEDRVEVSWVPALGRAKG
CCCCCCCCCCHHHHCCCCCCHHHHHCCCCCCEEECCCCEEECCCCEEEEEEECCCCCCCC
PLYLAIADEIAADIAAGRLANGMRLPPQRVLAAALGIDFTTVSRAYNEARRRGLVEGRVG
CEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
QGTYVRTRERSSGRPSADRLAAGLVDMSMNLPPLFDDPALSAKMWADVGALGHGGLDQRS
CCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
PELLMRYQPVGGTERDRSAGAAWLKPRLGGLQADRMVVCTGAQGALLASVGMLATKGDRV
HHHEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCHH
CAEALAYPGLRSLAAYLGIELVSVGIDRNGILPEAFEEACVLHRPKALYCNPTLHNPTTA
HHHHHHCCCHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEE
TLPLDRREAIVEIARRHGVAIIEDDAYGALPASPVPPLAALAPDLVYHVAGLAKCLSPAL
ECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RIAYLVAPDRSAAIRLEGAVRATAGMTSPLSVAIATRWLEEGTAQAVLDAIRTEAGARQQ
EEEEEECCCCCCEEEECCCEEHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
IASRSLEGADLSSDREGFHLWLKLPSGWNRGEFTAQLRAAGIGVVASDAFAISDPPEAVR
HHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHCCCEEEECCCEECCCCHHHHH
LGLGAARTRDDLRESLDVIAGLLARSPAAHNLIV
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PFPADRAGARAFTGRIPRRPLLRRLQPPCNIHTLNNRKVSMNEDRVEVSWVPALGRAKG
CCCCCCCCCHHHHCCCCCCHHHHHCCCCCCEEECCCCEEECCCCEEEEEEECCCCCCCC
PLYLAIADEIAADIAAGRLANGMRLPPQRVLAAALGIDFTTVSRAYNEARRRGLVEGRVG
CEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
QGTYVRTRERSSGRPSADRLAAGLVDMSMNLPPLFDDPALSAKMWADVGALGHGGLDQRS
CCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
PELLMRYQPVGGTERDRSAGAAWLKPRLGGLQADRMVVCTGAQGALLASVGMLATKGDRV
HHHEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCHH
CAEALAYPGLRSLAAYLGIELVSVGIDRNGILPEAFEEACVLHRPKALYCNPTLHNPTTA
HHHHHHCCCHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEE
TLPLDRREAIVEIARRHGVAIIEDDAYGALPASPVPPLAALAPDLVYHVAGLAKCLSPAL
ECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RIAYLVAPDRSAAIRLEGAVRATAGMTSPLSVAIATRWLEEGTAQAVLDAIRTEAGARQQ
EEEEEECCCCCCEEEECCCEEHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
IASRSLEGADLSSDREGFHLWLKLPSGWNRGEFTAQLRAAGIGVVASDAFAISDPPEAVR
HHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHCCCEEEECCCEECCCCHHHHH
LGLGAARTRDDLRESLDVIAGLLARSPAAHNLIV
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1400197 [H]