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The map label for this gene is mhpC [C]

Identifier: 150396886

GI number: 150396886

Start: 1762667

End: 1763488

Strand: Direct

Name: mhpC [C]

Synonym: Smed_1681

Alternate gene names: 150396886

Gene position: 1762667-1763488 (Clockwise)

Preceding gene: 150396885

Following gene: 150396887

Centisome position: 46.61

GC content: 59.73

Gene sequence:

>822_bases
GTGGTTGAACCGATTTCCCAAGAGCATTTTTCAACGCTGAAGCGGACCGTCGTGCTGCCGAACGCGCTCCGGCTCGCGTA
TATCGAGATGGGCGACCCCAACGGCGTGCCCATCCTCCTGCTCCATGGTTTTACCGACAGCGCCCGAAGCTGGAGCCTCG
CCGCACCATATCTGGCGCCGGGTTTTCGCGTCGTAGCCGCAGACCTGCGGGGCCATGGGAATTCCGACCAGCCTGAGGGC
TGCTACACTATTCCCGAGCTGGCGAATGATGTCCGGTTGCTGATGGTGGCCTTGGACCTTGCGCCGTGCCACCTAGTCGG
CCATTCGCTTGGTGGACGGCTTGTGCAAGCGCTCGCTGAGCGGTGGCCCCATCTCGTCCGAAAAATCGTTCTTATGTCGA
CCTCCGCCGCACTGCGCGAGCGTCAGGGATGGTTGTGGGAAAACATCCAGATGCTCAGCGATCCGATCGATCCAGAAAGC
GCATTCATCCGGGAATGGTGCTCTGGCGCAGGTCTGATCGACGTGGATTTTCTGGCCCATGCGCGACGCGAAAGCGCCGC
CCTTCCGTCAAGAATCTGGCATTCGATCTATTACGAGCAGCTTGCCTACGATCCGTCGCCGCTTTTGCAGGATATTTCCG
CGGCGACGCTCATCCTGCGGGGCGAGAAGGACACGATCGCGACTGAGGAACATCAGGTCCAGATGAAAGACGCGATCGCC
GGCGCGGAGATCATTTCTCTTCCCGAGCACGGCCATAACATCCATTGGGAAGCCCCCGAAAAGGTGGCCCACTTGATTTT
GACGTTTCTCGATCGTCCGTGA

Upstream 100 bases:

>100_bases
TTCGCCATTACGCTGAGAGTTCCGATGCCGGCCCGAAGCGGACACTACAATAGCCACAGTTACAGGAACAATATGAATTC
AACCTTGAAGGTGGACGTGT

Downstream 100 bases:

>100_bases
CCGCGTTTGCGCTCTCTTAGCGTTCAAATCGACGGCGTGAACTTTCCGGCCTGACGGATCGAACCGGAAACATCGACCGA
AAGCCGCCGCTCTCCGATGG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Atropine acylhydrolase; Atropinesterase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MVEPISQEHFSTLKRTVVLPNALRLAYIEMGDPNGVPILLLHGFTDSARSWSLAAPYLAPGFRVVAADLRGHGNSDQPEG
CYTIPELANDVRLLMVALDLAPCHLVGHSLGGRLVQALAERWPHLVRKIVLMSTSAALRERQGWLWENIQMLSDPIDPES
AFIREWCSGAGLIDVDFLAHARRESAALPSRIWHSIYYEQLAYDPSPLLQDISAATLILRGEKDTIATEEHQVQMKDAIA
GAEIISLPEHGHNIHWEAPEKVAHLILTFLDRP

Sequences:

>Translated_273_residues
MVEPISQEHFSTLKRTVVLPNALRLAYIEMGDPNGVPILLLHGFTDSARSWSLAAPYLAPGFRVVAADLRGHGNSDQPEG
CYTIPELANDVRLLMVALDLAPCHLVGHSLGGRLVQALAERWPHLVRKIVLMSTSAALRERQGWLWENIQMLSDPIDPES
AFIREWCSGAGLIDVDFLAHARRESAALPSRIWHSIYYEQLAYDPSPLLQDISAATLILRGEKDTIATEEHQVQMKDAIA
GAEIISLPEHGHNIHWEAPEKVAHLILTFLDRP
>Mature_273_residues
MVEPISQEHFSTLKRTVVLPNALRLAYIEMGDPNGVPILLLHGFTDSARSWSLAAPYLAPGFRVVAADLRGHGNSDQPEG
CYTIPELANDVRLLMVALDLAPCHLVGHSLGGRLVQALAERWPHLVRKIVLMSTSAALRERQGWLWENIQMLSDPIDPES
AFIREWCSGAGLIDVDFLAHARRESAALPSRIWHSIYYEQLAYDPSPLLQDISAATLILRGEKDTIATEEHQVQMKDAIA
GAEIISLPEHGHNIHWEAPEKVAHLILTFLDRP

Specific function: Alkaloid degradation [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=283, Percent_Identity=28.6219081272085, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI13376164, Length=283, Percent_Identity=28.6219081272085, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI218777837, Length=281, Percent_Identity=25.9786476868327, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27597073, Length=304, Percent_Identity=21.7105263157895, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554012, Length=125, Percent_Identity=29.6, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.10 [H]

Molecular weight: Translated: 30358; Mature: 30358

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEPISQEHFSTLKRTVVLPNALRLAYIEMGDPNGVPILLLHGFTDSARSWSLAAPYLAP
CCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCC
GFRVVAADLRGHGNSDQPEGCYTIPELANDVRLLMVALDLAPCHLVGHSLGGRLVQALAE
CCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWPHLVRKIVLMSTSAALRERQGWLWENIQMLSDPIDPESAFIREWCSGAGLIDVDFLAH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEHHHHHH
ARRESAALPSRIWHSIYYEQLAYDPSPLLQDISAATLILRGEKDTIATEEHQVQMKDAIA
HHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHC
GAEIISLPEHGHNIHWEAPEKVAHLILTFLDRP
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVEPISQEHFSTLKRTVVLPNALRLAYIEMGDPNGVPILLLHGFTDSARSWSLAAPYLAP
CCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCC
GFRVVAADLRGHGNSDQPEGCYTIPELANDVRLLMVALDLAPCHLVGHSLGGRLVQALAE
CCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWPHLVRKIVLMSTSAALRERQGWLWENIQMLSDPIDPESAFIREWCSGAGLIDVDFLAH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEHHHHHH
ARRESAALPSRIWHSIYYEQLAYDPSPLLQDISAATLILRGEKDTIATEEHQVQMKDAIA
HHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHC
GAEIISLPEHGHNIHWEAPEKVAHLILTFLDRP
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA