Click here to switch to the map view.

The map label for this gene is mcpA [H]

Identifier: 150396822

GI number: 150396822

Start: 1707483

End: 1709294

Strand: Reverse

Name: mcpA [H]

Synonym: Smed_1613

Alternate gene names: 150396822

Gene position: 1709294-1707483 (Counterclockwise)

Preceding gene: 150396825

Following gene: 150396821

Centisome position: 45.2

GC content: 63.13

Gene sequence:

>1812_bases
ATGAGAAGAATTCGGATTTCGGCGCGTCTTTACGCGCTGGTGGCGTTTGCGCTGCTGACGATGGCGGCGGCGCTGACCTT
CGGACTGGTTCAGGCGCAGGACAGGCTGGTCGCCGAGCGGAAGGCCATGCTCGCGGCGATGAACGAGAACGCAATCACAG
TGTTCAATGCCTATCACGGCCAGGAAAAGGCCGGAAGGGTGTCGCGCAAAGAAGCACAGAGCCGCGCCCTGGAGGCGGTC
AGGGCTATGCGCTATCAGGAAAGCGGCTATTTCTGGGTGAACGATATGCATCCGACAATGGTGATGCATCCCATTAAACC
TGAACTCGATGGCGCCGACCTGACGCAGAACAAGGATCCAAACGGCAAGTTCCTGTTCGTTGAGTTCGTGAAGACGGTTG
AAGCACATGGAAAGGGCTTCGTCGACTATTACTGGCCGAAGCCCGGCGCGGACGAGCCTGTGCTTAAGTATTCGCATGTG
GCCGGTTTCGAGCCCTGGGGATGGGTGGTCGGTACCGGTGTTTACGCCGACGATCTCGCCGCCATGTTCCGCGAGCGCGC
ATGGCAGATGGCCGGCATTCTGGCCGCGGCCGCGCTTGCGATCCTCATGGCGGCATTGGCTATCGTGCGCAGCGTGGTCC
GGCCCATCGAAAAGCTGAAGATCTCGATGCGGGCGATCGCGGACGAGAACCTTTCCCTGGATGTTCCGGAAACCGATCGC
GCCGACGAGATCGGGCAGATGGCGAAGGTGCTGGTCGTGTTGCGCGACTCGGTCAAGGAGCGATTAGAGCTTCGTTCGCG
CGAGGCGGAACAGCAGGACCGTCTGGATTCCGAACGGCGCGGCAATGAAGAGCTCCAGCGAAAGACTGCCGCGATCCAGG
CCGAGGCGATGGAGACACTCGGGGCGGCTCTGGAGCGGCTGGCAAGCGGCGACCTGACCGCCGAGGTCGCGCGGATCGCG
CCGGAATACACCAAGCTCAAGGACGACTTCAACACGGCCGCCGCGGCGCTTCGCGACGTCATTGGCGCGATCTCCCAATC
GACCGAAATCGTCCATGGCAGCGCCGCCGATATCTCGGAAGCGGCCAACAACCTGTCGCGCCGTACGGAGCAGCAGGCGG
CGGCTCTTGAGGAAACGGCAGCCGCACTTGATGAGATAACCTCCACCGTACGCCATGCGTCGGACCGCGCCCATGAAGCG
CGCGACATGGTAGACGAGACGAAGGCGAGTGCCGCGAAATCCGGCGGCATCGTCCGCAATGCGATCGATGCCATGGGGCG
GATCGAAGCGTCGTCCAGCCGGATCAGCCAGATCATCGGGGTGATCGACGAGATCGCCTTCCAGACGAACCTGCTCGCGC
TCAATGCAGGCGTCGAGGCGGCGCGGGCAGGGGAAGCCGGACGCGGCTTCGCGGTCGTTGCCCAGGAGGTTCGCGAGCTC
GCACAACGCTCGGCCGGCGCGGCAAAGGAAATCAAGGACCTGATAGCCACTTCGGTCAAGGAGGTCGGTGCCGGCGTCGA
ACTCGTCCGCTCGACGGGCGACGCGCTGATGGAGATCGAGTCCCTGGTCAACCGCGTCAATGAACAGGTGGCTTCCATCG
CAACCGCGGCTCGGGAACAGGCAACCGGACTGCAGGAGGTAAACACAGCCGTCAACAGCATGGATCAGATGACGCAGCAG
AATGCGGCCATGGTCGAGGAGACGACCGCGGCAAGCCAGACGCTGGCGCAGGAAAGCCGCGAGTTGAAGGCGCTGCTCGG
ACAGTTCCGGCTGCAGGAGGGCGCGCAGCCGGCATATGGCAGAGCAGCCTAA

Upstream 100 bases:

>100_bases
TTTCTTCGTTAATTCGAGCATCCTCAAATCTAGTGATCGTTTGTTAGGAGCTTTGCAAATAGCTACTTATAATCTGCACG
CCTCGGAATGGAGGCAGGGG

Downstream 100 bases:

>100_bases
CGCCCCATCAGCATTGTATCGTTGAGGAGCCCGGCGTCGAAAGACGCGCGGGCTCCTCGCCCGATCGATAAGGCGGGGGG
TATGCCTGCTCCTATCGGTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MRRIRISARLYALVAFALLTMAAALTFGLVQAQDRLVAERKAMLAAMNENAITVFNAYHGQEKAGRVSRKEAQSRALEAV
RAMRYQESGYFWVNDMHPTMVMHPIKPELDGADLTQNKDPNGKFLFVEFVKTVEAHGKGFVDYYWPKPGADEPVLKYSHV
AGFEPWGWVVGTGVYADDLAAMFRERAWQMAGILAAAALAILMAALAIVRSVVRPIEKLKISMRAIADENLSLDVPETDR
ADEIGQMAKVLVVLRDSVKERLELRSREAEQQDRLDSERRGNEELQRKTAAIQAEAMETLGAALERLASGDLTAEVARIA
PEYTKLKDDFNTAAAALRDVIGAISQSTEIVHGSAADISEAANNLSRRTEQQAAALEETAAALDEITSTVRHASDRAHEA
RDMVDETKASAAKSGGIVRNAIDAMGRIEASSSRISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
AQRSAGAAKEIKDLIATSVKEVGAGVELVRSTGDALMEIESLVNRVNEQVASIATAAREQATGLQEVNTAVNSMDQMTQQ
NAAMVEETTAASQTLAQESRELKALLGQFRLQEGAQPAYGRAA

Sequences:

>Translated_603_residues
MRRIRISARLYALVAFALLTMAAALTFGLVQAQDRLVAERKAMLAAMNENAITVFNAYHGQEKAGRVSRKEAQSRALEAV
RAMRYQESGYFWVNDMHPTMVMHPIKPELDGADLTQNKDPNGKFLFVEFVKTVEAHGKGFVDYYWPKPGADEPVLKYSHV
AGFEPWGWVVGTGVYADDLAAMFRERAWQMAGILAAAALAILMAALAIVRSVVRPIEKLKISMRAIADENLSLDVPETDR
ADEIGQMAKVLVVLRDSVKERLELRSREAEQQDRLDSERRGNEELQRKTAAIQAEAMETLGAALERLASGDLTAEVARIA
PEYTKLKDDFNTAAAALRDVIGAISQSTEIVHGSAADISEAANNLSRRTEQQAAALEETAAALDEITSTVRHASDRAHEA
RDMVDETKASAAKSGGIVRNAIDAMGRIEASSSRISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
AQRSAGAAKEIKDLIATSVKEVGAGVELVRSTGDALMEIESLVNRVNEQVASIATAAREQATGLQEVNTAVNSMDQMTQQ
NAAMVEETTAASQTLAQESRELKALLGQFRLQEGAQPAYGRAA
>Mature_603_residues
MRRIRISARLYALVAFALLTMAAALTFGLVQAQDRLVAERKAMLAAMNENAITVFNAYHGQEKAGRVSRKEAQSRALEAV
RAMRYQESGYFWVNDMHPTMVMHPIKPELDGADLTQNKDPNGKFLFVEFVKTVEAHGKGFVDYYWPKPGADEPVLKYSHV
AGFEPWGWVVGTGVYADDLAAMFRERAWQMAGILAAAALAILMAALAIVRSVVRPIEKLKISMRAIADENLSLDVPETDR
ADEIGQMAKVLVVLRDSVKERLELRSREAEQQDRLDSERRGNEELQRKTAAIQAEAMETLGAALERLASGDLTAEVARIA
PEYTKLKDDFNTAAAALRDVIGAISQSTEIVHGSAADISEAANNLSRRTEQQAAALEETAAALDEITSTVRHASDRAHEA
RDMVDETKASAAKSGGIVRNAIDAMGRIEASSSRISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
AQRSAGAAKEIKDLIATSVKEVGAGVELVRSTGDALMEIESLVNRVNEQVASIATAAREQATGLQEVNTAVNSMDQMTQQ
NAAMVEETTAASQTLAQESRELKALLGQFRLQEGAQPAYGRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=296, Percent_Identity=44.2567567567568, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1787690, Length=308, Percent_Identity=40.9090909090909, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI2367378, Length=298, Percent_Identity=43.9597315436242, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1788195, Length=256, Percent_Identity=45.703125, Blast_Score=195, Evalue=9e-51,
Organism=Escherichia coli, GI1789453, Length=248, Percent_Identity=37.0967741935484, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 65305; Mature: 65305

