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The map label for this gene is munIM [H]

Identifier: 150396872

GI number: 150396872

Start: 1755748

End: 1757271

Strand: Reverse

Name: munIM [H]

Synonym: Smed_1667

Alternate gene names: 150396872

Gene position: 1757271-1755748 (Counterclockwise)

Preceding gene: 150396873

Following gene: 150396871

Centisome position: 46.47

GC content: 66.93

Gene sequence:

>1524_bases
GTGAGCGATCAGCTTCCGAAGCTTGGGCCGAAGGCGCGCGAGATCGTCGACGCAGTGTTGCAAGCGGGTGTCTATCGTGC
GGAGAAACAATCCGATGTCGTCGCATGTCGCAGCCTGAACGGCCGCGGGCTGATTGGTCGTGACAAGAAAGATGGTACGG
TCTGGTATCCGACGGCAAAGCTTTGCGAGCTCGCCGGCGTGACGCCGCCGGAGATCGGGCAGGGGGGCGAGGGCGGAACC
GGCGCGCCGGATTCTCGGGTTCAACCCGAGGAGGGCGCCGATCGCCTCCCTGCGCCGGCCGAGATCGATGCTTCGCCGAC
GGCGTACCTGCCGCCGCTCACGCGCCTGCCGCATCATCCGCTCGCCGCTCTTTTCCCCATGCTACCCGACGACGAGCTGC
GCCGCCTCGCGGGCGATATCGAGGCGAACGGGCAGCAGGAGCCGGTCTGGCTGCTCGACGGCAAGATCCTCGACGGGCGG
AACCGCGAGGCGGCTTGCCATCTGGTCGGGATCGACGCCTGGACGAAGGAATACGAGGGCAAGGACCCGCTCGGCTTCGT
GCTCTCGCTCAACCTGCATCGCCGGCACCTGACGGAAAGCCAGCGCGCCATGGTGGCGGCGCGGATCGTCGATTGGGAAC
GCGGCATCAACCAGAGCACAGCCGGGGATGCAAATTTGCACGCCCGCGAGGCAGGGCGCCGGCTTTCGATTTCCGAGCGC
GCGGTCAAGGCCGCAAAGCGGGTGCGCGACCACGGTGTCGAGGCGCTGTCCGATGCCATCCGCGACGGGCGGATCTCCGT
CCATGCCGGCGAGGCTTTGAGCCACCTGGAGCGGGCGGCGCAGGAGGAGGCGCTGCGGCTCGAGGAAAAGGAGATCATCC
AGCGCGCCAAGGAAATTCGCCAGAAGCGGCAGGAGATCCGTCATGCCGTGCGGCTGACGCATATGGCGCATGTGGCAGAG
ACCGGCTCGTCGACTGCGGGCAAGGTTGGCCAGAAGTTCCCGGTGATCTATGCCGATCCGCCGTGGCAGTTCGGGGTGCG
CTCGGAAGTGACGGGGCGCGAGAAGAGCGCCGAGAACCATTATCCGACCATGCCAACGGATGCGATCTGCGCGCTCTTCG
ACGAGATCGGGGCGCCGGCCAAGGCGGATGCGGTCCTCTTCCTCTGGGCGACGAACCCGATGCTGCCCGACGCATTCCGC
GTCATGGCGGCATGGGGCTTCACCTATGTGCACCACTGGATCTGGGACAAGGAAGTTGCCGGAACCGGCTATTGGGGCCG
CGATCGGCACGAGCTGCTGCTGATCGGCAGGCGCGGCGACCCGGTTTCGCCGCTGCCCGGCTCGCAGCCGGAGACGGTCT
ATCGCGAGCGGAAGGGCAGGCATAGCGCCAAGCCCGATTACTTCGCCGAGCAGATCGAGCGGCTCTATCCCGCCATGCCA
CGGCTCGAAATGTTCTGCCGCAGCCCGCGCCCGGGCTGGACGGCATGGGGGTTTGAAGCCGCGACAGAGGAGGCAGCTGA
ATGA

