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The map label for this gene is cobO [H]

Identifier: 150396961

GI number: 150396961

Start: 1837623

End: 1838267

Strand: Reverse

Name: cobO [H]

Synonym: Smed_1758

Alternate gene names: 150396961

Gene position: 1838267-1837623 (Counterclockwise)

Preceding gene: 150396962

Following gene: 150396960

Centisome position: 48.61

GC content: 58.29

Gene sequence:

>645_bases
ATGAGCGAGGAAATCGCGAATACCGGCGAACCGACTGCCGAAAAGGACGAAGCGCGTCATGCCTTGAAGATGGCGAAGAA
GAAGACCGCCCGTGACAAGATCATGGCCACGAAGACGGACGAAAAAGGTTTGATCATCGTCCACACCGGCAAGGGCAAGG
GCAAATCGACCGCGGGCTTCGGCATGATCTTTCGCCACATCGCCCACGGCATGCCCTGTGCCGTCGTTCAGTTCATCAAG
GGCGCCATGCACACCGGCGAGCGCGACCTGATCGAGAAACACTTCGGCGACATCTGCCAGTTCTACACGCTCGGCGAGGG
CTTCACTTGGGAAACGCAGGACCGCGCACGCGACATCGCCATGGCGGCCAAGGCCTGGGAGAAAGCCAAGGAACTCATCC
GCGACGAGCGCAACTCCATGGTCCTCCTCGACGAAATCAACATCGCCCTGCGCTATGACTACATCGACGTCGCCGAGGTC
GTTCGCTTTCTCAAGGAGGAGAAGCCGCACATGACGCATGTGGTCCTGACAGGCCGTAACGCCAAGGAGGACCTGATTGA
GATTGCAGATCTTGTGACGGAGATGGAATTGGTGAAGCATCCATTCCGCTCGGGTATCAAGGGCCAGAAGGGCGTCGAAT
TCTGA

Upstream 100 bases:

>100_bases
TGGAACCCGCGCTCCAATTCGGCGCGATTCGAACTGAACAGCCTTTCCGGCCGCGCGGCTACTGACCGCCTTCTGGCCGG
AAATCAATAGGGAGGACAAC

Downstream 100 bases:

>100_bases
TGACGCAGAGCTGGCAGTTCTGGGCGCTGCTGTCCGCGGCCTTCGCAGCGCTGACTGCCATCTTCGCCAAAGTCGGTGTC
GCCAATGTCAACTCCGATTT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSEEIANTGEPTAEKDEARHALKMAKKKTARDKIMATKTDEKGLIIVHTGKGKGKSTAGFGMIFRHIAHGMPCAVVQFIK
GAMHTGERDLIEKHFGDICQFYTLGEGFTWETQDRARDIAMAAKAWEKAKELIRDERNSMVLLDEINIALRYDYIDVAEV
VRFLKEEKPHMTHVVLTGRNAKEDLIEIADLVTEMELVKHPFRSGIKGQKGVEF

Sequences:

>Translated_214_residues
MSEEIANTGEPTAEKDEARHALKMAKKKTARDKIMATKTDEKGLIIVHTGKGKGKSTAGFGMIFRHIAHGMPCAVVQFIK
GAMHTGERDLIEKHFGDICQFYTLGEGFTWETQDRARDIAMAAKAWEKAKELIRDERNSMVLLDEINIALRYDYIDVAEV
VRFLKEEKPHMTHVVLTGRNAKEDLIEIADLVTEMELVKHPFRSGIKGQKGVEF
>Mature_213_residues
SEEIANTGEPTAEKDEARHALKMAKKKTARDKIMATKTDEKGLIIVHTGKGKGKSTAGFGMIFRHIAHGMPCAVVQFIKG
AMHTGERDLIEKHFGDICQFYTLGEGFTWETQDRARDIAMAAKAWEKAKELIRDERNSMVLLDEINIALRYDYIDVAEVV
RFLKEEKPHMTHVVLTGRNAKEDLIEIADLVTEMELVKHPFRSGIKGQKGVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=42.8571428571429, Blast_Score=170, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 24156; Mature: 24025

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEIANTGEPTAEKDEARHALKMAKKKTARDKIMATKTDEKGLIIVHTGKGKGKSTAGF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCHHH
GMIFRHIAHGMPCAVVQFIKGAMHTGERDLIEKHFGDICQFYTLGEGFTWETQDRARDIA
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MAAKAWEKAKELIRDERNSMVLLDEINIALRYDYIDVAEVVRFLKEEKPHMTHVVLTGRN
HHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCC
AKEDLIEIADLVTEMELVKHPFRSGIKGQKGVEF
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SEEIANTGEPTAEKDEARHALKMAKKKTARDKIMATKTDEKGLIIVHTGKGKGKSTAGF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCHHH
GMIFRHIAHGMPCAVVQFIKGAMHTGERDLIEKHFGDICQFYTLGEGFTWETQDRARDIA
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MAAKAWEKAKELIRDERNSMVLLDEINIALRYDYIDVAEVVRFLKEEKPHMTHVVLTGRN
HHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCC
AKEDLIEIADLVTEMELVKHPFRSGIKGQKGVEF
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]