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The map label for this gene is ssb [H]

Identifier: 150396454

GI number: 150396454

Start: 1322921

End: 1323433

Strand: Direct

Name: ssb [H]

Synonym: Smed_1236

Alternate gene names: 150396454

Gene position: 1322921-1323433 (Clockwise)

Preceding gene: 150396443

Following gene: 150396459

Centisome position: 34.98

GC content: 61.21

Gene sequence:

>513_bases
ATGGCTGGTAGCGTCAACAAGGTGATCTTGATCGGAAATGTCGGGGCCGACCCGGAAATCCGGCGCACGCAGGATGGCCG
GCCGATTGCCAATCTCAGAATTGCCACCTCCGAAAGCTGGCGCGACCGTAACTCCGGCGAGCGCCGGGAGAAGACGGAAT
GGCATACTGTCGTCGTCTTCAACGAGGGTCTTTGCAAAGTCATCGAGCAATATGTGAAAAAGGGCGCCAAACTCTATATC
GAAGGCCAGTTGCAGACCCGCAAATGGCAGGACCAGAACGGCAATGACCGCTATTCGACCGAGATCGTCCTGCAGGGCTT
CAATTCGACGCTGACGATGCTAGACGGCCGCGGCGAGGGCGGCGGTGCGAGCCGCGGCGGCAGCGATCTCGGAGGCGGCG
GATACGAGGAATACGATCAGTCGCGGGGGCAATCGTCAGGCGCCCGGTCGGGCGGCCAGTCGAACCAGGGCGGCAACTTC
TCGCGCGATCTCGACGACGACATTCCGTTCTGA

Upstream 100 bases:

>100_bases
GAAGCGGGGCGTATCGGCGGCAGCGGGCCGCTAAGGTGTTCGCTCGTGAGACATTGGAGAGCCGGGCTCGCGGTCCGGCG
GCAAAAACGGGAAAAGCGAC

Downstream 100 bases:

>100_bases
TCGACGACGGCAGCAACGCTGCGATCATCGGCCCGCTTCGTTGCGGGCCGACGACGTCCGCGAGGAAGCCACTTATCTGC
CCTGTCGAACTGCATCCTGT

Product: single-stranded DNA-binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MAGSVNKVILIGNVGADPEIRRTQDGRPIANLRIATSESWRDRNSGERREKTEWHTVVVFNEGLCKVIEQYVKKGAKLYI
EGQLQTRKWQDQNGNDRYSTEIVLQGFNSTLTMLDGRGEGGGASRGGSDLGGGGYEEYDQSRGQSSGARSGGQSNQGGNF
SRDLDDDIPF

Sequences:

>Translated_170_residues
MAGSVNKVILIGNVGADPEIRRTQDGRPIANLRIATSESWRDRNSGERREKTEWHTVVVFNEGLCKVIEQYVKKGAKLYI
EGQLQTRKWQDQNGNDRYSTEIVLQGFNSTLTMLDGRGEGGGASRGGSDLGGGGYEEYDQSRGQSSGARSGGQSNQGGNF
SRDLDDDIPF
>Mature_169_residues
AGSVNKVILIGNVGADPEIRRTQDGRPIANLRIATSESWRDRNSGERREKTEWHTVVVFNEGLCKVIEQYVKKGAKLYIE
GQLQTRKWQDQNGNDRYSTEIVLQGFNSTLTMLDGRGEGGGASRGGSDLGGGGYEEYDQSRGQSSGARSGGQSNQGGNFS
RDLDDDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=108, Percent_Identity=37.962962962963, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1790494, Length=186, Percent_Identity=45.6989247311828, Blast_Score=142, Evalue=1e-35,
Organism=Drosophila melanogaster, GI85725234, Length=100, Percent_Identity=36, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24647376, Length=100, Percent_Identity=36, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 18605; Mature: 18473

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSVNKVILIGNVGADPEIRRTQDGRPIANLRIATSESWRDRNSGERREKTEWHTVVVF
CCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEE
NEGLCKVIEQYVKKGAKLYIEGQLQTRKWQDQNGNDRYSTEIVLQGFNSTLTMLDGRGEG
CCCHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCC
GGASRGGSDLGGGGYEEYDQSRGQSSGARSGGQSNQGGNFSRDLDDDIPF
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGSVNKVILIGNVGADPEIRRTQDGRPIANLRIATSESWRDRNSGERREKTEWHTVVVF
CCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEE
NEGLCKVIEQYVKKGAKLYIEGQLQTRKWQDQNGNDRYSTEIVLQGFNSTLTMLDGRGEG
CCCHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCC
GGASRGGSDLGGGGYEEYDQSRGQSSGARSGGQSNQGGNFSRDLDDDIPF
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430; 10503543 [H]