Click here to switch to the map view.

The map label for this gene is siaT [H]

Identifier: 150396915

GI number: 150396915

Start: 1790447

End: 1792237

Strand: Direct

Name: siaT [H]

Synonym: Smed_1712

Alternate gene names: 150396915

Gene position: 1790447-1792237 (Clockwise)

Preceding gene: 150396914

Following gene: 150396917

Centisome position: 47.34

GC content: 62.53

Gene sequence:

>1791_bases
ATGATCGAGTTCGTCGCTGAAAACCTGGCGCCCATCATGTTCGTGTCGCTGATCGTGTTCCTTCTGCTCGGATACCCGGT
CGCCTTCTCGCTCGCCGCCAACGGTCTCCTGTTCTTCATAATCGGCGTCGAACTTGCGCCCTTGTCCGACTCCATCAATC
TCTCCTGGCCTCTGCTCAACGCACTGCCGGAACGGTTCTGGGGAGTCATGTCGAACGATACGCTCCTCGCCATTCCCTTC
TTCACTTTCATGGGCATAGTGCTCGAACGATCGGGCATGGCCGAGGACCTTCTCGACACCATCGGCCAGCTTTTCGGCCC
GGTGAGAGGCGGCCTTGCCTACGCCGTCATCTTCGTAGGCGCATTGCTTGCTGCCACGACCGGCGTCGTAGCGGCTTCCG
TCATCGCCATGGGCCTGATCTCACTGCCGATCATGCTGCGCTACGGCTACGACCGCCGCGTCGCTTCAGGCGTCATCGCC
GCCTCCGGCACGCTCGCCCAGATCATCCCACCGTCCCTCGTGCTGATCGTTCTCGCCGACCAGCTCGGCCGTTCCGTCGG
CGACATGTATGCCGGCGCGCTCATTCCCGGCCTTATTCTGACGAGTCTGTACATGGGCTACATTCTGCTCATGTCGTTCC
TGAAGCGTGACTCCATGCCGGCATTGCCGCTGGAAGCCCGCACGCTCGGTTCCGGCGTAACCTCGCTTCTCGTCGCGCTG
GTCGTCGCCGCAGGCATAGCCTATGCGGCCCATGTCTATTTTTCCCCGACGCAGGGAGAAAACGCAGACATCCTCGGAGC
GACGGTGGGCGTCCTGTTCATCTACCTGGTGGCGCTTGCCGACAGGGCGTTCAAGATCAACGCGCTTTCCCGGCTCGCTC
AGCAGGTAATCATCGTCTTGATCCCGCCGCTGGCTCTGATCTTCCTGGTTCTCGGTACGATCTTCCTCGGCATCGCCACC
CCGACGGAAGGCGGAGCCATGGGCGCCGTCGGCGCGCTCGTCATGGCGGCAGCCAAGGGCCGCCTGAGCATGGAGGTCAT
CCGCGCCGCGCTGGCCTCCACAACGAGGCTCTCCGCCTTCGTGCTGTTCATCCTGATCGGCGCCCGCGTCTTTTCGCTCA
CCTTCTACGGCGTCAACGGCCACCTCTGGGTGGAGCATCTGCTGACTGCGCTGCCTGGCGGAGAAATCGGCTTCCTGATC
GCCGTGAACGTGCTCGTCTTCTTCCTGGCGTTCTTCCTGGATTTCTTCGAACTCGCCTTCATCATCGTGCCGCTCCTCGC
ACCGGCAGCCGACAAGTTGGGGATCGACCTGATCTGGTTCGGCGTGCTGCTCGGCATCAACATGCAGACGAGCTTCATGC
ATCCGCCCTTCGGCTTCGCGCTGTTCTATCTGCGATCCGTGGCAGCCAGAGTGCCCTATCTGGACAAGGTGACCGGCAAA
AGGATGCAGCCGGTAACGACCGGGCAGATCTATTGGGGCGCCGTTCCTTTCGTCTGCATACAAATCATCATGGTTGCGCT
GACGCTGATGTTCCCGCAGATGGTCCTGCATTACAAAGGCACCGGCTCGGAGGTCGATCCGTCGACGATCAAGATCGAAG
TTCCGGGTTTCGGGTCCGGCGGCGGCGGGCTTACCCTGCCCGACAATGGCGGCGGTCTCGGCCTTCCCGGCGGCCTGCAG
CTGCCGGGCGGCAGCCCGCTCGACGAGAGCCGGCAGCCGGCCCAACCGGATACGGCGCCGAAGCAGAACAATACGGCACC
CGATCTCAGCGCGCCGCCATCGTTCAACTGA

Upstream 100 bases:

>100_bases
TCAAGAAAATCGCCATCATGACCGGCAACATGGACGATCCGACGCCTTATGTTCCTGCGCATGCACCGCTCGATGACGTC
GTATCGCCGGAGGCGCGTTC

Downstream 100 bases:

>100_bases
TATCGTTCCGCTATTCGCCGAAACAGTGAAGCCATCTGACGCTGTCAGATGGCTTCACTGCAATCATGAGCCTGATAGAT
TCCAAAAAATTAGAGCGGGA

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MIEFVAENLAPIMFVSLIVFLLLGYPVAFSLAANGLLFFIIGVELAPLSDSINLSWPLLNALPERFWGVMSNDTLLAIPF
FTFMGIVLERSGMAEDLLDTIGQLFGPVRGGLAYAVIFVGALLAATTGVVAASVIAMGLISLPIMLRYGYDRRVASGVIA
ASGTLAQIIPPSLVLIVLADQLGRSVGDMYAGALIPGLILTSLYMGYILLMSFLKRDSMPALPLEARTLGSGVTSLLVAL
VVAAGIAYAAHVYFSPTQGENADILGATVGVLFIYLVALADRAFKINALSRLAQQVIIVLIPPLALIFLVLGTIFLGIAT
PTEGGAMGAVGALVMAAAKGRLSMEVIRAALASTTRLSAFVLFILIGARVFSLTFYGVNGHLWVEHLLTALPGGEIGFLI
AVNVLVFFLAFFLDFFELAFIIVPLLAPAADKLGIDLIWFGVLLGINMQTSFMHPPFGFALFYLRSVAARVPYLDKVTGK
RMQPVTTGQIYWGAVPFVCIQIIMVALTLMFPQMVLHYKGTGSEVDPSTIKIEVPGFGSGGGGLTLPDNGGGLGLPGGLQ
LPGGSPLDESRQPAQPDTAPKQNNTAPDLSAPPSFN

Sequences:

>Translated_596_residues
MIEFVAENLAPIMFVSLIVFLLLGYPVAFSLAANGLLFFIIGVELAPLSDSINLSWPLLNALPERFWGVMSNDTLLAIPF
FTFMGIVLERSGMAEDLLDTIGQLFGPVRGGLAYAVIFVGALLAATTGVVAASVIAMGLISLPIMLRYGYDRRVASGVIA
ASGTLAQIIPPSLVLIVLADQLGRSVGDMYAGALIPGLILTSLYMGYILLMSFLKRDSMPALPLEARTLGSGVTSLLVAL
VVAAGIAYAAHVYFSPTQGENADILGATVGVLFIYLVALADRAFKINALSRLAQQVIIVLIPPLALIFLVLGTIFLGIAT
PTEGGAMGAVGALVMAAAKGRLSMEVIRAALASTTRLSAFVLFILIGARVFSLTFYGVNGHLWVEHLLTALPGGEIGFLI
AVNVLVFFLAFFLDFFELAFIIVPLLAPAADKLGIDLIWFGVLLGINMQTSFMHPPFGFALFYLRSVAARVPYLDKVTGK
RMQPVTTGQIYWGAVPFVCIQIIMVALTLMFPQMVLHYKGTGSEVDPSTIKIEVPGFGSGGGGLTLPDNGGGLGLPGGLQ
LPGGSPLDESRQPAQPDTAPKQNNTAPDLSAPPSFN
>Mature_596_residues
MIEFVAENLAPIMFVSLIVFLLLGYPVAFSLAANGLLFFIIGVELAPLSDSINLSWPLLNALPERFWGVMSNDTLLAIPF
FTFMGIVLERSGMAEDLLDTIGQLFGPVRGGLAYAVIFVGALLAATTGVVAASVIAMGLISLPIMLRYGYDRRVASGVIA
ASGTLAQIIPPSLVLIVLADQLGRSVGDMYAGALIPGLILTSLYMGYILLMSFLKRDSMPALPLEARTLGSGVTSLLVAL
VVAAGIAYAAHVYFSPTQGENADILGATVGVLFIYLVALADRAFKINALSRLAQQVIIVLIPPLALIFLVLGTIFLGIAT
PTEGGAMGAVGALVMAAAKGRLSMEVIRAALASTTRLSAFVLFILIGARVFSLTFYGVNGHLWVEHLLTALPGGEIGFLI
AVNVLVFFLAFFLDFFELAFIIVPLLAPAADKLGIDLIWFGVLLGINMQTSFMHPPFGFALFYLRSVAARVPYLDKVTGK
RMQPVTTGQIYWGAVPFVCIQIIMVALTLMFPQMVLHYKGTGSEVDPSTIKIEVPGFGSGGGGLTLPDNGGGLGLPGGLQ
LPGGSPLDESRQPAQPDTAPKQNNTAPDLSAPPSFN

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 62938; Mature: 62938

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFVAENLAPIMFVSLIVFLLLGYPVAFSLAANGLLFFIIGVELAPLSDSINLSWPLLN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCCCCHHHH
ALPERFWGVMSNDTLLAIPFFTFMGIVLERSGMAEDLLDTIGQLFGPVRGGLAYAVIFVG
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLAATTGVVAASVIAMGLISLPIMLRYGYDRRVASGVIAASGTLAQIIPPSLVLIVLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHH
QLGRSVGDMYAGALIPGLILTSLYMGYILLMSFLKRDSMPALPLEARTLGSGVTSLLVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHH
VVAAGIAYAAHVYFSPTQGENADILGATVGVLFIYLVALADRAFKINALSRLAQQVIIVL
HHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IPPLALIFLVLGTIFLGIATPTEGGAMGAVGALVMAAAKGRLSMEVIRAALASTTRLSAF
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VLFILIGARVFSLTFYGVNGHLWVEHLLTALPGGEIGFLIAVNVLVFFLAFFLDFFELAF
HHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IIVPLLAPAADKLGIDLIWFGVLLGINMQTSFMHPPFGFALFYLRSVAARVPYLDKVTGK
HHHHHHHCCHHHHCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCC
RMQPVTTGQIYWGAVPFVCIQIIMVALTLMFPQMVLHYKGTGSEVDPSTIKIEVPGFGSG
CCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCC
GGGLTLPDNGGGLGLPGGLQLPGGSPLDESRQPAQPDTAPKQNNTAPDLSAPPSFN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIEFVAENLAPIMFVSLIVFLLLGYPVAFSLAANGLLFFIIGVELAPLSDSINLSWPLLN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCCCCHHHH
ALPERFWGVMSNDTLLAIPFFTFMGIVLERSGMAEDLLDTIGQLFGPVRGGLAYAVIFVG
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLAATTGVVAASVIAMGLISLPIMLRYGYDRRVASGVIAASGTLAQIIPPSLVLIVLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHH
QLGRSVGDMYAGALIPGLILTSLYMGYILLMSFLKRDSMPALPLEARTLGSGVTSLLVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHH
VVAAGIAYAAHVYFSPTQGENADILGATVGVLFIYLVALADRAFKINALSRLAQQVIIVL
HHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IPPLALIFLVLGTIFLGIATPTEGGAMGAVGALVMAAAKGRLSMEVIRAALASTTRLSAF
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VLFILIGARVFSLTFYGVNGHLWVEHLLTALPGGEIGFLIAVNVLVFFLAFFLDFFELAF
HHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IIVPLLAPAADKLGIDLIWFGVLLGINMQTSFMHPPFGFALFYLRSVAARVPYLDKVTGK
HHHHHHHCCHHHHCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCC
RMQPVTTGQIYWGAVPFVCIQIIMVALTLMFPQMVLHYKGTGSEVDPSTIKIEVPGFGSG
CCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCC
GGGLTLPDNGGGLGLPGGLQLPGGSPLDESRQPAQPDTAPKQNNTAPDLSAPPSFN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]