Upstream 100 bases:

>100_bases
GGCTCCACGAAAACCGCGACACGCACTCGATCGCCACCGAACTTGGTATCGACGGGGACGAGGTCTGCAAGATCATCGAA
CAATCGGAAGGAAGAAGGCC

Downstream 100 bases:

>100_bases
CCTCCATGCTTCCCATCATCGAGGAACTCGCCGATGCGCCGGACCACAAGGCGCGGGCGCGCTGGCTGCTGGAAGTGCCG
CTCGCGGTGATCATCCGCGA

Product: MT-A70 family protein

Products: NA

Alternate protein names: Adenine-specific methyltransferase MunI; M.MunI [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSDQLPKLGPKAREIVDAVLQAGVYRAEKQSDVVACRSLNGRGLIGRDKKDGTVWYPTAKLCELAGVTPPEIGQGGEGGT
GAPDSRVQPEEGADRLPAPAEIDASPTAYLPPLTRLPHHPLAALFPMLPDDELRRLAGDIEANGQQEPVWLLDGKILDGR
NREAACHLVGIDAWTKEYEGKDPLGFVLSLNLHRRHLTESQRAMVAARIVDWERGINQSTAGDANLHAREAGRRLSISER
AVKAAKRVRDHGVEALSDAIRDGRISVHAGEALSHLERAAQEEALRLEEKEIIQRAKEIRQKRQEIRHAVRLTHMAHVAE
TGSSTAGKVGQKFPVIYADPPWQFGVRSEVTGREKSAENHYPTMPTDAICALFDEIGAPAKADAVLFLWATNPMLPDAFR
VMAAWGFTYVHHWIWDKEVAGTGYWGRDRHELLLIGRRGDPVSPLPGSQPETVYRERKGRHSAKPDYFAEQIERLYPAMP
RLEMFCRSPRPGWTAWGFEAATEEAAE

Sequences:

>Translated_507_residues
MSDQLPKLGPKAREIVDAVLQAGVYRAEKQSDVVACRSLNGRGLIGRDKKDGTVWYPTAKLCELAGVTPPEIGQGGEGGT
GAPDSRVQPEEGADRLPAPAEIDASPTAYLPPLTRLPHHPLAALFPMLPDDELRRLAGDIEANGQQEPVWLLDGKILDGR
NREAACHLVGIDAWTKEYEGKDPLGFVLSLNLHRRHLTESQRAMVAARIVDWERGINQSTAGDANLHAREAGRRLSISER
AVKAAKRVRDHGVEALSDAIRDGRISVHAGEALSHLERAAQEEALRLEEKEIIQRAKEIRQKRQEIRHAVRLTHMAHVAE
TGSSTAGKVGQKFPVIYADPPWQFGVRSEVTGREKSAENHYPTMPTDAICALFDEIGAPAKADAVLFLWATNPMLPDAFR
VMAAWGFTYVHHWIWDKEVAGTGYWGRDRHELLLIGRRGDPVSPLPGSQPETVYRERKGRHSAKPDYFAEQIERLYPAMP
RLEMFCRSPRPGWTAWGFEAATEEAAE
>Mature_506_residues
SDQLPKLGPKAREIVDAVLQAGVYRAEKQSDVVACRSLNGRGLIGRDKKDGTVWYPTAKLCELAGVTPPEIGQGGEGGTG
APDSRVQPEEGADRLPAPAEIDASPTAYLPPLTRLPHHPLAALFPMLPDDELRRLAGDIEANGQQEPVWLLDGKILDGRN
REAACHLVGIDAWTKEYEGKDPLGFVLSLNLHRRHLTESQRAMVAARIVDWERGINQSTAGDANLHAREAGRRLSISERA
VKAAKRVRDHGVEALSDAIRDGRISVHAGEALSHLERAAQEEALRLEEKEIIQRAKEIRQKRQEIRHAVRLTHMAHVAET
GSSTAGKVGQKFPVIYADPPWQFGVRSEVTGREKSAENHYPTMPTDAICALFDEIGAPAKADAVLFLWATNPMLPDAFRV
MAAWGFTYVHHWIWDKEVAGTGYWGRDRHELLLIGRRGDPVSPLPGSQPETVYRERKGRHSAKPDYFAEQIERLYPAMPR
LEMFCRSPRPGWTAWGFEAATEEAAE

