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The map label for this gene is mdtJ [H]

Identifier: 150396576

GI number: 150396576

Start: 1442494

End: 1442838

Strand: Direct

Name: mdtJ [H]

Synonym: Smed_1360

Alternate gene names: 150396576

Gene position: 1442494-1442838 (Clockwise)

Preceding gene: 150396574

Following gene: 150396577

Centisome position: 38.14

GC content: 58.55

Gene sequence:

>345_bases
ATGCGCCTTGCATGGTTTTTCCTGGTACTCGCGATTGTGACCGAAGTCGTCGGCCTGACGGTAATGAAGGCTGCGTCCGG
TTCCGGCACCTATTGGGGGCATATCATTATGTATGCCTCGATCGCGCTCTCCTACGTCTTCCTGGCACGAGCAGTTAAGG
TTATTCCGGTCGGTGTCGCCTATGCCGTGTGGGAAGGGTCCGGTGTTGCTGTGATAACGCTCGTTTCTGTTTTCGCTTTC
GGCCGCGCCCTCTCCGGCCGTGAGATGCTCGGCCTCGCGATGGCCGTCGCCGGAATCCTCCTCGTCAATGCGGGTAAGGG
CAAGGGTGAGGAAACAGACGCATGA

Upstream 100 bases:

>100_bases
CGAGAAGATGCTGCTAGTTTGCGCCGAACACGTCGACCGTCGTGACCCGATCGTGCAACCGCTGCTGGACCGCTTCTCGG
CCTTATTCTCGTAGGTTTTC

Downstream 100 bases:

>100_bases
GCGCGTCGGGTCTCTCTTTTGCCTTCGCGGTGGCGGCGGGCGTTCTCGACGTGGCCGCGAATCTCGCCTCGACCAAATCG
CACGGCTTCGCCCGTCGCGG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MRLAWFFLVLAIVTEVVGLTVMKAASGSGTYWGHIIMYASIALSYVFLARAVKVIPVGVAYAVWEGSGVAVITLVSVFAF
GRALSGREMLGLAMAVAGILLVNAGKGKGEETDA

Sequences:

>Translated_114_residues
MRLAWFFLVLAIVTEVVGLTVMKAASGSGTYWGHIIMYASIALSYVFLARAVKVIPVGVAYAVWEGSGVAVITLVSVFAF
GRALSGREMLGLAMAVAGILLVNAGKGKGEETDA
>Mature_114_residues
MRLAWFFLVLAIVTEVVGLTVMKAASGSGTYWGHIIMYASIALSYVFLARAVKVIPVGVAYAVWEGSGVAVITLVSVFAF
GRALSGREMLGLAMAVAGILLVNAGKGKGEETDA

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=113, Percent_Identity=46.9026548672566, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI1786755, Length=96, Percent_Identity=38.5416666666667, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11896; Mature: 11896

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAWFFLVLAIVTEVVGLTVMKAASGSGTYWGHIIMYASIALSYVFLARAVKVIPVGVA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YAVWEGSGVAVITLVSVFAFGRALSGREMLGLAMAVAGILLVNAGKGKGEETDA
EEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCC
>Mature Secondary Structure
MRLAWFFLVLAIVTEVVGLTVMKAASGSGTYWGHIIMYASIALSYVFLARAVKVIPVGVA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YAVWEGSGVAVITLVSVFAFGRALSGREMLGLAMAVAGILLVNAGKGKGEETDA
EEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA