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The map label for this gene is dgdR [H]

Identifier: 150396991

GI number: 150396991

Start: 1871206

End: 1872102

Strand: Reverse

Name: dgdR [H]

Synonym: Smed_1788

Alternate gene names: 150396991

Gene position: 1872102-1871206 (Counterclockwise)

Preceding gene: 150396993

Following gene: 150396983

Centisome position: 49.5

GC content: 61.76

Gene sequence:

>897_bases
ATGAACATGATGATGCGCCATGCTCTTCCGCTGCTCGAAATGGATGTGCTCAAGACCTTCGTCGCCATTGCCGAGACCGG
CAACTTCACGACTGCGGCGGAGACGGTCTACCGCACGCCCTCAGCTGTTTCCATGCAGATCAAGAAGCTCGAGGAAATGC
TCGGCTGCACGTTGTTCCTGCGCGACGCCCGATCTGTCTCGCTTACTCCGAAGGGCGAACTCCTGCTCGGTTATGCCCGG
CGGCTCCTGTCGCTGAACAATGAGACGGTGTCCCGCTTCCTGCTGCCCGACATGAACGGTGTTGTGCGGGTCGGTGCGCC
GGAGGATGTCGGCGAACGAATCCTGCCGGCCGTGTTGAAGCGCTTTGCCGAGACTTATCCGAACGTCACCATCGACGTTT
CGATCGGCATGAGCAATGCTATGCGCAAGCGGGTTGACGAGCATCGGTTGGATATCGCGGTGTACAACAGCCTATCGGAC
GAATCTTCGAAGGACGGCGAGATTCTGATGCAGGAGAAACTGGTCTGGGCCGGTGCGAAATGCGGAAACGCACATCTGCG
CGATCCTCTGCCGGTTTCCATGTGGGAGGACGGCTGCGTCTGGCGCGCCGATGCGGTCGAGAAGCTGTCGCGCGCCGGCC
GGAAGTTCCGCGTCGCATTTTTGAGTGCCTATACGACCGGACAGCGCGCCGCTGTCCTCGCCGGGCTCGCGATCGCACCG
CTGCCGCGCTATCTCGTGCAGGGCGAAATGGTTCAACTCGGCGAGCGTGACGGCCTGCCGGATCTCGGTCACTACGACAT
TGGCCTCAAGGTCATCGAGGATGCGCCGGCGCCGGTTCTGGCGGTTGCGGAGCATGTTCGCGCCGCATTCGCCGAGCTGC
AGATGCAGGCGGCATAG

Upstream 100 bases:

>100_bases
TTTTCCCGTCGTTGCAGCTTGACTATCGCGCATGGCTGATGTTCAATCAAACGAAATGGAAGAATGTTATCATTCAGTTT
TTCTGATCTAGGATGCCGCC

Downstream 100 bases:

>100_bases
CGGCGGGCGGAACATGCCGGGAATGAACATTTAATCCGGCTGCGAACCCCTTGCGGTCGCGGCCAGTCGCTGGAATGCCG
TCGGCGTGGTCAGCCCGGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNMMMRHALPLLEMDVLKTFVAIAETGNFTTAAETVYRTPSAVSMQIKKLEEMLGCTLFLRDARSVSLTPKGELLLGYAR
RLLSLNNETVSRFLLPDMNGVVRVGAPEDVGERILPAVLKRFAETYPNVTIDVSIGMSNAMRKRVDEHRLDIAVYNSLSD
ESSKDGEILMQEKLVWAGAKCGNAHLRDPLPVSMWEDGCVWRADAVEKLSRAGRKFRVAFLSAYTTGQRAAVLAGLAIAP
LPRYLVQGEMVQLGERDGLPDLGHYDIGLKVIEDAPAPVLAVAEHVRAAFAELQMQAA

Sequences:

>Translated_298_residues
MNMMMRHALPLLEMDVLKTFVAIAETGNFTTAAETVYRTPSAVSMQIKKLEEMLGCTLFLRDARSVSLTPKGELLLGYAR
RLLSLNNETVSRFLLPDMNGVVRVGAPEDVGERILPAVLKRFAETYPNVTIDVSIGMSNAMRKRVDEHRLDIAVYNSLSD
ESSKDGEILMQEKLVWAGAKCGNAHLRDPLPVSMWEDGCVWRADAVEKLSRAGRKFRVAFLSAYTTGQRAAVLAGLAIAP
LPRYLVQGEMVQLGERDGLPDLGHYDIGLKVIEDAPAPVLAVAEHVRAAFAELQMQAA
>Mature_298_residues
MNMMMRHALPLLEMDVLKTFVAIAETGNFTTAAETVYRTPSAVSMQIKKLEEMLGCTLFLRDARSVSLTPKGELLLGYAR
RLLSLNNETVSRFLLPDMNGVVRVGAPEDVGERILPAVLKRFAETYPNVTIDVSIGMSNAMRKRVDEHRLDIAVYNSLSD
ESSKDGEILMQEKLVWAGAKCGNAHLRDPLPVSMWEDGCVWRADAVEKLSRAGRKFRVAFLSAYTTGQRAAVLAGLAIAP
LPRYLVQGEMVQLGERDGLPDLGHYDIGLKVIEDAPAPVLAVAEHVRAAFAELQMQAA

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=258, Percent_Identity=31.3953488372093, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787806, Length=164, Percent_Identity=30.4878048780488, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48994962, Length=146, Percent_Identity=30.1369863013699, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI145693105, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788481, Length=242, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786713, Length=74, Percent_Identity=48.6486486486487, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790399, Length=262, Percent_Identity=27.4809160305344, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=133, Percent_Identity=34.5864661654135, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788706, Length=163, Percent_Identity=26.9938650306748, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786401, Length=152, Percent_Identity=34.2105263157895, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=148, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081904, Length=128, Percent_Identity=38.28125, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=30.5785123966942, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788297, Length=171, Percent_Identity=28.0701754385965, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32784; Mature: 32784

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMMMRHALPLLEMDVLKTFVAIAETGNFTTAAETVYRTPSAVSMQIKKLEEMLGCTLFL
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHEE
RDARSVSLTPKGELLLGYARRLLSLNNETVSRFLLPDMNGVVRVGAPEDVGERILPAVLK
ECCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
RFAETYPNVTIDVSIGMSNAMRKRVDEHRLDIAVYNSLSDESSKDGEILMQEKLVWAGAK
HHHHHCCCEEEEEECCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHHCCCC
CGNAHLRDPLPVSMWEDGCVWRADAVEKLSRAGRKFRVAFLSAYTTGQRAAVLAGLAIAP
CCCCCCCCCCCCCCCCCCCEECHHHHHHHHHCCCEEEEEEEEHHCCCCHHHHHHHHHHHH
LPRYLVQGEMVQLGERDGLPDLGHYDIGLKVIEDAPAPVLAVAEHVRAAFAELQMQAA
HHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNMMMRHALPLLEMDVLKTFVAIAETGNFTTAAETVYRTPSAVSMQIKKLEEMLGCTLFL
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHEE
RDARSVSLTPKGELLLGYARRLLSLNNETVSRFLLPDMNGVVRVGAPEDVGERILPAVLK
ECCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
RFAETYPNVTIDVSIGMSNAMRKRVDEHRLDIAVYNSLSDESSKDGEILMQEKLVWAGAK
HHHHHCCCEEEEEECCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHHCCCC
CGNAHLRDPLPVSMWEDGCVWRADAVEKLSRAGRKFRVAFLSAYTTGQRAAVLAGLAIAP
CCCCCCCCCCCCCCCCCCCEECHHHHHHHHHCCCEEEEEEEEHHCCCCHHHHHHHHHHHH
LPRYLVQGEMVQLGERDGLPDLGHYDIGLKVIEDAPAPVLAVAEHVRAAFAELQMQAA
HHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]