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The map label for this gene is gpt [H]

Identifier: 150396600

GI number: 150396600

Start: 1461420

End: 1461917

Strand: Direct

Name: gpt [H]

Synonym: Smed_1386

Alternate gene names: 150396600

Gene position: 1461420-1461917 (Clockwise)

Preceding gene: 150396599

Following gene: 150396602

Centisome position: 38.64

GC content: 59.44

Gene sequence:

>498_bases
ATGTCTCTTCCCGAGAAAGCCTTTCCCGTATCCTGGGATCAATTCCATCGCGACGCCCGCGCTCTGGCCTGGCGGCTAGC
GGATAACGGACAGGAATGGCGCGCGATGGTTTGCATCACGCGCGGCGGCCTTGTTCCGGCCGCGATCGTAAGCCGGGAAC
TTAACATCCGGATGATCGAAACGGTCTGCATCGCCTCCTATCACGACTACGATACGCAAGGTCAGATGAAGGTGCTGAAG
AGCATCTCACCGGAGATCGCCAAGAGCGGCGGCGAAGGCGTTCTCATCGTCGACGATTTGACAGACACCGGCAAAACCGC
CGCCGAGGTTCGCGCGATGCTGCCAAAGGCGCATTTCGCCGCCGTCTACGCAAAGCCGAAAGGGCGTCCGCTGGTCGATA
CTTTCGTTACCGAGGTCAGCCAGGATACTTGGATCTACTTCCCTTGGGATCTGGGCTTCACCTACCAGGAGCCTATCGCC
AAGGGCACACGCGGTTAG

Upstream 100 bases:

>100_bases
TTCATTGCCGTTATTGCATCAGACACGAAAGCGTCGGCCGTGTGGCCGCCGACCTGCAGCAACGCTTGCCACGGACAGTG
GAAAGAAGCCGGAGCCCGCC

Downstream 100 bases:

>100_bases
AACACGTTCGGGGAAAGATCGGAGCATTTTCTCAAAGCGGCGGCATGCTTTCGATGAGCATTTCGGCCGTCGCCGTACGG
CCAGCTGCGACACCTGCTTC

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSLPEKAFPVSWDQFHRDARALAWRLADNGQEWRAMVCITRGGLVPAAIVSRELNIRMIETVCIASYHDYDTQGQMKVLK
SISPEIAKSGGEGVLIVDDLTDTGKTAAEVRAMLPKAHFAAVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFTYQEPIA
KGTRG

Sequences:

>Translated_165_residues
MSLPEKAFPVSWDQFHRDARALAWRLADNGQEWRAMVCITRGGLVPAAIVSRELNIRMIETVCIASYHDYDTQGQMKVLK
SISPEIAKSGGEGVLIVDDLTDTGKTAAEVRAMLPKAHFAAVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFTYQEPIA
KGTRG
>Mature_164_residues
SLPEKAFPVSWDQFHRDARALAWRLADNGQEWRAMVCITRGGLVPAAIVSRELNIRMIETVCIASYHDYDTQGQMKVLKS
ISPEIAKSGGEGVLIVDDLTDTGKTAAEVRAMLPKAHFAAVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFTYQEPIAK
GTRG

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=155, Percent_Identity=48.3870967741936, Blast_Score=160, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 18374; Mature: 18243

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPEKAFPVSWDQFHRDARALAWRLADNGQEWRAMVCITRGGLVPAAIVSRELNIRMIE
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHCCCCEEEEH
TVCIASYHDYDTQGQMKVLKSISPEIAKSGGEGVLIVDDLTDTGKTAAEVRAMLPKAHFA
HEEHHHCCCCCCCHHHHHHHHCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEE
AVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFTYQEPIAKGTRG
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLPEKAFPVSWDQFHRDARALAWRLADNGQEWRAMVCITRGGLVPAAIVSRELNIRMIE
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHCCCCEEEEH
TVCIASYHDYDTQGQMKVLKSISPEIAKSGGEGVLIVDDLTDTGKTAAEVRAMLPKAHFA
HEEHHHCCCCCCCHHHHHHHHCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEE
AVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFTYQEPIAKGTRG
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]