Specific function: This methylase recognizes the double-stranded sequence CAATTG, causes specific methylation on A-3 on both strands, and protects the DNA from cleavage by the MunI endonuclease [H]

COG id: COG4725

COG function: function code TK; Transcriptional activator, adenine-specific DNA methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MT-A70-like family [H]

Homologues:

Organism=Drosophila melanogaster, GI21355141, Length=177, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR007757 [H]

Pfam domain/function: PF05063 MT-A70 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 56193; Mature: 56062

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00092 N6_MTASE ; PS51143 MT_A70

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQLPKLGPKAREIVDAVLQAGVYRAEKQSDVVACRSLNGRGLIGRDKKDGTVWYPTAK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCEEECCHHH
LCELAGVTPPEIGQGGEGGTGAPDSRVQPEEGADRLPAPAEIDASPTAYLPPLTRLPHHP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCC
LAALFPMLPDDELRRLAGDIEANGQQEPVWLLDGKILDGRNREAACHLVGIDAWTKEYEG
HHHHHCCCCHHHHHHHHCCCCCCCCCCCEEEECCEEECCCCCCCEEEEEECHHHHHHCCC
KDPLGFVLSLNLHRRHLTESQRAMVAARIVDWERGINQSTAGDANLHAREAGRRLSISER
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHH
AVKAAKRVRDHGVEALSDAIRDGRISVHAGEALSHLERAAQEEALRLEEKEIIQRAKEIR
HHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKRQEIRHAVRLTHMAHVAETGSSTAGKVGQKFPVIYADPPWQFGVRSEVTGREKSAENH
HHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
YPTMPTDAICALFDEIGAPAKADAVLFLWATNPMLPDAFRVMAAWGFTYVHHWIWDKEVA
CCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GTGYWGRDRHELLLIGRRGDPVSPLPGSQPETVYRERKGRHSAKPDYFAEQIERLYPAMP
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCH
RLEMFCRSPRPGWTAWGFEAATEEAAE
HHHHHHCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SDQLPKLGPKAREIVDAVLQAGVYRAEKQSDVVACRSLNGRGLIGRDKKDGTVWYPTAK
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCEEECCHHH
LCELAGVTPPEIGQGGEGGTGAPDSRVQPEEGADRLPAPAEIDASPTAYLPPLTRLPHHP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCC
LAALFPMLPDDELRRLAGDIEANGQQEPVWLLDGKILDGRNREAACHLVGIDAWTKEYEG
HHHHHCCCCHHHHHHHHCCCCCCCCCCCEEEECCEEECCCCCCCEEEEEECHHHHHHCCC
KDPLGFVLSLNLHRRHLTESQRAMVAARIVDWERGINQSTAGDANLHAREAGRRLSISER
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHH
AVKAAKRVRDHGVEALSDAIRDGRISVHAGEALSHLERAAQEEALRLEEKEIIQRAKEIR
HHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKRQEIRHAVRLTHMAHVAETGSSTAGKVGQKFPVIYADPPWQFGVRSEVTGREKSAENH
HHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
YPTMPTDAICALFDEIGAPAKADAVLFLWATNPMLPDAFRVMAAWGFTYVHHWIWDKEVA
CCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GTGYWGRDRHELLLIGRRGDPVSPLPGSQPETVYRERKGRHSAKPDYFAEQIERLYPAMP
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCH
RLEMFCRSPRPGWTAWGFEAATEEAAE
HHHHHHCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8181741 [H]