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIRISARLYALVAFALLTMAAALTFGLVQAQDRLVAERKAMLAAMNENAITVFNAYHG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
QEKAGRVSRKEAQSRALEAVRAMRYQESGYFWVNDMHPTMVMHPIKPELDGADLTQNKDP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCC
NGKFLFVEFVKTVEAHGKGFVDYYWPKPGADEPVLKYSHVAGFEPWGWVVGTGVYADDLA
CCCEEHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHCCCCCCCHHHCCCCHHHHHH
AMFRERAWQMAGILAAAALAILMAALAIVRSVVRPIEKLKISMRAIADENLSLDVPETDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCC
ADEIGQMAKVLVVLRDSVKERLELRSREAEQQDRLDSERRGNEELQRKTAAIQAEAMETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHH
GAALERLASGDLTAEVARIAPEYTKLKDDFNTAAAALRDVIGAISQSTEIVHGSAADISE
HHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHH
AANNLSRRTEQQAAALEETAAALDEITSTVRHASDRAHEARDMVDETKASAAKSGGIVRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AIDAMGRIEASSSRISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSAGAAKEIKDLIATSVKEVGAGVELVRSTGDALMEIESLVNRVNEQVASIATAAREQ
HHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGLQEVNTAVNSMDQMTQQNAAMVEETTAASQTLAQESRELKALLGQFRLQEGAQPAYG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RAA
CCC
>Mature Secondary Structure
MRRIRISARLYALVAFALLTMAAALTFGLVQAQDRLVAERKAMLAAMNENAITVFNAYHG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
QEKAGRVSRKEAQSRALEAVRAMRYQESGYFWVNDMHPTMVMHPIKPELDGADLTQNKDP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCC
NGKFLFVEFVKTVEAHGKGFVDYYWPKPGADEPVLKYSHVAGFEPWGWVVGTGVYADDLA
CCCEEHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHCCCCCCCHHHCCCCHHHHHH
AMFRERAWQMAGILAAAALAILMAALAIVRSVVRPIEKLKISMRAIADENLSLDVPETDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCC
ADEIGQMAKVLVVLRDSVKERLELRSREAEQQDRLDSERRGNEELQRKTAAIQAEAMETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHH
GAALERLASGDLTAEVARIAPEYTKLKDDFNTAAAALRDVIGAISQSTEIVHGSAADISE
HHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHH
AANNLSRRTEQQAAALEETAAALDEITSTVRHASDRAHEARDMVDETKASAAKSGGIVRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AIDAMGRIEASSSRISQIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSAGAAKEIKDLIATSVKEVGAGVELVRSTGDALMEIESLVNRVNEQVASIATAAREQ
HHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGLQEVNTAVNSMDQMTQQNAAMVEETTAASQTLAQESRELKALLGQFRLQEGAQPAYG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]